Now showing items 281-300 of 1899

    • Deep learning-derived cardiovascular age shares a genetic basis with other cardiac phenotypes 

      Libiseller-Egger, Julian; Phelan, Jody E.; Attia, Zachi I.; Benavente, Ernest Diez; Campino, Susana; Friedman, Paul A.; Lopez-Jimenez, Francisco; Leon, David A.; Clark, Taane G. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-31)
      Artifcial intelligence (AI)-based approaches can now use electrocardiograms (ECGs) to provide expertlevel performance in detecting heart abnormalities and diagnosing disease. Additionally, patient age predicted from ECGs by AI models has shown great potential as a biomarker for cardiovascular age, where recent work has found its deviation from chronological age (“delta age”) to be associated ...
    • Borte bra, men hjemme best 

      Skjelbakken, Tove (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-24)
      Jeg var tre år og alene første gang jeg var i Oslo og på Rikshospitalet. Sykehuset syntes den gang at «barna var mye enklere å ha med å gjøre uten foreldrene». Kontrasten var stor da jeg 54 år senere kom tilbake til sykehuset, som nærmeste pårørende til en voksen sønn som skulle gjennomgå allogen stamcelletransplantasjon.
    • Har pasienter rett til behanding med legemidler som Beslutningsforum har avslått? 

      Lindekleiv, Haakon; Giverhaug, Trude; Henriksen, Marte Lødemel (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-21)
      Statsforvalteren i Agder har nylig gitt en pasient rett til behandling med et legemiddel som Beslutningsforum har avslått. Hvilke konsekvenser får dette?
    • Age, income and sleep duration were associated with outcomes in children participating in weight management 

      Kjetså, Ingrid; Halvorsen, Peder Andreas; Kokkvoll, Ane Sofie (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-23)
      Aim To explore associations between baseline factors and weight-related outcomes among participants enrolled in a paediatric obesity trial. Methods We included children aged 6–12 years participating in a 2-year multidisciplinary family programme who attended a postintervention follow-up 36 months from baseline (n = 62). Outcome measures were change in body mass index standard deviation score (BMI ...
    • Mercury, silver and selenium in serum before and after removal of amalgam restorations: results from a prospective cohort study in Norway 

      Björkman, Lars; Musial, Frauke; Alræk, Terje; Werner, Erik Lønnmark; Hamre, Harald J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-16)
      <p><b> Objective</b> A prospective cohort study on changes of health complaints after removal of amalgam restorations was carried out at the request of the Norwegian Directorate of Health. The aim was to provide and evaluate experimental treatment to patients with health complaints attributed to dental amalgam fillings. <p><b> Methods</b> Patients (n = 32) with medically unexplained ...
    • Validity and responsiveness of GHC-index in patients with amalgam-attributed health complaints 

      Lamu, Admassu Nadew; Robberstad, Bjarne; Hamre, Harald J.; Alræk, Terje; Musial, Frauke; Björkman, Lars (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-15)
      <p><b> Objective</b> Many patients have medically unexplained physical symptoms (MUPS); some of them attribute their health complaints to dental amalgam fillings. The aim of this study was to assess the validity and responsiveness of General Health Complaints index (GHC-index) for measuring the symptom load in MUPS patients compared to the widely used symptom outcome measure, Giessen Subjective ...
    • Leger utdannet i Bodø – hvem er de og hvor blir de av? 

      Westlie, Åsa Langen; Gaski, Margrete; Abelsen, Birgit; Grimstad, Hilde; Ofstad, Eirik Hugaas (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-10)
      <p><b> BAKGRUNN</b> Siden 2009 har inntil 24 legestudenter ved Universitetet i Tromsø årlig fullført de to siste årene av utdanningen i Bodø (kalt Bodøpakken). Vi kartla oppvekstkommune, ønsker for framtidig spesialitet blant studentene og hvor og hva studentene arbeidet med etter LIS1-tjenesten. <p><b> MATERIALE OG METODE</b> Legestudenter uteksaminert i Bodø i perioden 2012–18 fikk et ...
    • The burden of colon cancer attributable to modifiable factors—The Norwegian Women and Cancer Study 

      Lukic, Marko; Licaj, Idlir; Laaksonen, Maarit A.; Weiderpass, Elisabete; Borch, Kristin Benjaminsen; Rylander, Charlotta (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-22)
      Colon cancer is the second most frequently diagnosed cancer in women in Norway, where incidence rates of colon cancer increased 3-fold between 1955 and 2014, for unknown reasons. We aimed to assess the burden of colon cancer attributable to modifiable risk factors in Norwegian women using the data from the Norwegian Women and Cancer (NOWAC) study. Self-reported information from 35 525 women from the ...
    • First-time parents' experiences related to parental self-efficacy: A scoping review 

      Sæther, Kristin Marie; Berg, Rigmor; Holmberg Fagerlund, Bettina; Glavin, Kari; Jøranson, Nina (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-23)
      Becoming a parent for the first time is a major transition, and parental self‐efficacy (PSE) is considered an important predictor of parenting functioning. We aimed to describe and synthesize qualitative studies that explore first‐time parents' experiences related to PSE in the transition to parenthood in the first‐year postpartum. We conducted a scoping review in accordance with international ...
    • Assessment of the EarlyCDT-Lung test as an early biomarker of lung cancer in ever-smokers: A retrospective nested case-control study in two prospective cohorts 

      Wu, Wendy Yi-Ying; Haider, Zahra; Feng, Xiaoshuang; Heath, Alicia K.; Tjønneland, Anne; Agudo, Antonio; Masala, Giovanna; Robbins, Hilary A.; Huerta, María-José; Guevara, Marcela; Schulze, Matthias B.; Rodriguez-Barranco, Miguel; Vineis, Paolo; Tumino, Rosario; Kaaks, Rudolf; Fortner, Renée T.; Sieri, Sabina; Panico, Salvatore; Nøst, Therese Haugdahl; Sandanger, Torkjel M; Braaten, Tonje; Johansson, Mattias; Melin, Beatrice; Johansson, Mikael (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-28)
      The EarlyCDT-Lung test is a blood-based autoantibody assay intended to identify high-risk individuals for low-dose computed tomography lung cancer screening. However, there is a paucity of evidence on the performance of the EarlyCDT-Lung test in ever-smokers. We conducted a nested case-control study within two prospective cohorts to evaluate the risk-discriminatory performance of the EarlyCDT-Lung ...
    • Life-Course Trajectories of Physical Activity and Melanoma Risk in a Large Cohort of Norwegian Women 

      Perrier, Flavie; Ghiasvand, Reza; Lergenmuller, Simon; Robsahm, Trude Eid; Green, Adele C.; Borch, Kristin Benjaminsen; Sandanger, Torkjel M; Weiderpass, Elisabete; Rueegg, Corina Silvia; Veierød, Marit Bragelien (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-22)
      Purpose: Physical activity (PA) is a cornerstone in disease prevention and varies throughout life. A pooled analysis of cohort studies and a meta-analysis of cohort studies found positive associations between PA and melanoma risk. However, previous studies focused on PA at specific ages and often lacked information on ultraviolet radiation (UVR) exposure. Using the population-based Norwegian Women ...
    • The social gradient in Subjective Well-being (SWB) 

      Adhikari, Jaya (Mastergradsoppgave; Master thesis, 2022-11-30)
      Background: The Social gradient in Subjective wellbeing (SWB) exists in countries, and in individuals, either rich or poor, and the pattern can be seen when looking at the factors of Socio-economic Position (SEP) is a strong predictor of SWB and as well as a popular concept in health and happiness research. Aim: The main aim of this paper is firstly, to determine whether there are socio-economic ...
    • Shift work is associated with 10-year incidence of atrial fibrillation in younger but not older individuals from the general population: results from the Tromsø Study 

      Zwartkruis, VW; Sharashova, Ekaterina; Wilsgaard, Tom; De Boer, RA; Løchen, Maja-Lisa; Rienstra, Michiel (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-01)
      Objectives - Shift work is associated with myocardial infarction and stroke. We studied if shift work is also associated with incident atrial fibrillation (AF) and if this association differs, depending on sex and age.<p> <p>Methods - We studied 22 339 participants (age 37.0±9.8 years, 49% women) with paid work from the third (1986–1987), fourth (1994–1995), fifth (2001) and sixth (2007–2008) ...
    • Vertebral fractures assessed by dual-energy X-ray absorptiometry and all-cause mortality. The Tromsø Study 2007-2020 

      Johansson, Jonas; Emaus, Nina; Geelhoed, Bastiaan; Sagelv, Edvard Hamnvik; Morseth, Bente (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-16)
      Vertebral fractures have been associated with increased mortality, but findings are inconclusive, and many vertebral fractures avoid clinical attention. We investigated this association in a general population of 2,476 older adults aged ≥55 years from Tromsø, Norway, who were followed over 2007–2020, using dual-energy x-ray absorptiometry (DXA) at baseline to evaluate vertebral fractures (mild, ...
    • Dietary Intake of 91 Individual Polyphenols and 5-Year Body Weight Change in the EPIC-PANACEA Cohort 

      Gil-Lespinard, Mercedes; Castañeda, Jazmín; Almanza-Aguilera, Enrique; Gómez, Jesús Humberto; Tjønneland, Anne; Kyrø, Cecilie; Overvad, Kim; Katzke, Verena; Schulze, Matthias B.; Masala, Giovanna; Agnoli, Claudia; Santucci de Magistris, Maria; Tumino, Rosario; Sacerdote, Carlotta; Skeie, Guri; Lasheras, Cristina; Molina-Montes, Esther; Huerta, José María; Barricarte, Aurelio; Amiano, Pilar; Sonestedt, Emily; da Silva, Marisa Eleonor; Johansson, Ingegerd; Hultdin, Johan; May, Anne M.; Forouhi, Nita G.; Heath, Alicia K.; Freisling, Heinz; Weiderpass, Elisabete; Scalbert, Augustin; Zamora-Ros, Raul (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-08)
      Polyphenols are bioactive compounds from plants with antioxidant properties that may have a protective role against body weight gain, with adipose tissue and systemic oxidative stress as potential targets. We aimed to investigate the dietary intake of individual polyphenols and their association with 5-year body weight change in a sub-cohort of the European Prospective Investigation into Cancer and ...
    • Gynostemma pentaphyllum for dyslipidemia: A systematic review of randomized controlled trials 

      Dai, Ning; Zhao, Fang-Fang; Fang, Min; Pu, Feng-Lan; Kong, Ling-Yao; Liu, Jianping (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-26)
      Objective: To evaluate the lipid-lowering effect and safety of Gynostemma pentaphyllum (GP) used alone or as adjunctive therapy for dyslipidemia.<p> <p>Methods: Eight databases and three clinical trial registries were searched until January 2022. Randomized controlled trials (RCTs) assessing the effectiveness of GP for dyslipidemia were included. Trial quality was assessed using the Cochrane Risk ...
    • The neighbourhood environment and profiles of the metabolic syndrome 

      Barnett, Anthony; Martino, Erika; Knibbs, Luke D.; Shaw, Jonathan E.; Dunstan, David W.; Magliano, Dianna J.; Donaire-Gonzalez, David; Cerin, Ester (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-03)
      <p><b> Background</b> There is a dearth of studies on how neighbourhood environmental attributes relate to the metabolic syndrome (MetS) and profiles of MetS components. We examined the associations of interrelated aspects of the neighbourhood environment, including air pollution, with MetS status and profiles of MetS components. <p><b> Methods</b> We used socio-demographic and MetS-related ...
    • Baseline and lifetime alcohol consumption and risk of skin cancer in the European Prospective Investigation into Cancer and Nutrition cohort (EPIC) 

      Mahamat-Saleh, Yahya; Al-Rahmoun, Marie; Severi, Gianluca; Ghiasvand, Reza; Veierød, Marit Bragelien; Caini, Saverio; Palli, Domenico; Botteri, Edoardo; Sacerdote, Carlotta; Ricceri, Fulvio; Lukic, Marko; Sánchez, Maria J.; Pala, Valeria; Tumino, Rosario; Chiodini, Paolo; Amiano, Pilar; Colorado-Yohar, Sandra; Chirlaque, María-Dolores; Ardanaz, Eva; Bonet, Catalina; Katzke, Verena; Kaaks, Rudolf; Schulze, Matthias B.; Overvad, Kim; Dahm, Christina C.; Antoniussen, Christian S.; Tjønneland, Anne; Kyrø, Cecilie; Bueno-de-Mesquita, Bas; Manjer, Jonas; Jansson, Malin; Esberg, Anders; Mori, Nagisa; Ferrari, Pietro; Weiderpass, Elisabete; Boutron-Ruault, Marie-Christine; Kvaskoff, Marina (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-19)
      Experimental evidence suggests that alcohol induces cutaneous carcinogenesis, yet epidemiological studies on the link between alcohol intake and skin cancer have been inconsistent. The European Prospective Investigation into Cancer and Nutrition (EPIC) is a prospective cohort initiated in 1992 in 10 European countries. Alcohol intake at baseline and average lifetime alcohol intake were assessed using ...
    • Effect of remote patient monitoring for patients with chronic kidney disease who perform dialysis at home: a systematic review 

      Nygård, Henriette Tyse; Nguyen, Lien; Berg, Rigmor (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-07)
      Objective - The purpose of the systematic review was to assess the effectiveness of remote patient monitoring (RPM) follow-up compared with standard care, for patients with chronic kidney disease (CKD) who perform dialysis at home.<p> <p>Methods - We conducted a systematic review in accordance with international guidelines. We performed systematic searches for publications from 2015 to 2021 in ...
    • ‘It feels like my metabolism has shut down’. Negotiating interactional roles and epistemic positions in a primary care consultation 

      Lian, Olaug S; Nettleton, Sarah; Grange, Huw R.; Dowrick, Christopher (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-16)
      Introduction: Our aim is to explore the ways in which a patient and a general practitioner (GP) negotiate knowledge-claims stemming from different epistemic domains while dealing with a mismatch between experiential and biomedical knowledge during a clinical consultation. We interpret their interaction in relation to the sociocultural context in which their negotiation is embedded, and identify ...