Viser treff 1441-1460 av 10407

    • High prevalence of Merkel cell polyomavirus is associated with dysregulation in transcript levels of TLR9 and type I IFNs in a large cohort of CF patients from the Italian (Lazio) reference center for cystic fibrosis 

      Bitossi, Camilla; Viscido, Agnese; Prezioso, Carla; Brazzini, Gabriele; Trancassini, Maria; Borrazzo, Cristian; Passerini, Sara; Frasca, Federica; Scordio, Mirko; Sorrentino, Leonardo; Oliveto, Giuseppe; Fracella, Matteo; D'Auria, Alessandra; Selvaggi, Carla; Cimino, Giuseppe; Midulla, Fabio; Pierangeli, Alessandra; Antonelli, Guido; Moens, Ugo Lionel; Pietropaolo, Valeria; Scagnolari, Carolina (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-13)
      Merkel cell polyomavirus (MCPyV) has been detected in respiratory specimens including those from Cystic Fibrosis (CF) patients, raising questions about its immunological and clinical relevance in the respiratory tract. MCPyV might promote an inappropriate antiviral response contributing to a chronic inflammatory response and resulting in detrimental effects in CF. Respiratory samples (n = 1138) were ...
    • Overexpression of miR-20a-5p in Tumor Epithelium Is an Independent Negative Prognostic Indicator in Prostate Cancer — A Multi-Institutional Study 

      Stoen, Maria J.; Andersen, Sigve; Rakaee, Mehrdad; Pedersen, Mona I.; Ingebriktsen, Lise M.; Donnem, Tom; Lombardi, Ana P. G.; Kilvaer, Thomas K.; Busund, Lill-Tove R.; Richardsen, Elin (Master thesis; Mastergradsoppgave; Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-26)
      <p><i>Background:</i> MicroRNAs (miRs) have critical regulatory roles in cell functions, and are involved in prostate cancer tumorigenesis. miR-20a-5p is a member of the oncogenic miR-17-92 cluster. Overexpressed miR-20a-5p has been shown to increase both cell proliferation and cell migration in cancers. The aim of our cohort study was to evaluate the prognostic role of miR-20a-5p in prostate cancer. ...
    • Mobile app as a tool to collect health data: a survey on vaccination against COVID-19 

      Krieger, E.A.; Kudryavtsev, Alexander V; Samodova, O.V.; Bashkirev, D.S.; Mitkin, N.A.; Kontsevaya, A.V.; Postoev, V.A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022)
      Objective. To evaluate the feasibility of using a mobile app to collect health-related data and the impact of this data collection method on the results obtained, using the COVID-19 vaccination attitude assessment as an example. Material and methods. A survey was conducted on attitudes towards COVID-19 vaccination using the «Know Your Heart» mobile app. A total of 1,770 Arkhangelsk region residents ...
    • Regression-based norms for the FAS phonemic fluency test for ages 40–84 based on a Norwegian sample 

      Lorentzen, Ingrid Myrvoll; Espenes, Jacob; Hessen, Erik; Waterloo, Knut; Bråthen, Geir; Timón, Santiago; Aarsland, Dag; Fladby, Tormod; Bjørn-Eivind, Kirsebom (Mastergradsoppgave; Master thesis, 2023-01-06)
      The FAS phonemic fluency test is a commonly used neuropsychological test of executive function and processing speed. Although Norwegian discrete norms have been developed for the FAS test, American regression-based norms are frequently used by clinicians in Norway. However, language and cultural differences impact performance on the FAS test, and using foreign norms may not be appropriate. Moreover, ...
    • Cross-Ancestry Investigation of Venous Thromboembolism Genomic Predictors 

      Thibord, Florian; Klarin, Derek; Brody, Jennifer A.; Chen, Ming-Huei; Levin, Michael G.; Chasman, Daniel I.; Goode, Ellen L.; Hveem, Kristian; Teder-Laving, Maris; Martinez-Perez, Angel; Aïssi, Dylan; Daian-Bacq, Delphine; Ito, Kaoru; Natarajan, Pradeep; Lutsey, Pamela L.; Nadkarni, Girish N.; de Vries, Paul S.; Cuellar-Partida, Gabriel; Wolford, Brooke N.; Pattee, Jack W.; Kooperberg, Charles; Brækkan, Sigrid Kufaas; Li-Gao, Ruifang; Saut, Noemie; Sept, Corriene; Germain, Marine; Judy, Renae L.; Wiggins, Kerri L.; Ko, Darae; O'Donnell, Christopher J.; Taylor, Kent D.; Giulianini, Franco; De Andrade, Mariza; Nøst, Therese Haugdahl; Boland, Anne; Empana, Jean-Philippe; Koyama, Satoshi; Gilliland, Thomas; Do, Ron; Huffman, Jennifer E.; Wang, Xin; Zhou, Wei; Manuel Soria, Jose; Carlos Souto, Juan; Pankratz, Nathan; Haessler, Jeffery; Hindberg, Kristian Dalsbø; Rosendaal, Frits R; Turman, Constance; Olaso, Robert; Kember, Rachel L.; Bartz, Traci M.; Lynch, Julie A.; Heckbert, Susan R.; Armasu, Sebastian M.; Brumpton, Ben Michael; Smadja, David M.; Jouven, Xavier; Komuro, Issei; Clapham, Katharine R.; Loos, Ruth J F; Willer, Cristen J.; Sabater-Lleal, Maria; Pankow, James S.; Reiner, Alexander P.; Morelli, Vania Maris; Ridker, Paul M.; Vlieg, Astrid van Hylckama; Deleuze, Jean-François; Kraft, Peter; Rader, Daniel J.; Psaty, Bruce M.; Skogholt, Anne Heidi; Emmerich, Joseph; Suchon, Pierre; Rich, Stephen S.; Vy, Ha My T; Tang, Weihong; Jackson, Rebecca D.; Hansen, John Bjarne; Morange, Pierre-Emmanuel; Kabrhel, Christopher; Trégouët, David-Alexandre; Damrauer, Scott M.; Johnson, Andrew D.; Smith, Nicholas L. (Journal article; Tidsskriftartikkel, 2022)
      <p><i>Background:</i> Venous thromboembolism (VTE) is a life-threatening vascular event with environmental and genetic determinants. Recent VTE genome-wide association studies (GWAS) meta-analyses involved nearly 30 000 VTE cases and identified up to 40 genetic loci associated with VTE risk, including loci not previously suspected to play a role in hemostasis. The aim of our research was to expand ...
    • Factors associated with treatment satisfaction in patients with hidradenitis suppurativa: results from the Global VOICE project 

      Midgette, Bria; Strunk, Andrew; Akilov, Oleg; Alavi, Afsaneh; Ardon, Christine; Bechara, Falk G.; Cohen, Arnon D.; Cohen, Steven; Daveluy, Steven; del Marmol, Véronique; Delage, Maïa; Esmann, Solveig; Fisher, Shani; Giamarellos-Bourboulis, Evangelos J.; Glowaczewska, Amelia; Goldfarb, Noah; Brant, Elena Gonzalez; Grimstad, Øystein; Guilbault, Sandra; Hamzavi, Iltefat; Hughes, Rosalind; Ingram, John R.; Jemec, Gregor B.E.; Ju, Qiang; Kappe, Naomi; Kirby, Brian; Kirby, Joslyn S.; Lowes, Michelle A.; Matusiak, Lukasz; Micha, Stella; Micheletti, Robert; Miller, Angela P.; Moseng, Dagfinn; Naik, Haley; Nassif, Aude; Nikolakis, Georgios; Paek, So Yeon; Pascual, Jose Carlos; Prens, Errol; Resnik, Barry; Riad, Hassan; Sayed, Christopher; Smith, Saxon D.; Soliman, Yssra; Szepietowski, Jacek C.; Tan, Jerry; Thorlacius, Linnea; Tzellos, Thrasyvoulos; van der Zee, Hessel H.; Villumsen, Bente; Wang, Lanqi; Zouboulis, Christos; Garg, Amit (Journal article; Tidsskriftartikkel, 2022-12-01)
      <p><i>Background</i> Nearly half of patients with hidradenitis suppurativa (HS) report dissatisfaction with their treatment. However, factors related to treatment satisfaction have not been explored. <p><i>Objectives</i> To measure associations between treatment satisfaction and clinical and treatment‐related characteristics among patients with HS. <p><i>Methods</i> Treatment satisfaction was ...
    • Association of lipid-lowering drugs and antidiabetic drugs with age-related macular degeneration: A meta-analysis in Europeans 

      Mauschitz, Matthias M.; Verzijden, Timo; Schuster, Alexander K.; Elbaz, Hisham; Pfeiffer, Norbert; Khawaja, Anthony; Luben, Robert N.; Foster, Paul J.; Rauscher, Franziska G.; Wirkner, Kerstin; Kirsten, Toralf; Jonas, Jost B.; Bikbov, Mukharram M.; Hogg, Ruth; Peto, Tunde; Cougnard-Grégoire, Audrey; Bertelsen, Geir; Erke, Maja Gran; Topouzis, Fotis; Giannoulis, Dimitrios A.; Brandl, Caroline; Heid, Iris M.; Creuzot-Garcher, Catherine P.; Gabrielle, Pierre-Henry; Hense, Hans-Werner; Pauleikhoff, Daniel; Barreto, Patricia; Coimbra, Rita; Piermarocchi, Stefano; Daien, Vincent; Holz, Frank G.; Delcourt, Cecile; Finger, Robert P. (Journal article; Tidsskriftartikkel, 2022-11-07)
      <p><i>Background/aims</i> To investigate the association of commonly used systemic medications with prevalent age-related macular degeneration (AMD) in the general population. <p><i>Methods</i> We included 38 694 adults from 14 population-based and hospital-based studies from the European Eye Epidemiology consortium. We examined associations between the use of systemic medications and any prevalent ...
    • Note to first-year university students: Just do it! In the end, the fact that you study may be more important than how you study. 

      Sæle, Rannveig Grøm; Dahl, Tove I.; Sørlie, Tore; Friborg, Oddgeir (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-20)
      Education is important to society, yet many students do not complete the educations they start. In the present study of 426 students at a Norwegian university, we examined the predictive value of study-related variables with regard to student status one and five years after initial enrollment (stayers versus dropouts). The logistic regression analyses indicated that older students and students who ...
    • Neuroendocrinology of sexual behavior 

      Ågmo, Anders j (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-08)
      One of the consequences of sexual behavior is reproduction. Thus, this behavior is essential for the survival of the species. However, the individual engaged in sexual behavior is rarely aware of its reproductive consequences. In fact, the human is probably the only species in which sexual acts may be performed with the explicit purpose of reproduction. Most human sexual activities as well as sex ...
    • Fødselsrift – hva så? Kvinners vurdering av informasjon om fødselsrift mottatt på barselavdelingen, oppfølgingen de mottar, og betydningen av informasjonen for bekymringer, utfordringer og mestring av fødselsriften de første seks måneder etter fødsel 

      Hortemo, Hedda; Gundersen, Sigrid (Master thesis; Mastergradsoppgave, 2022-03-16)
      Bakgrunn: Kvinner som rammes av en fødselsrift kan ha et udekt informasjonsbehov. Mangel på informasjon kan føre til utfordringer relatert til fysisk og psykisk helse, uavhengig av hvilken grad av rift som er ervervet. Hensikt: Hensikten med studien var å kartlegge kvinners vurdering av informasjonen mottatt om sin fødselsrift på barselavdelingen, erfaringen med oppfølgingen fra helsevesenet ...
    • Sharing food with infants in Hadza communities in Tanzania 

      Abels, Monika; Osokina, Marianna; Kilale, Andrew Martin (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-28)
      By analyzing mealtime interactions of Tanzanian Hadza infants with their interactional partners, we explored how two foundational schemas, namely giving/sharing and autonomy are realized and fostered in infants. We focused on three aspects of the mealtime interactions, namely how the infants’ share was protected, whether independent eating was fostered by the infants’ interactional partners, and ...
    • Stable or unstable associations between learning environment factors, study approaches and exam grades: cross-sectional analyses across two consecutive program years 

      Mygland, Jenny Solveig; Mørk, Gry; Stigen, Linda; Gramstad, Astrid; Magne, Trine A; Bonsaksen, Tore (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-31)
      Studies into the relationships between learning environment perceptions, approaches to studying, and academic outcomes have largely followed cross-sectional designs. As a result, knowledge is sparse with regards to whether, or to what degree, the established associations are consistent across years of study. This study aimed to (i) examine associations between occupational therapy students’ academic ...
    • The mental health consequences on children of the war in Ukraine: A commentary 

      Elvevåg, Brita; DeLisi, Lynn E. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-18)
      The news from Ukraine is currently full of heart-wrenching stories accompanied by graphic images of civilian casualties and massacres that are telecast world-wide on a daily basis. It is hard to fathom the magnitude of the devastation and disruption to regular lives and everyday routines that war brings with it, the witnessing of countless deaths, the associated trauma of living in perpetual fear, ...
    • Plasma levels of platelet-derived microvesicles are associated with risk of future venous thromboembolism 

      Snir, Omri; Wilsgård, line; Latysheva, Nadezhda; Ullsten-Wahlund, Casper; Brækkan, Sigrid Kufaas; Hindberg, Kristian Dalsbø; Hansen, John Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-18)
      Background - Microvesicles (MVs) are small double‐membrane encapsulated particles shed from cells. Case‐control studies have reported elevated plasma levels of platelet‐derived MVs (PDMVs) in patients with venous thromboembolism (VTE). However, it is not known whether high PDMV levels is a risk factor or a consequence of the acute VTE event.<p> <p>Objectives - To investigate the association between ...
    • Joint Effect of Multiple Prothrombotic Genotypes and Mean Platelet Volume on the Risk of Incident Venous Thromboembolism 

      Jakobsen, Lisa; Frischmuth, Tobias; Brækkan, Sigrid Kufaas; Hansen, John Bjarne; Morelli, Vania Maris (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-31)
      Background - A high mean platelet volume (MPV), a marker of increased platelet reactivity, is a risk factor for venous thromboembolism (VTE). Whether established prothrombotic single nucleotide polymorphisms (SNPs) further increase the VTE risk in subjects with high MPV because of biological interaction remains unknown.<p> <p>Aim - To investigate the joint effect of high MPV and prothrombotic ...
    • Association between Carbonic Anhydrase VI (CA VI) gene copy number and dental caries experience 

      Al-Mahdi, Rania Ali Muhsen; Stangvaltaite-Mouhat, Lina; Aleksejuniene, Jolanta; Stankeviciene, Indre; Tømmerås, Berit; Puriene, Alina; Al-Haroni, Mohammed (Journal article; Tidsskriftartikkel; Peer reviewed, 2022)
      The current study examined the association between the carbonic anhydrase VI (CA VI) copy number variations (CNVs) and dental caries experience in adults. In total, 202 of 35-72 years old subjects participating in the Lithuanian National Oral Health Survey (LNOHS) agreed to provide saliva samples, thus their data were included in the current study. Information about sociodemographic, environmental, ...
    • Dental composites - The effects of matrix composition, suboptimal light curing and water exposure 

      Wikant, Aksel (Doctoral thesis; Doktorgradsavhandling, 2023-03-30)
      In Scandinavian countries, resin-based composite materials have been used in restorative dentistry for over 30 years, replacing dental amalgams. Composite materials based on dimethacrylates provide better aesthetics and treatment options. However, according to in-vitro findings, dental composites can be affected by water, potentially reducing the longevity of dental restorations. The proper ...
    • Adolescents’ Assessment of Two Mental Health–Promoting Mobile Apps: Results of Two User Surveys 

      Høgsdal, Helene; Kaiser, Sabine; Kyrrestad, Henriette (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-06)
      To examine the impact of migration and acculturation of Turkish men who have sex with men (MSM) to Germany, using data from the European MSM Internet Survey (EMIS-2010), on measures of acculturation including circumcision status, internalized homonegativity (IH), HIV/STI knowledge, sexual orientation, outness, HIV-testing, and sexual behaviors. We compared four groups of MSM: MSM born and residing ...
    • Impact of Migration and Acculturation on Turkish Men Who Have Sex with Men in Germany: Results from the 2010 European MSM Internet Survey 

      Schmidt, Axel J.; Ross, Michael W.; Berg, Rigmor; Altan, Peyman (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-17)
      To examine the impact of migration and acculturation of Turkish men who have sex with men (MSM) to Germany, using data from the European MSM Internet Survey (EMIS-2010), on measures of acculturation including circumcision status, internalized homonegativity (IH), HIV/STI knowledge, sexual orientation, outness, HIV-testing, and sexual behaviors. We compared four groups of MSM: MSM born and residing ...
    • Should I Stay or Should I Go? The Role of Daily Presenteeism as an Adaptive Response to Perform at Work Despite Somatic Complaints for Employee Effectiveness 

      Rivkin, Wladislaw; Diestel, Stefan; Gerpott, Fabiola H.; Unger, Dana (Journal article; Tidsskriftartikkel; Peer reviewed, 2022)
      Our study seeks to contribute to scholarly understanding of the antecedents and consequences of the crucial, but so far overlooked within-person daily fluctuations in presenteeism. Drawing on theoretical frameworks of presenteeism, which conceptualize presenteeism as an adaptive behavior to deliver work performance despite limitations due to ill-health, we develop a within-person model of daily ...