Doktorgradsavhandlinger (Helsefak): Recent submissions

Now showing items 1-20 of 725

    • Differences in risk of venous thromboembolism in men and women 

      Arnesen, Carl Arne Løchen (Doctoral thesis; Doktorgradsavhandling, 2024-11-22)
      Venous thromboembolism (VTE) is a common and potentially deadly disease that affects men and women, but studies on sex-specific risk have been inconsistent. Some studies have reported a higher risk in men, others in women. It has also been suggested that men have a higher inherent risk of VTE than women when reproductive factors (pregnancy and estrogen use) are accounted for. Furthermore, the ...

    • Mental Health Problems, General Health and Dropout in Upper Secondary School in Northern Norway: A prospective cohort study and a qualitative exploration of the dropout process 

      Goll, Charlotte Bjørnskov (Doctoral thesis; Doktorgradsavhandling, 2024-11-22)
      Health and socioeconomic inequalities are heavily correlated, and poor mental health increases the risk of exclusion from the labour market. Education is important to equalize the socioeconomic gradient, and completing upper secondary school is essential. The high dropout rates in upper secondary school are therefore of high concern. The main project “Ung vilje” was a prospective cohort study started ...

    • Neonatal risk factors for hearing impairment 

      Hemmingsen, Dagny Elise (Doctoral thesis; Doktorgradsavhandling, 2024-11-01)
      Hearing impairment (HI) is a prevalent childhood disability with significant public health implications, impacting language and developmental outcomes if not early identified and managed. While illness in the neonatal period is a recognized risk factor for HI, less is known about the specific impacts of the different, and often interrelated morbidities and invasive treatments in neonatal intensive ...

    • Maternal death and maternal morbidity in Georgia 

      Skhvitaridze, Natia (Doctoral thesis; Doktorgradsavhandling, 2024-10-25)
      Maternal death (MD) and morbidity are indicators for maternal health and healthcare system development. This PhD project aimed to investigate MD, maternal morbidity, and related risk factors in Georgia using data from the Georgian Birth Registry (GBR) and digital health surveillance systems. Paper I, with a case series design, identified direct and indirect causes of MD from 2014 to 2017. Paper ...

    • Child-Inclusive Mandatory Family Mediation in Norway: A sociocultural exploration of children’s participation 

      Grape, Lovise (Doctoral thesis; Doktorgradsavhandling, 2024-10-11)
      <p><i>Introduction:</i> Family mediation should help separating parents make agreements that attend to the best interest of the child. Children can be included in this process. The aim of this dissertation is to explore the practise of child-inclusive family mediation in Norway on three interdependent planes: a personal, an interpersonal, and a cultural and institutional plane. These planes follow ...

    • Nordic diet and mortality: The Norwegian Women and Cancer study 

      Jensen, Torill (Doctoral thesis; Doktorgradsavhandling, 2024-10-10)
      <p><i>Background:</i> Noncommunicable diseases (NCDs) such as cancer and cardiovascular diseases (CVDs) are predominant causes of mortality in Norwegian women. With a national goal to reduce premature mortality from NCDs by 33% by 2030, Norway is also committed to achieving Sustainable Development Goals, including those related to climate change. The Food and Agriculture Organization (FAO) emphasizes ...

    • Group-based mentoring in undergraduate medical education 

      Skjevik, Elise Pauline Paulsen (Doctoral thesis; Doktorgradsavhandling, 2024-09-27)
      This thesis focuses on group mentorship for undergraduate medical students as a pivotal element in fostering a supportive and collaborative learning environment, essential for the complex field of medicine. Previous studies have mostly focused on one-on-one mentoring. Group mentorships can foster a collaborative and reflective environment in which students can benefit from the collective knowledge ...

    • Treatment and prevention of neonatal sepsis 

      Bjerkhaug, Aline Uhirwa (Doctoral thesis; Doktorgradsavhandling, 2024-09-20)
      Worldwide, the incidence of neonatal sepsis is estimated at around 3000 cases per 100,000 live births, accompanied by a mortality rate of 17.6%. Group B streptococcus (GBS) is globally the leading cause of newborn infections. The global burden of neonatal sepsis and invasive GBS disease is skewed towards the low-income countries, but the outcome of invasive GBS disease with massive inflammation can ...

    • Adhesion mechanisms and bacteriocins in Staphylococcus haemolyticus - New targets for the prevention and treatment of infections 

      Wolden, Runa (Doctoral thesis; Doktorgradsavhandling, 2024-09-13)
      <i>Staphylococcus haemolyticus</i> er ein bakterie med mange eigenskapar. Han finst naturleg i mikrobiotaen vår, men kan også vere opportunistisk patogen. Evna til å danne biofilm, unngå immunsystemet og motstå antibiotikabehandling gjer at behandling er utfordrande. Målet med avhandlinga var å utvide forståinga av virulensfaktorar og bakteriosinproduksjon hos bakterien for å finne betre måtar å ...

    • Activity-Based Protein Profiling (ABPP) and functional validation of uncharacterized enzymes in bacterial pathogens Staphylococcus aureus and Klebsiella pneumoniae 

      Uddin, Md Jalal (Doctoral thesis; Doktorgradsavhandling, 2024-08-30)
      <i>Staphylococcus aureus</i> and <i>Klebsiella pneumoniae</i> often reside in the human body as harmless commensal bacteria but can cause various infections once they breach the host's immune defenses. These pathogens are increasingly difficult to treat due to the emergence of antibiotic-resistant strains such as methicillin-resistant <i>S. aureus</i> (MRSA) and carbapenem-resistant <i>K. pneumoniae</i>. ...

    • Integrating Pharmacists in Emergency Departments: Exploring Key Factors for Future Physician-Pharmacist Collaboration 

      Johnsgård, Tine (Doctoral thesis; Doktorgradsavhandling, 2024-08-30)
      Medication-related problems pose a significant burden to patients and healthcare services, especially during transitions of care, such as moving from home to the emergency department (ED). Based upon the knowledge that up to 80% of medication lists in hospitals contain discrepancies upon hospital admission and that approximately 20% of admissions are medication-related, the "Pharmacist in the Emergency ...

    • User Satisfaction in Child and Adolescent Mental Health Services: Validating the Norwegian version of the Experience of Service Questionnaire and investigating predictors and associations. A conceptual model of user satisfaction in Child and Adolescent Mental Health Services 

      Arnesen, Yngvild (Doctoral thesis; Doktorgradsavhandling, 2024-08-15)
      The primary aim of this thesis is to address the knowledge gap concerning user satisfaction with Child and Adolescent Mental Health Services (CAMHS) from the perspectives of young people and their parents. The objectives are threefold: (1) establish the construct validity of the Experience of Service Questionnaire (ESQ) (Paper I), assess the predictors of user satisfaction (Paper II), and explore ...

    • Forensic DNA phenotyping - Towards reliable and accurate DNA tests for prediction of eye colour, hair colour and biogeographical ancestry 

      Salvo, Nina Mjølsnes (Doctoral thesis; Doktorgradsavhandling, 2024-06-27)
      Forensic DNA phenotyping (FDP) can aid police investigations where there is no match between the crime scene DNA and a suspect or a database hit. By using FDP, we can predict appearance and biogeographical ancestry (BGA) of an unknown person. These DNA tests are currently being implemented in forensic casework in many countries. However, prior to implementation, the methods have to be evaluated and ...

    • The perception of the menstrual cycle, cycle-related symptoms, and hormonal contraception in female endurance athletes: The FENDURA project 

      Engseth, Tina Pettersen (Doctoral thesis; Doktorgradsavhandling, 2024-06-18)
      <p><i>Background:</i> The current understanding of the menstrual cycle (MC) and hormonal contraceptive (HC) use in female athletes is scarce and the impact on training, performance, and recovery is inconclusive. Still, many athletes perceive MC/HC use and related symptoms to interfere with training, performance, and recovery. However, as most previous studies often include athletes from multiple ...

    • Activity Profiles and Training Loads of Highly Trained Female Football Players 

      Winther, Andreas Kjæreng (Doctoral thesis; Doktorgradsavhandling, 2024-06-27)
      Avhandlingen undersøkte kamp- og treningsbelastning hos kvinnelige fotballspillere på toppnivå i Norge. Ved å samle data fra fire Toppserien lag over to sesonger, analyserte vi spillernes aktivitetsnivå i kamp og i typiske treningsuker. Resultatene avslørte store forskjeller i aktivitet mellom ulike spillerposisjoner, spesielt med tanke på høyhastighetsløp og sprinter. Videre kom det frem at ...

    • Intracranial artery disease in the general population 

      Johnsen, Liv-Hege (Doctoral thesis; Doktorgradsavhandling, 2024-06-18)
      Intracranial aneurysms (IAs) and intracranial artery stenoses (ICAS) are vascular conditions of the brain that can lead to stroke. An IA is an outpouching of the artery wall that can rupture, causing an aneurysmal subarachnoid hemorrhage (aSAH), a severe form of stroke with high mortality and potential for disability. ICAS involves narrowing of brain arteries, commonly due to atherosclerosis, which ...

    • Exploring Staphylococcus aureus Adaptation in In vitro Colonization and Infection Models: A Transcriptomics Approach 

      Bastakoti Belbase, Srijana (Doctoral thesis; Doktorgradsavhandling, 2024-06-14)
      Individuals colonized by <i>S. aureus</i>, face a higher risk of <i>S. aureus</i> infections compared to non-carriers, and some throat carriers are prone to recurrent colonization even after antibiotic treatment. While <i>S. aureus</i> nasal colonization is well-studied, there is limited information about throat colonization. Our research aims to address this knowledge gap by exploring <i>S. aureus</i> ...

    • From student to professional – mastering the necessary non-technical skills. Assessment tools and effects of multi-professional simulation training 

      Prydz, Katrine (Doctoral thesis; Doktorgradsavhandling, 2024-06-14)
      Non-technical skills include important skills such as communication, decision making, situational awareness and teamwork. Together with medical knowledge, these constitute the basic competence that all doctors must possess. This thesis takes a closer look at Norwegian medical students' non-technical skills. This thesis consists of three articles. In the first article, the necessary non-technical ...

    • Long non-coding RNAs in ulcerative colitis 

      Ray, Mithlesh Kumar (Doctoral thesis; Doktorgradsavhandling, 2024-06-12)
      Ulcerative colitis (UC) is a chronic inflammatory condition of the large intestine, influenced by various factors such as genetics, environment, gut contents, and the host's immune system. It has been reported that epigenetic factors, such as long non-coding RNAs (lncRNAs) and DNA methylation, play a role in UC development. The contribution of lncRNAs to UC pathogenesis is not fully understood. ...

    • Encouraging participation in physical activity for individuals with intellectual disability: motivational factors, barriers, and mHealth applications 

      Michalsen, Henriette (Doctoral thesis; Doktorgradsavhandling, 2024-06-11)
      This thesis focuses on participation in physical activity among adults with intellectual disabilities. The aim is to explore motivation, the use of mobile health applications, and identify barriers to participation in physical activity. The thesis sought to understand why some individuals engage in physical activity while others do not, and how technology can help increase activity levels. In the ...