Viser treff 201-220 av 1899

    • Cancer detection for white urban Americans 

      Møllersen, Kajsa; Bongo, Lars Ailo; Tafavvoghi, Masoud (Conference object; Konferansebidrag, 2023-06)
      Development, validation and comparison of machine learning methods require access to data, sometimes lots of data. Within health applications, data sharing can be restricted due to patient privacy, and the few publicly available data sets become even more valuable for the machine learning community. One such type of data are H&E whole slide images (WSI), which are stained tumour tissue, used in ...
    • Prevalence of undernutrition among pregnant women and its differences across relevant subgroups in rural Ethiopia: a community-based cross-sectional study 

      Chea, Nana; Tegene, Yadessa; Astatkie, Ayalew; Spigt, Marcus (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-10)
      Background - Maternal undernutrition is one of the commonest public health problems in many low- and middle-income countries where generally more than 20% of women are undernourished. It is more common in rural areas due to unclear factors. Therefore, the aim of this study was to investigate the prevalence of undernutrition in general and in subgroups and determine risk factors among pregnant women ...
    • Circulating amino acid levels and colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition and UK Biobank cohorts 

      Rothwell, Joseph A.; Bešević, Jelena; Dimou, Niki; Breeur, Marie; Murphy, Neil; Jenab, Mazda; Wedekind, Roland; Viallon, Vivian; Ferrari, Pietro; Achaintre, David; Gicquiau, Audrey; Rinaldi, Sabina; Scalbert, Augustin; Huybrechts, Inge; Prehn, Cornelia; Adamski, Jerzy; Cross, Amanda J.; Keun, Hector; Chadeau-Hyam, Marc; Boutron-Ruault, Marie-Christine; Overvad, Kim; Dahm, Christina C.; Nøst, Therese Haugdahl; Sandanger, Torkjel M; Skeie, Guri; Zamora-Ros, Raul; Tsilidis, Kostas K.; Eichelmann, Fabian; Schulze, Matthias B.; van Guelpen, Bethany; Vidman, Linda; Sánchez, Maria-José; Amiano, Pilar; Ardanaz, Eva; Smith-Byrne, Karl; Travis, Ruth; Katzke, Verena; Kaaks, Rudolf; Derksen, Jeroen W. G.; Colorado-Yohar, Sandra; Tumino, Rosario; Bueno-de-Mesquita, Bas; Vineis, Paolo; Palli, Domenico; Pasanisi, Fabrizio; Eriksen, Anne Kirstine; Tjønneland, Anne; Severi, Gianluca; Gunter, Marc J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-28)
      Background Amino acid metabolism is dysregulated in colorectal cancer patients; however, it is not clear whether pre-diagnostic levels of amino acids are associated with subsequent risk of colorectal cancer. We investigated circulat‑ ing levels of amino acids in relation to colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) and UK Biobank ...
    • Selvrapportert psykisk helse, ensomhet og sosial støtte blant innbyggere i Tromsø kommune, i grupper av kjønn, alder og sosioøkonomisk status: En del av Fylkeshelseundersøkelsen i Troms og Finnmark 2019 

      Endresen, Hege (Mastergradsoppgave; Master thesis, 2023-08-01)
      Rationale for studie: Tromsø kommune har behov for et kunnskapsgrunnlag i sitt folkehelsearbeid. Det er spesielt viktig å undersøke grad av psykisk uhelse, ensomhet og sosial støtte i ulike grupper i befolkningen, da tidligere studier har vist forskjeller mellom kjønn, alders- og utdanningsgrupper. Eksisterende datakilder, som inkluderer folkehelserapporter fra Tromsøundersøkelsen og FHI’s ...
    • LIS1-leger og medisinsk usikkerhet – en kvalitativ studie 

      Ofstad, Eirik Hugaas; Asdal, Karoline; Nightingale, Bruno; Han, Paul K.; Gregersen, Trine Ammentorp; Gulbrandsen, Pål (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-29)
      BAKGRUNN - Hvordan norske leger håndterer medisinsk usikkerhet, er lite studert. Formålet med studien var å undersøke hvordan leger i spesialisering del 1 (LIS1-leger) opplever og håndterer usikkerhet i en klinisk hverdag.<p> <p>MATERIALE OG METODER - Ti LIS1-leger ved to sykehus ble rekruttert til intervjuer etter svarmønsteranalyse fra et kartleggende spørreskjema. Intervjuene ble analysert ...
    • Development of Hypertension and Diabetes Mellitus, and Associated Factors, Among Adult HIV Patients in Ethiopia 

      Tegene, Yadessa; Mengesha, Selamawit; Putman, Erin; Toma, Alemayehu; Spigt, Marcus (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-16)
      Background: Medical improvements and increased access to treatment have turned HIV from a highly fatal disease into a treatable and controllable disease. With the improvement in lifespan, HIV patients face increasing morbidity and mortality from chronic comorbidities (hypertension and diabetes mellitus). There is, nevertheless, a paucity of information on the scale of HIV noncommunicable disease ...
    • Comparing the sociodemographic characteristics of participants and non-participants in the population-based Tromsø Study 

      Vo, Chi Quynh; Samuelsen, Per-Jostein; Sommerseth, Hilde Leikny; Wisløff, Torbjørn; Wilsgaard, Tom; Eggen, Anne Elise (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-29)
      Background Diferences in the sociodemographic characteristics of participants and non-participants in populationbased studies may introduce bias and reduce the generalizability of research fndings. This study aimed to compare the sociodemographic characteristics of participants and non-participants of the seventh survey of the Tromsø Study (Tromsø7, 2015–16), a population-based health survey.<p> ...
    • Sputum bacterial load and bacterial composition correlate with lung function and are altered by long-term azithromycin treatment in children with HIV-associated chronic lung disease 

      Abotsi, Regina E.; Dube, Felix S.; Rehman, Andrea M.; Claassen-Weitz, Shantelle; Xia, Yao; Simms, Victoria; Mwaikono, Kilaza S.; Gardner-Lubbe, Sugnet; McHugh, Grace; Ngwira, Lucky G.; Kwambana-Adams, Brenda; Heyderman, Robert S.; Odland, Jon Øyvind; Ferrand, Rashida A.; Nicol, Mark P. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-20)
      Background - Long-term azithromycin (AZM) treatment reduces the frequency of acute respiratory exacerbation in children and adolescents with HIV-associated chronic lung disease (HCLD). However, the impact of this treatment on the respiratory bacteriome is unknown.<p> <p>Method - African children with HCLD (defined as forced expiratory volume in 1 s z-score (FEV1z) less than − 1.0 with no ...
    • Legacy perfluoroalkyl acids and their oxidizable precursors in plasma samples of Norwegian women 

      Miranda Fernandes Coelho, Ana Carolina; Cioni, Lara; Van Dreunen, Wendy; Berg, Vivian; Rylander, Karin Charlotta Maria; Urbarova, Ilona Halva; Herzke, Dorte; Sandanger, Torkjel M (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-12)
      Humans are exposed to perfluoroalkyl acids (PFAA) mainly through direct pathways, such as diet and drinking water, but indirect exposure also occurs when PFAA precursors break down to form legacy PFAA. Exposure to PFAA precursors raises particular concern, as neither the exposure nor the precursors themselves have been well described. In the present study, we aimed to assess the indirect contribution ...
    • Associations between dietary inflammatory scores and biomarkers of inflammation in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort 

      Lécuyer, Lucie; Laouali, Nasser; Viallon, Vivian; Artaud, Fanny; Hébert, James R.; Shivappa, Nitin; Agudo, Antonio; Tjønneland, Anne; Mellemkjær, Lene; Kaaks, Rudolf; Katzke, Verena A.; Schulze, Matthias B.; Frenoy, Pauline; Mancini, Francesca Romana; De Magistris, Maria Santucci; Macciotta, Alessandra; Masala, Giovanna; Agnoli, Claudia; Tumino, Rosario; Boer, Jolanda M.A.; Verschuren, W.M. Monique; Jensen, Torill; Olsen, Karina Standahl; Skeie, Guri; Chirlaque, María-Dolores; Petrova, Dafina; Castro-Espin, Carlota; Quirós, J. Ramón; Guevara, Marcela; Amiano, Pilar; Borné, Yan; Sandström, Maria; Nilsson, Lena Maria; Heath, Alicia K.; Mayen, Ana-Lucia; Huybrechts, Inge; Weiderpass, Elisabete; Boutron-Ruault, Marie-Christine; Dossus, Laure; Rinaldi, Sabina; Truong, Thérèse (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-17)
      Background - Since the first version of the dietary inflammatory index (DII®) developed in the past decade, several other versions have been developed. However, to date no study has attempted to compare these versions with respect to their associations with biomarkers of inflammation.<p> <p>Objective - We aimed to investigate the relationship between four dietary inflammatory scores [DII, two ...
    • The impact of coding germline variants on contralateral breast cancer risk and survival 

      Morra, Anna; Mavaddat, Nasim; Muranen, Taru A.; Ahearn, Thomas U.; Allen, Jamie; Andrulis, Irene L.; Auvinen, Päivi; Becher, Heiko; Behrens, Sabine; Blomqvist, Carl; Bojesen, Stig E.; Bolla, Manjeet K.; Brauch, Hiltrud; Camp, Nicola J.; Carvalho, Sara; Castelao, Jose E.; Cessna, Melissa H.; Chang-Claude, Jenny; Chenevix-Trench, Georgia; Sahlberg, Guro Kristine Kleivi; Børresen-Dale, Anne-Lise; Gram, Inger Torhild; Olsen, Karina Standahl; Engebråten, Olav; Naume, Bjørn; Geisler, Jürgen; Grenaker, Grethe Irene; Czene, Kamila; Decker, Brennan; Dennis, Joe; Dörk, Thilo; Dorling, Leila; Dunning, Alison M.; Ekici, Arif B.; Eriksson, Mikael; Evans, D. Gareth; Fasching, Peter A.; Figueroa, Jonine D.; Flyger, Henrik; Gago-Dominguez, Manuela; García-Closas, Montserrat; Geurts-Giele, Willemina R.R.; Giles, Graham G.; Guénel, Pascal; Gündert, Melanie; Hahnen, Eric; Hall, Per; Hamann, Ute; Harrington, Patricia A.; He, Wei; Heikkilä, Päivi; Hooning, Maartje J.; Hoppe, Reiner; Howell, Anthony; Humphreys, Keith; Kristensen, Vessela N.; Mannermaa, Arto; Manoochehri, Mehdi; Manoukian, Siranoush; Margolin, Sara; Mavroudis, Dimitrios; Milne, Roger L.; Mulligan, Anna Marie; Newman, William G.; Park-Simon, Tjoung-Won; Peterlongo, Paolo; Pharoah, Paul D.P.; Rhenius, Valerie; Saloustros, Emmanouil; Sawyer, Elinor J.; Schmutzler, Rita K.; Shah, Mitul; Spurdle, Amanda B.; Tomlinson, Ian; Truong, Thérèse; van Veen, Elke M.; Vreeswijk, Maaike P.G.; Wang, Qin; Wendt, Camilla; Yang, Xiaohong R.; Nevanlinna, Heli; Devilee, Peter; Easton, Douglas F.; Schmidt, Marjanka K. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-23)
      Evidence linking coding germline variants in breast cancer (BC)-susceptibility genes other than BRCA1, BRCA2, and CHEK2 with contralateral breast cancer (CBC) risk and breast cancer-specific survival (BCSS) is scarce. The aim of this study was to assess the association of protein-truncating variants (PTVs) and rare missense variants (MSVs) in nine known (ATM, BARD1, BRCA1, BRCA2, CHEK2, PALB2, RAD51C, ...
    • Dietary fatty acids and endometrial cancer risk within the European Prospective Investigation into Cancer and Nutrition 

      Yammine, S.G.; Huybrechts, I.; Biessy, C.; Dossus, L.; Panico, S.; Sánchez, M.J.; Benetou, V.; Turzanski-Fortner, R.; Katzke, V.; Idahl, A.; Skeie, Guri; Olsen, Karina Standahl; Tjønneland, A.; Halkjaer, J.; Colorado-Yohar, S.; Heath, A.K.; Sonestedt, E.; Sartor, H.; Schulze, M.B.; Palli, D.; Crous-Bou, M.; Dorronsoro, A.; Overvad, K.; Gurrea, A. Barricarte; Severi, G.; Vermeulen, R.C.H.; Sandanger, Torkjel M; Travis, R.C.; Key, T.; Amiano, P.; Van Guelpen, Guelpen; Johansson, Mattias; Sund, M.; Tumino, R.; Wareham, N.; Sacerdote, C.; Krogh, V.; Brennan, P.; Riboli, E.; Weiderpass, Elisabete; Gunter, M.J.; Chajès, V. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-16)
      Background - Diet may impact important risk factors for endometrial cancer such as obesity and inflammation. However, evidence on the role of specific dietary factors is limited. We investigated associations between dietary fatty acids and endometrial cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC).<p> <p>Methods - This analysis includes 1,886 incident ...
    • Risk prediction of atrial fibrillation and its complications in the community using hs troponin I 

      Börschel, Christin S.; Geelhoed, Bastiaan; Niiranen, Teemu; Camen, Stephan; Donati, Maria Benedetta; Havulinna, Aki S.; Gianfagna, Francesco; Palosaari, Tarja; Jousilahti, Pekka; Kontto, Jukka; Vartiainen, Erkki; Ojeda, Francisco M.; den Ruijter, Hester M.; Costanzo, Simona; de Gaetano, Giovanni; Di Castelnuovo, Augusto; Linneberg, Allan; Vishram-Nielsen, Julie K.; Løchen, Maja-Lisa; Koenig, Wolfgang; Jørgensen, Torben; Kuulasmaa, Kari; Blankenberg, Stefan; Iacoviello, Licia; Zeller, Tanja; Söderberg, Stefan; Salomaa, Veikko; Schnabel, Renate B. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-05)
      Aims - Atrial fibrillation (AF) is becoming increasingly common. Traditional cardiovascular risk factors (CVRF) do not explain all AF cases. Blood-based biomarkers reflecting cardiac injury such as high-sensitivity troponin I (hsTnI) may help close this gap.<p> <p>Methods - We investigated the predictive ability of hsTnI for incident AF in 45,298 participants (median age 51.4 years, 45.0% men) ...
    • Evidence synthesis of Chinese medicine for monkeypox: Suggestions from other contagious pox-like viral diseases 

      Rong, Hong-Guo; Zhang, Xiao-Wen; Han, Mei; Sun, Xin; Wu, Xiao-Dan; Lai, Xiao-Zhen; Shen, Chen; Yu, Wei-Jie; Fang, Hai; Fei, Yu-Tong; Liu, Jianping (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-13)
      Background: Monkeypox, a zoonotic disease caused by an Orthopoxvirus, presents an etiology similar to smallpox in humans. Currently, there are no licensed treatments for human monkeypox, so clear and urgent research on its prophylaxis and treatment is needed.<p> <p>Objective: The purpose of this study was to explore the evidence of Chinese medicine for contagious pox-like viral diseases and provide ...
    • Fra lokalt til nasjonalt utbrudd av Pseudomonas aeruginosa 

      Asfeldt, anne mette; Myrbakk, Torni; Grimnes, Gro; Kildal, Anders Benjamin; Pedersen, Torunn Annie; Littauer, Pia; Bogetvedt, Tina; Kroken, Bjørn Anders; Nerskogen, Birgith Jørgensen; Høgli, June Utnes; Åsheim, Sandra Elena (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-29)
      Utbrudd som rammer flere sykehus, krever god koordinering. Folkehelseinstituttets rolle i dette arbeidet bør styrkes, og vi trenger bedre systemer for utbruddsovervåking, rask tilgang til genteknologiske verktøy samt metoder for mikrobiologiske undersøkelser av miljø og utstyr.
    • Symptoms and signs of urogenital cancer in primary care 

      Holtedahl, Knut Arne; Borgquist, Lars; Donker, Gé A.; Buntinx, Frank; Weller, David; Campbell, Christine; Månsson, Jörgen; Hammersley, Victoria; Braaten, Tonje Bjørndal; Parajuli, Ranjan (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-04-26)
      Background - Urogenital cancers are common, accounting for approximately 20% of cancer incidence globally. Cancers belonging to the same organ system often present with similar symptoms, making initial management challenging. In this study, 511 cases of cancer were recorded after the date of consultation among 61,802 randomly selected patients presenting in primary care in six European countries: a ...
    • Guidance on C-reactive protein point-of-care testing and complementary strategies to improve antibiotic prescribing for adults with lower respiratory tract infections in primary care 

      Van Hecke, Oliver; Bjerrum, Lars; Gentile, Ivan; Hopstaken, Rogier; Melbye, Hasse; Plate, Andreas; Verbakel, Jan Y.; Llor, Carl; Staiano, Annamaria (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-30)
      The world faces the threat of increasing antimicrobial resistance, and there is growing consensus that swift action must be taken to improve the rational use of antibiotics and increase the stewardship of antibiotics to safeguard this key resource in modern healthcare. This paper provides the perspective of an international group of experts on the role of C-reactive protein point-of-care testing ...
    • Reproductive and hormonal factors and risk of renal cell carcinoma among women in the European Prospective Investigation into Cancer and Nutrition 

      Clasen, Joanna L.; Mabunda, Rita; Heath, Alicia K.; Kaaks, Rudolf; Katzke, Verena; Schulze, Matthias B.; Birukov, Anna; Tagliabue, Giovanna; Chiodini, Paolo; Tumino, Rosario; Milani, Lorenzo; Braaten, Tonje Bjørndal; Gram, Inger Torhild; Lukic, Marko; Luján-Barroso, Leila; Rodriguez-Barranco, Miguel; Chirlaque, María-Dolores; Ardanaz, Eva; Amiano, Pilar; Manjer, Jonas; Huss, Linnea; Ljungberg, Börje; Travis, Ruth; Smith-Byrne, Karl; Gunter, Marc; Johansson, Matthias; Rinaldi, Sabina; Weiderpass, Elisabete; Riboli, Elio; Cross, Amanda J.; Muller, David C. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-03)
      Background - Renal cell carcinoma (RCC) is twice as common among men compared with women, and hormonal factors have been suggested to partially explain this difference. There is currently little evidence on the roles of reproductive and hormonal risk factors in RCC aetiology.<p> <p>Materials & Methods - We investigated associations of age at menarche and age at menopause, pregnancy-related factors, ...
    • Dietary vitamin D intake and the bladder cancer risk: A pooled analysis of prospective cohort studies 

      Boot, Iris W.A.; Wesselius, Anke; Yu, Evan Y.W.; White, Emily; Brustad, Magritt; Marques, Chloé; Ljungberg, Borje; Zeegers, Maurice P. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-22)
      Background & aims - Diet may play an essential role in the aetiology of bladder cancer (BC). Vitamin D is involved in various biological functions which have the potential to prevent BC development. Besides, vitamin D also influences the uptake of calcium and phosphorus, thereby possibly indirectly influencing the risk of BC. The aim of the present study was to investigate the relation between vitamin ...
    • “My cousin said to me ...” Patients’ use of 3rd-party references to facilitate shared decision-making during naturally occurring primary care consultations. 

      Lian, Olaug S; Nettleton, Sarah Joan; Grange, Huw Robert; Dowrick, Christopher (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-30)
      In this paper, we explore the ways in which patients invoke third parties to gain decision-making influence in clinical consultations. The patients’ role in decision-making processes is often overlooked, and this interactional practice has rarely been systematically studied. Through a contextual narrative exploration of 42 naturally occurring consultations between patients (aged 22–84) and general ...