Now showing items 201-220 of 713

    • Suicide among Sámi – Cultural meanings of suicide and interventions for suicide prevention in Nordic parts of Sápmi 

      Stoor, Jon Petter Anders (Doctoral thesis; Doktorgradsavhandling, 2020-12-17)
      <p><i>Background:</i> In suicidological research, it is well known that suicide rates differ, sometimes to a great extent, between countries, sexes, religious and ethnic populations. It has been suggested that in-depth exploration of social, cultural, contextual and historical perspectives on suicide is needed to explain this, and increase efficacy of prevention efforts. Sámi are the Indigenous ...
    • Perinatal mortality and its association with antenatal care utilization in the Republic of Georgia 

      Manjavidze, Tinatin (Doctoral thesis; Doktorgradsavhandling, 2020-12-11)
      <p><i>Background:</i> Despite recent achievements, perinatal mortality (PM) rates remain high worldwide, especially in low-income countries (>30 per 1000 births). PM is defined as the death of a fetus/livebirth between 22 completed weeks of gestation and the first 7 days of life. Simple, non-invasive interventions could reduce PM rates, since most deaths are caused by preventable conditions. Adequate ...
    • Arctic food biographies. An ethnographic study of food and health in everyday life of elderly Arctic women 

      Kvitberg, Trine (Doctoral thesis; Doktorgradsavhandling, 2020-12-04)
      <p>The aim of the ethnographic study described was to listen sensitively and give voice to elderly Arctic women’s personal food biographies and everyday experiences of living in small coastal towns and inland areas of Norway’s Circumpolar North, North West Russia and Greenland. These specified geographical contexts were selected because they have been the focus of the Arctic and Global Health research ...
    • A Shotgun-metagenomics approach for laboratory diagnostics in clinical microbiology 

      Sanabria-Moreno, Adriana Maria (Doctoral thesis; Doktorgradsavhandling, 2020-11-12)
      Shotgun-metagenomics (SMg) has a huge potential, particularly in clinical microbiology where conventional diagnostic methods have limitations such as diagnosis of prosthetic joint infection (PJI). The main objective of this project was to explore the use of SMg in clinical diagnostics of PJI directly from blood culture bottles (BCBs) inoculated with PJT specimens. First, we assessed the use of a ...
    • Dietary intake of marine polyunsaturated fatty acids and incidence, recurrence and mortality related to venous thromboembolism 

      Isaksen, Trond (Doctoral thesis; Doktorgradsavhandling, 2020-11-27)
      Venøs tromboembolisme (VTE) er en fellesbetegnelse på dyp venetrombose (DVT) og lungeemboli (LE). VTE er en vanlig og alvorlig karsykdom hvor forekomsten har vært svakt økende de siste årene. Marine omega-3 fettsyrer (n-3 PUFAs) har flere gunstige effekter på hemostasemekanismen. Målet med denne doktorgradsavhandlingen var å undersøke sammenhengen mellom inntak av marine n-3 PUFAs i kosten og risikoen ...
    • Sexual function and lifestyle behavior among lymphoma survivors after high dose chemotherapy with autologous stem-cell transplantation 

      Bersvendsen, Hanne Skjerven (Doctoral thesis; Doktorgradsavhandling, 2020-10-22)
      <p><i>Background/Aims:</i> Lymphoma is one of the most prevalent malignancies among young persons. The survival rate is high, though comes with a risk of late effects including secondary cancer, cardiovascular disease (CVD) and chronic fatigue (CF). Some lymphoma patients require especially intensive treatment, high dose chemotherapy with autologous stem-cell transplantation (auto-SCT), to achieve ...
    • The Metabolome and Lipidome of Ulcerative Colitis 

      Diab, Joseph (Doctoral thesis; Doktorgradsavhandling, 2020-10-09)
      The two major forms of Inflammatory bowel disease (IBD), Ulcerative Colitis (UC) and Crohn’s Disease (CD), are characterized by a dysregulated mucosal immune response triggered by several genetic and environmental factors in the context of host-microbe interaction. This overwhelming complexity makes IBD ideal for metabolomic studies to unravel the disease pathobiology and to improve the patient ...
    • Prognostic indicators of survival for patients with oral cavity squamous cell carcinoma in Norway. Outcomes in a retrospective, multicenter cohort, with special focus on oral tongue squamous cell carcinoma, 2005-2009 

      Bjerkli, Inger-Heidi (Doctoral thesis; Doktorgradsavhandling, 2020-10-08)
      Oral cavity cancer (OCC) is the most frequent of head and neck cancers, most being squamous cell carcinomas (SCC). Within the oral cavity, the oral tongue is the most common site of cancer. These cancers are very aggressive, with poor survival. The treatment decision is based upon classifications of tumor (T), lymph node (N), and metastasis (M), although tumors with the same classification may act ...
    • Telemedicine in remote orthopaedic consultations: A randomised controlled trial 

      Buvik, Astrid Synnøve (Doctoral thesis; Doktorgradsavhandling, 2020-09-25)
      Decentralised services using outreach clinics or modern technology are methods to reduce the patient burden by reducing transport time and costs to the health care system. The aim of this study was to evaluate the quality of planned remote orthopaedic consultations with the help of videoconferences. From 2007 to 2012, we performed a randomised controlled trial (RCT) with two parallel groups: ...
    • The Temporomandibular Joint in Juvenile Idiopathic Arthritis, focusing on Quality of Life, Oral Microbiome and Intervention 

      Frid, Paula (Doctoral thesis; Doktorgradsavhandling, 2020-10-02)
      The temporomandibular joint (TMJ) is commonly involved in juvenile idiopathic arthritis (JIA), and may lead to impaired mouth opening, pain and facial growth disturbances. Asymptomatic TMJ arthritis may be diagnosed late in the disease course, thus management is challenging. The overall objectives of this thesis were to provide new knowledge on quality of life (QoL), the oral microbiome and interventions ...
    • Surgical treatment of stress urinary incontinence in women. The shift from Burch colposuspension to the retropubic tension-free vaginal tape procedure 

      Holdø, Bjørn (Doctoral thesis; Doktorgradsavhandling, 2020-09-25)
      Until the late 1990s, the Burch colposuspension was considered the gold standard for the surgical treatment of stress urinary incontinence (SUI) and stress-dominated mixed urinary incontinence (MUI) in women. In 1996, Ulmsten introduced the minimally invasive retropubic tension-free vaginal tape (TVT) procedure, and the first case series reported high safety and effectiveness of this procedure at ...
    • Medical case reports: Some theoretical and empirical perspectives 

      Nissen, Trygve (Doctoral thesis; Doktorgradsavhandling, 2020-09-18)
      The medical case report (CR) is one of the oldest medical genres and it is still popular among clinicians. At the end of the 20th century medical journals gave priority to research articles with more advanced study designs. Following the advent of online publishing, a high number of CRs are now being published. We identify the various merits and limitations of the CR genre. Two important merits are ...
    • Terrains of Uncertainty. Communicative Challenges of Medically Unexplained Illness in Youth 

      Østbye, Silje Vagli (Doctoral thesis; Doktorgradsavhandling, 2020-09-29)
      Persistent bodily symptoms without medical clarity creates many layers of uncertainty both for health professionals and for patients. In primary care, research has shown that clinical encounters of medically unexplained symptoms (MUS) are highly contentious, sometimes causing adverse effects. However, little is known about communicative challenges for adolescents in specialist health care settings; ...
    • Patients' and therapists’ experiences with a new treatment for eating disorders, combining physical exercise and dietary therapy. An interview study 

      Bakland, Maria (Doctoral thesis; Doktorgradsavhandling, 2020-09-24)
      Eating disorders (EDs) are mental disorders were effective treatment may be essential for a good outcome. Previous research has shown that physical exercise and dietary therapy (PED-t) may alleviate symptoms of bulimia nervosa (BN) and binge ED (BED). The aim of this study was to explore experiences with the PED-t. We interviewed 10 therapists and 20 women who participated and analysed the transcribed ...
    • Merkel Cell Polyomavirus and Merkel Cell Carcinoma 

      Rasheed, Kashif (Doctoral thesis; Doktorgradsavhandling, 2020-09-04)
      Merkel cell carcinoma (MCC) is a rare, highly aggressive neuroendocrine skin cancer. More than 80% of MCC have Merkel cell polyomavirus (MCPyV) clonally integrated into the human genome (VP-MCC) while the remaining 20% are virus negative (VN-MCC) but linked with chronic exposure to UV sunlight. MCC is particularly associated with immune suppression with 8-48 folds increase in incidence in immunosuppressive ...
    • Understanding the Neural and Behavioral Correlates of Mind Wandering Through Transcranial Direct Current Stimulation 

      Boayue, Nya Mehnwolo (Doctoral thesis; Doktorgradsavhandling, 2020-08-28)
      The mind’s tendency to wander is an integral part of the human experience. Recent studies suggest that high-level cognitive functions such as mind wan- dering (MW) can be modulated by non-invasive brain stimulation (NIBS) techniques such as transcranial direct current stimulation (tDCS). However, the effectiveness of tDCS in the cognitive domain remains an issue of debate. This thesis aimed to ...
    • Trauma radiology in northern Norway 

      Bågenholm, Anna (Doctoral thesis; Doktorgradsavhandling, 2020-08-27)
      <p><i>Background: </i>This thesis focuses on diagnostic imaging in potentially severely injured patients admitted to the University Hospital of North Norway. Imaging is important for timely initiation of treatment and survival after trauma. The use of standardized whole body computer tomography (SWBCT) is increasing. However, the ionizing radiation used may cause a small risk for induction of cancer ...
    • Clinical characteristics, echocardiographic indices of heart failure and mortality in a general population. The Tromsø Study 

      Stylidis, Michael (Doctoral thesis; Doktorgradsavhandling, 2020-08-21)
      <p><i>Background - </i>Ageing of the general population, declining incidence of myocardial infarction (MI) and improvements in medical treatment have resulted in an increase in heart failure (HF) prevalence. At the same time, number of studies linked to all-cause mortality and HF, co-existing HF and chronic obstructive pulmonary disease (COPD) are scarce. <p><i>Objective - </i>To study long-term ...
    • Physical activity and mental distress among adolescents. Results from the Tromsø Study: Fit Futures 

      Opdal, Ida Marie (Doctoral thesis; Doktorgradsavhandling, 2020-08-21)
      The onset of experiencing symptoms of mental distress, such as depression and anxiety, is most common during the adolescent years, and is concurrent with a measured decrease in physical activity levels. Research on the association between physical activity and mental distress among adolescents find contradictory results, and the field is in need of more longitudinal research with validated measurements. ...
    • Adverse events as a measure of patient safety in cancer care 

      Haukland, Ellinor Christin (Doctoral thesis; Doktorgradsavhandling, 2020-09-11)
      “First, do no harm” is a fundamental element of health care and considered indistinguishable from the delivery of quality in health care. While cancer care has become more effective, it has also become more complex consequently increasing the risk for harm. We have assessed the extent and severity of treatment related adverse events in hospitalised cancer patients and elucidated how adverse events ...