Artikler, rapporter og annet (medisinsk biologi): Nye registreringer

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    • Use of complementary and alternative medicine at Norwegian and Danish hospitals 

      Salomonsen, Laila Johansdatter; Skovgaard, Lasse; La Cour, Søren; Nyborg, lisbeth; Launsø, Laila; Fønnebø, Vinjar (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Several studies have found that a high proportion of the population in western countries use complementary and alternative medicine (CAM). However, little is known about whether CAM is offered in hospitals. The aim of this study was to describe to what extent CAM is offered in Norwegian and Danish hospitals and investigate possible changes in Norway since 2001. A one-page questionnaire was sent ...

    • Co-morbidity and drug treatment in Alzheimer’s disease. A cross sectional study of participants in the Dementia Study in Northern Norway 

      Andersen, Fred; Viitanen, Matti; Halvorsen, Dag; Straume, Bjørn; Engstad, Torgeir (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Inappropriate medical treatment of co-morbidities in Alzheimer’s disease (AD) is an increasing concern in geriatric medicine. The objective of this study was to compare current drug use related to co-morbidity between individuals with a recent diagnosis of AD and a cognitively healthy control group in a population based clinical trial in Northern Norway. Setting: Nine rural municipalities with ...

    • Complementary and alternative medicine for patients with chronic fatigue syndrome : a systematic review 

      Alræk, Terje; Lee, Myeong S.; Choi, Tae-Young; Cao, Huijuan; Liu, Jianping (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Throughout the world, patients with chronic diseases/illnesses use complementary and alternative medicines (CAM). The use of CAM is also substantial among patients with diseases/illnesses of unknown aetiology. Chronic fatigue syndrome (CFS), also termed myalgic encephalomyelitis (ME), is no exception. Hence, a systematic review of randomised controlled trials of CAM treatments in patients with CFS/ME ...

    • "I did not intend to stop. I just could not stand cigarettes any more." A qualitative interview study of smoking cessation among the elderly 

      Medbø, Astri; Melbye, Hasse; Rudebeck, Carl Edvard (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Every year, more than 650,000 Europeans die because they smoke. Smoking is considered to be the single most preventable factor influencing health. General practitioners (GP) are encouraged to advise on smoking cessation at all suitable consultations. Unsolicited advice from GPs results in one of 40-60 smokers stopping smoking. Smoking cessation advice has traditionally been given on an individual ...

    • Small lytic peptides escape the inhibitory effect of heparan sulfate on the surface of cancer cells 

      Fadnes, Bodil Irene; Uhlin-Hansen, Lars; Lindin, Inger; Rekdal, Øystein (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Several naturally occurring cationic antimicrobial peptides (CAPs), including bovine lactoferricin (LfcinB), display promising anticancer activities. These peptides are unaffected by multidrug resistance mechanisms and have been shown to induce a protective immune response against solid tumors, thus making them interesting candidates for developing novel lead structures for anticancer treatment. ...

    • Hip fractures in a city in Northern Norway over 15 years : time trends, seasonal variation and mortality The Harstad Injury Prevention Study 

      Emaus, Nina; Olsen, Lena Ringstad; Ahmed, Luai A.; Balteskard, Lise; Jacobsen, Bjarne Koster; Magnus, Trine; Ytterstad, Børge (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Introduction The aim of the present population-based study was to describe age- and sex-specific incidence of hip fractures in a Northern Norwegian city, compare rates with the Norwegian capital Oslo, describe time trends in hip fracture incidence, place of injury, seasonal variation and compare mortality after hip fracture between women and men. Methods Data on hip fractures from 1994 to 2008 ...

    • Congenital anomalies in newborns to women employed in jobs with frequent exposure to organic solvents : a register-based prospective study 

      Vaktskjold, arild; Talykova, Ljudmila V; Nieboer, Evert (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      597 women employed as painters, painter-plasterers or spoolers had 712 singleton births, whereof 31 (4.4%) were perinatally diagnosed with 37 malformations. Among the 10 561 newborns in the group classified as non-exposed, 397 (3.9%) had one or more malformations. The overall prevalence in the exposed group was 520/10 000 births [95% confidence limits (CL): 476, 564], and 436/10 000 births (95% CL: ...

    • Proteases in plasma and kidney of db /db mice as markers of diabetes-induced nephropathy 

      Hadler-Olsen, Elin Synnøve; Winberg, Jan-Olof; Reinholt, Finn P.; Larsen, Terje; Uhlin-Hansen, Lars; Jenssen, Trond Geir; Berg, Eli; Kolset, Svein Olav (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Db/db mice are overweight, dyslipidemic and develop diabetic complications, relevant for similar complications in human type 2 diabetes. We have used db/db and db/+ control mice to investigate alterations in proteinase expression and activity in circulation and kidneys by SDS-PAGE zymography, electron microscopy, immunohistochemistry, Western blotting, and in situ zymography. Plasma from db/db mice ...

    • Parity and total, ischemic heart disease and stroke mortality. The Adventist Health Study, 1976-1988 

      Jacobsen, Bjarne Koster; Knutsen, Synnøve Fønnebø; Oda, Keiji; Fraser, Gary E. (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      In a prospective study with information about life style and reproductive factors, we assessed the relationship between parity and total, ischemic heart disease, and stroke mortality. The large majority of the 19,688 California Seventh-day Adventist women included did not smoke or drink alcohol, 31 percent never ate meat and physical activity was relatively high. Cox proportional hazard analysis ...

    • Tigecycline attenuates polymorphonuclear leukocyte (PMN) receptors but not functions 

      Næss, Are; Andreeva, Hristina D; Sørnes, Steinar (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Tigecycline achieves high intracellular concentrations in polymorphonuclear leukocytes (PMNs). To evaluate the effects of tigecycline on human PMNs, PMNs were incubated with tigecycline dilutions (0.1 to 100 mg L–1). Phagocytosis- associated PMN Fcg- and complement receptors as well as phagocytosis and oxidative burst induced by Staphylococcus aureus were measured by flow cytometry. Incubation ...

    • Purified sardine and king crab trypsin display individual differences in PAR-2-, NF-kB-, and IL-8 signaling 

      Larsen, Anett Kristin; Seternes, ole morten; Bang, Berit (Journal article; Tidsskriftartikkel; Peer reviewed, 2011-08-31)
      Respiratory symptoms occur in workers processing a great variety of seafood. Studies previously showed that salmon trypsin increases transcriptional activity of NF-κB and induces secretion of IL-8 from airway epithelial cells by activating PAR-2. The aim of this study was to explore if purified trypsins from king crab (Paralithodes camtschaticus) and sardine (Sardinops melanostictus) are able to ...

    • Risk of malnutrition is associated with mental health symptoms in community living elderly men and women: The Tromsø Study 

      Kvamme, Jan-Magnus; Grønli, Ole Kristian; Florholmen, Jon; Jacobsen, Bjarne Koster (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Little research has been done on the relationship between malnutrition and mental health in community living elderly individuals. In the present study, we aimed to assess the associations between mental health (particularly anxiety and depression) and both the risk of malnutrition and body mass index (BMI, kg/m2) in a large sample of elderly men and women from Tromsø, Norway. In a cross-sectional ...

    • Prevalence of self-reported suicidal thoughts in SLiCA. The Survey of Living Conditions in the Arctic ( SLiCA) 

      Broderstad, Ann Ragnhild; Eliassen, Bent-Martin; Melhus, Marita (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      The Survey of Living Condition in the Arctic (SLiCA) is an international research project on health and living conditions among Arctic indigenous peoples. The main objective of this article is to examine the prevalence of self-reported suicide thoughts among the study population in Alaska, Greenland, Sweden and Norway. This is a population-based survey. Indigenous participants aged 16 years (15 ...

    • Does long-term care use within primary health care reduce hospital use among older people in Norway? A national five-year population-based observational study 

      Deraas, Trygve Sigvart; Berntsen, Gro; Hasvold, Toralf; Førde, Olav Helge (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Population ageing may threaten the sustainability of future health care systems. Strengthening primary health care, including long-term care, is one of several measures being taken to handle future health care needs and budgets. There is limited and inconsistent evidence on the effect of long-term care on hospital use. We explored the relationship between the total use of long-term care within public ...

    • Premature cardiovascular mortality and alcohol consumption before death in Arkhangelsk, Russia : an analysis of a consecutive series of forensic autopsies 

      Sidorenkov, Oleg; Nilssen, Odd-Ragnar; Nieboer, Evert; Grjibovski, Andrej (Journal article; Tidsskriftartikkel, 2011)
      High CVD mortality among the middle-aged is a major cause of low life expectancy in Russia, especially among men. Hazardous alcohol consumption is suspected to be a powerful factor. All men (1099) and women (519) who died between 01.01.08 and 31.08.09 from cardiovascular disease at ages of 30-70 years in the city of Arkhangelsk, Northwest Russia, were included. CVD mortality was stratified by age, ...

    • Determinants of cardiovascular and all-cause mortality in northwest Russia : a 10-year follow-up study 

      Sidorenkov, Oleg; Nilssen, Odd-Ragnar (Journal article; Tidsskriftartikkel, 2012)
      Abstract PURPOSE: To study conventional and novel risk factors associated with high cardiovascular disease (CVD) and all-cause mortality in Russia. METHODS: A prospective cohort study of 3704 adults was performed in Arkhangelsk. The baseline examination was conducted in 1999-2000. The average follow-up was 10.2 years. Information on lifestyle and marital, educational, and psychosocial status was ...

    • Blood pressure, cardiorespiratory fitness and body mass : results from the Tromsø activity study 

      Wilsgaard, Tom; Furberg, Anne-Sofie (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)

    • Sex hormones and gene expression signatures in peripheral blood from postmenopausal women - the NOWAC postgenome study 

      Waaseth, Marit; Olsen, Karina Standahl; Rylander, Charlotta; Lund, Eiliv; Dumeaux, Vanessa (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)

    • In HPA 1a-immunized women the decrease in anti-HPA 1a antibody level during pregnancy is not associated with anti-idiotypic antibodies 

      Kjeldsen-Kragh, J; Killie, Mette Kjær; Kim, Michael; Husebekk, Anne; Freedman, J; Semple, John W (Journal article; Tidsskriftartikkel, 2009)

    • Biosynthesis of Promatrix Metalloproteinase-9/Chondroitin Sulphate Proteoglycan Heteromer Involves a Rottlerin-Sensitive Pathway 

      Malla, Nabin; Berg, Eli; Moens, Ugo; Uhlin-Hansen, Lars; Winberg, Jan-Olof (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Background: Previously we have shown that a fraction of the matrix metalloproteinase-9 (MMP-9) synthesized by the macrophage cell line THP-1 was bound to a chondroitin sulphate proteoglycan (CSPG) core protein as a reduction sensitive heteromer. Several biochemical properties of the enzyme were changed when it was bound to the CSPG. <br>Methodology/Principal Findings: By use of affinity chromatography, ...