Det helsevitenskapelige fakultet: Recent submissions

Now showing items 4281-4300 of 10619

    • Uveitis in Juvenile Idiopathic Arthritis 18-Year Outcome in the Population-based Nordic Cohort Study 

      Rypdal, Veronika Gjertsen; Glerup, Mia; Songstad, Nils Tomas; Bertelsen, Geir; Christoffersen, Terje; Arnstad, Ellen D.; Aalto, Kristiina; Berntson, Lillemor; Fasth, Anders; Herlin, Troels; Ekelund, Maria; Peltoniemi, Suvi; Toftedal, Peter; Nielsen, Susan; Leinonen, Sanna; Bangsgaard, Regitze; Nielsen, Rasmus; Rygg, Marite; Nordal, Ellen (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08-28)
      <i>Purpose</i> - To assess the long-term outcome of uveitis in juvenile idiopathic arthritis (JIA).<p> <p><i>Design</i> - Population-based, multicenter, prospective JIA cohort, with a cross-sectional assessment of JIA-associated uveitis (JIA-U) 18 years after the onset of JIA.<p> <p><i>Participants</i> - A total of 434 patients with JIA, of whom 96 had uveitis, from defined geographic areas of ...

    • Revisiting the radiographic assessment of osteoporosis-Osteopenia in children 0-2 years of age. A systematic review 

      Rosendahl, Karen; Lundestad, Anette; Bjørlykke, John Asle; Lein, Regina Küfner; Angenete, Oskar W; Augdal, Thomas Angell; Müller, Lil-Sofie Ording; Jaramillo, Diego (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-11-02)
      <i>Background</i> - Imaging for osteoporosis has two major aims, first, to identify the presence of low bone mass (osteopenia), and second, to quantify bone mass using semiquantitative (conventional radiography) or quantitative (densitometry) methods. In young children, densitometry is hampered by the lack of reference values, and high-quality radiographs still play a role although the evaluation ...

    • Prevalence of temporomandibular disorder in children and adolescents with juvenile idiopathic arthritis – a Norwegian cross- sectional multicentre study 

      Fischer, Johannes Maria; Skeie, Marit Slåttelid; Rosendahl, Karen; Tylleskär, Karin; Lie, Stein Atle; Shi, Xie-Qi; Gil, Elisabeth Grut; Cetrelli, Lena Elisabet; Halbig, Josefine Mareile; Marti, Larissa von Wangenheim; Rygg, Marite; Frid, Paula; Stoustrup, Peter; Rosén, Annika (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-13)
      <i>Background</i> - Children and adolescents with juvenile idiopathic arthritis (JIA) may suffer pain from temporomandibular disorder (TMD). Still, routines for the assessment of temporomandibular joint (TMJ) pain in health and dental care are lacking. The aims of this study were to examine the prevalence of TMD in children and adolescents with JIA compared to their healthy peers and to investigate ...

    • Weather Conditions and Outdoor Fall Injuries in Northwestern Russia 

      Unguryanu, Tatiana Nikolaevna; Grjibovski, Andrej; Trovik, Tordis A; Ytterstad, Børge; Kudryavtsev, Alexander V (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08-21)
      This study aimed to investigate associations between the weather conditions and the frequency of medically-treated, non-fatal accidental outdoor fall injuries (AOFIs) in a provincial region of Northwestern Russia. Data on all non-fatal AOFIs that occurred from January 2015 through June 2018 (<i>N</i> = 1125) were extracted from the population-based Shenkursk Injury Registry (SHIR). Associations ...

    • Betydninger af naturmøder - Et studie af vandrendes oplevelser, erfaring og mening fra stien Sørøya på langs 

      Nielsen, Rikki Egon (Master thesis; Mastergradsoppgave, 2020-05-20)
      Betydninger af naturmøder - Et studie af vandrendes oplevelser, erfaring og mening fra stien Sørøya på langs. Studien fokuserer på hvilken betydning oplevelserne fra stien Sørøya på langs har for de vandrende. Hensigten med studiet er at forstå de vandrendes oplevelser i lyset af et socialt og kundskabsbaseret perspektiv. Studiets forskningsspørgsmål er: Hvilken betydning har oplevelserne ...

    • Brukermedvirkning i hjemmetjenesten En studie om brukermedvirkning sett fra et brukerperspektiv 

      Strønen, Kathrine P. (Master thesis; Mastergradsoppgave, 2020-11-03)
      Hensikt og bakgrunn: Hensikten med oppgaven er å utforske begrepet brukermedvirkning. Og da hvordan brukere av kommunale hjemmetjenester forstår og bruker dette begrepet i sin hverdag. Brukermedvirkning er en lovfestet rettighet, men det er uklart hvorvidt brukere av kommunale hjemmetjenester er klar over dette. Bakgrunn for studien er basert på både personlige erfaringer som pårørende og på faglige ...

    • Salivary Oral Microbiome of Children With Juvenile Idiopathic Arthritis: A Norwegian Cross-Sectional Study 

      Frid, Paula; Baraniya, Divyashri; Halbig, Josefine Mareile; Rypdal, Veronika Gjertsen; Songstad, Nils Thomas; Rosén, Annika; Berstad, Johanna Elisabeth Rykke; Flatø, Berit; Alakwaa, Fadhl; Gil, Elisabeth Grut; Cetrelli, Lena Elisabet; Chen, Tsute; Al-hebshi, Nezar Noor; Nordal, Ellen Berit; Al-Haroni, Mohammed (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-11-04)
      <i>Background</i>: The oral microbiota has been connected to the pathogenesis of rheumatoid arthritis through activation of mucosal immunity. The objective of this study was to characterize the salivary oral microbiome associated with juvenile idiopathic arthritis (JIA), and correlate it with the disease activity including gingival inflammation.<p> <i>Methods</i>: Fifty-nine patients with JIA ...

    • Scoping maternal care through the lens of maternal deaths: A retrospective analysis of maternal mortality in Georgia 

      Skhvitaridze, Natia; Anda, Erik Eik; Brenn, Tormod; Kintraia, Nikoloz; Gamkrelidze, Amiran (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-01)
      <i>Introduction</i> - Reduction of the maternal mortality ratio (MMR) to 12 per 100,000 live births by 2030 is a priority target in Georgia. This study aims to assess and classify MM in Georgia by direct and indirect causes of death from 2014 to 2017, using data from the national surveillance system and in accordance with internationally approved criteria.<p> <p><i>Material and methods</i> - In ...

    • Opplærings‐ og informasjonstiltak for barn og unge for å forebygge og avdekke vold, overgrep og krenkelser: en systematisk kartleggingsoversikt 

      Blaasvær, Nora; Baiju, Nikita (Research report; Forskningsrapport, 2019)
      Mange barn som vokser opp med vold, overgrep og krenkelser i hjemmet kjenner ingen annen virkelighet. De vet ofte ikke at det de erfarer ikke er greit, og har dermed ikke kunnskapen de behøver for å be om hjelp. For eldre barn og ungdommer kan det være vanskelig å vite hvor grensene for hva som er overgrep går. Forskning viser at barn og ungdom som blir utsatt for vold og seksuelle overgrep har ...

    • Barnevernets undersøkelsesarbeid Når barnevernet undersøker, delrapport 4 

      Christiansen, Øivin; Havnen, Karen J Skaale; Iversen, Anette Christine; Fylkesnes, Marte Knag; Lauritzen, Camilla; Nygård, Reidunn Håøy; Vis, Svein Arild; Jarlby, Fredrikke (Research report; Forskningsrapport, 2019-10)
      Dette er den fjerde delrapporten fra prosjektet «Barnevernets undersøkelsesarbeid – fra bekymring til beslutning». Rapporten baserer seg på analyse av 1123 barnevernssaker samt intervju med ledere og saksbehandlere. Forskningen som formidles i denne rapporten følger undersøkelsesprosessen fra barnevernstjenesten har besluttet at meldingen skal undersøkes til undersøkelsen er gjennomført og det ...

    • Utvikling av indikatorer på NCD området knyttet til rapportering for den globale og nasjonale NCD strategien 

      Ariansen, Inger; Nystad, Wenche; Graff-Iversen, Sidsel; Gulseth, Hanne Løvdal; Meyer, Haakon E; Brunborg, Geir Scott; Vedøy, Tord Finne; Vollset, Stein Emil; Reneflot, Anne; Nerhus, Kjersti Andersen; Henrichsen, Svein Høegh; Huseby, Beate Margrethe; Nylenna, Astrid; Anderssen, Sigmund Alfred; Ekelund, Ulf; Krokstad, Steinar; Møller, Bjørn; Weiderpass, Elisabete; Tell, Grethe S.; Gram, Inger Torhild; Grimsgaard, Sameline; Njølstad, Inger; Bakke, Per; Husebø, Gunnar (Research report; Forskningsrapport, 2017-04)
      Norge har sluttet seg til WHO sitt mål om 25% reduksjon 2010 til 2025 i for tidlig død som følge av de fire ikke-smittsomme sykdommene (noncommunicale disease, NCD); kreft, hjerte- og karsykdom, diabetes og kronisk lungesykdom. Bakgrunnen er at disse fire sykdomsgruppene langt på vei kan forebygges ved å redusere de fire felles risikofaktorene røyking, usunn kost, stillesitting og skadelig bruk ...

    • Whole-body magnetic resonance imaging in children – how and why? A systematic review 

      Zadig, Pia Karin Karlsen; von Brandis, Elisabeth; Lein, Regina Küfner; Rosendahl, Karen; Avenarius, Derk; Müller, Lil-Sofie Ording (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-25)
      Whole-body magnetic resonance imaging (MRI) is increasingly being used for a number of indications. Our aim was to review and describe indications and scan protocols for diagnostic value of whole-body MRI for multifocal disease in children and adolescents, we conducted a systematic search in Medline, Embase and Cochrane for all published papers until November 2018. Relevant subject headings and free ...

    • Qualitative Evaluations of mHealth Interventions: Current Gaps and Future Directions 

      Bradway, Meghan; Leibowitz, Kari; Garrison, Kathleen A.; Howe, Lauren; Årsand, Eirik (Journal article; Tidsskriftartikkel; Peer reviewed, 2020)
      Psycho-social factors are often addressed in behavioral health studies. While the purpose of many mHealth interventions is to facilitate behavior change, the focus is more prominently on the functionality and usability of the technology and less on the psycho-social factors that contribute to behavior change. Here we aim to identify the extent to which mHealth interventions for patient self- management ...

    • Persistent pain associated with socioeconomic and personal factors in a Sami and Non-Sami population in Norway: an analysis of SAMINOR 2 survey data 

      Damsgård, Elin; Thrane, Gyrd; Fleten, Nils; Bagge, Johan; Sørlie, Tore; Anke, Audny; Broderstad, Ann Ragnhild (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08-11)
      In international studies, higher prevalence of persistent pain has been reported in indigenous populations compared to majority populations. The present study aimed to determine the prevalence of persistent pain within a Sami and a non-Sami population in northern Norway, with adjustment for the confounding factors of age, sex, marital status, education, income, mental health, smoking status and ...

    • Levels of mental distress over 18 years after entering treatment for substance use disorders: A longitudinal cohort study 

      Hjemsæter, Arne Jan; Bramness, Jørgen Gustav; Drake, Robert; Skeie, Ivar; Monsbakken, Bent Berntsen; Saltyte Benth, Jurate; Landheim, Anne (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08-17)
      <i>Aims:</i> The aims were to investigate whether baseline characteristics and problematic substance use were related to change in mental distress over time in patients with substance use disorders during an 18-year period.<p> <p><i>Method:</i> This was a prospective, longitudinal study of patients followed for 18 years after entering specialised treatment for substance use disorders. A sample ...

    • Centralizing a national pancreatoduodenectomy service: striking the right balance 

      Nymo, Linn Såve; Kleive, Dyre; Waardal, Kim; Bringeland, Erling Audun; Søreide, Jon Arne; Labori, Knut Jørgen; Mortensen, Kim Erlend; Søreide, Kjetil; Lassen, Kristoffer (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-07)
      <i>Background</i> - Centralization of pancreatic surgery is currently called for owing to superior outcomes in higher‐volume centres. Conversely, organizational and patient concerns speak for a moderation in centralization. Consensus on the optimal balance has not yet been reached. This observational study presents a volume–outcome analysis of a complete national cohort in a health system with ...

    • User-centred Design with a Remote Approach: Experiences from the Chronic Pain Project 

      Smaradottir, Berglind; Bellika, Johan Gustav; Fredeng, Aina; Fagerlund, Asbjørn Johansen (Journal article; Tidsskriftartikkel; Peer reviewed, 2020)
      User-centred design involves end-users or user groups during all the parts of the development process. The research project Chronic Pain aims to develop a shared decision making application for patients and physicians, addressing individually adapted pain treatment. The project employs a user-centred design process, and in middle of it, Covid-19 pandemic social distancing restrictions were imposed. ...

    • Sykepleiernes utfordringer ved bruk av tvang i en liten kommune. En kvalitativ studie av sykepleiernes utfordringer i møte med pasienter og innleggelser ved bruk av tvang 

      Olsen, Vibeke Bjørkli (Master thesis; Mastergradsoppgave, 2020-11-02)
      Bakgrunn for studiet er å se på hvilke erfaringer sykepleierne har i møte med pasienter med alvorlig psykiske lidelser. I september 2017 ble det gjort endring i lov om psykisk helsevern hvor styrkning av pasientens samtykkekompetanse og rettsikkerhet skulle bidra til forebygging og minske bruke av tvang. hensikten med studiet er å belyse kompetansen og bevisstgjøring innen for eget arbeidsfelt i ...

    • ATAD3 proteins in autophagy. Do ATAD3 proteins have a direct role in regulating autophagy 

      Taboko, Nelsy Efundem (Master thesis; Mastergradsoppgave, 2020-05-22)
      ATPase Family AAA Domain -containing protein 3 (ATAD3) is a nuclear-encoded mitochondrial transmembrane protein encompassing three isoforms; ATAD3A, ATAD3B and ATAD3C. ATAD3 is involved in several cellular process and available data predict that ATAD3A and ATAD3B proteins may have potential roles in regulating autophagy and mitophagy. Preliminary data from our research group identified interactions ...

    • A study of TRIM32 self-ubiquitination 

      Khan, Waqas (Master thesis; Mastergradsoppgave, 2020-05-15)
      TRIMs (tripartite motif proteins) constitute a family of ubiquitin E3 ligases that are involved in a variety of cellular processes including autophagy and carcinogenesis. TRIM32 contains an N-terminal RING finger domain, B-box region, a coiled-coil domain and six NHL repeats in the C-terminal region, which are involved in protein dimerization and substrate recognitions. Various mutations in the NHL ...