Artikler, rapporter og annet (medisinsk biologi): Recent submissions

Now showing items 621-640 of 1059

    • The genome sequence of Atlantic cod reveals a unique immune system 

      Star, Bastiaan; Nederbragt, Alexander Johan; Jentoft, Sissel; Grimholt, Unni; Malmstrøm, Martin; Gregers, Tone Fredsvik; Rounge, Trine Ballestad; Paulsen, Jonas; Solbakken, Monica Hongrø; Sharma, Animesh; Wetten, Ola Frang; Lanzén, Anders; Winer, Roger; Knight, James; Vogel, Jan-Hinnerk; Aken, Bronwen; Andersen, Øivind; Lagesen, Karin; Tooming-Klunderud, Ave; Edvardsen, Rolf; Kirubakaran, G. Tina; Espelund, Mari; Nepal, Chirag; Previti, A. Christopher; Karlsen, Bård Ove; Moum, Truls; Skage, Morten; Berg, Paul Ragnar; Gjøen, Tor; Kuhl, Heiner; Thorsen, Jim; Malde, Ketil; Reinhardt, Richard; Du, Lei; Johansen, Steinar Daae; Searle, Steve; Lien, Sigbjørn; Nilsen, Frank; Jonassen, Inge; Omholt, Stig W; Stenseth, Nils Christian; Jakobsen, Kjetill Sigurd (Journal article; Tidsskriftartikkel; Peer reviewed, 2011-08-10)
      Atlantic cod (Gadus morhua) is a large, cold-adapted teleost that sustains long-standing commercial fisheries and incipient aquaculture1, 2. Here we present the genome sequence of Atlantic cod, showing evidence for complex thermal adaptations in its haemoglobin gene cluster and an unusual immune architecture compared to other sequenced vertebrates. The genome assembly was obtained exclusively by 454 ...

    • Multifaktorielle sykdommer i norsk lakseoppdrett. Sluttrapport 

      Johansen, Lill-Heidi; Bang-Jensen, Berit; Jansen, Mona Dverdal; Taksdal, Torunn; Krasnov, Aleksei (Research report; Forskningsrapport, 2015-07-02)
      Prosjektet «Multifaktorielle sykdommer i norsk lakseoppdrett» er utført i et samarbeid mellom Nofima, Veterinærinstituttet, AquaGen AS og Patogen AS. Hovedmålet for prosjektet var å øke kunnskapen om utviklingen av multifaktorielle sykdommer ved å vurdere effekten av ulike variabler og deres interaksjon. Effekten av ulike variabler (genetisk resistens mot IPN, IPNV bærer status, IPNV reaktivering ...

    • A survey of dioxin-like contaminants in fish from recreational fishing. 

      Heimstad, Eldbjørg Sofie; Grønstøl, Gaute; Hetland, Karl Torstein; Alarcon, Javier Martinez; Rylander, Charlotta; Mariussen, Espen (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-07-19)
      The dioxin and dioxin-like compounds are regarded as one of the most toxic group of environmental contaminants. Food for the commercial market is regularly monitored for their dioxin levels and the concentration allowed in food is strictly regulated. Less is known about locally caught fish from recreational fishing, which is often brought home for consumption. This can be fish caught from nearby ...

    • Temperature during early development has long-term effects on microRNA expression in Atlantic cod 

      Bizuayehu, Teshome Tilahun; Johansen, Steinar D; Puvanendran, Velmurugu; Toften, Hilde; Babiak, Igor (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-04-17)
      Background: Environmental temperature has serious implications in life cycle of aquatic ectotherms. Understanding the molecular mechanisms of temperature acclimation and adaptation of marine organisms is of the uttermost importance for ecology, fisheries, and aquaculture, as it allows modeling the effects of global warming on population dynamics. Regulatory molecules are major modulators of acclimation ...

    • Detection of Anaplasma phagocytophilum in Ixodes ricinus ticks from Norway using a realtime PCR assay targeting the Anaplasma citrate synthase gene gltA 

      Henningsson, Anna J.; Hvidsten, Dag; Kristiansen, Bjørn Erik; Matussek, Andreas; Stuen, Snorre; Jenkins, Andrew (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-08-01)
      Background: A TaqMan real-time PCR assay targeting the Anaplasma citrate synthase gene, gltA, was developed and used for detection of Anaplasma phagocytophilum in 765 Ixodes ricinus ticks collected from dogs and cats in northern Norway (n = 669) and Telemark county in southern Norway (n = 96). Results: Among the ticks from northern Norway the prevalence of A. phagocytophilum was 3.0 %, while the ...

    • Investigating the mobilome in clinically important lineages of Enterococcus faecium and Enterococcus faecalis 

      Mikalsen, Theresa; Pedersen, Torunn Annie; Willems, Rob J; Coque, Teresa M.; Werner, Guido; Sadowy, Eva; van Schaik, Willem; Jensen, Lars Bogø; Sundsfjord, Arnfinn; Hegstad, Kristin (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-04-10)
      Background: The success of Enterococcus faecium and E. faecalis evolving as multi-resistant nosocomial pathogens is associated with their ability to acquire and share adaptive traits, including antimicrobial resistance genes encoded by mobile genetic elements (MGE). Here, we investigate this mobilome in successful hospital associated genetic lineages, E. faecium sequence type (ST)17 (n=10) and ...

    • Intracellular MMP-2 Activity in Skeletal Muscle is Associated with Type II Fibers 

      Hadler-Olsen, Elin Synnøve; Solli, Ann Iren; Hafstad, Anne Dragøy; Winberg, Jan-Olof; Uhlin-Hansen, Lars (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-09-29)
      Matrix metalloproteinase 2 (MMP-2) is a proteolytic enzyme implicated in motility, differentiation, and regeneration of skeletal muscle fibers through processing of extracellular substrates. Although MMP-2 has been found to be localized intracellularly in cardiomyocytes where the enzyme is thought to contribute to post-ischemic loss of contractility, little is known about intracellular MMP-2 activity ...

    • Comprehensive molecular, genomic and phenotypic analysis of a major clone of Enterococcus faecalis MLST ST40 

      Zischka, Melanie; Künne, Carsten T.; Blom, Jochen; Wobser, Dominique; Sakιnç, Türkân; Schmidt-Hohagen, Kerstin; Dabrowski, P. Wojtek; Nitsche, Andreas; Hübner, Johannes; Hain, Torsten; Chakraborty, Trinad; Linke, Burkhard; Goesmann, Alexander; Voget, Sonja; Daniel, Rolf; Schomburg, Dietmar; Hauck, Rüdiger; Hafez, Hafez M.; Tielen, Petra; Jahn, Dieter; Solheim, Margrete; Sadowy, Ewa; Larsen, Jesper; Jensen, Lars Bogø; Ruiz-Garbajosa, Patricia; Pérez, Dianelys Quiñones; Mikalsen, Theresa; Bender, Jennifer; Steglich, Matthias; Nübel, Ulrich; Witte, Wolfgang; Werner, Guido (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-03-12)
      Background: Enterococcus faecalis is a multifaceted microorganism known to act as a beneficial intestinal commensal bacterium. It is also a dreaded nosocomial pathogen causing life-threatening infections in hospitalised patients. Isolates of a distinct MLST type ST40 represent the most frequent strain type of this species, distributed worldwide and originating from various sources (animal, human, ...

    • Complete mitochondrial genome sequences of the Arctic Ocean codfishes Arctogadus glacialis and Boreogadus saida reveal oriL and tRNA gene duplications 

      Breines, Ragna; Ursvik, Anita; Nymark, Marianne; Johansen, Steinar; Coucheron, Dag-Hugo (Journal article; Tidsskriftartikkel; Peer reviewed, 2008-05-27)
      We have determined the complete mitochondrial genome sequences of the codWshes Arctogadus glacialis and Boreogadus saida (Order Gadiformes, Family Gadidae). The 16,644 bp and 16,745 bp mtDNAs, respectively, contain the same set of 37 structural genes found in all vertebrates analyzed so far. The gene organization is conserved compared to other Gadidae species, but with one notable exception. ...

    • Whole-genome sequencing reveals clonal expansion of multiresistant Staphylococcus heamolyticus in European hopsitals 

      Cavanagh, Jorunn Pauline; Hjerde, Erik; Holden, Matthew T.G.; Kahlke, Tim; Klingenberg, Claus; Flægstad, Trond; Parkhill, J; Bentley, Stephen D; Sollid, Johanna U Ericson (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)

    • Levonorgestrel-impregnated intrauterine device as treatment for endometrial hyperplasia: A national multicentre randomised trial 

      Ørbo, Anne; Vereide, Anne Beate; Arnes, Marit; Pettersen, Inger; Straume, Bjørn (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)

    • Fish consumption and mortality in the European Prospective Investigation into Cancer and Nutrition cohort 

      Engeset, Dagrun; Braaten, Tonje; Teucher, Birgit; Kuhn, Tilman; Bueno-de-Mesquita, HB; Leenders, Max; Agudo, Antonio; Bergmann, Manuela M; Valanou, Elisavet; Naska, Androniki; Trichopoulou, Antonia; Key, Timothy J; Crowe, Francesca L; Overvad, Kim; Sonestedt, Emily; Mattiello, Amalia; Peeters, Petra H; Wennberg, Maria; Jansson, Jan Håkan; Boutron-Ruault, Marie-Christine; Dossus, Laure; Dartois, Laureen; Li, Kuanrong; Barricarte, Aurelio; Ward, Heather; Riboli, Elio; Agnoli, Claudia; Huerta, Jose Maria; Sanchez, Maria-Jose; Tumino, Rosario; Altzibar, Jone M; Vineis, Paolo; Masala, Giovanna; Ferrari, Pietro; Muller, David C; Johansson, Mattias; Luisa Redondo, M; Tjønneland, A; Olsen, Anja; Olsen, Karina Standahl; Brustad, Magritt; Skeie, Guri; Lund, Eiliv (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)

    • Estimating QUALY gains in applied studies: A review of cost-utility analyses published in 2010 

      Wisløff, Torbjørn; Hagen, Gunhild; Hamidi, Vida; Movik, Espen; Klemp, Marianne; Olsen, Jan Abel (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)

    • Complete regression and systemic protective immune responses obtained in B16 melanomas after treatment with LTX-315 

      Camilio, Ketil André; Berge, Gerd; Ravuri, Chandra Sekhar; Rekdal, Øystein; Sveinbjørnsson, Baldur (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)

    • Low FEV1, smoking history, and obesity are factors associated with oxygen saturation decrease in an adult population cohort 

      Vold, Monica Linea; Aasebø, Ulf; Melbye, Hasse (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)

    • Midwives’ Adherence to Preoperative Care Guidelines Prior to Emergency Caesarean Section at Bwaila Maternity Hospital in Malawi 

      Mwale, Ruth; Maluwa, Alfred; Malata, Address; Odland, Jon Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)

    • Interobserver Reliability of Four Diagnostic Methods Using Traditional Korean Medicine for Stroke Patients 

      Lee, Ju Ah; Ko, Mi Mi; Kang, Byoung-Kab; Alræk, Terje; Birch, Stephen; Lee, Myeong S. (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)

    • Clinical phenotype associations with various types of anti-dsDNA antibodies in patients with recent onset of rheumatic symptoms. Results from a multicentre observational study 

      Compagno, Michele; Rekvig, Ole Petter; Bengtsson, Anders; Sturfeld, Gunnar; Heegaard, Niels H. H.; Jönsen, Andreas; Jacobsen, Rasmus S.; Eilertsen, Gro Østli; Fenton, Christopher Graham; Truedsson, Lennart; Nossent, Johannes C; Jacobsen, Søren (Journal article; Tidsskriftartikkel, 2014)

    • High levels of multiresistance in quinolone resistant urinary tract isolates of Escherichia coli from Norway; a non clonal phenomen? 

      Strand, Linda; Jenkins, Andrew; Henriksen, Ingrid Høgli; Allum, Anne-Gry; Grude, Nils; Kristiansen, Bjørn-Erik (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)

    • Predictors of ICS/LABA prescribing in COPD patients: A study from general practice 

      Drivenes, Elin; Østrem, Anders; Melbye, Hasse (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)