Now showing items 2801-2820 of 10433

    • Lifestyle correlates of eight breast cancer-related metabolites: a cross-sectional study within the EPIC cohort 

      His, Mathilde; Viallon, Vivian; Dossus, Laure; Schmidt, Julie A.; Travis, Ruth C.; Gunter, Marc; Overvad, Kim; Kyrø, Cecilie; Tjønneland, Anne; Lécuyer, Lucie; Rothwell, Joseph A.; Severi, Gianluca; Johnson, Theron; Katzke, Verena; Schulze, Matthias B.; Masala, Giovanna; Sieri, Sabina; Panico, Salvatore; Tumino, Rosario; Macciotta, Alessandra; Boer, Jolanda M. A.; Monninkhof, Evelyn; Olsen, Karina Standahl; Nøst, Therese Haugdahl; Sandanger, Torkjel M; Agudo, Antonio; Sánchez, Maria-Jose; Amiano, Pilar; Colorado-Yohar, Sandra; Ardanaz, Eva; Vidman, Linda; Winkvist, Anna; Heath, Alicia K.; Weiderpass, Elisabete; Huybrechts, Inge; Rinaldi, Sabina (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-10)
      Background: Metabolomics is a promising molecular tool for identifying novel etiological pathways leading to cancer. In an earlier prospective study among pre- and postmenopausal women not using exogenous hormones, we observed a higher risk of breast cancer associated with higher blood concentrations of one metabolite (acetylcarnitine) and a lower risk associated with higher blood concentrations of ...
    • The Significance of Traditional Bullying, Cyberbullying, and Mental Health Problems for Middle School Students Feeling Unsafe in the School Environment 

      Fossum, Sturla; Skokauskas, Norbert; Handegård, Bjørn Helge; Hansen, Ketil Lenert; Kyrrestad, Henriette (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-14)
      Feeling safe in school is important for students’ learning, well-being, and quality of life. Variables possibly associated with feeling unsafe in school, such as mental health problems, traditional bullying, cyberbullying, and various health problems, were explored. Altogether, 2,028 adolescents (M<sub>age</sub> = 14 years, 50% boys) from 72 middle schools in northern Norway were respondents. Being ...
    • Restorative treatment decisions for carious lesions: Do Russian dentists and dental students apply minimal intervention dentistry? 

      Drachev, Sergei Nikolaevich; Galieva, Alexandra S.; Yushmanova, Tatiana N.; Polivanaya, Elena A.; Stangvaltaite-Mouhat, Lina; Al-Mahdi, Rania; Leinonen, Jukka; Stein, Linda; Davidova, Nadezhda G.; Al-Haroni, Mohammed (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-15)
      <p><b>Background</b> The concept of minimal intervention dentistry (MID) includes both delayed restorative treatment and conservative caries removal, and is now recognised as an evidence-based approach for dental caries management. In order to determine if dental professionals in Russia are incorporating this concept into their clinical practice, we investigated the restorative treatment decisions ...
    • No improvement of sleep from vitamin D supplementation: insights from a randomized controlled trial 

      Larsen, Anette Uhlving; Hopstock, Laila Arnesdatter; Jorde, Rolf; Grimnes, Guri (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-19)
      <i><p>Background</i> Vitamin D has been linked to sleep health in observational studies. Data from randomized controlled trials (RCTs) with vitamin D is scarce. <i><p>Methods</i> This study presents the results of a secondary analysis of 189 vitamin D insufficient participants (47.1% women) in a previously performed RCT, of which 92 were randomized to vitamin D (100,000 IU (2500 μg) as a ...
    • Måleegenskaper ved den norske versjonen av Youth Self Report (YSR) 

      Reedtz, Charlotte; Løvereide, Stine (Journal article; Tidsskriftartikkel; Peer reviewed, 2021)
      Youth Self Report (YSR) er et av spørreskjemaene som inngår i Achenbach´s System of Empirically Based Assessment (ASEBA), i tillegg til Child Behavior Checklist (CBCL) og Teacher´s Report Form (TRF). YSR måler kompetanse, adaptiv fungering og atferdsmessige vanskeområder for aldersgruppen 11–18 år. YSR opererer med en total skår, mål på internaliserende og eksternaliserende atferd, samt åtte ulike ...
    • Pasienter med strømgjennomgang fra lavspenning henvist til et akuttmottak 

      Svendsen, Trude Beathe; Bærheim, Dina; Dale, Jostein; Goffeng, Lars Ole; Vesterfjell, Svend Peder; Ofstad, Eirik Hugaas; Næss-Pleym, Lars E.; Bjørnsen, Lars Petter Bache-Wiig (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-13)
      <p><b>BAKGRUNN</b> Pasienter utsatt for strøm henvises ofte til akuttmottaket, men det er ulike retningslinjer for hvordan disse bør håndteres. Vi beskriver her pasienter med strømgjennomgang fra lavspenning i akuttmottaket ved St. Olavs hospital. <p><b>METODE OG MATERIALE</b> Retrospektive data fra pasienter henvist til akuttmottaket etter strømgjennomgang fra lavspenning (< 1 000 volt) i ...
    • Måleegenskaper ved den norske versjonen av Olweus spørreskjema om mobbing (Olweusundersøkelsen) 

      Solberg, Mona Elin; Martinussen, Monica (Journal article; Tidsskriftartikkel; Peer reviewed, 2021)
      Olweus spørreskjema om mobbing for elever ble utviklet på 1980-tallet og brukes til å kartlegge mobbing i skolen basert på elevers selvrapportering. I Norge brukes skjemaet først og fremst i grunnskolen på 4. til 10. trinn. Skjemaet ble utviklet på norsk, men er senere oversatt til flere språk, inkludert engelsk: The Olweus Bully/Victim Questionnaire (OBVQ; Olweus, 1986) og The Revised Olweus ...
    • Randomized Trial of Interleukin-6 Receptor Inhibition in Patients With Acute ST-Segment Elevation Myocardial Infarction 

      Broch, Kaspar; Anstensrud, Anne Kristine; Woxholt, Sindre; Sharma, Kapil Kishore; Tøllefsen, Ingvild Maria; Bendz, Bjørn; Aakhus, Svend; Ueland, Thor; Amundsen, Brage H.; Damås, Jan Kristian; Berg, Erlend; Bjørkelund, Elisabeth; Bendz, Christina; Hopp, Einar; Kleveland, Ola; Stensæth, Knut Haakon; Opdahl, Anders; Kløw, Nils-Einar; Seljeflot, Ingebjørg; Andersen, Geir Øystein; Wiseth, Rune; Aukrust, Pål; Gullestad, Lars (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-12)
      <p><i>Background - </i>Prompt myocardial revascularization with percutaneous coronary intervention (PCI) reduces infarct size and improves outcomes in patients with ST-segment elevation myocardial infarction (STEMI). However, as much as 50% of the loss of viable myocardium may be attributed to the reperfusion injury and the associated inflammatory response. <p><i>Objectives - </i>This study sought ...
    • The psychometric properties and norm data of the Norwegian military personality inventory (NMPI) 

      Nordmo, Morten; Skoglund, Tom Hilding; Lang-Ree, Ole Christian; Austad, Sara Kasia; Martinussen, Monica (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-16)
      The five-factor structure is a well-established model for personality. The five traits covary with job-performance and work-relevant outcomes. The practical administration of existing big-five measurement scales is, however, somewhat limited, in a Norwegian setting, as existing scales are impractically large or have unknown psychometric properties. Because of this, a new brief Norwegian personality ...
    • Dietary advanced glycation end-products and colorectal cancer risk in the European prospective investigation into cancer and nutrition (EPIC) study 

      Aglago, Elom K.; Mayén, Ana-Lucia; Knaze, Viktoria; Freisling, Heinz; Fedirko, Veronika; Hughes, David J.; Jiao, Li; Eriksen, Anne Kirstine; Tjønneland, Anne; Boutron-Ruault, Marie-Christine; Rothwell, Joseph A.; Severi, Gianluca; Kaaks, Rudolf; Katzke, Verena; Schulze, Matthias B.; Birukov, Anna; Palli, Domenico; Sieri, Sabina; de Magistris, Maria Santucci; Tumino, Rosario; Ricceri, Fulvio; Bueno-De-Mesquita, Bas; Derksen, Jeroen W.G.; Skeie, Guri; Gram, Inger Torhild; Sandanger, Torkjel M; Quirós, J. Ramón; Lujan-Barroso, Leila; Sánchez, Maria-Jose; Amiano, Pilar; Chirlaque, María-Dolores; Barricarte, Aurelio; Johansson, Ingegerd; Manjer, Jonas; Perez-Cornago, Aurora; Weiderpass, Elisabete; Gunter, Marc; Heath, Alicia K.; Schalkwijk, Casper G.; Jenab, Mazda (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-08)
      Dietary advanced glycation end-products (dAGEs) have been hypothesized to be associated with a higher risk of colorectal cancer (CRC) by promoting inflammation, metabolic dysfunction, and oxidative stress in the colonic epithelium. However, evidence from prospective cohort studies is scarce and inconclusive. We evaluated CRC risk associated with the intake of dAGEs in the European Prospective ...
    • An artificial neural network approach integrating plasma proteomics and genetic data identifies PLXNA4 as a new susceptibility locus for pulmonary embolism 

      Razzaq, Misbah; Iglesias, Maria Jesus; Ibrahim-Kosta, Manal; Goumidi, Louisa; Soukarieh, Omar; Proust, Carole; Roux, Maguelonne; Suchon, Pierre; Boland, Anne; Daiain, Delphine; Olaso, Robert; Havervall, Sebastian; Thalin, Charlotte; Butler, Lynn; Deleuze, Jean-François; Odeberg, Jacob; Morange, Pierre-Emmanuel; Trégouët, David-Alexandre (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-07)
      Venous thromboembolism is the third common cardiovascular disease and is composed of two entities, deep vein thrombosis (DVT) and its potential fatal form, pulmonary embolism (PE). While PE is observed in~ 40% of patients with documented DVT, there is limited biomarkers that can help identifying patients at high PE risk. To fll this need, we implemented a two hidden-layers artifcial neural ...
    • Dietary fatty acids, macronutrient substitutions, food sources and incidence of coronary heart disease: Findings from the EPIC-CVD case-cohort study across nine european countries 

      Steur, Marinka; Johnson, Laura; Sharp, Stephen J.; Imamura, Fumiaki; Sluijs, Ivonne; Key, Timothy J.; Wood, Angela M.; Chowdhury, Rajiv; Guevara, Marcela; Jakobsen, Marianne Uhre; Johansson, Ingegerd; Koulman, Albert; Overvad, Kim; Sánchez, Maria-José; van der Schouw, Yvonne T.; Trichopoulou, Antonia; Weiderpass, Elisabete; Wennberg, Maria; Zheng, Ju-Sheng; Boeing, Heiner; Boer, Jolanda M. A.; Boutron-Ruault, Marie-Christine; Ericson, Ulrika; Heath, Alicia K.; Huybrechts, Inge; Imaz, Liher; Kaaks, Rudolf; Krogh, Vittorio; Kühn, Tilman; Kyrø, Cecilie; Masala, Giovanna; Melander, Olle; Moreno-Iribas, Conchi; Panico, Salvatore; Quirós, José R.; Rodríguez-Barranco, Miguel; Sacerdote, Carlotta; Santiuste, Carmen; Skeie, Guri; Tjønneland, Anne; Tumino, Rosario; Monique Verschuren, Verschuren; Zamora-Ros, Raúl; Dahm, Christina C.; Perez-Cornago, Aurora; Schulze, Matthias B.; Tong, Tammy Y.N.; Riboli, Elio; Wareham, Nick; Danesh, John; Butterworth, Adam S.; Forouhi, Nita G. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-07)
      BACKGROUND: There is controversy about associations between total dietary fatty acids, their classes (saturated fatty acids [SFAs], monounsaturated fatty acids, and polyunsaturated fatty acids), and risk of coronary heart disease (CHD). Specifically, the relevance of food sources of SFAs to CHD associations is uncertain.<p> METHODS AND RESULTS: We conducted a case-cohort study involving 10 529 ...
    • A single-cell type transcriptomics map of human tissues 

      Karlsson, Max; Cheng, Zhang; Mear, Lorén; Zhong, Wen; Digre, Andreas; Katona, Barbola; Sjöstedt, Evelina; Butler, Lynn; Odeberg, Jacob; Dusart, Philip James; Edfors, Fredrik; Oksvold, Per; von Feilitzen, Kalle; Zwahlen, Martin; Arif, Muhammad; Altay, Ozlem; Li, Xiangyu; Ozcan, Mehmet; Mardinoglu, Adil; Fagerberg, Linn; Mulder, Jan; Luo, Younglun; Ponten, Fredrik; Uhlén, Mathias; Lindskog, Cecilia (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-28)
      Advances in molecular profiling have opened up the possibility to map the expression of genes in cells, tissues, and organs in the human body. Here, we combined single-cell transcriptomics analysis with spatial antibodybased protein profiling to create a high-resolution single–cell type map of human tissues. An open access atlas has been launched to allow researchers to explore the expression of ...
    • Heavy decline of the largest European Arctic Skua Stercorarius parasiticus colony: interacting effects of food shortage and predation 

      van Bemmelen, Rob; Schekkermann, Hans; Hin, Vincent; Pot, Morrison; Janssen, Kirstin; Ganther, Barbara; Rösner, Hans-Ulrich; Tulp, Ingrid (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-24)
      Capsule: The number of breeding pairs of Europe’s largest Arctic Skua Stercorarius parasiticus colony at Slettnes, Norway, showed a dramatic decline of at least 50% over two decades, with food shortage in four years and increasing predation by Red Fox Vulpes vulpes leading to total breeding failure in five out of six recent study years.<p> Aims: To document the decline of Europe’s largest Arctic ...
    • Family correlates of emotional and behavioral problems in Nepali school children 

      Ma, Jasmine (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-18)
      Background<p> <p>There is a substantial gap in our knowledge about family correlates of child emotional and behavioral problems in low- and middle-income countries (LMIC). The present study contributes to filling this gap by examining such correlates in a larger population study in Nepal.<p> Methods<p> <p>Our study is a cross-sectional, observational study among 3840 Nepali children aged 6–18 ...
    • LTX-315-enabled, radiotherapy-boosted immunotherapeutic control of breast cancer by NK cells 

      Yamazaki, Takahiro; Wennerberg, Erik; Hensler, Michal; Buqué, Aitziber; Kraynak, Jeffrey; Fucikova, Jitka; Zhou, Xi Kathy; Rekdal, Øystein; Demaria, Sandra; Galluzzi, Lorenzo (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-10)
      LTX-315 is a nonameric oncolytic peptide in early clinical development for the treatment of solid malignancies. Preclinical and clinical evidence indicates that the anticancer properties of LTX-315 originate not only from its ability to selectively kill cancer cells, but also from its capacity to promote tumortargeting immune responses. Here, we investigated the therapeutic activity and immunological ...
    • An in-depth implementation study of the Greenlandic parenting program MANU’s initial stages of implementation 

      Ingemann, Christine; Kuhn, Rikke Louise; Kvernmo, Siv; Tjørnhøj-Thomsen, Tine; Larsen, Christina Viskum Lytken (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-22)
      In Greenland, the universal parenting programme MANU was developed in 2016. After documenting the initial years of MANU’s implementation, this study aimed to identify implementation determinants focusing on i) which context MANU was conceptualised in and how it was developed and ii) how MANU was implemented and initially received in the healthcare system. A qualitative in-depth implementation ...
    • Clinical and economic impact of universal varicella vaccination in Norway: A modeling study 

      Pawaskar, Manjiri; Burgess, Colleen; Pillsbury, Matthew; Wisløff, Torbjørn (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-08)
      Background<p> <p>Norway has not implemented universal varicella vaccination, despite the considerable clinical and economic burden of varicella disease.<p> Methods<p> <p>An existing dynamic transmission model of varicella infection was calibrated to age-specific seroprevalence rates in Norway. Six two-dose vaccination strategies were considered, consisting of combinations of two formulations ...
    • Perspectives for systems biology in the management of tuberculosis 

      Kontsevaya, Irina; Lange, Christoph; Comella-Del-barrio, Patricia; Coarfa, Cristian; Dinardo, Andrew R.; Gillespie, Stephen H.; Hauptmann, Matthias; Leschczyk, Christoph; Mandalakas, Anna M.; Martinecz, Antal; Merker, Matthias; Niemann, Stefan; Reimann, Maja; Rzhepishevska, Olena; Schaible, Ulrich E.; Scheu, Katrin M.; Schurr, Erwin; Abel zur Wiesch, Pia; Heyckendorf, Jan (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-25)
      Standardised management of tuberculosis may soon be replaced by individualised, precision medicineguided therapies informed with knowledge provided by the field of systems biology. Systems biology is a rapidly expanding field of computational and mathematical analysis and modelling of complex biological systems that can provide insights into mechanisms underlying tuberculosis, identify novel ...
    • Public health nursing in Ireland and Norway: A comparative analysis 

      Mulcahy, Helen; Leahy-Warren, Patricia; Laholt, Hilde; Philpott, Lloyd Frank; Bergvoll, Lise-Marie; Clancy, Anne (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-23)
      <p<i>Background:</i> Public health, primary healthcare, and nursing are founding principles of public health nursing. Thus, the underpinning curriculum needs to reflect these core principles. Public health nursing educators sought to delve deeper into curricula and training of public health nurse (PHNs)in Ireland and Norway. <p><i>Objective:</i> To compare PHNs’ educational training in Ireland and ...