Doktorgradsavhandlinger (Helsefak): Recent submissions
Now showing items 501-520 of 713
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A study of some biological factors of importance to geriatric psychiatry.
(Doctoral thesis; Doktorgradsavhandling, 2014-09-12)Det er lite kunnskap om vitamin D og sink mangel hos eldre med psykiske lidelser. I en case-control studie fant vi signifikant lavere serum nivå av 25(OH)D i en eldre (>64 år) pasient gruppe sammenlignet med en eldre kontroll gruppe (40.5 nmol/L vs. 65.9 nmol/L). Prevalens av vitamin D mangel (def: 25(OH) D<50 nmol/L) var 71.6% i pasient gruppen mot 20.0% i kontroll gruppen. Det var ikke forskjell ... -
Molecular determinants involved during Staphylococcus aureus colonization and/or infection
(Doctoral thesis; Doktorgradsavhandling, 2014-09-26)Given the link between the compelling impact of Staphylococcus aureus colonization on the risk and outcome of infection, strategies to prevent nasal colonization could be an appealing method of fighting infection. The ability of S. aureus to colonize and infect a host is a balance between its multitudes of virulence factors and the host immune defence mechanisms. Despite the multiple bacterial factors ... -
Investigation of the antiviral effects of artesunate on BK and JC polyomavirus replication
(Doctoral thesis; Doktorgradsavhandling, 2014-09-19)The ubiquitous human BK and JC polyomaviruses cause the diseases polyomavirus-associated nephropathy, hemoragic cystitis and progressive multifocal leukoencephalopathy in immunosuppressed patients. There are no antiviral drugs for these diseases which often lead to kidney graft loss, severe disability and premature death. As a first step in the evaluation of the malaria drug artesunate as a future ... -
Å få og å ta i bruk eit teknisk hjelpemiddel - ei gåtefull reise. Ei kvalitativ undersøking av heimebuande eldre sine erfaringar.
(Doctoral thesis; Doktorgradsavhandling, 2014-09-26)Formidling av tekniske hjelpemiddel er eit hyppig brukt verkty for å gjere eldre i stand til å bu heime så lenge som mogleg. Likevel veit ein lite om korleis eldre erfarer det å få og å ta i bruk tekniske hjelpemiddel. Kunnskap om erfaringane til brukarar av hjelpemiddel kan bidra til ei vidareutvikling av klientsentrerte og effektive helsetenester. Formålet med prosjektet var difor å undersøkje ... -
Aspects of Active Smoking and Breast Cancer
(Doctoral thesis; Doktorgradsavhandling, 2014-10-24)Summary: According to the WHO, breast cancer is by far the most frequently diagnosed cancer, and the most frequent cause of cancer death among women in the world. Tobacco smoking is the single largest cause of cancer worldwide and has been linked to cancer in most organ systems. The aim of this thesis was to illuminate the association between smoking and breast cancer incidence, mortality, and to ... -
Associations of widespread pain sensitivity, comorbid chronic pain and psychological distress with Irritable Bowel Syndrome and abdominal pain
(Doctoral thesis; Doktorgradsavhandling, 2014-09-25)This is the first report documenting widespread hyperalgesia among adolescent and adult individuals with symptoms of IBS in the general population. Results were found to be independent of sex, comorbid pain and psychological distress. Increased pain sensitivity may contribute in triggering and maintaining chronic pain, but prospective studies are needed to examine these possible causal relationships. The ... -
Tumor hypoxia and hypoxic markers in non-small cell lung cancer
(Doctoral thesis; Doktorgradsavhandling, 2014-03-14) -
Cardiovascular adaptation in pregnancy - Effects of angiotensin II, transverse aorta constriction and high-intensity interval training on pregnant rats
(Doctoral thesis; Doktorgradsavhandling, 2014-09-18)Objectives: To investigate how cardiac function, remodeling and gene expression are affected in pregnancy in response to cardiovascular stress, to detect possible adverse effects on the fetus, and to evaluate if coronary endothelial function is influenced by pregnancy and increased cardiac afterload. Methods: Pregnant and non-pregnant rats were subjected to chronic AngII-infusion, transverse aortic ... -
Genetic Susceptibility, Lifestyle, Ovarian Hormones, and Mammographic Density – key factors in breast cancer development. The Norwegian Energy Balance and Breast Cancer Aspects-I Study.
(Doctoral thesis; Doktorgradsavhandling, 2013-02-28)Breast cancer is the most frequent cancer among women worldwide. Over the last century, the prevalence of overnutrition, overweight and obesity has increased, age at menarche has dropped and age at birth of first child has risen among women in Western countries. These trends may be linked to exposure to ovarian hormones that, in turn, may affect a woman’s lifetime risk of getting breast cancer. The ... -
Implementing interventions in adult mental health services to identify and support children of mentally ill parents.
(Doctoral thesis; Doktorgradsavhandling, 2014-03-28)This dissertation is a result of a large-scale longitudinal project (the BAP-study) where the overall aim was to monitor and evaluate the implementation of clinical change to identify and support children of mentally ill parents within the participating clinic. The design includes a pre-test, post-test and one-year follow-up. The first stage of the study involved assessment of the status quo in the ... -
Angiogenic markers as prognostic factors in non-small cell lung cancer (NSCLC)
(Doctoral thesis; Doktorgradsavhandling, 2014-01-31) -
Smoking and incidence and mortality of colorectal cancer
(Doctoral thesis; Doktorgradsavhandling, 2014-06-05)Smoking is one of the most important causes of cancer and premature death worldwide. Two different reports, the most recent monograph published by International Agency for Research on Cancer (IARC) in 2012 and the Unites States Surgeon General’s report of 2014, concluded that smoking is risk factor for both colon and rectal cancer. In addition to being one of the most common cancers in Norway, ... -
Safety of Treatment Provided by Homeopaths Homeopathic Aggravations, Adverse Effects and Risk Assessment
(Doctoral thesis; Doktorgradsavhandling, 2014-03-28)Introduction Homeopathic treatment has a long tradition. Because of its widespread use as alternative therapy in Norway and Europe, but also in nations such as India, investigation into patient safety related to homeopathic treatment is important. Risk in homeopathy can be divided into direct and indirect risk. Direct risk is directly linked to the intervention itself while indirect risk is related ... -
Prognostic markers in oral squamous cell carcinoma
(Doctoral thesis; Doktorgradsavhandling, 2014-06-20)Avhandlingen er basert på 5 artikler. Vi har retrospektivt innhentet klinisk informasjon om 133 pasienter diagnostisert med cancer i munnhulen ved UNN i perioden 1986-2001, og laget Tissue Micro Arrays (TMA) av tumorvev fra de respektive pasientenes svulster. Den første artikkelen er en epidemiologisk beskrivelse av materialet. Artikkel 2 og 3 omfatter ulike potensielle prognostiske markører for ... -
Postoperative insulin resistance and the metabolic and cellular responses to single-dose preoperative oral carbohydrate supplementation – Experimental studies in pigs
(Doctoral thesis; Doktorgradsavhandling, 2014-06-17)Gjennom en serie eksperimentelle studier på gris, inkludert etablering av en målemetode for utvikling av akutt insulinresistens, ble endringer i insulinsensitivitet og i lever- og skjelettmuskelceller undersøkt etter et stort kirurgisk inngrep. Resultatene viser at de cellulære endringene som ledsager utvikling av insulinresistens etter kirurgi har mange likhetstrekk med de endringer man ser ved ... -
e-Rehabilitation: Design and Effectiveness of a Tailored Internet- and Mobile-based Intervention to Support Maintenance of Physical Activity after Cardiac Rehabilitation
(Doctoral thesis; Doktorgradsavhandling, 2014-05-05)Hovedmålet i prosjektet var å tilby en effektiv Internet- og mobiltelefonbasert støtte til opprettholdelse av fysisk aktivitet hos hjerte-kar pasienter etter et rehabiliteringsopphold. For å få laget et godt støtteprogram som både var var effektivt i forhold til å støtte livsstilsending og meningsfullt å bruke ble innspill fra brukerne kombinert med et sterkt teoretisk rammeverk (modeller for ... -
Persistent organic pollutants in human plasma from inhabitants of the Arctic
(Research report; Forskningsrapport, 2003) -
Interpretation of forearm bone mineral density : the Tromsø study
(Doctoral thesis; Doktorgradsavhandling, 2000) -
General practitioner hospitals : use and usefulness : a study from Finnmark County in North Norway.
(Doctoral thesis; Doktorgradsavhandling, 1998) -
The Tromsø study : risk factors for non-vertebral fractures in a middle-aged population
(Doctoral thesis; Doktorgradsavhandling, 1999)