Background - Dealing with the symptom burden of cancer diagnosis and treatment has led parents to seek different self-management strategies including Alternative and Complementary Medicine (CAM). The aim of this study was to perform a systematic review and meta-analysis about the use and effect of CAM modalities to treat adverse effects of conventional cancer treatment among children and young ...

Background - Epidemiological and experimental evidence has linked chronic inflammation to cancer aetiology. It is unclear whether associations for specific inflammatory biomarkers are causal or due to bias. In order to examine whether altered genetically predicted concentration of circulating cytokines are associated with cancer development, we performed a two-sample Mendelian randomisation (MR) ...

Background - The etiology and risk factors of anemia are multifactorial and varies across context. Due to the geospatial clustering of anemia, identifying risk factors for anemia should account for the geographic variability. Failure to adjust for spatial dependence whilst identifying risk factors of anemia could give spurious association. We aimed to identify risk factors of anemia using a Bayesian ...

Background: Traditional and complementary medicine (T&CM) is commonly used among cancer patients worldwide. Cancer patients in Norway mainly visit T&CM providers in addition to conventional health care services. It is not known how their utilization of T&CM providers influences their use of conventional health care services. The aim of this study was to investigate the difference between the ...

The thesis has focused on asthma, AR and AD in children in a limited geographical region over a limited period of time and has studied the prevalence trends, geographical differences in prevalence and the biomarker s-ECP. These are the main findings in the five papers published: <ul id = «mylist»> <li> The prevalence of asthma and allergy in north Norwegian primary schoolchildren increased ...

BACKGROUND: CA125 is the best available yet insufficiently sensitive biomarker for early detection of ovarian cancer. There is a need to identify novel biomarkers, which individually or in combination with CA125 can achieve adequate sensitivity and specificity for the detection of earlier-stage ovarian cancer.<p> <p>METHODS: In the European Prospective Investigation into Cancer and Nutrition ...

Background: Infammation has been hypothesized to play a role in the development and progression of breast can‑ cer and might diferently impact breast cancer risk among pre and postmenopausal women. We performed a nested case-control study to examine whether pre-diagnostic circulating concentrations of adiponectin, leptin, c-reactive protein (CRP), tumour necrosis factor-α, interferon-γ and 6 ...

The present thesis is a study of how doctors learn to make clinical decisions; decisions about diagnosis and therapy of the individual patient in the context of the clinic. It is based on ethnographic fieldwork and anthropological analysis carried out in 2006-2009. The key informants are nine doctors who go through internship and the empirical field is the wards and clinics of regional hospitals, ...

This thesis highlights several clinically important questions related to bone loss the first year following stroke and with regard to bone mass at stroke onset:<br> Lack of mobility and weight bearing early after stroke is an important factor for the greater bone loss in the proximal femur on the paretic side. Relearning to walk within the first two month after stroke, even with support of another ...

Stroke is the second leading cause of death in the world and is responsible for a high percentage of major disability, requiring substantial resources spent on care and rehabilitation. Atherosclerosis due to lipid accumulation in the vessel wall with formation of stenotic atheromatous plaques in the carotid bifurcation and/or the internal carotid artery is an important cause of stroke. In ...