Objectives: The overall aim of this thesis was to investigate different aspects of antibiotic therapy for neonatal sepsis. Material and Methods: The epidemiology of early onset sepsis (EOS) and systemic antibiotic exposure in the first week of life was studied in a nationwide population-based study from the Norwegian Neonatal Network between 2009-2011. A high-dose extended-interval gentamicin ...

Oppvekst i slekt er en praksisform som har lange tradisjoner i den private sfære. Slektsfosterhjem derimot, som kategori og tiltak i barnervernet er et realtivt nytt fenomen. I forskning har oppvekst i og blant slektninger primært blitt utforsket blant antropologer. Med institusjonaliseringen og kategoriseringen av slektsfosterhjem har fenomenet blitt aktuelt også innenfor barnevernrelatert forskning. ...

Myocardial infarction (MI) and stroke rank as the top two killers on the world health organization’s causes of death statistics. Awareness of risk factors is important for targeted prevention of disease, and identification of novel risk factors can further improve the preventive measures. Red cell distribution width (RDW), a measure of the variability in size of the circulating erythrocytes, could ...

Abstract Background Perioperative treatment for common neurosurgical conditions such as chronic subdural hematomas (CSDH) and meningiomas vary. The perioperative period is by definition the time span from 24 hours before surgery until 30 days postoperatively. Even if the surgical treatment in the operation theater can be exactly the same, complication rates differ, and results vary. The aim of ...

The aim of this research project was to improve the knowledge of the people in Northern Norway (the Sami, Kven, and Norwegians) understanding of health, including the use of traditional healing. We conducted 60 semi-structured interviews and 7 focus group interviews. The participants were health personnel, healers, and users of traditional healing. Both the Sami and Norwegians often used traditional ...

It is estimated that 5-10% of breast cancers (BC) and 25% of ovarian cancers (OC) are caused by inherited sequence variants in genes. In the mid 90’s, the two genes BRCA1 and BRCA2 were discovered to be directly associated with increased risk of BC and OC. Molecular screening of these two genes has revealed several disease causing variants as well as variants of unknown clinical significance (VUS). ...

Venous thromboembolism (VTE) is a common disease with an incidence of 1–2 per 1000 individuals. VTE is a collective term for deep vein thrombosis and pulmonary embolism. Extracellular vesicles (EVs) are lipid-membrane-bound spherical vesicles that bud off from the cells upon activation and apoptosis. Their size varies between 30 nm and 1 μm. Recent advances in experimental and observational studies ...

This thesis provides empirical insights about socio-technical interdependencies affecting the making and scaling of an Information Infrastructure (II) for healthcare based on the development of large-scale Electronic Patient Records. The Ph.D. study is an interpretive case study, where the empirical data has been collected from 2012 to 2017. In most developed countries, the pressures from politicians ...

Despite advances in therapies, assessment of fracture risk, and diagnosis of bone fragility, few women and men with high fracture risk receive treatment, even after they develop fracture. To be able to recognize and identify subjects who are at risk for fragility fracture, and to target treatment well, it is important to search for risk factors that are associated with, or ideally, predict fracture. ...

Mange gjennomgår et hjerteinfarkt uten å vite at det har skjedd, dette kalles stumme hjerteinfarkt. Det er ikke kjent hvorfor noen rammes av stumme hjerteinfarkt, mens andre opplever brystsmerter og tar kontakt med lege. I Tromsøundersøkelsens 6.runde ble 6,199 personer undersøkt med EKG, der man kan se om en person har gjennomgått et hjerteinfarkt. I tillegg ble det samlet inn data på smertefølsomhet ...