Sammendrag Et hovedtrekk ved schizofreni ser ut for å være at mennesker med lidelsen ikke engasjerer seg i målrettet atferd i lik grad som friske. Det er pekt på et paradoks om manglende målrettet, samtidig som pasientene godt kan sette pris på hendelser her og nå. Senere år har det kommet til nye metoder, som gir sprikende men likevel lovende funn i retning av at mennesker med schizofreni kan ...

Forskningslitteraturen viser til en dokumentert relasjon mellom traumer og psykose, der forekomsten av traumer er funnet signifikant høyere hos personer med psykose. Til tross for evidensbasert traumebehandling, så er det fortsatt en tendens til at pasientgruppen likevel ikke får denne behandlingsformen. Formålet med litteraturgjennomgangen var å undersøke effekt av evidensbasert traumebehandling ...

Proprioceptive information makes us able to perceive the position of our joints from an internal point of view. In certain cases, proprioceptive information has to be stored in short-term memory, for example, during the learning of new motor skills or the assessment of proprioceptive accuracy. However, there are contradictory findings about the modality-specific storage of proprioceptive information ...

Objectives The aim was to study self-image and the level of psychological symptoms in patients with symptoms attributed to their dental restorative materials.<p><p> Materials and methods A questionnaire containing questions regarding dental and medical history was answered by 257 participants, one group with local oral symptoms only (LSO), and one group with multi-symptoms (M-S). A reference group ...

Triethylene glycol dimethacrylate (TEGDMA) is commonly used in polymer resinbased dental materials. This study investigated the molecular mechanisms of TEGDMA toxicity by identifying its time- and dose-dependent effects on the proteome of human THP-1 monocytes. The effects of different concentrations (0.07– 5 mM) and exposure times (0–72 h) of TEGDMA on cell viability, proliferation, and morphology ...

Study design: This is a double-blind, randomized, placebo-controlled cross-over study of melatonin in complete tetraplegia.<p> <p>Objectives: Tetraplegic patients have an increased risk of venous thrombosis despite prophylaxis, blunted variations in melatonin and altered circadian variation of several hemostatic markers. To examine whether melatonin could modify the regulation of hemostasis, we ...

Background: Results from several cohort and case–control studies suggest a protective association between current alcohol intake and risk of thyroid carcinoma, but the epidemiological evidence is not completely consistent and several questions remain unanswered.<p> <p>Methods: The association between alcohol consumption at recruitment and over the lifetime and risk of differentiated thyroid carcinoma ...

Background: Prospective studies on insulin-like growth factor I (IGF-I) and epithelial ovarian cancer (EOC) risk are inconclusive. Data suggest risk associations vary by tumour characteristics.<p> <p>Methods: We conducted a nested case–control study in the European Prospective Investigation into Cancer and Nutrition (EPIC) to evaluate IGF-I concentrations and EOC risk by tumour characteristics ...

Background: Wound healing problems at the donor site in free abdominal flap breast reconstruction cause significant morbidity to patients. No studies have investigated what impact the use of the internal mammary artery in free abdominal flap breast reconstruction has on abdominal skin perfusion. We hypothesized that harvesting the internal mammary vessels (IMV) has a negative effect on abdominal ...

Autophagy is an evolutionary conserved process by which eukaryotic cells undergo self-digestion of cytoplasmic components. Here we report that a novel Drosophila immunophilin, which we have named Zonda, is critically required for starvation-induced autophagy. We show that Zonda operates at early stages of the process, specifically for Vps34-mediated phosphatidylinositol 3-phosphate (PI3P) deposition. ...