Now showing items 821-840 of 1800

    • Incidence of gynecological fistula and its surgical treatment: A national registry-based study 

      Børseth, Katrine Trovik Flaatten; Acharya, Ganesh; Kiserud, Torvid; Trovik, Jone (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-03-19)
      <i>Introduction</i> - Gynecological fistula (affecting female genital organs) leads to involuntary loss of urine or feces. In industrialized societies, fistulas occur mostly as complications of surgery, radiation therapy or inflammatory bowel disease. We sought to determine the incidence of gynecological fistula and type of surgical treatment provided in Norway.<p><p> <i>Material and methods</i> ...
    • Continuing increased risk of second cancer in long-term testicular cancer survivors after treatment in the cisplatin era 

      Hellesnes, Ragnhild; Kvammen, Øivind; Myklebust, Tor Åge; Bremnes, Roy M.; Karlsdottir, Åsa; Negaard, Helene Francisca Stigter; Tandstad, Torgrim; Wilsgaard, Tom; Fosså, Sophie Dorothea; Haugnes, Hege Sagstuen (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-09)
      Using complete information on total treatment burden, this population‐based study aimed to investigate second cancer (SC) risk in testicular cancer survivors (TCS) treated in the cisplatin era. The Cancer Registry of Norway identified 5,625 1‐year TCS diagnosed 1980–2009. Standardized incidence ratios (SIRs) were calculated to evaluate the total and site‐specific incidence of SC compared to the ...
    • Isoflurane increases tolerance to renal ischemia reperfusion injury compared to propofol: An experimental study in pigs 

      Roaldsen, Marius Håke; Ciosek, Timothy Allan; Richardsen, Elin; Al-Saad, Samer; Patel, Hitendra R.H.; Aarsæther, Erling Johan (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-09)
      <i>Purpose</i>: To compare two clinically relevant anesthetic agents, i.e., isoflurane versus propofol with respect to protection of the kidney in a porcine renal ischemia reperfusion model. <p> <p><i>Materials and Methods</i>: 14 hybrid pigs were randomized to anesthesia with either isoflurane or propofol prior to laparoscopic surgery. Following anesthesia, the left kidney hilum was clamped for ...
    • Sex-specific reference ranges of cerebroplacental and umbilicocerebral ratios: A longitudinal study 

      Acharya, Ganesh; Ebbing, Cathrine; Karlsen, Henriette Odland; Kiserud, Torvid; Rasmussen, Svein (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-10)
      <p><i>Objectives - </i>The ratio of middle cerebral artery (MCA) pulsatility index (PI) to umbilical artery (UA) PI, i.e. cerebro‐placental ratio (CPR), has been suggested as a measure of fetal “brain sparing” phenomenon reflecting redistribution of fetal cardiac output as a response to placental insufficiency. Observational studies have shown that low CPR values predict increased risk of adverse ...
    • Myocardial infarction as a transient risk factor for incident venous thromboembolism: Results from a population-based case-crossover study 

      Sejrup, Joakim Knutsen; Børvik, Trond; Grimnes, Gro; Isaksen, Trond; Hindberg, Kristian; Hansen, John-Bjarne; Morelli, Vania Maris; Brækkan, Sigrid Kufaas (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-06-16)
      Patients with myocardial infarction (MI) are at increased short-term risk of venous thromboembolism (VTE). The mechanisms behind this association are unclear. We aimed to investigate the impact of acute MI as a transient risk factor for incident VTE while taking other concomitant VTE risk factors into account. We conducted a case–crossover study of VTE patients (<i>n</i> = 707) recruited from the ...
    • Amnioexchange for gastroschisis does not help, and may even harm 

      Bhide, Amarnath (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-05-24)
      This is a mini commentary on D Luton et al., pp. 1233–1241 in this issue. To view this article visit https://doi.org/10.1111/1471-0528.15804.
    • Initiation of systemic therapy during the last 30 days of life in patients with metastatic castration-resistant prostate cancer 

      Nieder, Carsten; Haukland, Ellinor Christin; Mannsåker, Bård; Pawinski, Adam; Yobuta, Rosalba; Norum, Jan (Journal article; Tidsskriftartikkel; Peer reviewed, 2019)
      <b>Background/Aim</b>: Compared to intravenous taxane chemotherapy, newer orally-available and/or less toxic agents for metastatic castration-resistant prostate cancer (MCRPC) may be associated with higher likelihood of starting treatment in patients with adverse prognostic features and limited life expectancy. To test this hypothesis, we analyzed the rates of treatment initiation during the last ...
    • Fetal and neonatal alloimmune thrombocytopenia - The Norwegian management model 

      Tiller, Heidi; Ahlen, Maria Therese; Akkøk, Cigdem Ahaein; Husebekk, Anne (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-31)
      In Norway, the management strategy for fetal and neonatal alloimmune thrombocytopenia (FNAIT) has for more than two decades differed from most other countries. The focus of this paper is to describe and discuss the Norwegian FNAIT management program. We recommend antenatal IVIg to women who previously have had a child with FNAIT-induced ICH, and usually not to HPA-1a alloimmunized pregnant women ...
    • Measuring the effects of sharing mHealth data during diabetes consultations: a mixed-method study protocol 

      Bradway, Meghan; Giordanengo, Alain; Joakimsen, Ragnar Martin; Hansen, Anne Helen; Grøttland, Astrid; Hartvigsen, Gunnar; Randine, Pietro; Årsand, Eirik (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-02-10)
      <i>Background</i>: There is rising demand for health care’s limited resources. Mobile health (mHealth) could be a solution, especially for those with chronic illnesses such as diabetes. mHealth can increases patients’ options to self-manage their health, improving their health knowledge, engagement, and capacity to contribute to their own care decisions. However, there are few solutions for sharing ...
    • Psychiatric Risk Assessment from the Clinician´s Perspective: Lessons for the Future 

      Cohen, Alex S.; Fedechko, Taylor L.; Schwartz, Elana K.; Le, Thanh P.; Foltz, Peter W.; Bernstein, Jared; Cheng, Jian; Rosenfeld, Elizabeth; Elvevåg, Brita (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-06-01)
      Accurate prediction of risk-states in Serious Mental Illnesses (SMIs) is critical for reducing their massive societal burden. Risk-state assessments are notably inaccurate. Recent innovations, including widely available and inexpensive mobile technologies for ambulatory “biobehavioral” data, can reshape risk assessment. To help understand and accelerate clinician involvement, we surveyed 90 ...
    • Second re-irradiation: A delicate balance between safety and efficacy 

      Nieder, Carsten (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-08)
      Except for straightforward palliative indications such as painful bone metastases, re-irradiation is often characterized by a narrow therapeutic window and the potential for decreased efficacy and increased toxicity, especially if the cumulative total dose from both courses is high. Second re-irradiations tend to pose even bigger challenges and are thus offered in a restrictive manner to highly ...
    • Simuleringsbasert teamtrening virker 

      Brattebø, Guttorm; Ersdal, Hege Langli; Wisborg, Torben (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-09)
      Trening av tverrprofesjonelle team med bruk av simulering brukes særlig ved forberedelse til akuttmedisinske situasjoner. Det foreligger nå god dokumentasjon for at slik trening har betydning for pasientene. 27. mars 1977 skjedde verdens hittil verste flykatastrofe, der 583 personer omkom på Tenerife etter at to jumbojeter kolliderte på flyplassen i tett tåke. Granskningen etter katastrofen ...
    • Hospitalization as a trigger for venous thromboembolism – Results from a population-based case-crossover study 

      Bjøri, Esben; Johnsen, Håkon Sandbukt; Hansen, John-Bjarne; Brækkan, Sigrid Kufaas (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-02-21)
      <i>Background</i> - Previous studies have reported that around 50% of patients with venous thromboembolism (VTE) has undergone recent hospitalization. However, studies on the impact of hospitalization as a trigger factor for VTE are limited.<p><p> <i>Objectives</i> - To investigate the impact of hospitalization with and without concurrent immobilization as a trigger factor for VTE.<p><p> ...
    • Agreement between anatomical M-mode and tissue Doppler imaging in the assessment of fetal atrioventricular annular plane displacement in uncomplicated pregnancies: A prospective longitudinal study 

      Zanardini, Cristina; D'Antonio, Francesco; Hvingel, Bodil; Vårtun, Åse; Prefumo, Federico; Flacco, Maria E.; Manzoli, Lamberto; Acharya, Ganesh (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-08-23)
      Aim To evaluate the level of agreement between M‐mode and pulsed‐wave tissue Doppler imaging (PW‐TDI) techniques in assessing fetal mitral annular plane systolic excursion (MAPSE), tricuspid annular plane systolic excursion (TAPSE) and septal annular plane systolic excursion (SAPSE) in a low‐risk population. Methods This prospective longitudinal study included healthy fetuses assessed from 18 to ...
    • Genetic Variation Of Platelet Glycoprotein VI And The Risk Of Venous Thromboembolism 

      Skille, Hanne; Paulsen, Benedikte; Hveem, Kristian; Gabrielsen, Maiken Elvestad; Brumpton, Ben Michael; Hindberg, Kristian; Gran, Olga Vikhammer; Rosendaal, Frits Richard; Brækkan, Sigrid Kufaas; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-11-07)
      Family studies have indicated that heritability explains 50-60% of the venous thromboembolism (VTE) events, and in recent years, several single nucleotide polymorphisms (SNPs) have been found to influence the VTE risk. Glycoprotein 6 (GP6) rs1613662, also known as T13254C, is an A/G single nucleotide variation in amino acid 219, which results in a serine to proline substitution affecting ...
    • Chronic obstructive pulmonary Disease and risk of mortality in patients with venous thromboembolism - the Tromsø Study 

      Børvik, Trond; Brækkan, Sigrid Kufaas; Evensen, Line; Brodin, Ellen Elisabeth; Morelli, Vania Maris; Melbye, Hasse; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-30)
      <i>Background</i> - Previous studies have shown increased mortality in venous thromboembolism (VTE) patients with chronic obstructive pulmonary disease (COPD), but it is unknown to what extent the association is influenced by the severity of COPD and physical inactivity.<p> <p><i>Objectives</i> - This article investigates whether COPD, and stages of COPD, influenced the risk of mortality after a ...
    • Standardizing Terminology and Assessment for Orofacial Conditions in Juvenile Idiopathic Arthritis: International, Multidisciplinary Consensus-based Recommendations 

      Stoustrup, Peter; Resnick, Cory M; Pedersen, Thomas Klit; Abramowicz, Shelly; Michelotti, Ambra; Küseler, Annelise; Verna, Carlalberta; Kellenberger, Christian J.; Nordal, Ellen Berit; Caserta, Giuliana; Jankovska, Iveta; Halbig, Josefine Mareile; Kristensen, Kasper Dahl; Arvidsson, Linda Zamoline; Spiegel, Lynn; Stoll, Mathew L.; Lerman, Melissa; Glerup, Mia; Defabianis, Patrizia; Frid, Paula Hanna Therese; Alstergren, Per; Cron, Randy Q.; Ringold, Sarah; Nørholt, Sven Erik; Peltomäki, Timo; Herlin, Troels; Peacock, Zachary S.; Twilt, Marinka (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-05-01)
      <i>Objective</i> - To propose multidisciplinary, consensus-based, standardization of operational terminology and method of assessment for temporomandibular joint (TMJ) involvement in juvenile idiopathic arthritis (JIA).<p> <p><i>Methods</i> - Using a sequential expert group–defined terminology and methods-of-assessment approach by (1) establishment of task force, (2) item generation, (3) working ...
    • Prevalens av diabetes blant gravide og svangerskapsutfall i Nordland og Troms 2004-15 

      Leeves, Lisa Tangnes; Andreasen, Camilla; Olsen, Ingrid Petrikke; Bjørnerem, Åshild; Marrable, Sire; Glasø, Martine Utland; Rostad, Mia-Kristin (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-09)
      <i>BAKGRUNN</i> - Formålet var å undersøke prevalens av diabetes i svangerskapet og svangerskapsutfall hos kvinner med diabetes i svangerskapet i Nordland og Troms.<p> <p><i>MATERIALE OG METODE</i> - Vi inkluderte alle 1 067 kvinner med type 1-diabetes, type 2-diabetes og svangerskapsdiabetes blant 34 915 fødsler ved fire sykehus i Nordland og Troms fra 2004 til 2015. Prevalens av diabetes ble ...
    • Association of Achieving Lupus Low Disease Activity State Fifty Percent of the Time With Both Reduced Damage Accrual and Mortality in Patients With Systemic Lupus Erythematosus 

      Sharma, Chanakya; Raymond, Warren David; Eilertsen, Gro Østli; Nossent, Johannes (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-03-01)
      <i>Objective</i> - To assess the impact of achieving Lupus Low Disease Activity State ≥50% of the time (LLDAS‐50) on damage accrual and mortality in an inception cohort of patients with systemic lupus erythematosus (SLE).<p><p> <i>Methods</i> - We used data from the Tromsø Lupus Cohort, a longitudinal population‐based study of all patients with SLE in the 2 northernmost counties in Norway. ...
    • Data work in healthcare: An Introduction 

      Bossen, Claus; Pine, Katie; Cabitza, Federico; Ellingsen, Gunnar; Piras, Enrico Maria (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-08-12)
      Why data work in healthcare?<p> <p>Healthcare organizations across the globe are currently grappling to implement tools and practices to transform data from “refuse to riches,” a movement propelled by mass adoption of electronic health records (EHRs), sensors, and servers that can hold an ever-expanding volume of digital data. Allegedly, “By digitizing, combining and effectively using big data, ...