Artikler, rapporter og annet (medisinsk biologi): Nye registreringer

Viser treff 901-920 av 1059

    • Concentrations and geographical variations of selected toxic elements in meat from semi-domesticated reindeer (Rangifer tarandus tarandus L.) in Mid- and Northern Norway : evaluation of risk assessment 

      Hassan, Ammar Ali; Brustad, Magritt; Sandanger, Torkjel Manning (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Meat samples (n = 100) from semi-domesticated reindeer (Rangifer tarandus tarandus L.) were randomly collected from 10 grazing districts distributed over four Norwegian counties in 2008 and 2009. The main aim was to study concentrations and geographical variations in selected toxic elements; cadmium (Cd), lead (Pb), arsenic (As), copper (Cu), nickel (Ni) and vanadium (V) in order to assess the risk ...

    • Criterion validity of a 10-category scale for ranking physical activity in Norwegian women 

      Borch, Kristin Benjaminsen; Ekelund, Ulf; Brage, Søren; Lund, Eiliv (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Accurate measurement of physical activity (PA) is critical to establish dose-response relationships with various health outcomes. We compared the self-administered PA questionnaire from the Norwegian Women and Cancer Study (NOWAC) with a criterion method in middle-aged Norwegian women. A sample of 177 randomly recruited healthy women attended two clinical visits approximately 4-6 months apart. At ...

    • The development of severe Neonatal Alloimmune Thrombocytopenia due to Anti-HPA-1a Antibodies is correlated to maternal ABO genotypes 

      Ahlen, Maria Therese; Husebekk, Anne; Killie, Mette Kjær; Kjeldsen-Kragh, Jens; Olsson, Martin L.; Skogen, Bjørn Ragnar (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Background. Maternal alloantibodies against HPA-1a can cross placenta, opsonize foetal platelets, and induce neonatal alloimmune thrombocytopenia (NAIT). In a study of 100, 448 pregnant women in Norway during 1995–2004, 10.6% of HPA-1a negative women had detectable anti-HPA-1a antibodies. Design and Methods. A possible correlation between the maternal ABO blood group phenotype, or underlying genotype, ...

    • Unemployment and disability pension-an 18-year follow-up study of a 40-year-old population in a Norwegian county 

      Støver, Morten; Pape, Kristine; Johnsen, Roar; Fleten, Nils; Sund, Erik Reidar; Claussen, Bjørgulf; Bjørngaard, Johan Håkon (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      This study explored the association of unemployment and an increased risk of receiving disability pension, and the possibility that this risk is attributed to municipality-specific characteristics. A cohort of 7,985 40-42 year olds was followed for 18 years in national registers, identifying new episodes of unemployment and cases of disability pension. The association between an unemployment period ...

    • Autocrine Prostaglandin E-2 Signaling Promotes Tumor Cell Survival and Proliferation in Childhood Neuroblastoma 

      Rasmuson, Agnes; Kock, Anna; Fuskevåg, Ole-Martin; Kruspig, Björn; Simon-Santamaria, Jaione; Gogvadze, Vladimir; Johnsen, John Inge; Kogner, Per; Sveinbjørnsson, Baldur (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Prostaglandin E2 (PGE2) is an important mediator in tumor-promoting inflammation. High expression of cyclooxygenase-2 (COX-2) has been detected in the embryonic childhood tumor neuroblastoma, and treatment with COX inhibitors significantly reduces tumor growth. Here, we have investigated the significance of a high COX-2 expression in neuroblastoma by analysis of PGE2 production, the expression pattern ...

    • Any difference? : use of a CAM provider among cancer patients, coronary heart disease (CHD) patients and individuals with no cancer/CHD 

      Kristoffersen, Agnete Egilsdatter; Norheim, Arne Johan; Fønnebø, Vinjar (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Background: Although use of complementary and alternative medicine (CAM) among cancer patients has been described previously, prevalence of use has not commonly been compared to other disease groups in a true population sample where CAM use or cancer is not the main focus. The aims of the present study are to (1) examine how CAM use in cancer patients differs from people with a previous CHD diagnosis ...

    • The third helix of the homeodomain of paired class homeodomain proteins acts as a recognition helix both for DNA and protein interactions 

      Bruun, Jack-Ansgar; Thomassen, Ernst I.s.; Kristiansen, Kurt; Tylden, Garth Daryl; Holm, Turid; Mikkola, Ingvild; Bjørkøy, Geir; Johansen, Terje (Journal article; Tidsskriftartikkel; Peer reviewed, 2005)
      The transcription factor Pax6 is essential for the development of the eyes and the central nervous system of vertebrates and invertebrates. Pax6 contains two DNA-binding domains; an N-terminal paired domain and a centrally located homeodomain. We have previously shown that the vertebrate paired-less isoform of Pax6 (Pax6ΔPD), and several other homeodomain proteins, interact with the full-length ...

    • Drug resistance is widespread among children who receive long-term antiretroviral treatment at a rural Tanzanian hospital 

      Bratholm, Clara Sofie; Johannessen, Asgeir; Naman, Ezra; Gundersen, Svein Gunnar; Kivuyo, Sokoine; Holberg-Petersen, Mona; Ormaasen, Vidar; Bruun, Johan N (Journal article; Tidsskriftartikkel; Peer reviewed, 2010)
      To assess long-term virological efficacy and the emergence of drug resistance in children who receive antiretroviral treatment (ART) in rural Tanzania. Haydom Lutheran Hospital has provided ART to HIV-infected individuals since 2003. From February through May 2009, a cross-sectional virological efficacy survey was conducted among children (<15 years) who had completed ≥6 months of first-line ...

    • Aneuploidy prediction and tumor classification with heterogeneous hidden conditional random fields 

      Barutcuoglu, Z; Airoldi, EM; Dumeaux, vanessa; Schapire, RE; Troyanskaya, Olga (Journal article; Tidsskriftartikkel; Peer reviewed, 2009)
      The heterogeneity of cancer cannot always be recognized by tumor morphology, but may be reflected by the underlying genetic aberrations. Array comparative genome hybridization (array-CGH) methods provide high-throughput data on genetic copy numbers, but determining the clinically relevant copy number changes remains a challenge. Conventional classification methods for linking recurrent alterations ...

    • Comparative effectiveness of antihypertensive medication of primary prevention of cardiovascular disease : systematic review and multiple treatments meta-analysis 

      Fretheim, Atle; Odgaard-Jensen, Jan; Brørs, Odd; Madsen, Steinar; Njølstad, Inger; Norheim, Ole Frithjof; Svilaas, Arne B; Thürmer, Hanne; Flottorp, Signe (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      We conducted a systematic review of evidence from randomized controlled trials to answer the following research question: What are the relative effects of different classes of antihypertensive drugs in reducing the incidence of cardiovascular disease outcomes for healthy people at risk of cardiovascular disease? We searched MEDLINE, EMBASE, AMED (up to February 2011) and CENTRAL (up to May 2009), ...

    • Prevalence of vertebral fractures in women and men in the population-based Tromsø Study 

      Waterloo, Svanhild Haugnes; Ahmed, Luai A.; Center, Jacqueline; Eisman, John A.; Morseth, Bente; Nguyen, Nguyen D.; Nguyen, Tuan; Søgaard, Anne Johanne; Emaus, Nina (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Osteoporotic vertebral fractures are, as the hip fractures, associated with increased morbidity and mortality. Norway has one of the highest reported incidences of hip fractures in the world. Because of methodological challenges, vertebral fractures are not extensively studied. The aim of this population based study was to describe, for the first time, the age- and sex specific occurrence of ...

    • Differential expression patterns of conserved miRNAs and isomiRs during Atlantic halibut development 

      Bizuayehu, Teshome; Lanes, Carlos Fredrico Ceccon; Furmanek, Tomasz; Karlsen, Bård Ove; Fernandes, Jorge; Johansen, Steinar; Babiak, Igor (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      MicroRNAs (miRNAs) play a major role in animal ontogenesis. Size variants of miRNAs, isomiRs, are observed along with the main miRNA types, but their origin and possible biological role are uncovered yet. Developmental profiles of miRNAs have been reported in few fish species only and, to our knowledge, differential expressions of isomiRs have not yet been shown during fish development. Atlantic ...

    • The effect of different feeding regimes on enzyme activities of gut microbiota in Atlantic cod (Gadus morhua L.) 

      Askarian, Fatemeh; Sperstad, Sigmund; Merrifield, Daniel L; Arun Kumar, Ray; Ringø, Einar (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      The aims of this study were: (1) evaluate enzyme-producing bacteria isolated from the GI tract of Atlantic cod, (2) identify the most promising enzyme-producing bacteria by 16S rRNA gene sequencing and (3) to assess whether these bacteria have the ability to inhibit in vitro growth of four well known pathogenic bacteria; Aeromonas salmonicida subsp. salmonicida, V. (L.) anguillarum, Moritella viscosa ...

    • Culturable autochthonous gut bacteria in Atlantic salmon (Salmo salar L.) fed diets with or without chitin. Characterization by 16S rRNA gene sequencing, ability to produce enzymes and in vitro growth inhibition of four fish pathogens 

      Askarian, Fatemeh; Zhou, Zhigang; Olsen, Rolf Erik; Sperstad, Sigmund; Ringø, Einar (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      The present investigation evaluated the effect of chitin (5% supplementation) on the adherent aerobic intestinal microbiota of Atlantic salmon (Salmo salar L.). One hundred and seventy three isolates were isolated but 34 isolates died prior to positive identification. Sixty four out of 139 autochthonous gut bacteria were further identified by 16S rRNA gene sequencing and further tested for protease, ...

    • HPV mRNA test in primry screening of women 20-34 years 

      Sørbye, Sveinung Wergeland; Fismen, Silje; Gutteberg, Tore Jarl; Mortensen, Elin Synnøve; Skjeldestad, Finn Egil (Conference object; Konferansebidrag, 2011)

    • Vaksine og screening : ja takk, begge deler! 

      Sørbye, Sveinung Wergeland (Journal article; Tidsskriftartikkel, 2010-01-21)
      - I Norge trenger vi ikke velge mellom HPV-vaksine eller screening. Vi har råd til begge deler.

    • Støtter dansk HPV-praksis 

      Sørbye, Sveinung Wergeland (Chronicle; Kronikk, 2012-02-13)
      Danskene har en fornuftig praksis når kvinner med lette celleforandringer blir undersøkt med en spesifikk HPV mRNA test i stedet for umiddelbar kolposkopi og biopsi.

    • Redegjør for HPV-resultater 

      Sørbye, Sveinung Wergeland; Fismen, Silje; Gutteberg, Tore Jarl; Mortensen, Elin Synnøve (Chronicle; Kronikk, 2011-01-25)
      Fire Tromsø-leger tilbakeviser kritikk fra Bergen-professor om at de har oversolgt resultater fra sin studie om HPV-testing. De redegjør for hvordan de har fulgt opp kvinner med usikre celleforandringer.

    • Patolog slår tilbake mot gynekologer 

      Sørbye, Sveinung Wergeland (Chronicle; Kronikk, 2011-12-12)
      Antallet tilfeller av livmorhalskreft er stabilt i Norge, men har gått ned ved de fem sykehusene som har brukt den RNA-baserte HPV-testen, hevder patolog Sveinung Wergeland Sørbye.

    • Ny generasjon HPV-tester på vent 

      Sørbye, Sveinung Wergeland; Gutteberg, Tore Jarl; Vintermyr, Olav Karsten (Chronicle; Kronikk, 2010-09-18)
      Ny forskning viser at gentester for humant papillomvirus (HPV) siler ut de behandlingstrengende i langt større grad enn celleprøver. Samtidig er det grunn til å tro at mRNA-tester bør velges fremfor DNA-tester.