Det helsevitenskapelige fakultet: Recent submissions
Now showing items 1-20 of 10396
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Inadequate nutritional care for malnourished patients in four university hospitals – The QuaNuT study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-01-30)Background & Aims: Adequate nutritional care to malnourished patients is described as a human right, and recommendations from nutritional care guidelines are legally binding in Norway. The primary objective of this study was to investigate nutritional care in malnourished hospitalized patients. We also wanted to describe the association between malnutrition and length of stay (LOS), readmission, ... -
Exploring public health nurses' acceptability of clinical assessment tools in a Norwegian child health centre
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-02-12)Background: Infants’ symptoms of mental struggle are often diffuse and undifferentiated, and health services do not identify many infants at risk of poor development. However, primary health care is advantageous for early identification, given there are frequent consultations during the infant’s first two years. Health policy encourages using evidence-based screening but use varies in primary ... -
Generative artificial intelligence to produce high-fidelity blastocyst-stage embryo images
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-04-10)STUDY QUESTION - Can generative artificial intelligence (AI) models produce high-fidelity images of human blastocysts?<p> <p>SUMMARY ANSWER - Generative AI models exhibit the capability to generate high-fidelity human blastocyst images, thereby providing substantial training datasets crucial for the development of robust AI models.<p> <p>WHAT IS KNOWN ALREADY - The integration of AI into IVF ... -
Randomized controlled trial of nasogastric tube use after esophagectomy: Study protocol for the kinetic trial
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-02-16)Esophagectomy is a complex and complication laden procedure. Despite centralization, variations in perioparative strategies reflect a paucity of evidence regarding optimal routines. The use of nasogastric (NG) tubes post esophagectomy is typically associated with significant discomfort for the patients. We hypothesize that immediate postoperative removal of the NG tube is non-inferior to current ... -
Data Resource Profile: The HUNT Biobank
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-06-04)<uli> <li>The Trøndelag Health Study (HUNT) Biobank, located at Levanger, Mid-Norway, holds biological material from 110 000 participants (aged 13–100 years) from the longitudinal population-based HUNT Study, Norway, including whole blood, serum, plasma, DNA, RNA, urine, saliva and fecal samples, optimally handled and stored for research purposes.</li> <li>Among 94 000 participants with ... -
Novel loss-of-function variants expand ABCC9-related intellectual disability and myopathy syndrome
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-01-13)Loss-of-function mutation of ABCC9, the gene encoding the SUR2 subunit of ATP sensitive-potassium (KATP) channels, was recently associated with autosomal recessive ABCC9-related intellectual disability and myopathy syndrome (AIMS). Here we identify nine additional subjects, from seven unrelated families, harbouring different homozygous loss-of-function variants in ABCC9 and presenting with a conserved ... -
Attitudes towards wife-beating justification and its association with female genital mutilation - analysis of ever-married Somali women in the 2020 Somali Health and Demographic Survey
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-06-17)Background - In Somalia, despite its prohibition, female circumcision persists alongside significant intimate partner violence. This study examines the prevalence of wife-beating justification among Somali women and its link to the perception that female genital mutilation/cutting (FGM/C) is a religious obligation.<p> <p>Methods - We studied 7726 married Somali women 15–49 y of age from the 2020 ... -
Needs for community-based rehabilitation services and support 12 months after moderate and severe physical traumatic injuries: a brief report
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-08)Patients with physical traumatic injuries frequently require long-term rehabilitation services. To strengthen rehabilitation services in the postacute phase, we need to assess characteristics of this population and their healthcare and rehabilitation needs in the community. This brief report summarizes the frequency of unmet rehabilitation needs in community-based rehabilitation during the first ... -
A histological study of the protracted dismantling of the spent (Sertoli-only) shark spermatocyst post-spermiation: Insight from species with or without testis-associated lymphomyeloid tissue
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-01-27)Sertoli cells of sharks are non-permanent components of the spermatocyst that they share exclusively with only one germ cell stage. After spermiation, all Sertoli cells, and thus the whole spent cyst, are disposed of in an area adjacent to the spermatozoal spermatocysts, that is, the resorption zone (RZ). Differences in the histology and magnitude of the RZ of the mature blue shark and Greenland ... -
The outcomes of team-based learning versus small group interactive learning in the obstetrics and gynecology course for undergraduate students
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-02-17)Introduction - Team-based learning (TBL) is a well-established active teaching method which has been shown to have pedagogical advantages in some areas such as business education and preclinical disciplines in undergraduate medical education. Increasingly, it has been adapted to clinical disciplines. However, its superiority over conventional learning methods used in clinical years of medical school ... -
FilmArray (BCID2) provides essential and timely results in bloodstream infections in small acute care hospitals without conventional microbiology services
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-01-12)We have evaluated the performance of FilmArray BCID2 in reactive blood cultures in a small acute care hospital compared to conventional diagnostics at a regional microbiological laboratory. This is a retrospective observational study of BactAlert reactive blood cultures (n = 160) from Helgeland Hospital, July–December 2021, analysed by BCID2 locally and conventional culture at a regional laboratory. ... -
Joint effect of ischemic stroke and obesity on the risk of venous thromboembolism: the Tromsø Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-03-27)Background: Patients with ischemic stroke have increased risk of venous thromboembolism (VTE). Obesity is prevalent in stroke patients and a well-established risk factor for VTE. Whether obesity further increases the VTE risk in patients with stroke remains unclear.<p> <p>Objectives: We investigated the joint effect of ischemic stroke and obesity on the risk of incident VTE in a population-based ... -
Major depression mistaken as frontotemporal dementia due to PET scan
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-04-02)Frontotemporal dementia (FTD) is associated with progressive degeneration of the frontal lobes and this leads to changes in language, motor symptoms, behavior and executive functions.1 In an early stage, patients with FTD usually have intact memory functions.2 40% of the cases of FTD are misdiagnosed,3 with delayed diagnosis compared to other dementias.4 Differentiating FTD from other psychiatric ... -
Would you like to be a general practitioner? Baseline findings of a longitudinal survey among Danish medical trainees
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-02-05)Background Recruiting and securing primary care physician workforce has been the center of international attention for decades. In Denmark, the number of general practitioners has decreased by 8.5% since 2013. However, a rising population age and increasing prevalence of chronic diseases and multimorbidity place an even greater future need for general practitioners in Denmark. The choice of ... -
Traditional Chinese medicine for post-viral olfactory dysfunction: A systematic review
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-04-25)Background: Post-viral olfactory dysfunction (PVOD) is the common symptoms of long COVID, lacking of effective treatments. Traditional Chinese medicine (TCM) is claimed to be effective in treating olfactory dysfunction, but the evidence has not yet been critically appraised. We conducted a systematic review to evaluate the effectiveness and safety of TCM for PVOD. Methods: We searched eight ... -
The sexual and reproductive healthcare challenges when dealing with female migrants and refugees in low and middle-income countries (a qualitative evidence synthesis)
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-02-19)Background Migrants and refugees face unprecedented inequalities in accessing sexual and reproductive health (SRH) in developed and developing countries. Most attention has focused on the rich world perspective, while there are huge numbers of migrants and refugees moving towards less developed countries. This article synthesizes the barriers to proper SRH care from low and middle-income ... -
Appetite and dietary intake endpoints in cancer cachexia clinical trials: Systematic Review 2 of the cachexia endpoints series
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-02-11)There is no consensus on the optimal endpoint(s) in cancer cachexia trials. Endpoint variation is an obstacle when compar ing interventions and their clinical value. The aim of this systematic review was to summarize and evaluate endpoints used to assess appetite and dietary intake in cancer cachexia clinical trials. A search for studies published from 1 January 1990 until 2 June 2021 was conducted ... -
Treatment and prevention of neonatal sepsis
(Doctoral thesis; Doktorgradsavhandling, 2024-09-20)Worldwide, the incidence of neonatal sepsis is estimated at around 3000 cases per 100,000 live births, accompanied by a mortality rate of 17.6%. Group B streptococcus (GBS) is globally the leading cause of newborn infections. The global burden of neonatal sepsis and invasive GBS disease is skewed towards the low-income countries, but the outcome of invasive GBS disease with massive inflammation can ... -
Adhesion mechanisms and bacteriocins in Staphylococcus haemolyticus - New targets for the prevention and treatment of infections
(Doctoral thesis; Doktorgradsavhandling, 2024-09-13)<i>Staphylococcus haemolyticus</i> er ein bakterie med mange eigenskapar. Han finst naturleg i mikrobiotaen vår, men kan også vere opportunistisk patogen. Evna til å danne biofilm, unngå immunsystemet og motstå antibiotikabehandling gjer at behandling er utfordrande. Målet med avhandlinga var å utvide forståinga av virulensfaktorar og bakteriosinproduksjon hos bakterien for å finne betre måtar å ... -
An evidence map on traditional medicine across health outcomes
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-07-25)Background - Traditional medicine (TM) plays a significant role in healthcare either as part of the primary healthcare system or as an adjunct to conventional medicine. This study aimed to map systematic reviews (SRs) of TM modalities across health conditions and identify gaps in the research literature to facilitate priority setting in future TM research.<p> <p>Methods - We searched 17 databases ...