Viser treff 741-760 av 1059

    • The VEGF- and PDGF-family of angiogenic markers have prognostic impact in soft tissue sarcomas arising in the extremities and trunk 

      Kilvær, Thomas Karsten; Smeland, Eivind; Valkov, Andrey Yurjevich; Sørbye, Sveinung Wergeland; Bremnes, Roy M.; Busund, Lill-Tove; Dønnem, Tom (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
      Background: Soft-tissue sarcomas are rare malignant tumors of mesenchymal lineage that can arise in any part of the body. Prognosis, and hence also treatment may vary according to histologic subtype and localization. Angiogenesis is the process of forming new blood vessels from pre-existing ones. The deregulation of this process is thought to be an important step in malignant transformation. This ...
    • Reducing the risk of complementary and alternative medicine (CAM):Challenges and priorities 

      White, Adrian; Boon, Heather; Alræk, Terje; Lewith, George; Liu, Jian Ping; Norheim, Arne Johan; Steinsbekk, Aslak; Yamashita, Hitoshi; Fønnebø, Vinjar (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Introduction: The safety of health care is increasingly prominent concern of the public, applying to complementary and alternative medicine (CAM) as well as conventional treatment. In 2009, a group of academic and clinical CAM researchers held a workshop to discuss the constraints and priorities of research into CAM safety. This group here report their discussions, and offer collaboration with ...
    • Breastfeeding as a Specific Value in Women's Lives: The Experiences and Decisions of Breastfeeding Women 

      Lööf-Johanson, Margaretha; Foldevi, Mats; Rudebeck, Carl Edvard (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background: Worldwide, breastfeeding is recommended for every woman who gives birth to a child. The propensity to breastfeed varies. There is considerable knowledge about the experiences and circumstances that affect the decision to breastfeed, but knowledge about what actually generates the decision’s force still needs to be increased. The aim of this study was to gain knowledge of how the ...
    • Why some women fail to give birth at health facilities: a qualitative study of women's perceptions of perinatal care from rural Southern Malawi 

      Kumbani, Lily C; Bjune, Gunnar Aksel; Chirwa, Ellen; Malata, Address; Odland, Jon Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background: Despite Malawi government’s policy to support women to deliver in health facilities with the assistance of skilled attendants, some women do not access this care. Objective: The study explores the reasons why women delivered at home without skilled attendance despite receiving antenatal care at a health centre and their perceptions of perinatal care. Methods: A descriptive study ...
    • The hazards of death by smoking in middle-aged women 

      Gram, Inger Torhild; Sandin, Sven; Braaten, Tonje; Lund, Eiliv; Weiderpass, Elisabete (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Recent studies have found that the risk of death continues to increase among female smokers, as compared with women who have never smoked. We wanted to examine the effect of smoking on all-cause and causespecific mortality and calculate the corresponding population attributable fraction (PAF) of mortality in the Norwegian women and cancer study; a nationally representative prospective cohort ...
    • Cancer incidence and mortality in Chukotka, 1997–2010 

      Dudarev, AA; Chupakhin, Valery; Odland, Jon Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Objectives. The general aim was to assess cancer incidence and mortality among the general population of Chukotka in 1997 2010 and to compare it with the population of Russia. Methods. Cancer data were abstracted from the annual statistical reports of the P.A. Hertzen Research Institute of Oncology in Moscow. The annual number and percent of cases, crude and age-standardized cancer incidence ...
    • Occupational health and health care in Russia and Russian Arctic: 1980–2010 

      Dudarev, Alexy A.; Odland, Jon Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background. There is a paradox in Russia and its Arctic regions which reports extremely low rates of occupational diseases (ODs), far below those of other socially and economically advanced circumpolar countries. Yet, there is widespread disregard for occupational health regulations and neglect of basic occupational health services across many industrial enterprises. Study design and methods. ...
    • Health and society in Chukotka: an overview 

      Dudarev, AA; Chupakhin, Valery; Odland, Jon Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      This study provides a historical overview of the changes in the socio-economic and health status of the population of Chukotka, from the Soviet to the post-Soviet period, with special attention paid to the circumstances of indigenous people. Past health studies in Chukotka are reviewed and key demographic and health indicator data presented. Since the 1990s, Chukotka’s population has shrunk to ...
    • Occupational accidents in Russia and the Russian Arctic 

      Dudarev, AA; Karnachev, Igor P; Odland, Jon Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background. According to official statistics, the rate of occupational accidents (OAs) and fatal injuries in Russia decreased about 5-fold and 2-fold, respectively, from 1975 to 2010, but working conditions during this period had the opposite trend; for example, the number of people who work in unfavourable and hazardous conditions (particularly since 1991) has increased significantly. Methods. ...
    • Occupational diseases in Murmansk Oblast: 1980–2010 

      Dudarev, Alexy A.; Talykova, LV; Odland, Jon Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background. Official statistics tend to underestimate the incidence of occupational disease (OD) nationally and regionally in Russia. Objectives. The general aim was to obtain an accurate estimate of ODs in Murmansk Oblast in 1980 2010 and to determine the rate of specific types of ODs among cohorts of workers who had been exposed to the hazardous factors causing the disease. Materials and ...
    • Self-rated health among Greenlandic Inuit and Norwegian Sami adolescents: associated risk and protective correlates 

      Spein, Anna Rita; Pedersen, Cecilia P; Silviken, Anne Cathrine; Melhus, Marita; Kvernmo, Siv; Bjerregaard, Peter (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Objectives. Self-rated health (SRH) and associated risk and protective correlates were investigated among two indigenous adolescent populations, Greenlandic Inuit and Norwegian Sami. Design. Cross-sectional data were collected from ‘‘Well-being among Youth in Greenland’’ (WBYG) and ‘‘The Norwegian Arctic Adolescent Health Study’’ (NAAHS), conducted during 2003 2005 and comprising 10th and 11th ...
    • Why do women prefer home births in Ethiopia? 

      Shiferaw, Solomon; Spigt, Marcus; Godefrooij, Merijn; Melkamu, Yilma; Tekie, Michael (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background: Skilled attendants during labor, delivery, and in the early postpartum period, can prevent up to 75% or more of maternal death. However, in many developing countries, very few mothers make at least one antenatal visit and even less receive delivery care from skilled professionals. The present study reports findings from a region where key challenges related to transportation and ...
    • Climate change and the potential effects on maternal and pregnancy outcomes: an assessment of the most vulnerable - the mother, fetus, and newborn child 

      Rylander, Charlotta; Odland, Jon Øyvind; Sandanger, Torkjel Manning (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      In 2007, the Intergovernmental Panel on Climate Change (IPCC) presented a large amount of evidence about global warming and the impact of human activities on global climate change. The Lancet Commission have identified a number of ways in which climate change can influence human health: lack of food and safe drinking water, poor sanitation, population migration, changing disease patterns and ...
    • Persistent Organic Pollutants in Norwegian Men from 1979 to 2007: Intraindividual Changes, Age–Period–Cohort Effects, and Model Predictions 

      Nøst, Therese Haugdahl; Breivik, Knut; Fuskevåg, Ole-Martin; Nieboer, Evert; Odland, Jon Øyvind; Sandanger, Torkjel Manning (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background: Longitudinal monitoring studies of persistent organic pollutants (POPs) in human populations are important to better understand changes with time and age, and for future predictions. Objectives: We sought to describe serum POP time trends on an individual level, investigate age–period–cohort effects, and compare predicted polychlorinated biphenyl (PCB) concentrations to measured values. ...
    • Indicators of food and water security in an Arctic Health context - results from an international workshop discussion 

      Nilsson, Lena Maria; Berner, James; Dudarev, Alexey A.; Mulvad, Gert; Odland, Jon Øyvind; Parkinson, Alan; Rautio, Arja; Tikhonov, Constantine; Evengård, Birgitta (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      In August 2012, a literature search with the aim of describing indicators on food and water security in an Arctic health context was initialized in collaboration between the Arctic Human Health Expert Group, SDWG/AHHEG and the AMAP (Arctic Monitoring and Assessment Programme within the Arctic Council) Human Health Assessment Group, AMAP/HHAG. In December 2012, workshop discussions were performed ...
    • B4GALT family mediates the multidrug resistance of human leukemia cells by regulating the hedgehog pathway and the expression of p-glycoprotein and multidrug resistance-associated protein 1 

      Zhou, Humin; Ma, Hongye; Wei, Wei; Ji, Donghua; Song, Xiaobo; Sun, Jinglu; Zhang, Jianing; Jia, Li (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      b-1, 4-Galactosyltransferase gene (B4GALT) family consists of seven members, which encode corresponding enzymes known as type II membrane-bound glycoproteins. These enzymes catalyze the biosynthesis of different glycoconjugates and saccharide structures, and have been recognized to be involved in various diseases. In this study, we sought to determine the expressional profiles of B4GALT family ...
    • Trans-Ethnic Fine-Mapping of Lipid Loci Identifies Population-Specific Signals and Allelic Heterogeneity That Increases the Trait Variance Explained 

      Wu, Y; Waite, LL; Jackson, Anne U.; Sheu, WHH; Buyske, Steven; Absher, D; Arnett, DK; Boerwinkle, E; Bonnycastle, LL; Carty, CL; Cheng, I; Cochran, B; Croteau-Chonka, DC; Dumitrescu, L; Eaton, CB; Franceschini, N; Guo, XQ; Henderson, BE; Hindorff, LA; Kim, E; Kinnunen, L; Komulainen, P; Lee, WJ; Le Marchand, L; Lin, Y; Lindstrom, J; Holmen, Oddgeir; Mitchell, SL; Narisu, N; Robinson, JG; Schumacher, F; Stancaakovaa, A; Sundvall, J; Sung, YJ; Swift, AJ; Wang, WC; Wilkens, L; Wilsgaard, Tom; Young, AM; Adair, LS; Ballantyne, CM; Buzkova, P; Chakravarti, A; Collins, FS; Duggan, D; Feranil, AB; Ho, LT; Hung, YJ; Hunt, SC; Hveem, Kristian; Juang, JMJ; Kesaniemi, AY; Kuusisto, J; Laakso, M; Lakka, TA; Lee, IT; Leppert, MF; Matise, TC; Moilanen, L; Njølstad, Inger; Peters, U; Quertermous, T; Rauramaa, R; Rotter, JI; Saramies, J; Tuomilehto, J; Uusitupa, M; Wang, TD; Boehnke, M; Haiman, CA; Chen, YDI; Kooperberg, C; Assimes, TL; Crawford, DC; Hsiung, CA; North, KE; Mohlke, Karen L. (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Genome-wide association studies (GWAS) have identified ~ 100 loci associated with blood lipid levels, but much of the trait heritability remains unexplained, and at most loci the identities of the trait-influencing variants remain unknown. We conducted a trans-ethnic fine-mapping study at 18, 22, and 18 GWAS loci on the Metabochip for their association with triglycerides (TG), high-density ...
    • Macronutrient composition of the diet and prospective weight change in participants of the EPIC-PANACEA study 

      Vergnaud, Anne-Claire; Norat, Teresa; Mouw, Traci; Romaguera, Dora; May, Anne M.; Bueno-de-Mesquita, H. Bas; van der A, Daphne; Agudo, Antonio; Wareham, Nicholas; Khaw, Kay-Tee; Romieu, Isabelle; Freisling, Heinz; Slimani, Nadia; Perquier, Florence; Boutron-Ruault, Marie-Christine; Clavel-Chapelon, Françoise; Palli, Domenico; Berrino, Franco; Mattiello, Amalia; Tumino, Rosario; Ricceri, Fulvio; Rodriguez, Laudina; Molina-Montes, Esther; Amiano, Pilar; Barricarte, Aurelio; Chirlaque, Maria-Dolores; Crowe, Francesca L.; Orfanos, Philippos; Naska, Androniki; Trichopoulou, Antonia; Teucher, Birgit; Kaaks, Rudolf; Boeing, Heiner; Buijsse, Brian; Johansson, Ingegerd; Hallmans, Göran; Drake, Isabel; Sonestedt, Emily; Jakobsen, Marianne Uhre; Overvad, Kim; Tjønneland, Anne; Halkjær, Jytte; Skeie, Guri; Braaten, Tonje; Lund, Eiliv; Riboli, Eilo; Peeters, Petra H.M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background: The effect of the macronutrient composition of the usual diet on long term weight maintenance remains controversial. Methods: 373,803 subjects aged 25–70 years were recruited in 10 European countries (1992–2000) in the PANACEA project of the EPIC cohort. Diet was assessed at baseline using country-specific validated questionnaires and weight and height were measured at baseline and ...
    • A Long-Term Low-Frequency Hospital Outbreak of KPC-Producing Klebsiella pneumoniae Involving Intergenus Plasmid Diffusion and a Persisting Environmental Reservoir 

      Tofteland, Ståle; Naseer, Mohammed Umaer; Lislevand, Jan Helge; Sundsfjord, Arnfinn; Samuelsen, Ørjan (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background: To study the molecular characteristics of a long-term, low frequency outbreak of blaKPC-2 in a low prevalence setting involving the hospital environment. Methodology/Principal Findings: KPC-producing bacteria were screened by selective chromogenic agar and Real-Time PCR. The presence of antibiotic resistance genes was ascribed by PCRs and subsequent sequencing, and the KPC-producing isolates ...
    • Dissemination of a Carbapenem-Resistant Acinetobacter baumannii Strain Belonging to International Clone II/Sequence Type 2 and Harboring a Novel AbaR4-Like Resistance Island in Latvia 

      Saule, Mara; Samuelsen, Ørjan; Dumpis, Uga; Sundsfjord, Arnfinn; Karlsone, Aija; Balode, Arta; Miklasevics, Edvins; Karah, Nabil (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      An outbreak of hospital-acquired Acinetobacter baumannii infections, caused by a blaOXA-23-positive carbapenem-resistant strain belonging to international clone II/ST2, was detected in Latvia. The strain was partially equipped with the armA gene and the intI1-aacA4-catB8-aadA1-qacE 1 class 1 integron. In addition, the strain carried AbaR25, a novel AbaR4-like resistance island of 46,500 bp ...