Now showing items 3481-3500 of 10438

    • Inside the clockwork of the ECHO factorial trial: A conceptual model with proposed mediators for prevention of emotional problems in children 

      Ingul, Jo Magne; Martinsen, Kristin; Adolfsen, Frode; Sund, Anne Mari; Ytreland, Kristin; Bania, Elisabeth Valmyr; Lisøy, Carina; Rasmussen, Lene-Mari Potulski; Haug, Ida Mari; Patras, Joshua; Collins, Linda M.; Kendall, Phillip C.; Neumer, Simon-Peter (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-21)
      Having interventions that are not only evidence-based and effective but also cost-effective and efficient is important for the prevention and treatment of child and adolescent emotional problems. A randomized clinical trial (RCT) tests the totalinterventions effect but does not address specific components of the intervention. In this article the hypothesis and a conceptual model of the ECHO study ...
    • Change in quality of life and self-esteem in a randomized controlled CBT study for anxious and sad children: can targeting anxious and depressive symptoms improve functional domains in schoolchildren? 

      Martinsen, Kristin; Rasmussen, Lene-Mari Potulski; Wentzel-Larsen, Tore; Holen, Solveig; Sund, Anne Mari; Pedersen, Marit Løtveit; Løvaas, Mona Elisabeth S; Patras, Joshua; Adolfsen, Frode; Neumer, Simon-Peter (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-21)
      <i>Background</i> - Quality of life and self-esteem are functional domains that may suffer when having mental problems. In this study, we examined the change in quality of life and self-esteem when targeting anxious and depressive symptoms in school children (8–12 years) using a CBT-based transdiagnostic intervention called EMOTION, Kids Coping with anxiety and depression. The aim of this study was ...
    • La physiothérapie comme actrice d’un système de santé plus durable 

      Ferchichi-Barbey, Sylvie; Poget, Fanny; Maric, Filip; Christe, Guillaume (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06)
      <p>Context: Population health and environmental crisis are intimately linked. The health care community has an important responsibility to integrate environmental issues into its actions. <p>Objective: This article proposes approaches to integrate environmental and sustainability issues into physiotherapy practice. <p>Development: Actions aiming at promoting high-value care, communicating about ...
    • MercuNorth – monitoring mercury in pregnant women from the Arctic as a baseline to assess the effectiveness of the Minamata Convention 

      Adlard, Bryan; Lemire, Mélanie; Bonefeld-Jørgensen, Eva Cecilie; Long, Manhai; Ólafsdóttir, Kristín; Odland, Jon Øyvind; Rautio, Arja; Myllynen, Päivi; Sandanger, Torkjel M; Dudarev, Alexey A.; Bergdahl, Ingvar A.; Wennberg, Maria; Berner, James; Ayotte, Pierre (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-03)
      Exposure to mercury (Hg) is a global concern, particularly among Arctic populations that rely on the consumption of marine mammals and fish which are the main route of Hg exposure for Arctic populations.The MercuNorth project was created to establish baseline Hg levels across several Arctic regions during the period preceding the Minamata Convention. Blood samples were collected from 669 pregnant ...
    • Real-life evaluation of histologic scores for Ulcerative Colitis in remission 

      Arkteg, Christian Børde; Sørbye, Sveinung Wergeland; Riis, Lene Buhl; Dalen, Stig Manfred; Florholmen, Jon; Goll, Rasmus (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-08)
      Background - Histological evaluation of ulcerative colitis (UC) patients has been debated ever since the first description of the disease and its role in follow-up has never been fully established. Recent evidence suggests an added benefit in accuracy when evaluating if the patient is in remission. Unfortunately, there are several different histological indices, and it is difficult to compare outcomes ...
    • KI and WU Polyomavirus in Respiratory Samples of SARS-CoV-2 Infected Patients 

      Prezioso, Carla; Moens, Ugo; Oliveto, Giuseppe; Brazzini, Gabriele; Piacentini, Francesca; Frasca, Federica; Viscido, Agnese; Scordio, Mirko; Guerrizio, Giuliana; Rodio, Donatella Maria; Pierangeli, Alessandra; d'Ettorre, Gabriella; Turriziani, Ombretta; Antonelli, Guido; Scagnolari, Carolina; Pietropaolo, Valeria (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-09)
      Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) has been declared a global pandemic. Our goal was to determine whether co-infections with respiratory polyomaviruses, such as Karolinska Institutet polyomavirus (KIPyV) and Washington University polyomavirus (WUPyV) occur in SARS-CoV-2 infected patients. Oropharyngeal swabs from 150 individuals, 112 symptomatic COVID-19 patients and 38 ...
    • From Paper to E-Prescribing of Multidose Drug Dispensing: A Qualitative Study of Workflow in a Community Care Setting 

      Jøsendal, Anette Vik; Bergmo, Trine Strand (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-16)
      E-prescribing is now widespread and, in some countries, has completely replaced paper prescriptions. In Norway, almost all prescribing is electronic, except for multidose drug dispensing (MDD), which is still sent to the pharmacy by fax or ordinary mail. MDD is an adherence aid used by one-third of all patients receiving home care services. In this paper, we present results from a qualitative study ...
    • IgE-mediated peanut allergy: Current and novel predictive biomarkers for clinical phenotypes using multi-omics approaches 

      Czolk, Rebecca; Klueber, Julia; Sørensen, Martin; Wilmes, Paul; Codreanu-Morel, Françoise; Skov, Per Stahl; Hilger, Christiane; Bindslev-Jensen, Carsten; Ollert, Markus; Kuehn, Annette (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-28)
      Food allergy is a collective term for several immune-mediated responses to food. IgE-mediated food allergy is the best-known subtype. The patients present with a marked diversity of clinical profiles including symptomatic manifestations, threshold reactivity and reaction kinetics. In-vitro predictors of these clinical phenotypes are evasive and considered as knowledge gaps in food allergy diagnosis ...
    • The self-management work of food hypersensitivity 

      Jakobsen, Monika Dybdahl; Obstfelder, Aud; Braaten, Tonje; Abelsen, Birgit (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-05)
      Background - Food hypersensitivity (FH) has received considerable attention in the scientific community in recent years. However, little attention has been given to the efforts people make to manage their FH. We aimed to explore these efforts by using Normalization Process Theory, which is a conceptual framework formerly used to describe the self-management ‘work’ of long-term conditions.<p> <p>Methods ...
    • Communication and information needs about complementary and alternative medisine: a qualitative study of parents of children with cancer 

      Stub, Trine; Quandt, Sara A.; Kristoffersen, Agnete E.; Jong, Miek C.; Arcury, Thomas A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-08)
      Background - Many parents choose support such as Complementary and Alternative Medicine (CAM) for themselves and their children who have cancer. The aim of this paper is to describe, how parents who have children with cancer communicated with conventional health care providers about CAM, and what types and sources of information they would like to receive about CAM when the child was ill.<p> <p>Method ...
    • Preservation of person-centered care through videoconferencing for patient follow-up during the covid-19 pandemic:case study of a multidisciplinary care team 

      Silsand, Line; Severinsen, Gro-Hilde; Berntsen, Gro (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-05)
      Background: The Patient-Centered Team (PACT) focuses on the transitional phase between hospital and primary care for older patients in Northern Norway with complex and long-term needs. PACT emphasizes a person-centered care approach whereby the sharing of power and the patient’s response to “What matters to you?” drive care decisions. However, during the COVID-19 pandemic, videoconferencing was the ...
    • Neuroinflammatory processes are augmented in mice overexpressing human heat-shock protein B1 following ethanol-induced brain injury 

      Dukay, Brigitta; Walter, Fruzsina; Vigh, Judit; Barabasi, Beata; Hajdu, Petra; Balassa, Tamas; Migh, Ede; Kincses, Andras; Hoyk, Zsofia; Szogi, Titanilla; Borbely, Emoke; Csoboz, Balint; Horvath, Peter; Fulop, Livia; Penke, Botond; Vigh, Laszlo; Deli, Maria; Santha, Mikos; Toth, Melinda (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-10)
      Background - Heat-shock protein B1 (HSPB1) is among the most well-known and versatile member of the evolutionarily conserved family of small heat-shock proteins. It has been implicated to serve a neuroprotective role against various neurological disorders via its modulatory activity on inflammation, yet its exact role in neuroinflammation is poorly understood. In order to shed light on the exact ...
    • Adherence to prescription guidelines and achievement of treatment goals among persons with coronary heart disease in Tromsø 7 

      Pedersen, Elisabeth; Garcia, Beate Hennie; Halvorsen, Kjell H.; Eggen, Anne Elise; Schirmer, Henrik; Waaseth, Marit (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-21)
      Background - Adherence to clinical practice guidelines for coronary heart disease (CHD) reduces morbidity, mortality and treatment costs. We aimed to describe and compare adherence to prescription guidelines for persons with CHD, and explore its association with treatment goal achievement.<p> <p>Method - We included all participants reporting myocardial infarction, angina, percutaneous coronary ...
    • Sámi and Norwegian nurses’ perspectives on nursing care of Sámi patients: a focus group study on culturally safe nursing 

      Engnes, Janne Isaksen; Sivertsen, Nina; Bongo, Berit Andersdatter; Mehus, Grete (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-01)
      Sámi people report less satisfaction with healthcare services than the majority population in Norway, and report that they seldom encounter culturally adapted health services. This study investigates Sámi and Norwegian nurses’ perspectives on culturally respectful and appropriate caring for Sámi patients in northern Norway. Six focus groups were conducted: three with Sámi-speaking nurses (n = 13) ...
    • Tenecteplase in wake-up ischemic stroke trial: Protocol for a randomized-controlled trial 

      Roaldsen, Melinda Berg; Lindekleiv, Haakon; Eltoft, Agnethe; Jusufovic, Mirza; Søyland, Mary-Helen; Petersson, Jesper; Indredavik, Bent; Tveiten, Arnstein; Putaala, Jukka; Christensen, Hanne; Kõrv, Janika; Jatužis, Dalius; Engelter, Stefan T.; Marco De Marchis, Gian; Wilsgaard, Tom; Werring, David; Robinson, Thompson; Mathiesen, Ellisiv B.; Berge, Eivind (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-14)
      <p>Background: Patients with wake-up ischemic stroke who have evidence of salvageable tissue on advanced imaging can benefit from intravenous thrombolysis. It is not known whether patients who do not fulfil such imaging criteria might benefit from treatment, but studies indicate that treatment based on non-contrast CT criteria may be safe. Tenecteplase has shown promising results in patients with ...
    • Rat ultrasonic vocalizations and novelty-induced social and non-social investigation behavior in a seminatural environment 

      Heinla, Indrek; Chu, Xi; Ågmo, Anders j; Snoeren, Eelke (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-03)
      Although rats are known to emit ultrasonic vocalizations (USVs), it remains unclear whether these calls serve an auditory communication purpose. For USVs to be part of communication, the vocal signals will need to be a transfer of information between two or more conspecifics, and with the possibility to induce changes in the behavior of the recipient. Therefore, the aim of our study was to investigate ...
    • Dietary intake of trans fatty acids and breast cancer risk in 9 European countries 

      Matta, Michèle; Huybrechts, Inge; Biessy, Carine; Casagrande, Corinne; Yammine, Sahar; Fournier, Agnès; Olsen, Karina Standahl; Lukic, Marco; Gram, Inger Torhild; Ardanaz, Eva; Sánchez, Maria-José; Dossus, Laure; Fortner, Renée T.; Srour, Bernard; Jannasch, Franziska; Schulze, Matthias B.; Amiano, Pilar; Agudo, Antonio; Colorado-Yohar, Sandra; Guirós, J. Ramón; Tumino, Rosario; Panico, Salvatore; Masala, Giovanna; Pala, Valeria; Sacerdote, Carlotta; Tjønneland, Anne; Olsen, Anja; Dahm, Christina C.; Rosendahl, Ann H.; Borgquist, Signe; Wennberg, Maria; Heath, Alicia K.; Aune, Dagfinn; Schmidt, Julie; Weiderpass, Elisabete; Chajes, Veronique; Gunter, Marc J.; Murphy, Neil (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-30)
      Background - Trans fatty acids (TFAs) have been hypothesised to influence breast cancer risk. However, relatively few prospective studies have examined this relationship, and well-powered analyses according to hormone receptor-defined molecular subtypes, menopausal status, and body size have rarely been conducted.<p> <p>Methods - In the European Prospective Investigation into Cancer and Nutrition ...
    • Transcriptome profiling of staphylococcus aureus associated extracellular vesicles reveals presence of small RNA-cargo 

      Joshi, Bishnu; Singh, Bhupender; Nadeem, Aftab; Askarian, Fatemeh; Wai, Sun Nyunt; Johannessen, Mona; Hegstad, Kristin (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-13)
      Bacterial extracellular vesicles (EVs) have a vital role in bacterial pathogenesis. However, to date, the small RNA-cargo of EVs released by the opportunistic pathogen Staphylococcus aureus has not been characterized. Here, we shed light on the association of small RNAs with EVs secreted by S. aureus MSSA476 cultured in iron-depleted bacteriologic media supplemented with a subinhibitory dosage of ...
    • Moderate-to-vigorous physical activity modifies the relationship between sedentary time and sarcopenia: the Tromsø Study 2015–2016 

      Johansson, Jonas; Morseth, Bente; Scott, David; Strand, Bjørn Heine; Hopstock, Laila Arnesdatter; Grimsgaard, Sameline (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-01)
      <p>Background: Sarcopenia is an age-related muscle disease primarily characterized by reductions in muscle strength that increases the risk of falls, fractures, cognitive impairment, and mortality. Exercise is currently preferred in prevention and treatment, but it is unknown how different habitual physical activity and sedentary behaviour patterns associate with sarcopenia status. The purpose of ...
    • Optimization of the use of PrepFiler Express™ Forensic DNA extraction kit lysis buffer discard for mRNA profiling 

      Hamnevoll, Kari (Mastergradsoppgave; Master thesis, 2021-06-01)
      mRNA profiling for body fluid or tissue type identification is able to provide circumstantial information alongside DNA profiles from biological material found at a crime scene. To solve the challenge of material limitation in body fluid identification, studies have successfully developed mRNA profiles of RNA extracted from lysis buffer discard of DNA-extraction. It would be interesting to examine ...