Now showing items 3461-3480 of 10438

    • The Educational Gradient in Intake of Energy and Macronutrients in the General Adult and Elderly Population: The Tromsø Study 2015–2016 

      Nilsen, Linn; Hopstock, Laila Arnesdatter; Skeie, Guri; Grimsgaard, Sameline; Lundblad, Marie Wasmuth (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-28)
      Worldwide, there are socioeconomic inequalities in health and diet. We studied the relationship between education and nutrient intake in 11,302 women and men aged 40–96 years who participated in the seventh survey of the population-based Tromsø Study (2015–2016), Norway (attendance 65%). Diet was assessed using a validated food-frequency questionnaire. We examined the association between education ...
    • Prevalence, diversity and transferability of the Tn916-Tn1545 family ICE in oral streptococci 

      Lunde, Tracy Munthali; Hjerde, Erik; Al-Haroni, Mohammed (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-15)
      <i>Background</i>: The Tn<i>916</i>-Tn<i>1545</i> family of Integrative Conjugative Elements (ICE) are mobile genetic elements (MGEs) that play a role in the spread of antibiotic resistance genes. The Tn<i>916</i> harbors the tetracycline resistance gene <i>tet</i>(M) and it has been reported in various bacterial species. The increase in the levels of tetracycline resistance among oral streptococci ...
    • How physicians manage medical uncertainty: A qualitative study and conceptual taxonomy 

      Han, Paul K.J.; Strout, Tania D.; Gutheil, Caitlin; Germann, Carl; King, Brian; Ofstad, Eirik Hugaas; Gulbrandsen, Pål; Trowbridge, Robert (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-01)
      Background - Medical uncertainty is a pervasive and important problem, but the strategies physicians use to manage it have not been systematically described.<p> <p>Objectives - To explore the uncertainty management strategies employed by physicians practicing in acute-care hospital settings and to organize these strategies within a conceptual taxonomy that can guide further efforts to understand ...
    • Demografisk utvikling og potensialet for uformell omsorg i Norge 

      Blix, Bodil Hansen; Stalsberg, Helge; Moholt, Jill-Marit (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-11)
      Bakgrunn: Myndighetene har forventninger om at bidrag fra pårørende og frivillige i omsorg for hjemmeboende eldre skal opprettholdes på dagens nivå eller økes i fremtiden. I artikkelen undersøker vi potensialet for uformell omsorg med utgangspunkt i den demografiske utviklingen frem mot 2040. Metode: Med utgangspunkt i folketall fra 2018 og Statistisk sentralbyrås befolkningsframskrivinger 2018–2040 ...
    • Factors associated with the establishment of new occupational therapist positions in Norwegian municipalities after the Coordination reform 

      Maass, Ruca Elisa Katrin; Bonsaksen, Tore; Gramstad, Astrid; Sveen, Unni; Stigen, Linda; Arntzen, Cathrine; Horghagen, Sissel (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-16)
      Community-based occupational therapy is an increasingly important domain of work for occupational therapists. In Norway, this has been emphasized by the Coordination reform (2012), which assigned municipalities increased responsibility to protect and promote the health of their inhabitants. However, even if approximately 400 positions have been established between 2012 and 2017, little is known ...
    • Piggybacking on Niche Adaptation Improves the Maintenance of Multidrug-Resistance Plasmids 

      Kloos, Julia Maria; Gama, João Alves; Hegstad, Joachim; Samuelsen, Ørjan; Johnsen, Pål Jarle (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-24)
      The persistence of plasmids in bacterial populations represents a puzzling evolutionary problem with serious clinical implications due to their role in the ongoing antibiotic resistance crisis. Recently, major advancements have been made toward resolving this “plasmid paradox” but mainly in a nonclinical context. Here, we propose an additional explanation for the maintenance of multidrug‐resistance ...
    • Adolescents’ experiences of the information they received about the coronavirus (Covid-19) in Norway: a cross-sectional study 

      Kaiser, Sabine; Kyrrestad, Henriette; Martinussen, Monica (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-16)
      Background - In the first months of the coronavirus (Covid-19) pandemic, many countries took radical prevention measures. Authorities had to communicate with the public regularly to explain and ensure compliance with these measures and promote safety. The information given by authorities was mainly developed for adults, but children and adolescents may have different needs when it comes to information. ...
    • Fatigue in young adults with juvenile idiopathic arthritis 18 years after disease onset: data from the prospective Nordic JIA cohort 

      Arnstad, Ellen Dalen; Glerup, Mia; Rypdal, Veronika Gjertsen; Peltoniemi, Suvi; Fasth, Anders; Nielsen, Susan; Zak, Marek; Aalto, Kristiina; Berntson, Lillemor; Nordal, Ellen Berit; Herlin, Troels; Romundstad, Pål Richard; Rygg, Marite (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-12)
      Background: To study fatigue in young adults with juvenile idiopathic arthritis (JIA) 18 years after disease onset, and to compare with controls. Methods: Consecutive children with onset of JIA between 1997 and 2000, from geographically defined areas of Norway, Sweden, Denmark and Finland were followed for 18 years in a close to population-based prospective cohort study. Clinical features, ...
    • Evaluation of Merkel Cell Polyomavirus DNA in Tissue Samples from italian Patients With Diagnosis of MCC 

      Prezioso, Carla; Carletti, Raffaella; Obregon, Francisco; Piacentini, Francesca; Maricone, Anna Maria; Soda, Giuseppe; Moens, Ugo; Di Gioia, Cira; Pietropaolo, Valeria (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-05)
      Because the incidence of Merkel cell carcinoma (MCC) has increased significantly during the last 10 years and it is recognized that Merkel cell polyomavirus (MCPyV) and ultraviolet (UV) radiation represent two different etiological inputs sharing clinical, histopathological, and prognostic similar features, although with different prognosis, this study investigated the detection of MCPyV in skin and ...
    • Clinical reasoning in traditional medicine exemplified by the clinical encounter of Korean medicine: a narrative review 

      Kim, Tae-Hun; Alræk, Terje; Bian, Zhao-Xiang; Birch, Stephen; Bovey, Mark; Lee, Juah; Lee, Myeong Soo; Robinson, Nicola; Zaslawski, Christopher (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08-11)
      Background - Clinical reasoning is generally defined as a way of thinking about diagnostic or therapeutic decision making in clinical practice. Different cognitive models have been proposed for the clinical reasoning process which takes place during the clinical encounter with a patient. This may have similarities with similar approaches used in Traditional Korean Medicine (TKM). Jinchal, the clinical ...
    • “When I sleep poorly, it impacts everything”: An exploratory qualitative investigation of stress and sleep in junior endurance athletes 

      Hrozanova, Maria; Firing, Kristian; Moen, Frode (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-15)
      On their journeys toward senior athletic status, junior endurance athletes are faced with a multitude of stressors. How athletes react to stressors plays a vital part in effective adaptation to the demanding, ever-changing athletic environment. Sleep, the most valued recovery strategy available to athletes, has the potential to influence and balance athletic stress, and enable optimal functioning. ...
    • High prevalence of multidrug resistant ESBL- and plasmid mediated AmpC-producing clinical isolates of Escherichia coli at Maputo Central Hospital, Mozambique 

      Estaleva, Calvina E.L.; Zimba, Tomas F.; Sekyere, John Osei; Govinden, Usha; Chenia, Hafizah Y.; Simonsen, Gunnar S.; Haldorsen, Bjørg; Essack, Sabiha Y.; Sundsfjord, Arnfinn (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-06)
      Background: Epidemiological data of cephalosporin-resistant Enterobacterales in Sub-Saharan Africa is still restricted,and in particular in Mozambique. The aim of this study was to detect and characterize extended-spectrum β-lactamase (ESBL) - and plasmid-mediated AmpC (pAmpC)-producing clinical strains of Escherichia coli at Maputo Central Hospital (MCH), a 1000-bed reference hospital in Maputo, ...
    • Tinnitus and associations with chronic pain: The population-based Tromsø Study (2015-2016) 

      Ausland, Jannike Heyerdahl-Larsen; Engdahl, Bo Lars; Oftedal, Bente Margaret; Steingrímsdóttir, Ólöf Anna; Nielsen, Christopher Sivert; Hopstock, Laila Arnesdatter; Johnsen, Magnar; Friborg, Oddgeir; Rosenvinge, Jan H; Eggen, Anne Elise; Krog, Norun Hjertager (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-02)
      Tinnitus and pain have many similarities. Both are subjective sensations that may turn chronic, they are often accompanied by hypersensitivity in their respective sensory system, and overlapping brain changes have been observed. Since no population study has examined the empirical association between chronic pain and tinnitus, the present study aimed to explore the relationship in a general adult ...
    • A scoping review to map the concept, content, and outcome of wilderness programs for childhood cancer survivors 

      Jong, Mats; Lown, E. Anne; Schats, Winnie; Mills, Michelle L.; Otto, Heather Rose; Gabrielsen, Leiv Einar; Jong, Miek (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-06)
      Objectives - Systematic mapping of the concept, content, and outcome of wilderness programs for childhood cancer survivors.<p> <p>Design - Scoping review.<p> <p>Search strategy - Searches were performed in 13 databases and the grey literature. Included studies describe participation of childhood cancer survivors in wilderness programs where the role of nature had a contextual and therapeutic ...
    • DNA hypo-methylation facilitates anti-inflammatory responses in severe ulcerative colitis 

      Taman, Hagar; Fenton, Christopher Graham; Anderssen, Endre; Florholmen, Jon; Paulssen, Ruth H (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-01)
      Severe ulcerative colitis (UC) is a potentially life-threatening disease with a potential colorectal cancer (CRC) risk. The aim of this study was to explore the relationship between transcriptomic and genome-wide DNA methylation profiles in a well-stratified, treatment-naïve severe UC patient population in order to define specific epigenetic changes that could be responsible for the grade of disease ...
    • The changing alcohol drinking patterns among older adults show that women are closing the gender gap in more frequent drinking: The Tromsø Study, 1994 – 2016 

      Stelander, Line Tegner; Høye, Anne; Bramness, Jørgen Gustav; Selbæk, Geir; Lunde, Linn Heidi; Wynn, Rolf; Grønli, Ole Kristian (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-26)
      Background - As the population of older adults continues to grow, changes in alcohol consumption are important to monitor because an increase may have public health consequences. Rates of alcohol use vary with geographical location. The aim of this study was to examine trends in alcohol consumption among older adults in a geographically defined area in Norway, especially changing sex differences in ...
    • Severe hypercalcemia caused by parathyroid hormone in a rectal cancer metastasis: a case report 

      Brun, Vegard Heimly; Knutsen, Erik; Stenvold, Helge; Halvorsen, Hanne (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-07)
      Background - Hypercalcemia of malignancy is relatively common in several cancers. However, in colorectal cancer, paraneoplastic phenomena that cause hypercalcemia is uncommon. In the few cases that are reported, secretion of parathyroid hormone-related peptide mediates the effect. We describe the first case of severe hypercalcemia mediated by intact parathyroid hormone secretion from a bone metastasis ...
    • Resonance frequency is not always stable over time and could be related to the inter‑beat interval 

      Capdevila, Lluis; Parrado, Eva; Ramos-Castro, Juan; Zapata-Lamana, Rafael; Lalanza, Jaume F (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-16)
      Heart Rate Variability Biofeedback (HRVB) is based on breathing at an optimal rate (or resonance frequency, RF) corresponding to the respiratory sinus arrhythmia (RSA). Our aim is to check whether the RF is a stable factor and analyse the HRV parameters individually per each breathing rate, comparing it with free slow breathing. A sample of 21 participants were trained in a test–retest HRVB ...
    • Serum alanine aminotransferase activity and risk factors for cardiovascular disease in a Caucasian population: the Tromsø study 

      Bekkelund, Svein Ivar (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-13)
      Background - High and low levels of serum alanine aminotransferase (ALT) are both associated with cardiovascular diseases (CVD) risks especially in elderly, but the mechanisms are less known. This study investigated associations between ALT and CVD risk factors including effects of sex and age in a Caucasian population.<p> <p>Methods - Cross-sectional data were analysed sex-stratified in 2555 men ...
    • Gene expression in blood reflects smoking exposure among cancer-free women in the Norwegian Women and Cancer (NOWAC) postgenome cohort 

      Baiju, Nikita; Sandanger, Torkjel M; Sætrom, Pål; Nøst, Therese Haugdahl (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-12)
      Active smoking has been linked to modulated gene expression in blood. However, there is a need for a more thorough understanding of how quantitative measures of smoking exposure relate to differentially expressed genes (DEGs) in whole-blood among ever smokers. This study analysed microarray-based gene expression profiles from whole-blood samples according to smoking status and quantitative measures ...