Now showing items 1121-1140 of 10404

    • Selvrapportert psykisk helse, ensomhet og sosial støtte blant innbyggere i Tromsø kommune, i grupper av kjønn, alder og sosioøkonomisk status: En del av Fylkeshelseundersøkelsen i Troms og Finnmark 2019 

      Endresen, Hege (Mastergradsoppgave; Master thesis, 2023-08-01)
      Rationale for studie: Tromsø kommune har behov for et kunnskapsgrunnlag i sitt folkehelsearbeid. Det er spesielt viktig å undersøke grad av psykisk uhelse, ensomhet og sosial støtte i ulike grupper i befolkningen, da tidligere studier har vist forskjeller mellom kjønn, alders- og utdanningsgrupper. Eksisterende datakilder, som inkluderer folkehelserapporter fra Tromsøundersøkelsen og FHI’s ...
    • LIS1-leger og medisinsk usikkerhet – en kvalitativ studie 

      Ofstad, Eirik Hugaas; Asdal, Karoline; Nightingale, Bruno; Han, Paul K.; Gregersen, Trine Ammentorp; Gulbrandsen, Pål (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-29)
      BAKGRUNN - Hvordan norske leger håndterer medisinsk usikkerhet, er lite studert. Formålet med studien var å undersøke hvordan leger i spesialisering del 1 (LIS1-leger) opplever og håndterer usikkerhet i en klinisk hverdag.<p> <p>MATERIALE OG METODER - Ti LIS1-leger ved to sykehus ble rekruttert til intervjuer etter svarmønsteranalyse fra et kartleggende spørreskjema. Intervjuene ble analysert ...
    • Midwives and public health nurses' knowledge and clinical practice in securing sufficient iodine status in relation to pregnancy. A cross-sectional study 

      Johnsen, Maren; Braaten, Tonje Bjørndal; Skeie, Guri; Laholt, Hilde; Hansen, Solrunn (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-25)
      Aim - To investigate midwives' (MWs) and public health nurses' (PHNs) clinical practice and knowledge related to nutrition, with a particular focus on iodine in northern parts of Norway. Maternal iodine status prior to and during pregnancy, and the lactating period, is crucial for brain development and growth of the foetus and infant, from conception up until the first two years of life. In Norway, ...
    • The expression pattern of pyruvate dehydrogenase kinases predicts prognosis and correlates with immune exhaustion in clear cell renal cell carcinoma 

      Nunes-Xavier, Caroline Elisabeth; Emaldi, Maite; Mingo, Janire; Øyjord, Tove Ragnhild; Mælandsmo, Gunhild Mari; Fodstad, Øystein; Errarte, Peio; Larrinaga, Gorka; Llarena, Roberto; López, José I.; Pulido, Rafael (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-05)
      Renal cancer cells constitute a paradigm of tumor cells with a glycolytic reprogramming which drives metabolic alterations favouring cell survival and transformation. We studied the expression and activity of pyruvate dehydrogenase kinases (PDK1-4), key enzymes of the energy metabolism, in renal cancer cells. We analysed the expression, subcellular distribution and clinicopathological correlations ...
    • Gut microbiota composition during hospitalization is associated with 60-day mortality after severe COVID-19 

      Trøseid, Marius; Holter, Jan Cato; Holm, Kristian; Vestad, Beate; Sazonova, Taisiia; Granerud, Beathe Kiland; Dyrhol-Riise, Anne Ma; Holten, Aleksander Rygh; Tonby, Kristian; Kildal, Anders Benjamin; Heggelund, Lars; Tveita, Anders Aune; Bøe, Simen; Müller, Karl Erik; Jenum, Synne; Hov, Johannes Espolin Roksund; Ueland, Thor (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-23)
      Background - Gut microbiota alterations have been reported in hospitalized COVID-19 patients, with reduced alpha diversity and altered microbiota composition related to respiratory failure. However, data regarding gut microbiota and mortality are scarce.<p> <p>Methods - Rectal swabs for gut microbiota analyses were collected within 48 h after hospital admission (baseline; n = 123) and three-month ...
    • Development of Hypertension and Diabetes Mellitus, and Associated Factors, Among Adult HIV Patients in Ethiopia 

      Tegene, Yadessa; Mengesha, Selamawit; Putman, Erin; Toma, Alemayehu; Spigt, Marcus (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-16)
      Background: Medical improvements and increased access to treatment have turned HIV from a highly fatal disease into a treatable and controllable disease. With the improvement in lifespan, HIV patients face increasing morbidity and mortality from chronic comorbidities (hypertension and diabetes mellitus). There is, nevertheless, a paucity of information on the scale of HIV noncommunicable disease ...
    • Does method matter? Assessing the validity and clinical utility of structured diagnostic interviews among a clinical sample of first-admitted patients with psychosis: A replication study 

      Kvig, Erling Inge; Nilssen, Steinar (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-04-03)
      Introduction: Increasingly, diagnostic assessments in clinical practice are made using structured diagnostic interviews or self-rating scales imported into clinical practice from research studies and big-scale surveys. Although structured diagnostic interviews have been shown to be highly reliable in research, the use of such method in clinical contexts are more questionable. In fact the validity ...
    • VTE epidemiology and challenges for VTE prevention at the population level: VTE epidemiology 

      Brækkan, Sigrid Kufaas; Hansen, John Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-17)
      Venous thromboembolism (VTE) is a frequent disease affecting more than 1 in 12 individuals during their lifetime. VTE is associated with a substantial disease burden due to long-term complications such as recurrence, the post-thrombotic syndrome, and the post-pulmonary embolism syndrome. Despite the knowledge of several risk factors and triggers, more than one third of the VTE events occur in the ...
    • Filling the Void: The Role of Adult Siblings Caring for a Brother or Sister With Severe Mental Illness 

      Kitzmüller, Gabriele; Wiklund Gustin, Lena; Kalhovde, Anne Martha (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-30)
      Little is known about the role of adult siblings’ caregiver role within the context of mental illness. Therefore, our purpose was to explore how siblings narrate their experiences of being the main caregivers of a brother or sister with severe mental illness and how they cooperate with their ill sibling and their family of origin. We used a narrative hermeneutic approach and performed a secondary ...
    • How do public health nurses in Norwegian school health services support siblings of children with complex care needs? 

      Bergvoll, Lise-Marie; Fjelldal, Sunniva Solhaug; Clancy, Anne Mary Gerard; Martinussen, Monica; Laholt, Hilde (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-29)
      Aims: There is a paucity of data regarding the care and support provided by Norwegian school health services to siblings of children with complex care needs. Public health nurses are an integral part of these universal services, which focus on health promotion and disease prevention in primary and secondary schools. This study aimed to explore health promotion interventions by public health ...
    • Procurement of artificial intelligence for radiology practice 

      Silsand, Line; Severinsen, Gro-Hilde; Linstad, Line Helen; Ellingsen, Gunnar (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-22)
      The development of artificial intelligence (AI) technology for radiology has accelerated in the past decade, but its deployment in radiology practices has been slow. We take a sociotechnical approach and suggest that the limited use of AI in radiology practices can be attributed to a recurring tension between planned and emergent change. The paper contributes with a conceptualization and understanding ...
    • Comparing the sociodemographic characteristics of participants and non-participants in the population-based Tromsø Study 

      Vo, Chi Quynh; Samuelsen, Per-Jostein; Sommerseth, Hilde Leikny; Wisløff, Torbjørn; Wilsgaard, Tom; Eggen, Anne Elise (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-29)
      Background Diferences in the sociodemographic characteristics of participants and non-participants in populationbased studies may introduce bias and reduce the generalizability of research fndings. This study aimed to compare the sociodemographic characteristics of participants and non-participants of the seventh survey of the Tromsø Study (Tromsø7, 2015–16), a population-based health survey.<p> ...
    • Sputum bacterial load and bacterial composition correlate with lung function and are altered by long-term azithromycin treatment in children with HIV-associated chronic lung disease 

      Abotsi, Regina E.; Dube, Felix S.; Rehman, Andrea M.; Claassen-Weitz, Shantelle; Xia, Yao; Simms, Victoria; Mwaikono, Kilaza S.; Gardner-Lubbe, Sugnet; McHugh, Grace; Ngwira, Lucky G.; Kwambana-Adams, Brenda; Heyderman, Robert S.; Odland, Jon Øyvind; Ferrand, Rashida A.; Nicol, Mark P. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-20)
      Background - Long-term azithromycin (AZM) treatment reduces the frequency of acute respiratory exacerbation in children and adolescents with HIV-associated chronic lung disease (HCLD). However, the impact of this treatment on the respiratory bacteriome is unknown.<p> <p>Method - African children with HCLD (defined as forced expiratory volume in 1 s z-score (FEV1z) less than − 1.0 with no ...
    • Early diagnosis and better rhythm management to improve outcomes in patients with atrial fibrillation: the 8th AFNET/EHRA consensus conference 

      Schnabel, Renate B; Marinelli, Elena Andreassi; Arbelo, Elena; Boriani, Giuseppe; Boveda, Serge; Buckley, Claire M; Camm, A. John; Casadei, Barbara; Chua, Winnie; Dagres, Nikolaos; De Melis, Mirko; Desteghe, Lien; Diederichsen, Søren Zöga; Duncker, David; Eckardt, Lars; Eisert, Christoph; Engler, Daniel; Fabritz, Larissa; Freedman, Ben; Gillet, Ludovic; Goette, Andreas; Guasch, Eduard; Svendsen, Jesper Hastrup; Hatem, Stphane N; Haeusler, Karl Georg; Healey, Jeff S; Heidbuchel, Hein; Hindricks, Gerhard; Hobbs, F. D. Richard; Hübner, Thomas; Kotecha, Dipak; Krekler, Michael; Leclercq, Christophe; Lewalter, Thorsten; Lin, Honghuang; Linz, Dominik; Lip, Gregory Y. H.; Løchen, Maja-Lisa; Lucassen, Wim; Malaczynska-Rajpold, Katarzyna; Massberg, Steffen; Merino, Jose L; Meyer, Ralf; Mont, Lluls; Myers, Michael C; Neubeck, Lis; Niiranen, Teemu; Oeff, Michael; Oldgren, Jonas; Potpara, Tatjana S; Psaroudakis, George; Pürerfellner, Helmut; Ravens, Ursula; Rienstra, Michiel; Rivard, Lena; Scherr, Daniel; Schotten, Ulrich; Shah, Dipen; Sinner, Moritz F; Smolnik, Rüdiger; Steinbeck, Gerhard; Steven, Daniel; Svennberg, Emma; Thomas, Dierk; True Hills, Mellanie; Van Gelder, Isabelle C; Vardar, Burcu; Palà, Elena; Wakili, Reza; Wegscheider, Karl; Wieloch, Mattias; Willems, Stephan; Witt, Henning; Ziegler, Andrd; Daniel Zink, Matthias; Kirchhof, Paulus (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-27)
      Despite marked progress in the management of atrial fibrillation (AF), detecting AF remains difficult and AF-related complications cause unacceptable morbidity and mortality even on optimal current therapy. This document summarizes the key outcomes of the 8th AFNET/EHRA Consensus Conference of the Atrial Fibrillation NETwork (AFNET) and the European Heart Rhythm Association (EHRA). Eighty-three ...
    • The child's place in the foster family: Use of conventional names and adoption intentions throughout childhood 

      Kaiser, Sabine; Mabille, Geraldine; Thørnblad, Renee; Skoglund, Jeanette (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-08-13)
      This longitudinal study examines the child's place in the foster family through the use of conventional names for familial figures (e.g., ‘mum/dad’) and through the foster parents' intention to adopt the child. Data were collected at two time points during childhood and adolescence, among children placed in kinship and non-kinship foster care in Norway. Children placed at a younger age and children ...
    • Autoimmune disease and risk of postpartum venous thromboembolism 

      Walker, Rob F.; Zakai, Neil A.; Mason, Susan M.; MacLehose, Richard F.; Norby, Faye L.; Evensen, Line Holtet; Alonso, Alvaro; Lutsey, Pamela L. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-23)
      Background - The risk of pregnancy-related mortality in the United States has nearly doubled since 1990, with venous thromboembolism (VTE) accounting for approximately 10% of these deaths.<p> <p>Objectives - The objective of this study was to assess whether preexisting autoimmune disease is a risk factor for postpartum VTE.<p> <p>Methods - Using the MarketScan Commercial and Medicare Supplemental ...
    • What Drives Animal Fluency Performance in Cantonese-Speaking Chinese Patients with Adult-Onset Psychosis? 

      Hui, Christy Lai-Ming; See, Sally Hiu-Wah; Chiu, Tsz-Ching; Pintos, Andrea Stephanie; Kroyer, Johanna M.; Suen, Yi-Nam; Lee, Edwin Ho-Ming; Chan, Sherry Kit-Wa; Chang, Wing-Chung; Elvevåg, Brita; Chen, Eric Yu-Hai (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-27)
      Among the numerous studies investigating semantic factors associated with functioning in psychotic patients, most have been conducted on western populations. By contrast, the current cross-sectional study involved native Cantonese-speaking Chinese participants. Using the category fluency task, we compared performance between patients and healthy participants and examined clinical and sociodemographic ...
    • Taking hospital pathogen surveillance to the next level 

      Werner, Guido; Couto, Natacha; Feil, Edward J.; Novais, Angela; Hegstad, Kristin; Howden, Benjamin P.; Friedrich, Alexander W.; Reuter, Sandra (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-04-26)
      High-throughput bacterial genomic sequencing and subsequent analyses can produce large volumes of high-quality data rapidly. Advances in sequencing technology, with commensurate developments in bioinformatics, have increased the speed and efficiency with which it is possible to apply genomics to outbreak analysis and broader public health surveillance. This approach has been focused on targeted ...
    • Etablering av medisinske sannheter 

      Alstadhaug, Karl Bjørnar; Aamodt, Anne Hege (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-27)
    • Methylation-regulated long non-coding RNA expression in ulcerative colitis 

      Fenton, Christopher Graham; Ray, Mithlesh Kumar; Meng, Wei; Paulssen, Ruth H (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-22)
      Long non-coding RNAs (lncRNAs) have been shown to play a role in the pathogenesis of ulcerative colitis (UC). Although epigenetic processes such as DNA methylation and lncRNA expression are well studied in UC, the importance of the interplay between the two processes has not yet been fully explored. It is, therefore, believed that interactions between environmental factors and epigenetics ...