Det helsevitenskapelige fakultet: Recent submissions
Now showing items 1581-1600 of 10407
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The Sexual Incentive Motivation Model and Its Clinical Applications
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-15)Sexual motivation (desire) requires the simultaneous presence of an active central motive state and a stimulus with sexual significance. Once activated, sexual motivation leads to visceral responses and approach behaviors directed toward the emitter of the sexual stimulus. In humans, such behaviors follow cognitive evaluation of the context, including predictions of the approached individual’s ... -
A Systematic Review and Meta-Analysis of Measurement Feedback Systems in Treatment for Common Mental Health Disorders
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-25)To investigate the efects of measurement feedback systems (MFSs) in therapy on mental health outcomes through a literature review and meta-analysis. Using a three-level modeling approach, we conducted a meta-analysis of all efect sizes from randomized controlled studies of MFSs used in the treatment of common mental health disorders. Eighty-two efect sizes were extracted from the thirty-one included ... -
Age, income and sleep duration were associated with outcomes in children participating in weight management
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-23)Aim To explore associations between baseline factors and weight-related outcomes among participants enrolled in a paediatric obesity trial. Methods We included children aged 6–12 years participating in a 2-year multidisciplinary family programme who attended a postintervention follow-up 36 months from baseline (n = 62). Outcome measures were change in body mass index standard deviation score (BMI ... -
Mercury, silver and selenium in serum before and after removal of amalgam restorations: results from a prospective cohort study in Norway
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-16)<p><b> Objective</b> A prospective cohort study on changes of health complaints after removal of amalgam restorations was carried out at the request of the Norwegian Directorate of Health. The aim was to provide and evaluate experimental treatment to patients with health complaints attributed to dental amalgam fillings. <p><b> Methods</b> Patients (n = 32) with medically unexplained ... -
Reproductive changes among women in their 40s: A cross-sectional study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-05)Introduction The aim was to describe and compare changes in the reproductive pattern of women in their 40s observed over a decade in Scandinavia. Material and Methods Cross-sectional study using the total population of women aged 40–49 years between 2008–2018 in Denmark, Norway and Sweden (on average n = 1.5 million). Aggregated data concerning birth and induced abortion rate were collected and ... -
The impact of implementing patient-reported measures in routine maternity care: a systematic review
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-05)Introduction While there is growing interest in applying patient-reported measures (PRMs) in clinical routine, limited collective evidence of the impact of PRMs hinder their widespread use in specific contexts, such as maternity care. Our objective was to synthesize existing emperical evidence on the impact of implementing PRMs in routine maternity care. Material and methods We followed the ... -
Validity and responsiveness of GHC-index in patients with amalgam-attributed health complaints
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-15)<p><b> Objective</b> Many patients have medically unexplained physical symptoms (MUPS); some of them attribute their health complaints to dental amalgam fillings. The aim of this study was to assess the validity and responsiveness of General Health Complaints index (GHC-index) for measuring the symptom load in MUPS patients compared to the widely used symptom outcome measure, Giessen Subjective ... -
Leger utdannet i Bodø – hvem er de og hvor blir de av?
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-10)<p><b> BAKGRUNN</b> Siden 2009 har inntil 24 legestudenter ved Universitetet i Tromsø årlig fullført de to siste årene av utdanningen i Bodø (kalt Bodøpakken). Vi kartla oppvekstkommune, ønsker for framtidig spesialitet blant studentene og hvor og hva studentene arbeidet med etter LIS1-tjenesten. <p><b> MATERIALE OG METODE</b> Legestudenter uteksaminert i Bodø i perioden 2012–18 fikk et ... -
External Validation of the Graded Prognostic Assessment in Patients with Brain Metastases from Small Cell Lung Cancer
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-29)Background: Recently, graded prognostic assessment (GPA) for small cell lung cancer (SCLC) patients with brain metastases has been developed. This includes age, performance status, number of brain metastases and presence of extracranial metastases. The aim of the present study was to validate this four-tiered prognostic score in a European cohort of patients. Methods: The retrospective validation ... -
Eating and speech problems in oral and pharyngeal cancer survivors – Associations with treatment-related side-effects and time since diagnosis
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-18)Aims: The aim of this cross-sectional study was to find factors associated with problems with the ability to eat and speak in oral and pharyngeal cancer (OPC) survivors and to evaluate if the panorama of oral problems varied with time since diagnosis.<p> <p>Methods and Results: A questionnaire assessing cancer diagnosis and treatment, oral health-related quality of life, and presence of ... -
Epidemiology and natural history in 101 subjects with FKRP-related limb-girdle muscular dystrophy R9. The Norwegian LGMDR9 cohort study (2020)
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-25)We aimed to investigate the epidemiology and natural history of FKRP-related limb-girdle muscular dystrophy R9 (LGMDR9) in Norway. We identified 153 genetically confirmed subjects making the overall prevalence 2.84/100,000, the highest reported figure worldwide. Of the 153 subjects, 134 (88 %) were homozygous for FKRP c.826C>A giving a carrier frequency for this variant of 1/101 in Norway. Clinical ... -
The burden of colon cancer attributable to modifiable factors—The Norwegian Women and Cancer Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-22)Colon cancer is the second most frequently diagnosed cancer in women in Norway, where incidence rates of colon cancer increased 3-fold between 1955 and 2014, for unknown reasons. We aimed to assess the burden of colon cancer attributable to modifiable risk factors in Norwegian women using the data from the Norwegian Women and Cancer (NOWAC) study. Self-reported information from 35 525 women from the ... -
Trøstens stille stemme i helsesykepleiekonsultasjoner
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-13)Å gi trøst er en integrert del av sykepleie, og å få trøst er et grunnleggende menneskelig behov. I dette vitenskapelige essayet ser vi nærmere på hvordan fenomenet trøst kommer til uttrykk i norsk helsesykepleiepraksis. Helsesykepleiere i Norge yter ikke pleietjenester, men tilbyr helsefremmende og forebyggende helsetjenester til barn og unge mellom 0 og 20 år. Deres omsorgspraksis har blitt beskrevet ... -
Experimental long-distance haplotyping of OCA2-HERC2 variants
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-18)The regulatory HERC2 SNP, rs12913832, is strongly associated with blue and brown eye colour. However, eye colour in heterozygous rs12913832 individuals is observed to vary greatly. Missense mutations in OCA2, such as rs1800407 and rs74653330, are associated with lighter eye colour in some but not all heterozygous rs12913832 individuals. Determining the physical linkage of these variants might ... -
Quality of health care around the time of childbirth during the COVID-19 pandemic: Results from the IMAgiNE EURO study in Norway and trends over time
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-18)Objective: To describe maternal perception of the quality of maternal and newborn care (QMNC) in facilities in Norway during the first year of COVID-19 pandemic.<p> <p>Methods: Women who gave birth in a Norwegian facility from March 1, 2020, to October 28, 2021, filled out a structured online questionnaire based on 40 WHO standards-based quality measures. Quantile regression analysis was performed ... -
Modelling fatty liver disease with mouse liver-derived multicellular spheroids
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-28)Chronic liver disease can lead to liver fibrosis and ultimately cirrhosis, which is a significant health burden and a major cause of death worldwide. Reliable in vitro models are lacking and thus mono-cultures of cell lines are still used to study liver disease and evaluate candidate anti-fibrotic drugs. We established functional multicellular liver spheroid (MCLS) cultures using primary mouse ... -
First-time parents' experiences related to parental self-efficacy: A scoping review
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-23)Becoming a parent for the first time is a major transition, and parental self‐efficacy (PSE) is considered an important predictor of parenting functioning. We aimed to describe and synthesize qualitative studies that explore first‐time parents' experiences related to PSE in the transition to parenthood in the first‐year postpartum. We conducted a scoping review in accordance with international ... -
Magnetic resonance imaging for non-invasive measurement of plastic ingestion in marine wildlife
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-17)Monitoring plastic ingestion by marine wildlife is important for both characterizing the extent of plastic pollution in the environment and understanding its effect on species and ecosystems. Current methods to detect plastic in the digestive system of animals are slow and invasive, such that the number of animals that can be screened is limited. In this article, magnetic resonance imaging (MRI) ... -
Hvordan trøster du spedbarnet ditt? Et spenningsfelt mellom intuitiv adferd, kultur og kunnskap
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-13)Dette essayet omhandler spedbarnstrøst. Hvorfor trøst er så betydningsfullt for spedbarnet, og hvordan omsorgspersoners kapasitet til å trøste påvirkes av intuitiv adferd, kultur og nyere forskning og erfaringsbasert kunnskap. Trøst i denne livsfasen er innspunnet i grunnleggende omsorg, og barnet behøver hyppig støtte til å dempe uhensiktsmessig aktivitet i et umodent nervesystem. Det essensielle ... -
Assessment of the EarlyCDT-Lung test as an early biomarker of lung cancer in ever-smokers: A retrospective nested case-control study in two prospective cohorts
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-28)The EarlyCDT-Lung test is a blood-based autoantibody assay intended to identify high-risk individuals for low-dose computed tomography lung cancer screening. However, there is a paucity of evidence on the performance of the EarlyCDT-Lung test in ever-smokers. We conducted a nested case-control study within two prospective cohorts to evaluate the risk-discriminatory performance of the EarlyCDT-Lung ...