Viser treff 381-400 av 713

    • Overweight, body size perceptions, lifestyle changes and health concerns in young adults. The Tromsø Study, Fit Futures . A combined approach using qualitative interviews and a population-based cross-sectional study 

      Sand, Anne-Sofie (Doctoral thesis; Doktorgradsavhandling, 2017-10-13)
      The aims of this thesis were to expand our knowledge on overweight issues including motivation and obstacles for weight management in the young, and especially the female population. Late adolescence and early adulthood are important stages of life regarding lifestyle habits. There has been a lack of research into environmental determinants of food choices, physical activity and body size perceptions ...
    • The role of Staphylococcus aureus in allergic disease and cross-reactivity in fish allergy 

      Sørensen, Martin (Doctoral thesis; Doktorgradsavhandling, 2017-09-29)
      Aims: The aims was to describe prevalence`s of allergic disease in adolescents and study associations between allergic diseases and Staphylococcus aureus. Secondly, to study cross-reactivity in fish allergic children and the utility of existing and novel tests for fish allergy. Material and Methods: Prevalence of allergic diseases and associations to Staphylococcus aureus was studied in a cross-sectional ...
    • Uric acid - its role as a risk factor for the metabolic syndrome, cardiovascular and kidney disease 

      Storhaug, Hilde (Doctoral thesis; Doktorgradsavhandling, 2016-12-06)
      Uric acid as a potential risk factor for cardiovascular and renal conditions has gained renewed attention. In this work we aimed to assess the associations between serum uric acid, metabolic syndrome, hypertension, renal dysfunction, cardiovascular events and mortality. In paper I, 6083 participants from Tromsø 4 were stratified according to body mass index. Endpoints were the metabolic syndrome ...
    • Maternal Anti-HLA Class I Antibodies in Connection with Pregnancy and Neonatal Thrombocytopenia – a Cause for Concern? Clinical Characteristics and Antibody Analysis of Retrospective and Prospective Populations 

      Dahl, Jesper (Doctoral thesis; Doktorgradsavhandling, 2017-09-08)
      Background: Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is caused by maternal antibodies that target fetal platelets during pregnancy. It can occur when fetal platelets express a paternally-inherited antigen that is not shared by the mother. Maternal antibodies that cause FNAIT are directed against human platelet antigens (HPAs) on fetal platelets, and the resulting fetal/ neonatal ...
    • Speaking in behalf of the person with dementia in home-based care. A qualitative study of collaboration between formal and family caregivers in Sami and Norwegian municipalities. 

      Larsen, Lill Sissel Sverresdatter (Doctoral thesis; Doktorgradsavhandling, 2017-09-08)
      Studien «Speaking on behalf of the person with dementia in home-based care» viser en rekke krevende barrierer for samhandling i demensomsorg i norske kommuner. Disse barrierene har negativ påvirkning på hvilke hjelpetilbud som tilbys og hvordan familier nyttiggjør seg disse, noe som igjen har betydning for oppnåelse av helsepolitiske mål og pasientrettigheter. I kommuner med både norsk og samisk ...
    • Semantic and Perceptual Models for Clinical Decision Support Systems 

      Marco Ruiz, Luis (Doctoral thesis; Doktorgradsavhandling, 2017-05-05)
      The current vision of healthcare is evolving in directions towards the secondary use of health data for producing new evidence, rapidly assimilating new knowledge, including the patient as an active component in decision-making and developing communication strategies to coordinate different areas of health care, among others. The work in these directions heavily relies on the appropriate use of ...
    • Self-reported musculoskeletal complaints. Prevalence, risk factors, and mortality. 

      Andorsen, Ole Fredrik Linnemann (Doctoral thesis; Doktorgradsavhandling, 2017-06-30)
      This thesis used data from the large-scale population-based Tromsø Study. More than 45,000 inhabitants of the municipality of Tromsø participated in at least one of the seven surveys conducted between 1974 and 2016 (Tromsø 1-7). In the papers constituting this thesis, musculoskeletal complaints (MSCs) were defined as having pain and/or stiffness in muscles and joints lasting for at least 3 months ...
    • Caregivers to patients with severe traumatic brain injury. A national prospective study on caregiver burden, life satisfaction and health care experiences. 

      Manskow, Unn Sollid (Doctoral thesis; Doktorgradsavhandling, 2017-02-24)
      Background: Severe traumatic brain injury (TBI) is a major public health challenge as it often has huge consequences for the patient and the family for a long time after the injury. Objective: Assess caregiver burden and predictors of burden 1year post injury, investigate change and stability of caregiver burden and life satisfaction over time. Develop a validated tool to assess family member’s ...
    • The effect of hypoxaemia on fetal cardiac function 

      Bhide, Amarnath (Doctoral thesis; Doktorgradsavhandling, 2017-08-01)
      Objectives The objectives were 1. To study the effect of placental embolisation as well as maternal hypoxaemia on fetal left and right ventricular function as reflected by pulsed-wave Doppler-derived myocardial performance index (MPI). 2. To study myocardial systolic and diastolic function of the fetal left and right ventricles using ultrasound speckle tracking technique to measure global strain ...
    • “Breaking the silence” Interpersonal violence and Health among Sami and non-Sami. A population-based study in Mid -and Northern Norway 

      Eriksen, Astrid Margrethe Anette (Doctoral thesis; Doktorgradsavhandling, 2017-06-16)
      Sammendrag Dette arbeidet er en del av SAMINOR 2 studien. SAMINOR 2 er en populasjonsbasert tversnittsundersøkelse av helse- og levekår i områder med både norsk og samisk bosetning i Midt- og Nord-Norge. SAMINOR 2 er delvis en oppfølging av SAMINOR 1, men ble utvidet til å inkludere flere helserelaterte tema som vold og symptomer på post-traumatisk stress (PTS). I utvalgte områder ble alle innbyggere ...
    • Calanus oil and its lipid constituents - Impact on obesity and obesity-related metabolic disorders in rodents 

      Höper, Anje Christina (Doctoral thesis; Doktorgradsavhandling, 2014-02-26)
      Fedme er et økende helseproblem, og spesielt er avleiring av bukfett forbundet med økt risiko for en rekke sykdommer. Kosttilskudd med omega-3 fettsyrer har vist positive effekter på fedme-relaterte sykdommer. Calanusolje er et relativt nytt produkt som produseres fra raudåte (Calanus finmarchicus) som finnes i store mengder i norske farvann. Oljen har lavt innhold av miljøgifter og er rik på ...
    • Venous thromboembolism and cancer 

      Gran, Olga Vikhammer (Doctoral thesis; Doktorgradsavhandling, 2017-06-27)
      Venous thromboembolism (VTE) is a collective term for deep vein thrombosis and pulmonary embolism. VTE is a common cause of mortality and morbidity in patients with cancer, and may also be the first sign of an underlying malignancy. The first aim of this thesis was to investigate the risk of incident and recurrent VTE in active cancer compared to a cancer-free reference population and to explore the ...
    • Systematic reporting of pre-hospital major incident medical management - identifying needs, a suggested solution and assessing implementation 

      Fattah, Sabina (Doctoral thesis; Doktorgradsavhandling, 2017-06-16)
      Storulykker er krevende for prehospitale medisinske tjenester over hele verden. Vi vet at de samme problemene viser seg gang på gang. Hvordan kan de prehospitale tjenestene lære av tidligere erfaringer? På grunn av storulykkers (engelsk: major incidents) omfattende betydning for menneskeliv og samfunn er det nødvendig å standardisere rapporteringen fra hendelsene. Dette kan muliggjøre analyser ...
    • The prognostic impact of immune-related markers in non-small cell lung cancer 

      Hald, Sigurd Mathiesen (Doctoral thesis; Doktorgradsavhandling, 2017-06-15)
      Lung cancer is the leading cancer killer worldwide and non-small cell lung cancer (NSCLC) is the predominant subtype of lung cancer. The immune system plays an important role in cancer development. Immune-related markers expressed in the tumor microenvironment of resection specimens predict prognosis in many cancers, and may be potential targets for therapy. We aimed to characterize the expression ...
    • Interaction and mutuality in physical therapy for preterm infants and their parents 

      Håkstad, Ragnhild Barclay (Doctoral thesis; Doktorgradsavhandling, 2017-06-15)
      In Norway, PTs in the municipalities deliver family-centered services to preterm infants and their parents. In addition to the prevention, detection and treatment of motor impairments, PTs are expected to educate parents and help them adapt to life with a preterm infant. In this doctoral project, we investigated physical therapy for preterm infants and their parents during the first year post-hospital ...
    • Endocrine-related factors and risk of venous thromboembolism 

      Lerstad, Gunhild (Doctoral thesis; Doktorgradsavhandling, 2017-05-31)
      Even though many environmental and inherited predisposing factors have been associated with venous thromboembolism (VTE), still 30–50% of the events have no obvious provoking factors. There is limited knowledge concerning the association between endocrine-related factors and VTE risk. Therefore we aimed to investigate the relation between hyperglycemia, thyroid function, vitamin D, calcium, ...
    • Wound healing in diabetes. An intervention study in db/db mice 

      Berdal, Margrete (Doctoral thesis; Doktorgradsavhandling, 2017-06-09)
      The prevalence of diabetes is increasing globally. Certain microvascular and macrovascular complications such as cardiovascular disease, retinopathy, nephropathy, neuropathy, and impaired wound healing are associated with the disease. Prolonged exposure to hyperglycaemia plays an important role in their development. Glucose reacts with macromolecules including proteins, lipoproteins, and nucleic ...
    • Bidirectional association between arterial and venous thrombosis 

      Lind, Caroline (Doctoral thesis; Doktorgradsavhandling, 2017-06-22)
      Venous thromboembolism (VTE), a collective term for deep vein thrombosis (DVT) and pulmonary embolism (PE), has been considered a separate disease from arterial cardiovascular diseases (CVD, i.e. myocardial infarction (MI) and ischemic stroke). However, recent studies have proposed an association between VTE and arterial CVD. The aim of the thesis was to investigate this association in a general ...
    • Incipient changes in ICU patients’ clinical conditions – signs, nurses’ assessment and the dialogue between nurses and physicians 

      Kvande, Monica Evelyn (Doctoral thesis; Doktorgradsavhandling, 2017-06-09)
      Providing safe care for patients in intensive care units (ICUs) requires both awareness and perception of the signs indicating changes in a patient’s condition at an early stage. In addition, ensuring high-quality health care and patient safety in the ICU requires an effective exchange of patient information among health professionals. The overall aims of this study were to explore the phenomenon ...
    • Uric acid and adiponectin in cardiovascular disease 

      Norvik, Jon Viljar (Doctoral thesis; Doktorgradsavhandling, 2017-04-20)
      Uric acid, a product of metabolism, was discovered a quarter of a millennium ago and has been known to be a possible cardiovascular risk factor for well over a century. A much newer discovery, adiponectin, was discovered only a little more than 20 years ago as a protein hormone secreted by adipose tissue and has attracted substantial attention for its association with cardiovascular disease. This ...