Det helsevitenskapelige fakultet: Recent submissions

Now showing items 1-20 of 10152

    • The effect of β-lactamase evolution on biofilm formation in Vibrio cholerae 

      Haukefer, Anne Sofie Bernhardsen (Master thesis; Mastergradsoppgave, 2023-05-15)
      Antimicrobial resistance (AMR) has emerged as one of the greatest threats to public health in the 21st century. Especially, the production of -lactamase enzymes has become the leading cause of -lactam resistance in Gram-negative pathogens. In addition, many of the pathogens associated with extensive antimicrobial resistance form biofilms, which further increases their persistence. Studies from ...

    • Kvalitet av legemiddelbruk og legemiddelinformasjon hos hoftebruddspasienter ved Sykehuset i Vestfold HF – en tverrsnittstudie 

      Nguyen, Caroline Thy (Master thesis; Mastergradsoppgave, 2019-05-15)
      Det er i hovedsak eldre personer som gjennomgår hoftebrudd, som er et fryktet osteoporotisk brudd. Eldre har flere sykdommer som fører til at de blir behandlet med flere legemidler sammenlignet med yngre. Dette vil igjen øke risikoen for uhensiktsmessig legemiddelbruk. I tillegg overføres eldre hyppig inn og ut og mellom helseinstitusjoner, som skaper et behov for velfungerende informasjonsoverføring. ...

    • The Association between the Energy-adjusted Dietary Inflammatory Index and the Risk of Colorectal Cancer in The Norwegian Women and Cancer Study (NOWAC) 

      Berg, Anna Emilie Vinje (Mastergradsoppgave; Master thesis, 2023-05-15)
      Background: Colorectal cancer (CRC) is one of the most common cancer types and a leading cause of cancer death worldwide. Norwegian women had the highest incidence rate in 2020 compared to women in other countries. Existing evidence suggests that the dietary inflammatory potential is associated with the risk of CRC and that the risk may vary by anatomical subsite. However, the findings are inconsistent ...

    • The Relationship between Psychological Factors and Performance Level in Female Football 

      Fredriksen, Sveinung Nordhov (Master thesis; Mastergradsoppgave, 2023-05-15)
      The purpose of this study was to see if there were significant differences in female football players' psychological factors across performance levels. We also investigated whether the same differences could predict at what level female football players compete. Method: The study involved a sample of 188 female football players across three performance levels. Data were collected by five questionnaires, ...

    • Associations between intake of dairy products and colorectal lesions in the Norwegian CRCbiome study: a cross-sectional study 

      Grønvik, Frøya Berg (Mastergradsoppgave; Master thesis, 2023-05-15)
      Background: Intake of dairy is associated with lower risk of CRC. It is, however, unclear whether this risk reduction applies to all types of dairy products and whether it also applies to precancerous lesions. Aim/objective: To examine the association between intake of dairy products and CRC screening findings (non-advanced lesions and advanced colorectal lesions (ACN)) in participants with a ...

    • Plasma von Willebrand factor and risk of future venous thromboembolism 

      Edvardsen, Magnus Sandvik (Doctoral thesis; Doktorgradsavhandling, 2024-05-31)
      Venous thromboembolism (VTE), an umbrella term for deep vein thrombosis (DVT) and pulmonary embolism (PE), is a common disease with serious complications. Meanwhile, the exact underlying mechanisms remain unclear. Von Willebrand factor (VWF) is pivotal in haemostasis, and likely causally involved in VTE. VWF is regulated by ADAMTS13 and can promote haemostasis in two distinct ways; i.e., interaction ...

    • Helseattest for kvinnelige langrennsløpere – trenernes erfaringer 

      Landsem, Lone Lovise (Master thesis; Mastergradsoppgave, 2022-05-13)
      I 2014 resulterte et samarbeid mellom Sunn Idrett og Olympiatoppen til innføring av en ordning med helseattest. Ordningens mål er å sette helsen til toppidrettsutøvere i norsk friidrett, orientering, langrenn og skiskyting foran prestasjon. Dersom helseattesten avdekker uheldige forhold vedrørende en utøvers helse, kan utøveren få «startnekt» i internasjonale konkurranser. Formålet med denne oppgaven ...

    • Sikkerhet og beslutningstaking i profesjonsrettet friluftsliv 

      Tilley, Christine (Master thesis; Mastergradsoppgave, 2023-05-13)
      Denne masteroppgaven i idrettsvitenskap ved Universitet i Tromsø tar utgangspunkt i fagfeltet friluftsliv og temaet sikkerhet og beslutninger i profesjonsrettet friluftsliv. Studiens problemstilling undersøker betydningen av erfaring og overskudd samt strategier for ivaretakelse av overskudd for turledere på Svalbard. Problemstillingen undersøkes gjennom kvalitative forskningsintervju av 5 erfarne ...

    • Dual delivery of chlorogenic acid and mimic of antimicrobial peptide – towards wound treatment 

      Salamonsen, Mari (Master thesis; Mastergradsoppgave, 2022-05-12)
      Chronic wounds are a major burden, causing both morbidity and mortality in patients, as well as a massive economical strain on health care systems worldwide. These wounds have a high degree of complexity and are often difficult to treat due to the many factors limiting healing, such as inflammation, biofilm formation and bacterial infections. With these typically persistent infections and a rising ...

    • Chitosan-modified liposomes for delivery of membrane-active antimicrobials – exploring the role of the polymer 

      Panchai, Pimmat (Master thesis; Mastergradsoppgave, 2022-05-12)
      Antimicrobial resistance in skin injury infections is becoming a rising problem as more conventional antimicrobials become ineffective in resistant infections. Therefore, developing novel effective antimicrobials while promoting wound healing is urgently needed. Membrane-active antimicrobials, such as antimicrobial peptides (AMPs), display promising antimicrobial activity, and could potentially solve ...

    • Hvilken innvirkning hadde restriksjonene forbindelse med Covid-19 pandemien på eldres mentale helse og sosiale relasjoner? – en litteraturstudie med systematisk tilnærming 

      Johansen, Siw-Renate (Master thesis; Mastergradsoppgave, 2022-05-04)
      <p>Bakgrunn:. Mars 2020 ble verden rammet av en epidemi, Covid-19 pandemien førte til at en rekke land stengte ned og eldre ble bedt om å holde seg innendørs og unngå kontakt med andre, for å beskytte seg mot alvorlig sykdom og død. <p>Hensikt: Hensikten med denne oppgaven var å granske og sammenstille tidligere forskning som har sett på hvordan isolasjon og ensomhet under Covid-19 pandemien har ...

    • Characterization of competition between commensal A2 and clinical A1 strains of Enterococcus faecium 

      Fenzel, Carolin Kornelia (Mastergradsoppgave; Master thesis, 2023-05-14)
      Enterococcus faecium (E. faecium) emerged from a gut commensal to one of the leading nosocomial multidrug-resistant pathogens. The species of E. faecium, has a deep phylogenetic split into commensal and clinical strains. The dominance of clinical strains during nosocomial infections is only insufficiently understood. Previous studies revealed competitive characteristics between the commensal ...

    • Exploring the adenosine system by cancer-associated fibroblasts in the context of radiotherapy 

      Afroj, Shamima (Mastergradsoppgave; Master thesis, 2023-05-14)
      Background of the study: Cancer-associated fibroblasts (CAFs) are a heterogeneous population of cells that are mainly found in solid malignancies and play vital roles in tumor progression and metastasis, including important immunoregulatory functions. In this study, our objective was to explore the immunosuppressive adenosine system within the CAFs isolated from non-small cell lung carcinomas (NSCLC) ...

    • Using High-Resolution Mass Spectrometry to identify lipids in marine bacterial biomass 

      Laugsand, Gøril (Mastergradsoppgave; Master thesis, 2023-05-14)
      Background: BMFishfeed is a cooperative project since 2021 between UiT the Arctic University of Norway, NORCE Stavanger and the University of South-Eastern Norway where the goal is to develop a lipid-rich bacterial meal that can be utilized as fish feed in the aquaculture industry. Carbon-rich waste from an omega-3 production site is used as nutrition for marine bacterial cultures, which are fermented ...

    • Default, time-pressured and incentivized deliberate reasoning 

      Abukar, Fozia Aweys (Mastergradsoppgave; Master thesis, 2021-05-14)
      The purpose of this study was to investigate the effect time-pressure and incentives have on deliberate reasoning. A person’s tendency to engage in and enjoy processes that require reasoning, i.e., their need for cognition, and their algorithmic ability are factors that may moderate performance in reasoning tasks when they are under time-pressure or given monetary reward. Identifying how to increase ...

    • Effect of ketosis on pain and quality of life in women with lipedema. 

      Sandnes, Frida Huhta (Mastergradsoppgave; Master thesis, 2022-05-13)
      Background: Lipedema is an adipose tissue condition in females characterized by immobility, pain, and reduced quality of life (QoL). Recent publications indicate that ketogenic diets may induce symptom relief in women with lipedema. The aim of this study was to investigate the impact of a low-energy ketogenic diet on pain and QoL in women with lipedema, compared to a low-energy non-ketogenic ...

    • Process optimization of albumin-stabilized mitotane nanoparticle preparation by dual centrifugation and first lyophilization study 

      Zhang, Cindy Jia Ru (Mastergradsoppgave; Master thesis, 2022-05-13)
      Albumin-stabilized mitotane nanoparticles intended for intravenous application can serve as a potential formulation for the treatment of adrenocortical carcinoma. However, the particle size of a nanoparticle-based formulation is crucial for the in vivo behavior of the nanoparticles following an intravenous injection. Prior to this project, the particle size of this nanoformulation had a mean of ...

    • Mapping the Well-Being of Norwegian Mothers During the COVID-19 Pandemic 

      Kvalø, Marie (Mastergradsoppgave; Master thesis, 2022-05-12)
      The COVID-19 pandemic has had negative effects on people’s well-being and quality of life. In order to extend existing research, we focused on Norwegian mothers with children in elementary schools, and investigated whether the pandemic influenced their well-being, stress, and worries. Our sample consisted of 231 mothers responding in the first data collection that took place June 2020, 97 mothers ...

    • Push and pull factors for migration of foreign pharmacists to Norway 

      Iqbal, Saleem (Mastergradsoppgave; Master thesis, 2022-05-12)
      Migration of foreign pharmacists to Norway has increased considerably in recent years. Data from the Directorate of Health shows that 1592 foreign pharmacists received authorization in Norway from 2013 to 2021 as compared to 1952 Norwegian pharmacists. There are several theories of migration, but “push and pull theory” is the most widely used approach to learn about reasons of migration. According ...

    • Computational studies on the human GnRH-I and the GnRH-receptor 

      Tran, Anton (Mastergradsoppgave; Master thesis, 2022-05-12)
      Gonadotropin-releasing hormone receptor (GnRH-R), which is a Class A G-protein coupled receptor (GPCR), has a vital role in the regulation of sex hormones. The receptor also has a prominent role in diseases, with examples being reproductive cancers and non-reproductive cancers like glioblastoma. Gonadotropin-releasing hormone (GnRH) agonists have been proven to combat cell proliferation in cancers. ...