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norskDet helsevitenskapelige fakultet: Nye registreringer
Viser treff 2901-2920 av 10433
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Electrospinning of chloramphenicol-containing nanofibrous dressings for treatment of chronic wounds
(Conference object; Konferansebidrag, 2021-03-10)<p><i>Background</i> An efficient treatment is crucial to overcome the delayed healing process and high infection rate in chronic wounds. Nanofibrous dressings, having a nano‐sized fiber structure, can enhance cell ingrowth and support the healing process. In addition, nanofibers can deliver active ingredients e.g. antibiotics into the wound to treat wound infection. By incorporating broad‐spectrum ... -
Equitable access to cancer patient pathways in Norway – a national registry-based study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-25)Background: In 2015, cancer patient pathways (CPP) were implemented in Norway to reduce unnecessary non-medical delay in the diagnostic process and start of treatment. The main aim of this study was to investigate the equality in access to CPPs for patients with either lung, colorectal, breast or prostate cancer in Norway.<p> <p>Methods: National population-based data on individual level from ... -
One-Year Remission Rate of Chronic Headache Comparing Video and Face-to-Face Consultations by Neurologist: Randomized Controlled Trial
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-13)Background: Chronic headache causing severe headache-related disability for those affected by the disease is under- or misdiagnosed in many cases and therefore requires easy access to a specialist for optimal health care management.<p> <p>Objective: The goal of the research is to determine whether video consultations are noninferior to face-to-face consultations in treating chronic headache ... -
Jeg liker å bestemme, når jeg får bestemme - En kvalitativ studie av hvordan arbeidstakere med utviklingshemming opplever selvbestemmelse i prosessen mot arbeid på en ordinær arbeidsplass, og på den ordinære arbeidsplassen.
(Master thesis; Mastergradsoppgave, 2021-05-13)Masteroppgaven er basert på kvalitative semi-strukturerte intervjuer med fem arbeidstakere med utviklingshemming, som jobber hele eller deler av arbeidstiden på en ordinær arbeidsplass. Problemstillingen som undersøkes er hvordan arbeidstakere med utviklingshemming opplever sin selvbestemmelse i prosessen mot arbeid på en ordinær arbeidsplass, og på den ordinære arbeidsplassen. I tillegg undersøkes ... -
Serum miR371 in testicular germ cell cancer before and after orchiectomy, assessed by digital-droplet PCR in a prospective study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-02)MicroRNA-371a-3p (miR371) has been suggested as a sensitive biomarker in testicular germ cell cancer (TGCC). We aimed to compare miR371 with the classical biomarkers α-fetoprotein (AFP) and β-human chorionic gonadotropin (hCG<sub>β</sub>). Overall, 180 patients were prospectively enrolled in the study, with serum samples collected before and after orchiectomy. We compared the use of digital droplet ... -
M-ficolin: a valuable biomarker to identify leukaemia from juvenile idiopathic arthritis
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-22)Objective: Distinction on clinical grounds between acute lymphoblastic leukaemia presenting with arthropathy (ALLarthropathy) and juvenile idiopathic arthritis (JIA) is difficult, as the clinical and paraclinical signs of leukaemia may be vague. The primary aim was to examine the use of lectin complement pathway proteins as markers to differentiate ALLarthropathy from JIA. The secondary aims were ... -
An introduction to network analysis for studies of medication use
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-29)Background - Network Analysis (NA) is a method that has been used in various disciplines such as Social sciences and Ecology for decades. So far, NA has not been used extensively in studies of medication use. Only a handful of papers have used NA in Drug Prescription Networks (DPN). We provide an introduction to NA terminology alongside a guide to creating and extracting results from the medication ... -
Intervention fidelity and process outcomes of the IMMENSE study, a pharmacist-led interdisciplinary intervention to improve medication safety in older hospitalized patients
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-21)What is known and Objective - The majority of hospitalized older patients experience medication-related problems (MRPs), and there is a call for interventions to solve MRPs and improve clinical outcomes like medical visits. The IMMENSE study is a randomized controlled trial investigating the impact of a pharmacist-led interdisciplinary intervention on emergency medical visits. Its multistep intervention ... -
Heart Angiotensin- Converting Enzyme and Angiotensin-Converting Enzyme 2 Gene Expression Associated With Male Sex and Salt-Sensitive Hypertension in the Dahl Rat.
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-19)Angiotensin-converting enzyme 2 (ACE 2) in the heart including its sex dependency in the hypertensive heart, has not been much studied compared to ACE. In the present study, we used the Dahl salt-sensitive rat exposed to fructose and salt to model a hypertensive phenotype in males, females, and ovariectomized females. Blood pressure was measured by the tale-cuff technique in the conscious state. ... -
Occupational Allergic Sensitization Among Workers Processing King Crab (Paralithodes camtschaticus) and Edible Crab (Cancer pagurus) in Norway and Identification of Novel Putative Allergenic Proteins
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-23)Introduction: Asthma and allergy occur frequently among seafood processing workers, with the highest prevalence seen in the crustacean processing industry. In this study we established for the first time the prevalence of allergic sensitization in the Norwegian king- and edible crab processing industry and characterized the IgE-reactive proteins.<p> <p>Materials and Methods: Two populations of ... -
A high-throughput multiplexing and selection strategy to complete bacterial genomes
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-09)Background: Bacterial whole-genome sequencing based on short-read technologies often results in a draft assembly formed by contiguous sequences. The introduction of long-read sequencing technologies permits those contiguous sequences to be unambiguously bridged into complete genomes. However, the elevated costs associated with long-read sequencing frequently limit the number of bacterial isolates ... -
MRI in the Assessment of TMJ-Arthritis in Children with JIA; Repeatability of a Newly Devised Scoring System
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-19)Rationale and Objectives: The temporomandibular joint (TMJ) is commonly involved in children with juvenile idiopathic arthritis. The diagnosis and evaluation of the disease progression is dependent on medical imaging. The precision of this imaging is under debate. SeveralR scoring systems have been proposed but transparent testing of the precision of the constituents of the scoring systems is ... -
Prevalence and antimicrobial resistance profiles of respiratory microbial flora in African children with HIV-associated chronic lung disease
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-25)<b>Background</b> HIV-associated chronic lung disease (CLD) is common among children living with HIV (CLWH) in sub-Saharan Africa, including those on antiretroviral therapy (ART). However, the pathogenesis of CLD and its possible association with microbial determinants remain poorly understood. We investigated the prevalence, and antibiotic susceptibility of <i>Streptococcus pneumoniae </i>(SP), ... -
Kunnskapsoppsummering og klassifisering av tiltaket: Respekt (2. utg.)
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-23)Respektprogrammet er et skoleomfattende utviklingsprogram for å forebygge og redusere problematferd hos elever. Programmet beskriver hvordan en skole gjennom en innovasjonsprosess blant skolens ansatte kan utvikle og implementere tiltak basert på programmets fire prinsipp; myndig klasseledelse, at tiltakene gjennomsyrer alle deler av skolens virksomhet (bredde), at de ulike tiltakene samsvarer ... -
The Norwegian Society for Pharmacoepidemiology
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-16)The Norwegian Society for Pharmacoepidemiology (NFFE) is a multidisciplinary, nation-wide network of professionals involved in the field of pharmacoepidemiology. Pharmacoepidemiology is the science that bridges epidemiologic methodology with clinical pharmacology and clinical pharmacy, for studying the use, effectiveness, value and safety of pharmaceuticals1 . The foundation of NFFE took into ... -
Association of iron deficiency with incident cardiovascular diseases and mortality in the general population
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-05)Aims - Although absolute (AID) and functional iron deficiency (FID) are known risk factors for patients with cardiovascular (CV) disease, their relevance for the general population is unknown. The aim was to assess the association between AID/FID with incident CV disease and mortality in the general population.<p> <p>Methods and results - In 12 164 individuals from three European population-based ... -
Incorporating kidney disease measures into cardiovascular risk prediction: Development and validation in 9 million adults from 72 datasets
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-04)Background: Chronic kidney disease (CKD) measures (estimated glomerular filtration rate [eGFR] and albuminuria) are frequently assessed in clinical practice and improve the prediction of incident cardiovascular disease (CVD), yet most major clinical guidelines do not have a standardized approach for incorporating these measures into CVD risk prediction. “CKD Patch” is a validated method to calibrate ... -
Fetal/neonatal alloimmune thrombocytopenia: A systematic review of impact of HLA-DRB3∗01:01 on fetal/neonatal outcome
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-27)The most common, severe cases of fetal and neonatal alloimmune thrombocytopenia among whites are caused by antibodies against human platelet antigen 1a (HPA-1a). The aims of this systematic review and meta-analysis are to determine the association between maternal HLA-DRB3*01:01 and: (1) HPA-1a-alloimmunization and (2) neonatal outcome in children born of HPA-1a-immunized women. A systematic ... -
Long-term quality of life among breast cancer survivors eligible for screening at diagnosis: a systematic review and meta-analysis
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-21)Objectives - This study aimed to explore the long-term quality of life (QoL) among breast cancer survivors eligible for mammographic screening at diagnosis and compare that to QoL among women with no history of breast cancer.<p> <p>Study design - Systematic review and meta-analysis.<p> <p>Methods - A systematic review of randomised controlled trials and observational studies published between ... -
Prediagnostic Blood Selenium Status and Mortality among Patients with Colorectal Cancer in Western European Populations
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-22)A higher selenium (Se) status has been shown to be associated with lower risk for colorectal cancer (CRC), but the importance of Se in survival after CRC diagnosis is not well studied. The associations of prediagnostic circulating Se status (as indicated by serum Se and selenoprotein P (SELENOP) measurements) with overall and CRC-specific mortality were estimated using multivariable Cox proportional ...
