Effect of a low-carbohydrate diet on pain and quality of life in female patients with lipedema: a randomized controlled trial
Permanent lenke
https://hdl.handle.net/10037/35045Dato
2024-04-16Type
Journal articleTidsskriftartikkel
Peer reviewed
Forfatter
Lundanes, Julianne; Sandnes, Frida Huhta; Gjeilo, Kari Hanne; Salater, Sissel; Alho Letra Martins, Catia Patricia; Nymo, Siren; Hanson, PatrikSammendrag
Methods: Adult female patients with lipedema and obesity were randomized to either the LCD or control diet (energy prescription: 1200 kcal/day) for 8 weeks. Body weight and body composition, pain (Brief Pain Inventory measured pain), and QoL (RAND 36-Item Health Survey [RAND-36], Impact of Weight on Quality of Life [IWQOL]-Lite, and Lymphoedema Quality of Life [LYMQOL]) were measured at baseline and at postintervention.
Results: A total of 70 female patients (age, mean [SD], 47 [11] years; BMI 37 [5] kg/m2 ) were included. The LCD group had greater weight loss ( 2.8 kg; 95% CI: 4.1 to 1.0; p < 0.001) and larger reduction in pain now ( 1.1; 95% CI: 1.9 to 0.3; p = 0.009) compared with the control group. No association was found between changes in pain now and weight loss. Both groups experienced improvements in several QoL dimensions.
Conclusions: Diet-induced weight loss in women with lipedema can improve QoL. An energy-restricted LCD seems to be superior to a standard control diet in reducing pain.