Institutt for samfunnsmedisin: Nye registreringer

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    • A Prospective Diet-Wide Association Study for Risk of Colorectal Cancer in EPIC 

      Papadimitriou, Nikos; Bouras, Emmanouil; van den Brandt, Piet A.; Muller, David C.; Papadopoulou, Areti; Heath, Alicia K.; Critselis, Elena; Gunter, Marc; Vineis, Paolo; Ferrari, Pietro; Weiderpass, Elisabete; Boeing, Heiner; Bastide, Nadia; Merritt, Melissa A.; Lopez, David S.; Bergmann, Manuela M.; Perez-Cornago, Aurora; Schulze, Matthias; Skeie, Guri; Srour, Bernard; Eriksen, Anne Kirstine; Boden, Stina; Johansson, Ingegerd; Nøst, Therese Haugdahl; Lukic, Marko; Ricceri, Fulvio; Ericson, Ulrika; Huerta, José-Maria; Dahm, Christina C.; Agnoli, Claudia; Amiano, Pilar; Tjønneland, Anne; Barricarte, Aurelio; Bueno-de-Mesquita, Bas; Ardanaz, Eva; Berntsson, Jonna; Sánchez, Maria-Jose; Tumino, Rosario; Panico, Salvatore; Katzke, Verena; Jakszyn, Paula; Masala, Giovanna; Derksen, Jeroen W.G.; Quirós, J. Ramón; Severi, Gianluca; Cross, Amanda J.; Riboli, Ellio; Tzoulaki, Ioanna; Tsilidis, Konstantinos K. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-24)
      Background & Aims - Evidence regarding the association of dietary exposures with colorectal cancer (CRC) risk is not consistent with a few exceptions. Therefore, we conducted a diet-wide association study (DWAS) in the European Prospective Investigation into Cancer and Nutrition (EPIC) to evaluate the associations between several dietary exposures with CRC risk.<p> <p>Methods - The association ...

    • Plasma concentrations of persistent organic pollutants and pancreatic cancer risk 

      Porta, Miquel; Gasull, Magda; Pumarega, José; Kiviranta, Hannu; Rantakokko, Panu; Raaschou-Nielsen, Ole; Bergdahl, Ingvar A.; Sandanger, Torkjel M; Agudo, Antoni; Rylander, Charlotta; Nøst, Therese Haugdahl; Donat-Vargas, Carolina; Aune, Dagfinn; Heath, Alicia K; Cirera, Lluís; Goni-Irigoyen, Fernando; Alguacil, Juan; Giménez-Robert, Álex; Tjønneland, Anne; Sund, Malin; Overvad, Kim; Romana Mancini, Francesca; Rebours, Vinciane; Boutron-Ruault, Marie Christine; Kaaks, Rudolf; Schulze, Matthias B.; Trichopoulou, Antonia; Palli, Domenico; Grioni, Sara; Tumino, Rosario; Naccarati, Alessio; Panico, Salvatore; Vermeulen, Roel; Ramón Quirós, J; Rodríguez-Barranco, Miguel; Colorado-Yohar, Sandra M.; Chirlaque, María Dolores; Ardanaz, Eva; Wareham, Nick; Key, Tim; Johansson, Mattias; Murphy, Neil; Ferrari, Pietro; Huybrechts, Inge; Chajes, Veronique; Gonzalez, Carlos Alberto; de Mesquita, Bas Bueno; Gunter, Marc; Vainio, Elisabete Weiderpass; Riboli, Elio; Duell, Eric J; Katzke, Verena; Vineis, Paolo (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-14)
      Background: Findings and limitations of previous studies on persistent organic pollutants (POPs) and pancreatic cancer risk support conducting further research in prospective cohorts.<p> Methods: We conducted a prospective case-control study nested within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. Participants were 513 pancreatic cancer cases and 1020 matched ...

    • Assessing the impact of exposome on the course of chronic obstructive pulmonary disease and cystc fibrosis: The REMEDIA European Project Approach 

      Benjdir, Manon; Audureau, Etienne; Beresniak, Ariel; Coll, Patrice; Epaud, Ralph; Fiedler, Kristina; Jacquemin, B; Niddam, Laurent; Pandis, Spyros N.; Pohlmann, Gerhard; Sandanger, Torkjel M; Simmons, Kai; Sorensen, Mette; Wagner, Patrick; Lanone, Sophie (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-26)
      Because of the direct interaction of lungs with the environment, respiratory diseases are among the leading causes of environment-related deaths in the world. Chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF) are two highly debilitating diseases that are of particular interest in the context of environmental studies; they both are characterized by a similar progressive loss of ...

    • “I’m not the doctor; I’m just the patient”: Patient agency and shared decision-making in naturally occurring primary care consultations 

      Lian, Olaug S; Nettleton, Sarah; Grange, Huw R.; Dowrick, Christopher (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-30)
      Objectives: To explore interactional processes in which clinical decisions are made in situ during medical consultations, particularly the ways in which patients show agency in decision-making processes by proposing and opposing actions, and which normative dimensions and role-expectations their engagement entail.<p> Methods: Narrative analysis of verbatim transcripts of 22 naturally occurring ...

    • Food biodiversity and total and cause-specific mortality in 9 European countries: An analysis of a prospective cohort study 

      Hanley-Cook, Giles T.; Huybrechts, Inge; Biessy, Carine; Remans, Roseline; Kennedy, Gina; Deschasaux-Tanguy, Mélanie; Murray, Kris A.; Touvier, Mathilde; Skeie, Guri; Kesse-Guyot, Emmanuelle; Argaw, Alemayehu; Casagrande, Corinne; Nicolas, Geneviève; Vineis, Paolo; Millett, Christopher J.; Weiderpass, Elisabete; Ferrari, Pietro; Dahm, Christina C.; Bueno-De-Mesquita, H. Bas; Sandanger, Torkjel M; Ibsen, Daniel B.; Freisling, Heinz; Ramne, Stina; Jannasch, Franziska; van der Schouw, Yvonne T.; Schulze, Matthias B.; Tsilidis, Konstantinos K.; Tjønneland, Anne; Ardanaz, Eva; Bodén, Stina; Cirera, Lluís; Gargano, Giuliana; Halkjær, Jytte; Jakszyn, Paula; Johansson, Ingegerd; Katzke, Verena; Masala, Giovanna; Panico, Salvatore; Rodriguez-Barranco, Miguel; Sacerdote, Carlotta; Srour, Bernard; Tumino, Rosario; Riboli, Elio; Gunter, Marc J.; Jones, Andrew D.; Lachat, Carl (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-18)
      Background<p> <p>Food biodiversity, encompassing the variety of plants, animals, and other organisms consumed as food and drink, has intrinsic potential to underpin diverse, nutritious diets and improve Earth system resilience. Dietary species richness (DSR), which is recommended as a crosscutting measure of food biodiversity, has been positively associated with the micronutrient adequacy of diets ...

    • Cognitive impairment in older cancer patients treated with first-line chemotherapy 

      Dos Santos, Mélanie; Licaj, Idlir; Bellera, Carine; Cany, Laurent; Binarelli, Giulia; Soubeyran, Pierre; Joly, Florence (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-07)
      Older cancer patients are vulnerable to chemotherapy-related cognitive impairment. We prospectively evaluated cognitive impairment and its predictive factors during first-line chemotherapy in elderly cancer patients (≥70 years). Cognitive function was evaluated by the Mini-Mental State Examination (MMSE) with adjusted scores for age and sociocultural level. Multidimensional geriatric assessment was ...

    • Lifestyle correlates of eight breast cancer-related metabolites: a cross-sectional study within the EPIC cohort 

      His, Mathilde; Viallon, Vivian; Dossus, Laure; Schmidt, Julie A.; Travis, Ruth C.; Gunter, Marc; Overvad, Kim; Kyrø, Cecilie; Tjønneland, Anne; Lécuyer, Lucie; Rothwell, Joseph A.; Severi, Gianluca; Johnson, Theron; Katzke, Verena; Schulze, Matthias B.; Masala, Giovanna; Sieri, Sabina; Panico, Salvatore; Tumino, Rosario; Macciotta, Alessandra; Boer, Jolanda M. A.; Monninkhof, Evelyn; Olsen, Karina Standahl; Nøst, Therese Haugdahl; Sandanger, Torkjel M; Agudo, Antonio; Sánchez, Maria-Jose; Amiano, Pilar; Colorado-Yohar, Sandra; Ardanaz, Eva; Vidman, Linda; Winkvist, Anna; Heath, Alicia K.; Weiderpass, Elisabete; Huybrechts, Inge; Rinaldi, Sabina (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-10)
      Background: Metabolomics is a promising molecular tool for identifying novel etiological pathways leading to cancer. In an earlier prospective study among pre- and postmenopausal women not using exogenous hormones, we observed a higher risk of breast cancer associated with higher blood concentrations of one metabolite (acetylcarnitine) and a lower risk associated with higher blood concentrations of ...

    • Pasienter med strømgjennomgang fra lavspenning henvist til et akuttmottak 

      Svendsen, Trude Beathe; Bærheim, Dina; Dale, Jostein; Goffeng, Lars Ole; Vesterfjell, Svend Peder; Ofstad, Eirik Hugaas; Næss-Pleym, Lars E.; Bjørnsen, Lars Petter Bache-Wiig (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-13)
      <p><b>BAKGRUNN</b> Pasienter utsatt for strøm henvises ofte til akuttmottaket, men det er ulike retningslinjer for hvordan disse bør håndteres. Vi beskriver her pasienter med strømgjennomgang fra lavspenning i akuttmottaket ved St. Olavs hospital. <p><b>METODE OG MATERIALE</b> Retrospektive data fra pasienter henvist til akuttmottaket etter strømgjennomgang fra lavspenning (< 1 000 volt) i ...

    • Dietary advanced glycation end-products and colorectal cancer risk in the European prospective investigation into cancer and nutrition (EPIC) study 

      Aglago, Elom K.; Mayén, Ana-Lucia; Knaze, Viktoria; Freisling, Heinz; Fedirko, Veronika; Hughes, David J.; Jiao, Li; Eriksen, Anne Kirstine; Tjønneland, Anne; Boutron-Ruault, Marie-Christine; Rothwell, Joseph A.; Severi, Gianluca; Kaaks, Rudolf; Katzke, Verena; Schulze, Matthias B.; Birukov, Anna; Palli, Domenico; Sieri, Sabina; de Magistris, Maria Santucci; Tumino, Rosario; Ricceri, Fulvio; Bueno-De-Mesquita, Bas; Derksen, Jeroen W.G.; Skeie, Guri; Gram, Inger Torhild; Sandanger, Torkjel M; Quirós, J. Ramón; Lujan-Barroso, Leila; Sánchez, Maria-Jose; Amiano, Pilar; Chirlaque, María-Dolores; Barricarte, Aurelio; Johansson, Ingegerd; Manjer, Jonas; Perez-Cornago, Aurora; Weiderpass, Elisabete; Gunter, Marc; Heath, Alicia K.; Schalkwijk, Casper G.; Jenab, Mazda (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-08)
      Dietary advanced glycation end-products (dAGEs) have been hypothesized to be associated with a higher risk of colorectal cancer (CRC) by promoting inflammation, metabolic dysfunction, and oxidative stress in the colonic epithelium. However, evidence from prospective cohort studies is scarce and inconclusive. We evaluated CRC risk associated with the intake of dAGEs in the European Prospective ...

    • Dietary fatty acids, macronutrient substitutions, food sources and incidence of coronary heart disease: Findings from the EPIC-CVD case-cohort study across nine european countries 

      Steur, Marinka; Johnson, Laura; Sharp, Stephen J.; Imamura, Fumiaki; Sluijs, Ivonne; Key, Timothy J.; Wood, Angela M.; Chowdhury, Rajiv; Guevara, Marcela; Jakobsen, Marianne Uhre; Johansson, Ingegerd; Koulman, Albert; Overvad, Kim; Sánchez, Maria-José; van der Schouw, Yvonne T.; Trichopoulou, Antonia; Weiderpass, Elisabete; Wennberg, Maria; Zheng, Ju-Sheng; Boeing, Heiner; Boer, Jolanda M. A.; Boutron-Ruault, Marie-Christine; Ericson, Ulrika; Heath, Alicia K.; Huybrechts, Inge; Imaz, Liher; Kaaks, Rudolf; Krogh, Vittorio; Kühn, Tilman; Kyrø, Cecilie; Masala, Giovanna; Melander, Olle; Moreno-Iribas, Conchi; Panico, Salvatore; Quirós, José R.; Rodríguez-Barranco, Miguel; Sacerdote, Carlotta; Santiuste, Carmen; Skeie, Guri; Tjønneland, Anne; Tumino, Rosario; Monique Verschuren, Verschuren; Zamora-Ros, Raúl; Dahm, Christina C.; Perez-Cornago, Aurora; Schulze, Matthias B.; Tong, Tammy Y.N.; Riboli, Elio; Wareham, Nick; Danesh, John; Butterworth, Adam S.; Forouhi, Nita G. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-07)
      BACKGROUND: There is controversy about associations between total dietary fatty acids, their classes (saturated fatty acids [SFAs], monounsaturated fatty acids, and polyunsaturated fatty acids), and risk of coronary heart disease (CHD). Specifically, the relevance of food sources of SFAs to CHD associations is uncertain.<p> METHODS AND RESULTS: We conducted a case-cohort study involving 10 529 ...

    • Clinical and economic impact of universal varicella vaccination in Norway: A modeling study 

      Pawaskar, Manjiri; Burgess, Colleen; Pillsbury, Matthew; Wisløff, Torbjørn (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-08)
      Background<p> <p>Norway has not implemented universal varicella vaccination, despite the considerable clinical and economic burden of varicella disease.<p> Methods<p> <p>An existing dynamic transmission model of varicella infection was calibrated to age-specific seroprevalence rates in Norway. Six two-dose vaccination strategies were considered, consisting of combinations of two formulations ...

    • Clinical Reasoning - a Scotoma in the Medical Gaze? 

      Risør, Torsten; Rodriguez, Charo (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-07)
      Clinical reasoning is a core activity in everyday clinical work, but is also a well-developed field of research with scholarly papers, reviews, books, conferences and medical curriculum activities. In this body of knowledge, and although it remains a complex construct [1], clinical reasoning is generally defined as the cognitive processes and mental structures that physicians mobilise to decide on ...

    • Historical foundations and contemporary expressions of a right to health care in Circumpolar Indigenous contexts: A cross-national analysis 

      Lavoie, Josée G.; Stoor, Jon Petter; Rink, Elizabeth; Cueva, Katie; Gladun, Elena; Larsen, Christina Viskum Lytken; Akearok, Gwen Healey; Kanayurak, Nicole (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-14)
      Although numerous comparative Indigenous health policy analyses exist in the literature, to date, little attention has been paid to comparative analyses of Circumpolar health policy and the impact these policies may have on Indigenous peoples’ rights to health. In this article, we ground our discussion of Indigenous peoples’ right to access culturally appropriate and responsive health care within ...

    • Prospective analysis of circulating metabolites and endometrial cancer risk 

      Dossus, Laure; Kouloura, Eirini; Biessy, Carine; Viallon, Vivian; Siskos, Alexandros P.; Dimou, Niki; Rinaldi, Sabina; Merritt, Melissa A.; Allen, Naomi E.; Fortner, Renée T.; Kaaks, Rudolf; Weiderpass, Elisabete; Gram, Inger Torhild; Rothwell, Joseph A.; Lécuyer, Lucie; Severi, Gianluca; Schulze, Matthias B.; Nøst, Therese Haugdahl; Crous-Bou, Marta; Sánchez, Maria-Jose; Amiano, Pilar; Colorado-Yohar, Sandra; Barricarte, Aurelio; Schmidt, Julie A.; Palli, Domenico; Agnoli, Claudia; Tumino, Rosario; Sacerdote, Carlotta; Mattiello, Amalia; Vermeulen, Roel; Heath, Alicia K.; Christakoudi, Sofia; Tsilidis, Konstantinos K.; Travis, Ruth C.; Gunter, Marc J.; Keun, Hector C. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-05)
      Background. Endometrial cancer is strongly associated with obesity and dysregulation of metabolic factors such as estrogen and insulin signaling are causal risk factors for this malignancy. To identify additional novel metabolic pathways associated with endometrial cancer we performed metabolomic analyses on pre-diagnostic plasma samples from 853 case-control pairs from the European Prospective ...

    • Indirect acute effects of the COVID-19 pandemic on physical and mental health in the UK: a population-based study 

      Mansfield, Kathryn E; Mathur, Rohini; Tazare, John; Henderson, Alasdair D; Mulick, Amy R; Carreira, Helena; Matthews, Anthony A; Bidulka, Patrick; Gayle, Alicia; Forbes, Harriet; Cook, Sarah; Wong, Angel Y S; Strongman, Helen; Wing, Kevin; Warren-Gash, Charlotte; Cadogan, Sharon L; Smeeth, Liam; Hayes, Joseph F; Quint, Jennifer K; McKee, Martin; Langan, Sinéad M (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-18)
      Background There are concerns that the response to the COVID-19 pandemic in the UK might have worsened physical and mental health, and reduced use of health services. However, the scale of the problem is unquantified, impeding development of effective mitigations. We aimed to ascertain what has happened to general practice contacts for acute physical and mental health outcomes during the ...

    • Support and resources to promote and sustain health among nurses and midwives in the workplace: A qualitative study 

      Thapa, Dip Raj; Ekström-Bergström, Anette; Krettek, Alexandra; Areskoug Josefsson, Kristina (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-09)
      Registered nurses and midwives are in short supply and have among the highest rates of sick leave in the global workforce. The aim of this study was therefore to explore and gain a deeper understanding of how nurses and midwives experience their everyday work, with a view toward promoting and sustaining their work-related health. Nine registered nurses and four registered midwives working in hospitals ...

    • Phenotypic Characteristics and Melanoma Thickness in Women. 

      Ghiasvand, Reza; Green, Adele C.; Sandanger, Torkjel M; Weiderpass, Elisabete; Robsahm, Trude Eid; Veierød, Marit Bragelien (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-21)
      Patients’ phenotypic characteristics might be associated with melanoma aggressiveness, but the evidence is scarce. This study examined the associations be­tween pigmentary characteristics, naevi and melanoma thickness. Data from the Norwegian Women and Cancer (NOWAC) study were analysed. By 2014, 1,243 women were diagnosed with a primary melanoma, and 1,140 had information on thickness. Using ordinal ...

    • Strategies for Prevention and Treatment of COVID-19 related Symptoms. A Population Based Cross-sectional Study in Norway, Sweden and the Netherlands 

      Kristoffersen, Agnete Egilsdatter; Esther T., van der Werf; Stub, Trine; Musial, Frauke; Wider, Barbara; Jong, Miek; Danell, Jenny-Ann B.; Busch, Martine; Hoenders, H. J. Rogier; Nordberg, Johanna H.; Wode, Kathrin (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-23)
      Objectives: The present study was initiated to determine consultations with health care providers and use of selfmanagement strategies for prevention or treatment of COVID-19 related symptoms in countries with a full lockdown (Norway), a partial lockdown (the Netherlands) and no lockdown (Sweden) during the first three months of the COVID-19 pandemic, and if such use correlates with worries of being ...

    • PSMA Expression in Differentiated Thyroid Cancer: Association with Radioiodine, 18FDG Uptake, and Patient Outcome 

      Ciappuccini, Renaud; Saguet-Rysanek, Virginie; Giffard, Florence; Licaj, Idlir; Dorbeau, Marine; Clarisse, Bénédicte; Poulain, Laurent; Bardet, Stéphane (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-31)
      Context: Little is known about prostate-specific membrane antigen (PSMA) expression in patients with cervical involvement of differentiated thyroid cancer (DTC).<p> Objective: We investigated PSMA expression in neck persistent/recurrent disease (PRD) using immunohistochemistry and the association with radioiodine (RAI) or 18-fluorodeoxyglucose (<sup>18</sup>FDG) uptake, and patient outcome.<p> Design, ...

    • Evaluation of protein and amino acid intake estimates from the EPIC dietary questionnaires and 24-h dietary recalls using different food composition databases 

      Iguacel, Isabel; Perez-Cornago, Aurora; Schmidt, Julie A.; Van Puyvelde, Heleen; Travis, Ruth; Casagrande, Corinne; Nicolas, Genevieve; Riboli, Elio; Weiderpass, Elisabete; Ardanaz, Eva; Barricarte, Aurelio; Bodén, Stina; Bruno, Eleonora; Ching-López, Ana; Aune, Dagfinn; Jensen, Torill; Ericson, Ulrika; Johansson, Ingergerd; Ma Huerta, José; Katzke, Verena; Kühn, Tilman; Sacerdote, Carlotta; Schulze, Matthias B.; Skeie, Guri; Ramne, Stina; Ward, Heather; Gunter, Marc J.; Huybrechts, Inge (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-20)
      Background and aims: This study aimed to expand the European Prospective Investigation into Cancer and Nutrition (EPIC) nutrient database (ENDB) by adding amino acid (AA) values, using the U.S. nutrient database (USNDB). Additionally, we aimed to evaluate these new protein and AA intake estimates from the EPIC dietary questionnaires (DQ) and 24- h dietary recalls (24-HDR) using different matching ...