Det helsevitenskapelige fakultet: Recent submissions

Now showing items 401-420 of 10396

    • Seksuelle overgrep begått av voksne eller jevnaldrende: risikofaktorer, psykisk helse og livskvalitet i et representativt ungdomsutvalg 

      Schaathun, Iris Linnea; Nenseth, Ian Revhaug (Mastergradsoppgave; Master thesis, 2022-02-15)
      Bakgrunn: Rundt halvparten av seksuelle overgrep mot barn og unge begås av jevnaldrende, likevel vet vi lite om forskjeller i risikofaktorer og helsekonsekvenser relatert til om overgriperen har vært voksen eller jevnaldrende. Formål: Studien undersøker risikofaktorer, psykisk helse og livskvalitet relatert til seksuelle overgrep, og forskjeller relatert til om overgrepet ble begått av voksne eller ...

    • “I See What You Feel”: An Exploratory Study to Investigate the Understanding of Robot Emotions in Deaf Children 

      Cirasa, Carla; Høgsdal, Helene; Conti, Daniela (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-02-09)
      Research in the field of human–robot interactions (HRIs) has advanced significantly in recent years. Social humanoid robots have undergone severe testing and have been implemented in a variety of settings, for example, in educational institutions, healthcare facilities, and senior care centers. Humanoid robots have also been assessed across different population groups. However, research on various ...

    • Homologous Recombination Deficiency Across Subtypes of Primary Breast Cancer 

      Yndestad, Synnøve; Engebrethsen, Christina; Herencia-Ropero, A.; Nikolaienko, Oleksii; Vintermyr, Olav Karsten; Lillestøl, Reidun Kristine; Minsaas, Laura; Leirvaag, Beryl; Iversen, Gjertrud Titlestad; Gilje, Bjørnar; Blix, Egil Støre; Espelid, Helge; Lundgren, Steinar; Geisler, Jürgen; Aase, Hildegunn Siv; Aas, Turid; Gudlaugsson, Einar; Llop-Guevara, Alba; Serra, Violeta; Janssen, Emiel; Lønning, Per Eystein; Knappskog, Stian; Eikesdal, Hans Petter (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-01)
      Purpose - Homologous recombination deficiency (HRD) is highly prevalent in triple-negative breast cancer (TNBC) and associated with response to PARP inhibition (PARPi). Here, we studied the prevalence of HRD in non-TNBC to assess the potential for PARPi in a wider group of patients with breast cancer.<p> <p>Methods - HRD status was established using targeted gene panel sequencing (360 genes) and ...

    • Evaluation of Sexual Behavior in Laboratory vs Seminatural Conditions 

      Chu, Xi; Ågmo, Anders j (Chapter; Bokkapittel, 2023-05-17)
      Sexual behavior is, by necessity, sexually dimorphic. Males transfer sperm to females, whereas females receive sperm from males. Discussions of sex differences in copulatory behavior are consequently trivial. However, the behaviors associated with copulation, for example mate choice or postcopulatory reactions, may well be similar in males and females. Such differences, even subtle, are far easier ...

    • Personsentrert sykepleiefaglig ledelse og arbeidskultur 

      Drageset, Ingrid Marie Saga; Nicolaisen, Ragnhild Kristin; Johannessen, Karin (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-09-29)
      The aim of this qualitative research project is to explore how person-centred nursing leadership can promote work culture in nursing homes. The focus is on leaders and caregivers at a department level in the nursing home. Interviews were analysed by content analysis and theoretical perspectives from person-centred nursing leadership. Professional cooperation, present and perceptive leaders, as well ...

    • Climate Change Causes Molecular-Level Stress Responses 

      Urbarova, Ilona (Journal article; Tidsskriftartikkel, 2019)
      Anemones are abundant in an acidified ocean. But are they thriving? New genomics research shows that ocean acidification puts these animals under considerable stress. The good news is that some marine animals can tolerate the impacts of increased carbon dioxide levels in seawater.

    • Er legerollen uforenlig med dødshjelp? 

      Blomkvist, Andreas Wahl; Zadig, Pia Karin Karlsen; Ryssdal, Martin; Zahid, Wasim; Schei, Edvin; Nylander, Gro; Stojanovic, Filip; Solberg, Carl Tollef (Journal article; Tidsskriftartikkel; Peer reviewed, 2023)
      En problemstilling idødshjelpsdeba en er hvordan dødshjelp kan forenes etisk med rollen som helsepersonell, og spesielt med rollen som behandlende lege. Andelen leger som stø er legalisering av dødshjelp er økende, og en prosess for åavklare legens mulige oppgaver ved livets slu er derfor betimelig. Legeyrket innebærer ere faglige roller, en av dem er åvære sakkyndig. Vi skisserer en hypotetisk ...

    • Lifestyle interventions to change trajectories of obesity-related cardiovascular risk from childhood onset to manifestation in adulthood: a joint scientific statement of the task force for childhood health of the European Association of Preventive Cardiology and the European Childhood Obesity Group 

      Hanssen, Henner; Moholdt, Trine; Bahls, Martin; Biffi, Alessandro; Siegrist, Monika; Lewandowski, Adam J.; Biondi-Zoccai, Giuseppe; Cavarretta, Elena; Kokkvoll, Ane Sofie; Løchen, Maja-Lisa; Maestrini, Viviana; Pinto, Rita Salvador; Palermi, Stefano; Thivel, David; Wojcik, Malgorzata; Hansen, Dominique; Van Craenenbroeck, Emeline M.; Weghuber, Daniel; Kraenkel, Nicolle; Tiberi, Monica (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-25)
      There is an immediate need to optimize cardiovascular (CV) risk management and primary prevention of childhood obesity to timely and more effectively combat the health hazard and socioeconomic burden of CV disease from childhood development to adulthood manifestation. Optimizing screening programs and risk management strategies for obesity-related CV risk in childhood has high potential to change ...

    • National health registries – a ‘goldmine’ for studying non-communicable disease occurrence in Norway – the NCDNOR project 

      Nystad, Wenche; Hjellvik, Vidar; Larsen, Inger Kristin; Robsahm, Trude Eid; Sund, Erik Reidar; Krokstad, Steinar; Hopstock, Laila Arnesdatter; Grimsgaard, Anne Sameline; Langhammer, Arnulf; Bramness, Jørgen Gustav; Wisløff, Torbjørn; Lergenmuller, Simon; Dalene, Knut Eirik; Meyer, Haakon Eduard; Holvik, Kristin; Helgeland, Jon; Karlstad, Øystein; Ariansen, Inger (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-10)
      To estimate occurrence of non-communicable diseases (NCDs) over the life-course in the Norwegian population, national health registries are a vital source of information since they fully represent the entire non-institutionalised population. However, as they are mainly established for administrative purposes, more knowledge about how NCDs are recorded in the registries is needed. To establish this, ...

    • Including measures of chronic kidney disease to improve cardiovascular risk prediction by SCORE2 and SCORE2-OP 

      Matsushita, Kunihiro; Kaptoge, Stephen; Hageman, Steven H J; Sang, Yingying; Ballew, Shoshana H.; Grams, Morgan E.; Surapaneni, Aditya; Sun, Luanluan; Arnlov, Johan; Bozic, Milica; Brenner, Hermann; Brunskill, Nigel J.; Chang, Alex R.; Chinnadurai, Rajkumar; Cirillo, Massimo; Correa, Adolfo; Ebert, Natalie; Eckardt, Kai-Uwe; Gansevoort, Ron T.; Gutierrez, Orlando; Hadaegh, Farzad; He, Jiang; Hwang, Shih-Jen; Jafar, Tazeen H.; Jassal, Simerjot K.; Kayama, Takamasa; Kovesdy, Csaba P.; Landman, Gijs W.; Levey, Andrew S.; Lloyd-Jones, Donald M.; Major, Rupert W.; Miura, Katsuyuki; Muntner, Paul; Nadkarni, Girish N.; Nowak, Christoph; Ohkubo, Takayoshi; Pena, Michelle J.; Polkinghorne, Kevan R.; Sairenchi, Toshimi; Schaeffner, Elke; Schneider, Markus P.; Shalev, Varda; Shlipak, Michael G.; Solbu, Marit Dahl; Stempniewicz, Nikita; Tollitt, James; Valdivielso, José M; van der Leeuw, Joep; Wang, Angela Yee-Moon; Wen, Chi-Pang; Woodward, Mark; Yamagishi, Kazumasa; Yatsuya, Hiroshi; Zhang, Luxia; Dorresteijn, Jannick A N; Di Angelantonio, Emanuele; Visseren, Frank L J; Pennells, Lisa; Coresh, Josef (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-16)
      Aims - The 2021 European Society of Cardiology (ESC) guideline on cardiovascular disease (CVD) prevention categorizes moderate and severe chronic kidney disease (CKD) as high and very-high CVD risk status regardless of other factors like age and does not include estimated glomerular filtration rate (eGFR) and albuminuria in its algorithms, systemic coronary risk estimation 2 (SCORE2) and systemic ...

    • Recommendations for the development, implementation, and reporting of control interventions in efficacy and mechanistic trials of physical, psychological, and self-management therapies: the CoPPS Statement 

      Hohenschurz-Schmidt, David; Vase, Lene; Scott, Whitney; Annoni, Marco; Ajayi, Oluwafemi K; Barth, Jürgen; Bennell, Kim; Berna, Chantal; Bialosky, Joel; Braithwaite, Felicity; Finnerup, Nanna B.; de C Williams, Amanda C; carlino, elisa; Ceritelli, Francesco; Chaibi, Aleksander; Cherkin, Dan; Colloca, Luana; Cote, Pierre; Darnall, Beth D; Evans, Roni; Fabre, Laurent; Faria, Vanda; French, Simon D; Gerger, Heike; Häuser, Winfried; Hinman, Rana S.; Ho, Dien; Janssens, Thomas; Jensen, Karin; Johnston, Chris; Juhl Lunde, Sigrid; Keefe, Francis; Kerns, Robert D; Koechlin, Helen; Kongsted, Alice; Michener, Lori A; Moerman, Daniel E; Musial, Frauke; Newell, David; Nicholas, Michael; Palermo, Tonya M; Palermo, Sara; Peerdeman, Kaya J.; Pogatzky-Zahn, Esther M; Puhl, Aaron A; Roberts, Lisa; Rossettini, Giacomo; Tomczak Matthiesen, Susan; Underwood, Martin; Vaucher, Paul; Vollert, Jan; Wartolowska, Karolina; Weimer, Katja; Werner, Christoph Patrick; Rice, Andrew S C; Draper-Rodi, Jerry (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-25)
      Control interventions (often called “sham,” “placebo,” or “attention controls”) are essential for studying the efficacy or mechanism of physical, psychological, and self-management interventions in clinical trials. This article presents core recommendations for designing, conducting, and reporting control interventions to establish a quality standard in non-pharmacological intervention research. A ...

    • Variation in antibiotic consumption in very preterm infants-a 10 year population-based study 

      Huncikova, Zuzana; Stensvold, Hans Jørgen; Øymar, Knut Asbjørn Alexander; Vatne, Anlaug; Lang, Astri Maria; Støen, Ragnhild; Brigtsen, Anne Karin; Moster, Dag; Eriksen, Beate Horsberg; Selberg, Terje Reidar; Rønnestad, Arild Erland; Klingenberg, Claus (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-21)
      Objectives: Wide variations in antibiotic use in very preterm infants have been reported across centres despite similar rates of infection. We describe 10 year trends in use of antibiotics and regional variations among very preterm infants in Norway. Patients and Methods: All live-born very preterm infants (<32 weeks gestation) admitted to any neonatal unit in Norway during 2009–18 were included. ...

    • What is a High-Quality Moral Case Deliberation?-Facilitators’ Perspectives in the Euro-MCD Project 

      Jakobsen, Lena M; Molewijk, Bert; de Snoo-Trimp, Janine; Svantesson, Mia; Ursin, Gøril (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-02-05)
      The evaluation of the European Moral Case Deliberation Outcomes project (EuroMCD) has resulted in a revised evaluation instrument, knowledge about the content of MCD (moral case deliberation), and the perspectives of those involved. In this paper, we report on a perspective that has been overlooked, the facilitators’. We aim to describe facilitators’ perceptions of high-quality moral case ...

    • Outcome of aneurysmal subarachnoid hemorrhage in a population-based cohort: Retrospective registry study 

      Iversen, Mathilde Vea (Master thesis; Mastergradsoppgave, 2023-10-31)
      Background: Studies of aneurysmal subarachnoid hemorrhage (aSAH) report an association between higher patient volumes and better outcomes. In regions with dispersed settlement, this must be balanced against the advantages with shorter pre-hospital transport times and timely access. The aim of this study is to report outcome for unselected aSAH-cases from a well-defined rural population treated in a ...

    • Treatment of Cardiovascular Dysfunction With PDE5-Inhibitors – Temperature Dependent Effects on Transport and Metabolism of cAMP and cGMP 

      Selli, Anders Lund (Master thesis; Mastergradsoppgave, 2023-10-21)
      Introduction: Cardiovascular dysfunction is a potentially lethal complication of hypothermia. Due to a knowledge gap, pharmacological interventions are not recommended at core temperatures below 30°C. Yet, further cooling is induced in surgical procedures and survival of accidental hypothermia is reported after rewarming from below 15°C, advocating a need for evidence-based treatment guidelines. In ...

    • Performance and clinical applicability of machine learning in liver computed tomography imaging: a systematic review 

      Joakimsen, Henrik Lykke (Master thesis; Mastergradsoppgave, 2023-09-12)
      Abstract Objectives: Machine learning (ML) for medical imaging is emerging for several organs and image modalities. Our objectives were to provide clinicians with an overview of this field by answering the following questions: (1) How is ML applied in liver computed tomography (CT) imaging? (2) How well do ML systems perform in liver CT imaging? (3) What are the clinical applications of ML in liver ...

    • Automated calibration for stability selection in penalised regression and graphical models 

      Bodinier, Barbara; Filippi, Sarah; Nøst, Therese Haugdahl; Chiquet, Julien; Chadeau-Hyam, Marc (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-13)
      Stability selection represents an attractive approach to identify sparse sets of features jointly associated with an outcome in high-dimensional contexts. We introduce an automated calibration procedure via maximisation of an in-house stability score and accommodating a priori-known block structure (e.g. multi-OMIC) data. It applies to [Least Absolute Shrinkage Selection Operator (LASSO)] penalised ...

    • Politiavhør av mistenkte barn under 15 år 

      Holm, Inger Marie; Jacobsen, Ioanna Dallari (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-13)
      Mistenkte barn avhøres etter de samme reglene som voksne, og det foreligger ingen krav til særlig kompetanse hos avhører. Det er per i dag ikke utviklet et tilpasset system for mistenkte barn under kriminell lavalder i politiavhør. Disse faktorer kan lede til en risiko for at barnas rettssikkerhet potensielt settes i fare. Med utgangspunkt i gjeldende rett drøftes hvorvidt det gjelder særregler ved ...

    • Pragmatic randomized controlled trial comparing a complex telemedicine-based intervention with usual care in patients with chronic conditions 

      Sten-Gahmberg, Susanna; Sten-gahmberg, Susanna; Pedersen, Kine; Harsheim, Ingrid gaarder; Løyland, Hanna Isabel; Snilsberg, Øyvind; Iversen, Tor; Godager, Geir; Sæther, Erik Magnus; Abelsen, Birgit (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-01-31)
      This study evaluates a complex telemedicine-based intervention targeting patients with chronic health problems. Computer tablets and home telemonitoring devices are used by patients to report point-of-care measurements, e.g., blood pressure, blood glucose or oxygen saturation, and to answer health-related questions at a follow-up center. We designed a pragmatic randomized controlled trial to compare ...

    • Evaluering av pilotprosjekt med primærhelseteam og alternative finansieringsordninger. Statusrapport 2 

      Abelsen, Birgit; Gaski, Margrete; Godager, Geir; Iversen, Tor; Løyland, Hanna Isabel; Pedersen, Kine; Snilsberg, Øyvind (Research report; Forskningsrapport, 2019-12-02)
      I evalueringens andre statusrapport har vi undersøkt hvordan arbeidet med primærhelseteam (PHT) foregår og fungerer ved alle legekontorene som inngår i forsøket. Arbeidet med PHT er godt i gang ved alle legekontorene, selv om oppstarten for mange har tatt tid. Antallet pasienter som omfattes av PHT er økende. Det er stor variasjon i organisering av teamarbeidet på legekontorene. Sykepleiernes innsats ...