Self-reported health (SRH) is widely used as an epidemiological instrument given the changes in public health since its introduction in the 1980s. We examined the association between SRH and mortality and how this is affected by time and health measurements in a prospective cohort study using repeated measurements and physical examinations of 11652 men and 12684 women in Tromsø, Norway. We used Cox ...

Norwegian health authorities have a goal to reduce the total antibiotic use by 30% by 2020. Studies have shown that dentists contribute to about 8% of the total antibiotic consumption in Norway, which emphasizes the role of dentists to achieve a reduction in the use of antibiotics in the society. The antibiotic prescription pattern among Norwegian dentists from 2010 until 2016 have been mapped and ...

Angiogenesis is necessary for tumor growth and has been targeted in breast cancer; however, it is unclear which patients will respond and benefit from antiangiogenic therapy. We report noninvasive monitoring of patient response to neoadjuvant chemotherapy given alone or in combination with anti‐vascular endothelial growth factor (bevacizumab) in a randomized clinical trial. At four time points during ...

In the recent years, governmental institutions have given incentives to the pharmaceutical industry in order to develop age-appropriate dosage forms for pediatric use. This has resulted in an interest in design of new and improved dosage form for pediatric patients. One of the many recent approaches is to take advantages of ODFs. Taste masking is a crucial step in the design of not only ODFs but all ...

Background: This master’s thesis was a part of a project involving mass cultivation of microalgae at the smelting plant Finnfjord AS. Microalgae are primary producers of the important omega-3 long-chain polyunsaturated fatty acids EPA and DHA. At Finnfjord, the algae use CO2 from the flue gas for their production of lipid and protein rich biomass. The algal biomass can potentially function well as ...

Nanoparticles are usually defined as particles in a size range of 1-100 nm, and these particles often have different properties than the non-nanoscale material of the same chemical composition. In recent years, as the interest and use of nanoparticles has increased and so has the interest in understanding their behaviour, impact and fate in the environment. In the last decades, there has been special ...

The Arctic University of Norway and the ferrosilicon smeltery Finnfjord AS has started a microalgal mass cultivation project where sequestration of CO2 and NOx from factory fumes are used in the production of diatom biomass. Primary application of the produced biomass is fish feed. This requires information regarding lipid content and storage stability. In this study the lipid content, fatty acid ...

Oral squamous cell carcinoma (OSCC) is one of the frequently diagnosed type of oral cancers and is a leading cause of cancer associated mortality and morbidity worldwide. Cancer associated fibroblasts (CAFs) are activated fibroblasts that are found in association with cancer cells. CAFs are the most abundant stromal cells in the tumor microenvironment (TME). In the TME, cell interactions mediated ...

The aim was to develop a method for identification of expressed surface proteins of Staphylococcus haemolyticus when colonising human keratinocytes. S. haemolyticus and HaCaT cells were grown together and separated with FACS prior to surface protein shaving using the LPI™FlowCell technology (Nanoxis Consulting AB). TMT-tags were used to investigate up- and downregulation of proteins comparing S. ...

<i>Aims</i> - Treatment of arrhythmias evoked by hypothermia/rewarming remains challenging, and the underlying mechanisms are unclear. This <i>in vitro</i> experimental study assessed cardiac electrophysiology in isolated rabbit hearts at temperatures occurring in therapeutic and accidental hypothermia.<p><p> <i>Methods and results</i> - Detailed ECG, surface electrogram, and panoramic optical ...