Mental health surveys of general populations use psychometric instruments derived from psychiatric symptom checklists and assessment scales. Mental health surveys of this type have become so ubiquitous and influential that the psychometric methods that are at the heart of them seem to be beyond reproach. Are these the right tools to do the job of capturing the minds of general populations? This ...

Chronic pelvic pain (CPP) is highly prevalent among women and the condition is poorly understood. In addition to multiple symptoms from the pelvis, CPP patients frequently suffer bodily distress like musculoskeletal pain and negative emotional, behavioral, and sexual implications. This paper is based on a qualitative study including semi-structured interviews with eight women with CPP. Our project ...

This thesis focuses on liver sinusoidal endothelial cells (LSEC) and one of their characteristic features called fenestrations. LSEC line the hepatic sinusoids and filter solutes from the plasma. The bidirectional transport of solutes between the bloodstream and the interior of the liver is facilitated via transcellular nanopores called fenestrations. Fenestrations are dynamic structures with diameters ...

Objective - To explore whether plaque and gingival bleeding are more frequently experienced by adolescents with juvenile idiopathic arthritis (JIA) compared to matched controls without JIA; explore whether surface- and site-specific periodontal outcomes vary between the two groups; and for participants with JIA, investigate associations between disease-specific features and periodontal outcomes.<p ...

Internalizing problems may be associated with poor academic performance and school absenteeism among youth. This study investigated the impact of the EMOTION: “Coping Kids” Managing Anxiety and Depression Program on academic achievement and school adaptation in children. Data were collected in a national cluster-randomized controlled trial at three time points in Norway. Children (N = 688, 8–12 ...

Background - When a child welfare service agency receives a report of concern, there is an initial screening to decide whether an investigation needs to be initiated. In addition to the decision maker, case factors, external factors, and organizational factors have an impact on decision making in Child Welfare Services (CWS). Few recent studies have considered the impact of case factors on the initial ...

Background - In ulcerative colitis (UC), the molecular mechanisms that drive disease development and patient response to therapy are not well understood. A significant proportion of patients with UC fail to respond adequately to biologic therapy. Therefore, there is an unmet need for biomarkers that can predict patients’ responsiveness to the available UC therapies as well as ascertain the most ...

Purpose - Data quality is essential for all types of research, including health registers. However, data quality is rarely reported. We aimed to assess the accuracy of data in a national spine register (NORspine) and its agreement with corresponding data in electronic patient records (EPR).<p> <p>Methods - We compared data in NORspine registry against data in (EPR) for 474 patients operated for ...

Objectives - To analyze rates, odds ratios (OR), and characteristics of screen-detected and interval cancers after concordant and discordant initial interpretations and consensus in a population-based screening program.<p> <p>Methods - Data were extracted from the Cancer Registry of Norway for 487,118 women who participated in BreastScreen Norway, 2006–2017, with 2 years of follow-up. All mammograms ...

Background - Manual assessment of bone marrow signal is time-consuming and requires meticulous standardisation to secure adequate precision of findings.<p> <p>Objective - We examined the feasibility of using deep learning for automated segmentation of bone marrow signal in children and adolescents.<p> <p>Materials and methods - We selected knee images from 95 whole-body MRI examinations of ...