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dc.contributor.authorRodriguez-Cano, Ruben
dc.contributor.authorLotre, Karianne
dc.contributor.authorvon Soest, Tilmann
dc.contributor.authorRognli, Eline B.
dc.contributor.authorBramness, Jørgen Gustav
dc.date.accessioned2024-09-18T07:03:10Z
dc.date.available2024-09-18T07:03:10Z
dc.date.issued2024-03-11
dc.description.abstractAims We aim to determine whether (a) experiencing loneliness in adolescence and (b) changes in loneliness from adolescence to adulthood are prospectively associated with prescriptions for a variety of psychotropic drugs in adulthood.<p> <p>Method We used data from a Norwegian population-based sample with 2602 participants, collected across four waves between 1992 and 2006. Loneliness was assessed at each wave, with survey data linked to medicinal drug prescription records from the Norwegian Prescription Database. We identified prescription histories of antipsychotics, mood stabilisers, antidepressants and benzodiazepines from 2007 to 2015, for each participant. We use latent growth curve analyses to model the relationship of adolescent loneliness and loneliness change from adolescence to adulthood, with subsequent psychotropic drugs prescription. <p>Results Adolescents with heightened loneliness, and adolescents whose loneliness increased into young adulthood, had a greater likelihood of being prescribed antipsychotics, mood stabilisers and antidepressants in adulthood. These associations remained significant after adjustment for confounders such as sociodemographic characteristics, conduct problems, substance use and mental health problems. <p>Conclusions Loneliness in adolescence and its adverse development over a span of 15 years was linked to higher risk of receiving prescriptions for antipsychotics, mood stabilisers and antidepressants later in life. The findings may indicate that loneliness increases the risk for developing psychotic disorders, bipolar disorders and major depression.en_US
dc.identifier.citationRodriguez-Cano, Lotre, von Soest, Rognli, Bramness. Loneliness in adolescence and prescription of psychotropic drugs in adulthood: 23-year longitudinal population-based and registry study. BJPsych Open. 2024;10(2)en_US
dc.identifier.cristinIDFRIDAID 2258856
dc.identifier.doi10.1192/bjo.2024.22
dc.identifier.issn2056-4724
dc.identifier.urihttps://hdl.handle.net/10037/34776
dc.language.isoengen_US
dc.publisherCambridge University Pressen_US
dc.relation.journalBJPsych Open
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2024 The Author(s)en_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0en_US
dc.rightsAttribution 4.0 International (CC BY 4.0)en_US
dc.titleLoneliness in adolescence and prescription of psychotropic drugs in adulthood: 23-year longitudinal population-based and registry studyen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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Attribution 4.0 International (CC BY 4.0)
Except where otherwise noted, this item's license is described as Attribution 4.0 International (CC BY 4.0)