Institutt for klinisk medisin: Nye registreringer

Viser treff 1381-1400 av 1801

    • Social representation of hearing aids: Cross-cultural study in India, Iran, Portugal, and the United Kingdom 

      Manchaiah, Vinaya; Danermark, Berth; Vinay, Sandhya; Ahmadi, Tayebeh; Tome, David; Krishnan, R.; Germundsson, Per (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-10-06)
      Background: The current study was aimed at understanding the social representation of hearing aids in India, Iran, Portugal, and the United Kingdom. We also compared these results to explore the cross-cultural differences and similarities among these countries. <p>Methods: The study involved a cross-sectional design, and the data were collected from four different countries using the snowball ...

    • Prediabetes and Risk of Glomerular Hyperfiltration and Albuminuria in the General Nondiabetic Population: A Prospective Cohort Study 

      Melsom, Toralf; Schei, Jørgen; Stefansson, Vidar Tor Nyborg; Solbu, Marit Dahl; Jenssen, Trond Geir; Mathisen, Ulla Dorte; Wilsgaard, Tom; Eriksen, Bjørn Odvar (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-12-29)

    • Comprehensive pulmonary rehabilitation in home-based online groups: A mixed method pilot study in COPD 

      Burkow, Tatjana M.; Vognild, Lars Kristian; Johnsen, Elin; Risberg, Marijke Jongsma; Bratvold, Astrid; Breivik, Elin; Krogstad, Trine; Hjalmarsen, Audhild (Journal article; Tidsskriftartikkel, 2015-12-10)
      Background: Comprehensive multidisciplinary pulmonary rehabilitation is vital in the management of chronic obstructive pulmonary disease (COPD) and is considered for any stage of the disease. Rehabilitation programmes are often centre-based and organised in groups. However, the distance from the patient’s home to the centre and lack of transportation may hinder participation. Rehabilitation at ...

    • Low oxygen saturation and mortality in an adult cohort; the Tromsø Study 

      Vold, Monica Linea; Aasebø, Ulf; Wilsgaard, Tom; Melbye, Hasse (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-02-12)
      Background: Oxygen saturation has been shown in risk score models to predict mortality in emergency medicine. The aim of this study was to determine whether low oxygen saturation measured by a single-point measurement by pulse oximetry (SpO2) is associated with increased mortality in the general adult population. <p>Methods: Pulse oximetry was performed in 5,152 participants in a cross-sectional ...

    • Prevalence and characteristics of suicide attempters and ideators among acutely admitted psychiatric patients in northwest Russia and northern Norway 

      Sørlie, Tore; Sørgaard, Knut W.; Bogdanov, Anatoly; Bratlid, Trond; Rezvy, Grigory (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-08-04)
      Background: More knowledge about suicidality and suicide risk profiles in acute psychiatric hospital patients (both first-time and chronic patients) is needed. While numerous factors are associated with suicidality in such populations, these may differ across cultures. Better understanding of factors underlying suicide risk can be informed by cross-cultural studies, and can aid development of ...

    • Staphylococcus Aureus carriage and long-term Rituximab treatment for Granulomatosis with polyangiitis 

      Besada, Emilio; Koldingsnes, Wenche; Nossent, Hans C (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-06-25)
      Objective. Chronic nasal carriage of Staphylococcus aureus (SA) increases the risk of relapse while Rituximab (RTX) is an effective agent for inducing and maintaining remission in patients with Granulomatosis with polyangiitis (GPA). We investigated whether B cell depletion and hypogammaglobulinemia that occur during RTX treatment increase the risk of chronic SA nasal carriage and subsequent ...

    • Serglycin is part of the secretory repertoire of LPS-activated monocytes 

      Kolseth, Ingrid Moss; Reine, Trine M.; Vuong, Tram Thu; Meen, Astri Jeanette; Fan, Qiong; Jenssen, Trond Geir; Grønning-Wang, Line Mariann; Kolset, Svein Olav (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-02-11)
      Monocytes play multiple roles in the immune system, and are active in both acute and chronic diseases. Patients exposed to bacterial infections depend on monocytes in defense reactions, but excessive immune reactions may also cause morbidity through systemic inflammatory responses. Few studies have addressed the importance of proteoglycans, and in particular, the hematopoietic serglycin, in such ...

    • Does concomitant methotrexate during rituximab treatment in granulomatosis with polyangiitis (Wegener's) increase the risk of severe infection? Comment on the article by Azar et al 

      Besada, Emilio; Diamantopoulos, Andreas P (Journal article; Tidsskriftartikkel, 2015-06-26)

    • Randomized trial of a novel game-based appointment system for a university hospital venereology unit: Study protocol 

      Gabarron, Elia; Fernandez-Luque, Luis; Serrano, Artur; Wynn, Rolf; Schopf, Thomas Roger Griesbeck (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-04-08)
      Background: Chlamydia is the most common reportable sexually transmitted disease (STD) in Norway, and its incidence in the two northernmost counties has been disclosed to be nearly the double of the Norwegian average. The latest publicly available rates showed that 85.6% of the new cases were diagnosed in people under 29 years old. The information and communication technologies are among the most ...

    • Impact of red cell distribution width on future risk of cancer and all-cause mortality among cancer patients – the Tromsø Study 

      Ellingsen, Trygve; Lappegård, Jostein; Skjelbakken, Tove; Brækkan, Sigrid Kufaas; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-10)

    • Quantitative home-based assessment of Parkinson’s symptoms: The SENSE-PARK feasibility and usability study 

      Ferreira, Joaquim J; Godinho, Catarina; Santos, Ana T.; Domingos, Josefa; Abreu, Daisy; Lobo, Raquel; Larsen, Frank Atle; Fagerbakke, Øyvind; Akeren, Ingvild; Wangen, Hilde; Serrano, Artur; Weber, Peter; Thoms, Andrea; Meckler, Stefan; Sollinger, Stefan; Uem, Janet van; Hobert, Markus A; Maier, Karin S; Matthew, Helen; Isaacs, Tom; Duffen, Joy; Graessner, Holm; Maetzler, Walter (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-06-10)
      Background: Currently, assessment of symptoms associated with Parkinson’s disease is mainly performed in the clinic. However, these assessments have limitations because they provide only a snapshot of the condition. <p>Methods: The feasibility and usability of an objective, continuous and relatively unobtrusive system (SENSE-PARK System), which consists of wearable sensors (three worn during the ...

    • Uric acid is associated with microalbuminuria and decreased glomerular filtration rate in the general population during 7 and 13 years of follow-up: The Tromsø Study 

      Storhaug, Hilde-Merete; Toft, Ingrid; Norvik, Jon Viljar; Jenssen, Trond Geir; Eriksen, Bjørn Odvar; Melsom, Toralf; Løchen, Maja-Lisa; Solbu, Marit Dahl (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-12-11)
      Background: The role of uric acid in development of renal dysfunction (RD) remains controversial. Earlier studies have reported inconsistent results, possibly because of their varying ability to adjust for confounding. The impact of longitudinal change in uric acid on renal outcome has not been assessed previously. We aimed to study the impact of change in serum uric acid (SUA) as well as baseline ...

    • Mortality and one-year functional outcome in elderly and very old patients with severe traumatic brain injuries: observed and predicted 

      Røe, Cecilie; Skandsen, Toril; Manskow, Unn Sollid; Ader, Tiina; Anke, Audny (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-11)
      The aim of the present study was to evaluate mortality and functional outcome in old and very old patients with severe traumatic brain injury (TBI) and compare to the predicted outcome according to the internet based CRASH (Corticosteroid Randomization After Significant Head injury) model based prediction, from the Medical Research Council (MRC). Methods. Prospective, national multicenter study ...

    • Inflammatory response after laparoscopic versus open resection of colorectal liver metastases: Data from the oslo-comet trial 

      Fretland, Åsmund Avdem; Sokolov, Andrey; Postriganova, Nadezda; Kazaryan, Airazat M.; Pischke, Søren Erik; Nilsson, Per; Rognes, Ingrid Nygren; Bjørnbeth, Bjørn Atle; Fagerland, Morten; Mollnes, Tom Eirik; Edwin, Bjørn (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-10)
      Laparoscopic and open liver resection have not been compared in randomized trials. The aim of the current study was to compare the inflammatory response after laparoscopic and open resection of colorectal liver metastases (CLM) in a randomized controlled trial. This was a predefined exploratory substudy within the Oslo CoMetstudy. Forty-five patients with CLM were randomized to laparoscopic (n ...

    • Early intervention influences positively quality of life as reported by prematurely born children at age nine and their parents; a randomized clinical trial 

      Landsem, Inger Pauline; Handegård, Bjørn Helge; Ulvund, Stein Erik; Kaaresen, Per Ivar; Rønning, John Andreas (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-02-22)
      Background: The Tromsø Intervention Study on Preterms evaluates an early, sensitizing intervention given to parents of prematurely born children (birth-weight < 2000 g). The current study investigated the potential influence of the intervention on children’s self-reported and parental proxy-reported quality of life (QoL) at children’s age of nine. <p>Methods: Participants were randomized to either ...

    • Is there a weekly pattern for health information searching and is the pattern unique to health topics? 

      Gabarron, Elia; Lau, Annie YS; Wynn, Rolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-12)
      Background: Online health information–seeking behaviors have been reported to be more common at the beginning of the workweek. This behavior pattern has been interpreted as a kind of “healthy new start” or “fresh start” due to regrets or attempts to compensate for unhealthy behavior or poor choices made during the weekend. However, the observations regarding the most common health information–seeking ...

    • Ketamine for prehospital trauma analgesia in a low-resource rural trauma system: a retrospective comparative study of ketamine and opioid analgesia in a ten-year cohort in Iraq 

      Losvik, Ole Kristian; Murad, Mudhafar Kareem; Skjerve, Eystein; Husum, Hans (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-11-09)
      Background Opioid analgesics are used in most trauma systems, and only a few studies report on the use of ketamine for prehospital analgesia. In a low-cost rural trauma system in Iraq paramedics have been using prehospital ketamine analgesia for ten years. This study aims to evaluate the effects of prehospital analgesia on physiologic trauma severity indicators and compare the effect of ketamine ...

    • Relationship between the quality of service provided through store-and-forward telemedicine consultations and the difficulty of the cases – implications for long-term quality assurance 

      Wootton, Richard; Liu, Joanne; Bonnardot, Laurent (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-09-25)
      We examined the difficulty of telemedicine cases and the quality of the resultant consultation in a mature store-and-forward telemedicine network. A random sample of 10 telemedicine cases was selected from those occurring over a 3-month period (5% of the workload) and they were scored by three experienced observers. Inter-observer agreement on the difficulty scores was poor (Fleiss’s kappa = 0.18) ...

    • Experience with quality assurance in two store-and-forward telemedicine networks 

      Wootton, Richard; Liu, Joanne; Bonnardot, Laurent; Venugopal, Raghu; Oakley, Amanda (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-11-26)
      Despite the increasing use of telemedicine around the world, little has been done to incorporate quality assurance (QA) into these operations. The purpose of the present study was to examine the feasibility of QA in store-and-forward teleconsulting using a previously published framework. During a 2-year study period, we examined the feasibility of using QA tools in two mature telemedicine networks ...

    • Cancer-associated fibroblasts from lung tumors maintain their immunosuppressive abilities after high-dose irradiation 

      Gorchs, Laia; Hellevik, Turid; Bruun, Jack-Ansgar; Camilio, Ketil Andre; Al-Saad, Samer; Stuge, Tor Brynjar; Martinez, Inigo Zubiavrre (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-05-12)
      Accumulating evidence supports the notion that high-dose (>5 Gy) radiotherapy (RT) regimens are triggering stronger pro-immunogenic effects than standard low-dose (2 Gy) regimens. However, the effects of RT on certain immunoregulatory elements in tumors remain unexplored. In this study, we have investigated the effects of high-dose radiotherapy (HD-RT) on the immunomodulating functions of cancer-associated ...