Det helsevitenskapelige fakultet: Nye registreringer
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Contact with parents from childhood to adulthood – a longitudinal study of children in kinship care and non-kinship care
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-12)Previous research on parental contact for children in foster care shows that contact frequency is significantly related to parent’s gender and placement type. Yet very few studies have explored the impact of gender and type of placement on parental contact over time. Based on longitudinal quantitative data from kinship care and non-kinship care placements in Norway, we analyse contact between children ... -
Parents with a mental illness and their sense of parenting competence
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-14)Objective - Research provides evidence that parental mental illness affects child development through parenting behaviour. This study investigates how parents with a mental illness report on their parenting sense of competence.<p> <p>Method - A sample of 141 parents receiving treatment at a clinic for mental health and substance use disorders participated. The Parenting Sense of Competence scale ... -
The Self-Rated Effects of Alcohol Are Related to Presystemic Metabolism of Alcohol
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-28)Aims - A high number of alcohol units required to feel a subjective effect of alcohol predicts future alcohol use disorders (AUDs). The subjective response to alcohol can be measured using the validated retrospective self-rated effects of alcohol (SRE) questionnaire. Few studies have investigated the specific relationship between SRE and blood alcohol concentration (BAC) in an experimental ... -
Preterm birth in the Nordic countries—Capacity, management and outcome in neonatal care
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-13)Aim - Organisation of care, perinatal and neonatal management of very preterm infants in the Nordic regions were hypothesised to vary significantly. The aim of this observational study was to test this hypothesis.<p> <p>Methods - Information on preterm infants in the 21 greater healthcare regions of Denmark, Finland, Iceland, Norway and Sweden was gathered from national registers in 2021. Preterm ... -
Geographic variation in the utilisation of specialist healthcare for patients with severe mental illness in Norway: a population‑based registry study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-27)Purpose - The aim of this study is to measure geographic variations in mental healthcare service utilisation among patients with severe mental illness in Norway.<p> <p>Method - We analysed data from the Norwegian patient registry for 2014–2018 for patients with severe mental illness. The outcomes measured in this study were: outpatient contact, admission, bed days and total contact rates. Total ... -
The self-reported health of the Sámi in Sweden: the SámiHET study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-23)Background - The Sámi are an ethnic minority and the only Indigenous people in the European Union. Population-based health studies among Sámi in Sweden are scarce and outdated. The aim of this study was to analyse the ethnic, Sámi vs. non-Sámi, health differences among men and women living in Sweden.<p> <p>Methods - This study combined two data sources: the national Health on Equal Terms (HET) ... -
Machine-learning-derived heart and brain age are independently associated with cognition
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-31)Background and purpose - A heart age biomarker has been developed using deep neural networks applied to electrocardiograms. Whether this biomarker is associated with cognitive function was investigated.<p> <p>Methods - Using 12-lead electrocardiograms, heart age was estimated for a population-based sample (N = 7779, age 40–85 years, 45.3% men). Associations between heart delta age (HDA) and ... -
Introduction: Training is more important than technology (for performance in the cold)
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-27)After more than 50 years of studying soldiers in the cold, we are well past the phase of defining the unique problems; the research requirements are known but the solutions have been slow in coming. This requires iterative testing of proposed lab-based solutions with soldiers in the real environment. Representing a renewed effort to produce and implement solutions to human biomedical challenges in ... -
Education Level and Self-Reported Cardiovascular Disease in Norway—The Tromsø Study, 1994–2016
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-25)Background: Cardiovascular disease (CVD) is a leading source of morbidity and mortality, and research has shown education level to be a risk factor for the disease. The aim of this study was to investigate the association between education level and self-reported CVD in Tromsø, Norway. Methods: This prospective cohort study included 12,400 participants enrolled in the fourth and seventh surveys of ... -
Association of Systemic Medication Use with Glaucoma and Intraocular Pressure: The European Eye Epidemiology Consortium
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-06)Purpose - To investigate the association of commonly used systemic medications with glaucoma and intraocular pressure (IOP) in the European population.<p> <p>Design - Meta-analysis of 11 population-based cohort studies of the European Eye Epidemiology Consortium.<p> <p>Participants - The glaucoma analyses included 143 240 participants and the IOP analyses included 47 177 participants.<p> <p>Methods ... -
The association between macronutrients and severe musculoskeletal pain in the Tromsø7 study
(Master thesis; Mastergradsoppgave, 2023-08-01)Musculoskeletal pain is a widespread health issue that affects millions of people worldwide. It refers to any chronic or acute pain that affects muscles, ligaments, bones, and tendons. The most common types of musculoskeletal pain are low back and neck pain, with low back pain being the primary cause of disability globally. People who experience musculoskeletal pain often face negative consequences, ... -
Economic Evaluation of Home-Based Stroke Care – A systematic review
(Master thesis; Mastergradsoppgave, 2023-08-01)Background: The Global Burden of Disease (GBD) of 2019 ranked stroke, as both the second-leading cause of death and the third-leading cause of death and disability worldwide. As the burden of stroke has risen the past three decades, stroke has emerged as one of the current greatest public health issues worldwide of growing importance. During the past 40 years, healthcare expenditure has increased ... -
Improving validity of the trail making test with alphabet support
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-27)The Trail Making Test (TMT) is commonly used worldwide to evaluate cognitive decline and car driving ability. However, it has received critique for its dependence on the Latin alphabet and thus, the risk of misclassifying some participants. Alphabet support potentially increases test validity by avoiding misclassification of executive dysfunction in participants with dyslexia and those with insufficient ... -
Social identity threat is related to ethnic minority adolescents’ social approach motivation towards classmates via reduced sense of belonging
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-13)The integration of ethnic minority youth can only be successful if they are motivated to establish and maintain social relationships in important institutions such as school. At the same time, worries about negative stereotypes about one’s ethnic group can undermine ethnic minority students’ motivation to approach others. In the present study, we tested whether social identity threat predicts ethnic ... -
On the Therapeutic Potential of ERK4 in Triple-Negative Breast Cancer
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-21)ERK3 and ERK4 define a distinct and understudied subfamily of mitogen-activated protein kinases (MAPKs). Little is known about the physiological roles of these atypical MAPKs and their association with human diseases. Interestingly, accumulating evidence points towards a role for ERK3 and ERK4 signaling in the initiation and progression of various types of cancer. Notably, a recent study reported ... -
On indications for cancer immunotherapy: A review of current practice for immunology-based indications
(Master thesis; Mastergradsoppgave, 2021-08-23)Knowledge of tumor immunology and immune escape mechanisms was the basis for developing immune checkpoint inhibitors (ICI) for cancer therapy. These target and block checkpoint molecules commonly implicated in tumor immune escape by overexpression, such as PD-1, its ligand, PD-L1 or CTLA-4. Use of ICIs has been approved mostly for treatment of advanced disease, some without any requirement ... -
Kartlegging av posttraumatisk stress hos ambulansepersonell ved Universitetssykehuset Nord-Norge HF
(Master thesis; Mastergradsoppgave, 2021-08-23)Bakgrunn og formål Internasjonalt er det dokumentert at ambulansepersonell har økt risiko for å utvikle posttraumatisk stressyndrom (PTSD), men det er foreløpig gjort lite forskning på norsk ambulansepersonell. Formålet med oppgaven var å kartlegge forekomst og fordeling av potensielt traumatiserende hendelser (PTE), symptomer på posttraumatisk stress, angst, depresjon og alkoholbruk hos ... -
Mortality after hospital admission for trauma in Norway: A retrospective observational national cohort study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-28)Background - National quality data for trauma care in Norway have not previously been reported. We have therefore assessed crude and risk-adjusted 30-day mortality in trauma cases after primary hospital admission on national and regional levels for 36 acute care hospitals and four regional trauma centres.<p> <p>Methods - All patients in the Norwegian Trauma Registry in 2015–2018 were included. ... -
Opioid prescriptions among Sami and non-Sami with chronic pain: The SAMINOR 2 Questionnaire Survey and the Norwegian Prescription Database
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-28)This study is the first to investigate the prevalence of filled opioid prescriptions among indigenous Sami people with self-reported chronic musculoskeletal pain (CMSP) and compare it with that of non-Sami living in the same area. Baseline data from the SAMINOR 2 Questionnaire Survey (2012) was linked prospectively to the Norwegian Prescription Database. Information on filled opioid prescriptions ... -
A Qualitative Study Among Healthcare Providers on Risks Associated With the Use of Supportive Care for Cancer Treatment-Related Symptoms in Children and Adolescents
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-08-18)Introduction: Although more than 300 000 children and adolescents worldwide are diagnosed with cancer yearly, little research has been conducted investigating how healthcare providers consider risk and patient safety connected with supportive care (including complementary and alternative medicine [CAM]) in this age group. This study aimed to explore how different healthcare providers perceive and ...