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dc.contributor.authorLundanes, Julianne
dc.contributor.authorSandnes, Frida Huhta
dc.contributor.authorGjeilo, Kari Hanne
dc.contributor.authorSalater, Sissel
dc.contributor.authorAlho Letra Martins, Catia Patricia
dc.contributor.authorNymo, Siren
dc.contributor.authorHanson, Patrik
dc.date.accessioned2024-10-04T09:04:35Z
dc.date.available2024-10-04T09:04:35Z
dc.date.issued2024-04-16
dc.description.abstractObjective: The primary objective of this study was to evaluate the effect of a low-carbohydrate diet (LCD) compared with a control diet on pain in female patients with lipedema. The secondary objectives were to compare the impact of the two diets on quality of life (QoL) and investigate potential associations of changes in pain with changes in body weight, body composition, and ketosis.<p> <p>Methods: Adult female patients with lipedema and obesity were randomized to either the LCD or control diet (energy prescription: 1200 kcal/day) for 8 weeks. Body weight and body composition, pain (Brief Pain Inventory measured pain), and QoL (RAND 36-Item Health Survey [RAND-36], Impact of Weight on Quality of Life [IWQOL]-Lite, and Lymphoedema Quality of Life [LYMQOL]) were measured at baseline and at postintervention. <p>Results: A total of 70 female patients (age, mean [SD], 47 [11] years; BMI 37 [5] kg/m<sup>2</sup> ) were included. The LCD group had greater weight loss ( 2.8 kg; 95% CI: 4.1 to 1.0; p < 0.001) and larger reduction in pain now ( 1.1; 95% CI: 1.9 to 0.3; p = 0.009) compared with the control group. No association was found between changes in pain now and weight loss. Both groups experienced improvements in several QoL dimensions. <p>Conclusions: Diet-induced weight loss in women with lipedema can improve QoL. An energy-restricted LCD seems to be superior to a standard control diet in reducing pain.en_US
dc.identifier.citationLundanes, Sandnes, Gjeilo, Hansson, Salater, Alho Letra Martins, Nymo. Effect of a low-carbohydrate diet on pain and quality of life in female patients with lipedema: a randomized controlled trial. Obesity. 2024en_US
dc.identifier.cristinIDFRIDAID 2267929
dc.identifier.doi10.1002/oby.24026
dc.identifier.issn1930-7381
dc.identifier.issn1930-739X
dc.identifier.urihttps://hdl.handle.net/10037/35045
dc.language.isoengen_US
dc.publisherWileyen_US
dc.relation.journalObesity
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2024 The Author(s)en_US
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0en_US
dc.rightsAttribution-NonCommercial 4.0 International (CC BY-NC 4.0)en_US
dc.titleEffect of a low-carbohydrate diet on pain and quality of life in female patients with lipedema: a randomized controlled trialen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
Except where otherwise noted, this item's license is described as Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)