Now showing items 1841-1860 of 10407

    • Autoregulation of Cerebral Blood Flow During 3-h Continuous Cardiopulmonary Resuscitation at 27°C 

      Valkov, Sergei; Nilsen, Jan Harald; Mohyuddin, Rizwan; Schanche, Torstein Lindahl; Kondratyev, Timofey; Sieck, Gary C.; Tveita, Torkjel (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-09)
      Introduction: Victims of accidental hypothermia in hypothermic cardiac arrest (HCA) may survive with favorable neurologic outcome if early and continuous prehospital cardiopulmonary resuscitation (CPR) is started and continued during evacuation and transport. The efficacy of cerebral autoregulation during hypothermic CPR is largely unknown and is aim of the present experiment.<p> <p>Methods: ...
    • Chinese Patent Medicine Shufeng Jiedu Capsules as an Adjuvant Therapy for Community-Acquired Pneumonia: A Systematic Review and Meta-Analysis of Randomized Clinical Trials 

      Zhang, Xiao-Wen; Xia, Ru-Yu; Gao, Jia-Qi; Liu, Jin-Jun; Xu, De-Hao; Li, Xun; Hu, Xiao-Yang; Willcox, Merlin; Moore, Michael; Dai, Meng-Yuan; Trill, Jeanne; Fei, Yu-Tong; Liu, Jianping (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-04)
      Background: Shufeng Jiedu (SFJD) capsules can be used as adjunctive treatment for patients with community-acquired pneumonia, but the effectiveness and safety of SFJD are not clear. This review aims to evaluate the effectiveness and safety of SFJD based on randomized controlled trials (RCTs).<p> <p>Methods: A systematic review was conducted by searching PubMed, Embase, Scopus, Web of Science, ...
    • The relationships between use of alcohol, tobacco and coffee in adolescence and mood disorders in adulthood 

      Bolstad, Ingeborg; Alakokkare, Anni-Emilia; Bramness, Jørgen Gustav; Rognli, Eline B.; Levola, Jonna; Mustonen, Antti; Miettunen, Jouko; Niemelä, Solja (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-22)
      Introduction: Alcohol, tobacco and coffee are commonly used substances and use in adolescence has previously been linked to mood disorders. However, few large prospective studies have investigated adolescent use in relation to mental health outcomes in adulthood. The main aim of this study was to examine the prospective associations between alcohol use, cigarette smoking and coffee consumption ...
    • Target Values and Daytime Variation of Bone Turnover Markers in Monitoring Osteoporosis Treatment After Fractures 

      Borgen, Tove Tveitan; Solberg, Lene Bergendal; Lauritzen, Trine; Apalset, Ellen Margrete; Bjørnerem, Åshild Marit; Eriksen, Erik Fink (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-22)
      The serum bone turnover markers (BTM) procollagen type 1 N-terminal propeptide (P1NP) and C-terminal cross-linking telopeptide of type 1 collagen (CTX) are recommended for monitoring adherence and response of antiresorptive drugs (ARD). BTM are elevated about 1 year after fracture and therefore BTM target values are most convenient in ARD treatment follow-up of fracture patients. In this prospective ...
    • Antenatal intravenous immunoglobulins in pregnancies at risk of fetal and neonatal alloimmune thrombocytopenia: comparison of neonatal outcome in treated and nontreated pregnancies 

      Ernstsen, Siw Leiknes; Ahlen, Maria Therese; Johansen, Tiril; Bertelsen, eirin listau; Kjeldsen-Kragh, Jens; Tiller, Heidi (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-29)
      BACKGROUND: Maternal alloantibodies to human platelet antigen-1a can cause severe intracranial hemorrhage in a fetus or newborn. Although never evaluated in placebo-controlled clinical trials, most Western countries use off-label weekly administration of high-dosage intravenous immunoglobulin in all pregnant women with an obstetrical history of fetal and neonatal alloimmune thrombocytopenia. In ...
    • Determinants of blood acylcarnitine concentrations in healthy individuals of the European Prospective Investigation into Cancer and Nutrition 

      Wedekind, Roland; Rothwell, Joseph A.; Viallon, Vivian; Keski-Rahkonen, Pekka; Schmidt, Julie A.; Chajes, Veronique; Katzke, Vna; Johnson, Theron; Santucci de Magistris, Maria; Krogh, Vittorio; Amiano, Pilar; Sacerdote, Carlotta; Redondo-Sánchez, Daniel; Huerta, José María; Tjønneland, Anne; Pokharel, Pratik; Jakszyn, Paula; Tumino, Rosario; Ardanaz, Eva; Sandanger, Torkjel M; Winkvist, Anna; Hultdin, Johan; Schulze, Matthias B.; Weiderpass, Elisabete; Gunter, Marc J.; Huybrechts, Inge; Scalbert, Augustin (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-08)
      Background & aims: Circulating levels of acylcarnitines (ACs) have been associated with the risk of various diseases such as cancer and type 2 diabetes. Diet and lifestyle factors have been shown to influence AC concentrations but a better understanding of their biological, lifestyle and metabolic determinants is needed. <p><p>Methods: Circulating ACs were measured in blood by targeted (15 ACs) and ...
    • Providing a short and effective transdiagnostic treatment intervention and a valid outcome measure for adolescent with anxiety and depression. A randomized controlled trial of the SMART intervention and validation of the CORE-OM in adolescents aged 14 to 17 

      Lorentzen, Veronica (Doctoral thesis; Doktorgradsavhandling, 2022-12-15)
      Anxiety and depression are the most prevalent mental health problems among children and adolescents, and the consequences can be harmful if they are left untreated. Providing short and effective treatment for this group is paramount. When this effectiveness study of The Structured Material for Therapy (SMART) was conducted, it was the first Randomized Controlled Trial (RCT) of short-term transdiagnostic ...
    • Norwegian Cross-Cultural Adaptation of the Social and Communities Opportunities Profile-Mini for Persons with Concurrent Mental Health and Substance Use Disorders. 

      Leonhardt, Marja; Kyrdalen, Ellen; Holstad, Atle; Solbakken, Heidi Hurlen; Chiu, Marcus YL; Lien, Lars (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-05)
      Persons with concurrent mental health and substance use disorders often do not participate actively in society and remain marginalized. The promotion of social inclusion is important for the care of persons with concurrent disorders. To measure social inclusion, the Social and Communities Opportunities Profile (SCOPE) was developed, followed by its mini version for English-speaking people in Singapore. ...
    • Interlaboratory evaluation of a digital holographic microscopy–based assay for label-free in vitro cytotoxicity testing of polymeric nanocarriers 

      Marzi, Anne; Eder, Kai Moritz; Barroso, Álvaro; Wågbø, Ane Marit; Mørch, Ýrr Asbjørg; Hatletveit, Anne Rein; Visnes, Torkild; Schmid, Ruth Baumberger; Klinkenberg, Geir; Kemper, Björn; Schnekenburger, Jürgen (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-08)
      State-of-the-art in vitro test systems for nanomaterial toxicity assessment are based on dyes and several staining steps which can be affected by nanomaterial interference. Digital holographic microscopy (DHM), an interferometry-based variant of quantitative phase imaging (QPI), facilitates reliable proliferation quantification of native cell populations and the extraction of morphological features ...
    • Measuring Engagement with Mental Health and Behavior Change Interventions: an Integrative Review of Methods and Instruments 

      Bijkerk, Laura Esther; Oenema, Anke; Geschwind, Nicole; Spigt, Marcus (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-16)
      Background - Engagement is a complex construct consisting of behavioral, cognitive, and affective dimensions, making engagement a difficult construct to measure. This integrative review aims to (1) present a multidisciplinary overview of measurement methods that are currently used to measure engagement with adult mental health and behavior change interventions, delivered in-person, blended, or ...
    • Extending the EQ-5D: the case for a complementary set of 4 psycho-social dimensions 

      Chen, Gang; Olsen, Jan Abel (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-20)
      Objectives - The EQ-5D is the most widely applied preference-based health-related quality of life measure. However, concerns have been raised that the existing dimensional structure lacks sufficient components of mental and social aspects of health. This study empirically explored the performance of a coherent set of four psycho-social bolt-ons: Vitality; Sleep; Personal relationships; and Social ...
    • Surgery for degenerative cervical myelopathy in the elderly: a nationwide registry-based observational study with patient-reported outcomes 

      Johansen, Tonje Okkenhaug; Vangen-Lønne, Vetle; Holmberg, Siril Therese; Salvesen, Øyvind; Solberg, Tore; Gulati, Agnete Malm; Nygaard, Øystein Petter; Gulati, Sasha (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-19)
      Background - The aim of this study was to investigate whether clinical outcomes in patients aged ≥ 70 undergoing decompressive surgery for degenerative cervical myelopathy (DCM) differ from those of younger patients (50–70 years) at 1 year.<p> <p>Methods - Data were obtained from the Norwegian Registry for Spine Surgery (NORspine). Among 651 patients included, 177 (27.2%) were ≥ 70 years old. The ...
    • Accuracy of neuropathic pain measurements in patients with symptoms of polyneuropathy: validation of painDETECT, Self-Completed Leeds Assessment of Neuropathic Symptoms and Signs, and Douleur Neuropathique 4 

      Dunker, Øystein; Grotle, Margreth; Kvaløy, Marie Bu; Uglem, Martin; Løseth, Sissel; Hjelland, Ina Elen; Kleggetveit, Inge Petter; Allen, Sara Maria; Vigeland, Maria Dehli; Killingmo, Rikke Munk; Sand, Trond; Nilsen, Kristian Bernhard (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-10)
      Pain is a common symptom in patients referred to polyneuropathy assessment. Diagnostic evaluation and choice of treatment may depend on whether the pain is likely to be neuropathic or not. This study aimed to investigate the diagnostic accuracy of 3 tools commonly used to differentiate between neuropathic and nonneuropathic pain. To accomplish this, we included patients with bilateral distal lower ...
    • Both brain size and biological sex contribute to variation in white matter microstructure in middle-aged healthy adults 

      Eikenes, Live; Visser, Eelke; Vangberg, Torgil Riise; Håberg, Asta (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-03)
      Whether head size and/or biological sex influence proxies of white matter (WM) microstructure such as fractional anisotropy (FA) and mean diffusivity (MD) remains controversial. Diffusion tensor imaging (DTI) indices are also associated with age, but there are large discrepancies in the spatial distribution and timeline of age-related differences reported. The aim of this study was to evaluate the ...
    • Mothers’ Domestic Responsibilities and Well-Being During the COVID-19 Lockdown: The Moderating Role of Gender Essentialist Beliefs About Parenthood 

      Thorsteinsen, Kjærsti; Parks-Stamm, Elizabeth J.; Kvalø, Marie; Olsen, Marte; Martiny, Sarah (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-05)
      The present work investigates how the increased domestic responsibilities created by the Spring 2020 lockdown of the COVID-19 pandemic in Norway and gender ideologies relate to the well-being of mothers with elementary school children. In June 2020, we conducted a cross-sectional online study including current and retrospective measures with 180 mothers (M<sub>age</sub> = 39.96 years, SD = 6.11) of ...
    • Professional home care providers' conceptualisations of frailty in the context of home care: A focus group study 

      Voie, Kristin Synnøve; Blix, Bodil Hansen; Helgesen, Ann Karin; Larsen, Toril Agnete; Mæhre, Kjersti Sunde (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-10)
      Background: In Norway, as in many other countries, more people receive health and care services in their homes than before. Home care professionals provide care and support to people with a range of health and care needs. Older home care service users are sometimes referred to as ‘frail’, but the terms ‘frail’ and ‘frailty’ have different meanings in different contexts, and little is known about ...
    • Optimising drug therapy in older patients. Exploring different approaches across the patient pathway 

      Havnes, Kjerstin (Doctoral thesis; Doktorgradsavhandling, 2022-12-14)
      <p><i>Background -</i> Drug therapy contributes to healthy aging but has a key duality: It prolongs and can improve quality of life, but drugs can also cause serious harm. Harm from drugs include falls, cognitive decline, lowered quality of life, hospitalisation, and death. Older patients are especially at risk for harm from drug therapy, therefore optimising drug therapy is imperative for this ...
    • Diverting stomas reduce reoperation rates for anastomotic leak but not overall reoperation rates within 30 days after anterior rectal resection: a national cohort study 

      Myrseth, Elisabeth; Nymo, Linn Såve; Gjessing, Petter Fosse; Norderval, Stig (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-24)
      Purpose A diverting stoma is commonly formed to reduce the rate of anastomotic leak following anterior resection with anastomosis, although some studies question this strategy. The aim of this study was to assess the leak rates and overall complication burden after anterior resection with and without a diverting stoma.<p> <p>Methods A 5-year national cohort with prospectively registered data of ...
    • Normal and unusual days for dietary intake during the 12 months after a breast cancer diagnosis in women 

      Brunvoll, Sonja Hjellegjerde; Flote, Vidar Gordon; Halset, Eline Holli; Bertheussen, Gro Falkener; Skjerven, Helle; Lømo, Jon; Thune, Inger; Hjartåker, Anette (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-24)
      Purpose There are several reasons to report days as being unusual with regard to dietary intake, including special occasions and celebrations. For breast cancer patients during the 12 month post-surgery period, unusual days may also include days that are afected by being a cancer patient. The aim of this study was to study dietary intake on “normal” and “unusual” days, and to study what is reported ...
    • Introduksjon til spesialnummer om etnisk og kulturelt mangfold i helse- og omsorgstjenestene i kommunene 

      Blix, Bodil Hansen; Glasdam, Stinne; Jacobsen, Frode F. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-12)
      Tidligere i år (2022) berørte journalist i Klassekampen Yohan Shanmugaratnam mange med sin lesning av Karpes siste plate Omar Sheriff. I sin tekst skriver han at «Karpe setter ord på migrantenes melankoli», og han skriver om sin foreldregenerasjon, «som bare har jobbet og holdt kjeft, uten at noen har invitert dem til Dagsnytt 18 [norsk nyhets- og debattprogram] for å snakke om ytringsrommet eller ...