Det helsevitenskapelige fakultet: Nye registreringer
Viser treff 1681-1700 av 10407
-
Towards interprofessional patient care: Health profession students exploring interprofessional collaboration in group meetings in joint clinical placement
(Doctoral thesis; Doktorgradsavhandling, 2023-01-20)The aim of this study is to develop knowledge about how health profession students learn interprofessional collaboration in group meetings during a joint voluntary period of practice. It is an observational study. Interprofessional student groups were followed throughout a two-week practice period. The groups had a mandate to independently develop interprofessional collaboration in the healthcare ... -
The seventh survey of the Tromsø Study (Tromsø7) 2015–2016: study design, data collection, attendance, and prevalence of risk factors and disease in a multipurpose population-based health survey
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-04)Aims: The Tromsø Study is an ongoing population-based health study in Tromsø, Norway, initiated in 1974. The purpose of the seventh survey (Tromsø7) 2015–2016 was to advance the population risk factor surveillance and to collect new types of data. We present the study design, data collection, attendance, and prevalence of risk factors and disease. Methods: All inhabitants in Tromsø municipality, ... -
Strategies to inhibit FGFR4 V550L-driven rhabdomyosarcoma
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-12)Background: Rhabdomyosarcoma (RMS) is a paediatric cancer driven either by fusion proteins (e.g., PAX3-FOXO1) or by mutations in key signalling molecules (e.g., RAS or FGFR4). Despite the latter providing opportunities for precision medicine approaches in RMS, there are currently no such treatments implemented in the clinic.<p> <p>Methods: We evaluated biologic properties and targeting strategies ... -
A study of occupational health among mine workers in Murmansk Oblast, Russia
(Doctoral thesis; Doktorgradsavhandling, 2014-05-27)The mining industry is growing in the north, with the largest mining communities located in North Russia. Increased knowledge about the health and work conditions of the employees is important in order to enhance safety and prevention of ill health. The aim of the study was to describe how the health of mine workers in Murmansk oblast is assessed, determine the prevalence of low back pain (LBP) as ... -
Hjertepasienters opplevelse av fysisk aktivitet og trening: En kvalitativ metasyntese
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-27)Bakgrunn: Treningsbasert hjerterehabilitering kan øke livskvalitet, bedre arbeidskapasitet og redusere risikofaktorer for reinnleggelse og kardiovaskulær død. Likevel klarer mange pasienter ikke fortsette med trening etter et rehabiliteringsopphold, og kun halvparten klarer å opprettholde det anbefalte nivået for fysisk aktivitet. Derfor er det viktig å undersøke hvilke erfaringer pasientene har med ... -
SLE classification criteria: Science-based icons or algorithmic distractions – an intellectually demanding dilemma
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-28)It is, so to say, not a prerogative authority assigned to SLE classification criteria that allow them to declare something definitively important about SLE. This is particularly true as criteria-based classification processes overrule the highly needed evolution of concise diagnostic criteria. It is classification criteria that allocate SLE patients into cohorts intended to describe the nature of ... -
Discovering the structure and organization of a free Cantonese emotion-label word association graph to understand mental lexicons of emotions
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-15)Emotions are not necessarily universal across different languages and cultures. Mental lexicons of emotions depend strongly on contextual factors, such as language and culture. The Chinese language has unique linguistic properties that are different from other languages. As a main variant of Chinese, Cantonese has some emotional expressions that are only used by Cantonese speakers. Previous work on ... -
Comparative analysis of Vibrio cholerae isolates from Ghana reveals variations in genome architecture and adaptation of outbreak and environmental strains
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-13)Recurrent epidemics of cholera denote robust adaptive mechanisms of Vibrio cholerae for ecological shifting and persistence despite variable stress conditions. Tracking the evolution of pathobiological traits requires comparative genomic studies of isolates from endemic areas. Here, we investigated the genetic differentiation among V. cholerae clinical and environmental isolates by highlighting the ... -
The Composition and Functional Capacities of Saliva Microbiota Differ Between Children With Low and High Sweet Treat Consumption
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-25)Excess sugar consumption—common in youth—is associated with poor health. Evidence on the relationship between sugar consumption and the oral microbiome, however, remains scarce and inconclusive. We explored whether the diversity, composition, and functional capacities of saliva microbiota differ based on the consumption of select sugary foods and drinks (“sweet treats”). Using 16S rRNA gene sequencing, ... -
Adherence to mediterranean diet and the risk of differentiated thyroid cancer in a European cohort: The EPIC study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-02)Background: The Mediterranean diet (MD) has been proposed as a healthy diet with a potential to lower the incidence of several types of cancer, but there is no data regarding thyroid cancer (TC). We investigated the association between MD adherence, and its components, and the differentiated TC risk within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.<p> <p>Methods: ... -
Systematic review and meta-analysis of Chinese herbal formula Tongxie Yaofang for diarrhea-predominant irritable bowel syndrome: Evidence for clinical practice and future trials
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-25)Introduction: Diarrhea-predominant irritable bowel syndrome (IBS-D) significantly decreases the quality of life of patients and their families, and affects patients’ mental health. No specific western medications are available. Ancient classical Chinese medical texts have recognized Tongxie Yaofang (TXYF) as a therapy for diarrhea which is widely used in clinical practice. Standard TXYF prescription ... -
Attention-deficit/hyperactivity disorder symptoms, perceived stress, and suicidal ideation during the COVID-19 pandemic
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-09)Objective: Attention–deficit/hyperactivity disorder (ADHD) symptoms have been linked to suicidal behavior. However, little is known about the mechanisms involved in this association. This study examined ADHD symptoms and suicidal ideation during the COVID-19 pandemic and the role of self–perceived stress in this association.<p> <p>Method: Data were analyzed from an online sample of 1,452 Japanese ... -
Communication about medication management during patient-physician consultations in primary care: a participant observation study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-03)Objective - To explore communication about medication management during annual consultations in primary care. Design: passive participant observations of primary care consultations.<p> <p>Setting - Two primary care centres in southern Sweden.<p> <p>Participants - Consultations between 18 patients (over the age of 60 years) with chronic diseases and 10 general practitioners (GPs) were observed, ... -
Prediction of long-term remission in patients following discontinuation of anti-TNF therapy in ulcerative colitis: a 10 year follow up study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-16)Background - The long-term outcomes of Ulcerative colitis (UC) after discontinuation of biological therapy are largely unknown. There is also a lack of accurate and validated markers that can predict outcome after withdrawal accurately. The aims of this study were to describe the long-term outcomes in UC patients following cessation of anti-TNF therapy and explore potential biomarkers as an approach ... -
Pharmacodynamic mechanisms behind a refractory state in inflammatory bowel disease
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-17)Background and aims - Biological therapy for inflammatory bowel disease is efficient in many cases but not all. The underlying molecular mechanisms behind non-response to biological therapy in inflammatory bowel disease are poorly described. Therefore, we aimed to characterize the mucosal cytokine transcript profile in non-immunogenic, non-responder patients with adequate trough level.<p> <p>Material ... -
Outcomes and predictors of functioning, mental health, and health-related quality of life in adults born with very low birth weight: a prospective longitudinal cohort study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-03)Background - Very low birth weight (VLBW: ≤1500 g) is associated with multiple short and long-term complications. This study aimed to examine outcomes and predictors of functioning, mental health, and health-related quality of life in adults born with VLBW.<p> <p>Methods - In this prospective longitudinal cohort study, 67 VLBW and 102 control participants were assessed using the Adult Self-Report ... -
Challenges and opportunities for general practice specific CME in Europe – a narrative review of seven countries
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-07)Background - Several changes have led to general practitioners (GPs) working in a more differentiated setting today and being supported by other health professions. As practice changes, primary care specific continuing medical education (CME) may also need to adapt. By comparing different primary care specific CME approaches for GPs across Europe, we aim at identifying challenges and opportunities ... -
Polish immigrants’ access to colorectal cancer screening in Norway – a qualitative study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-10)Background - The Norwegian colorectal cancer (CRC) screening programme started in May 2022. Inequities in uptake of CRC screening is a concern, and we expect that immigrants are at risk of non-uptake. Immigrants from Poland are the most populous immigrant group in Norway. The purpose of this study was to identify and explore factors that may facilitate Polish immigrants’ access to the Norwegian CRC ... -
Pan-cancer analysis of pre-diagnostic blood metabolite concentrations in the European Prospective Investigation into Cancer and Nutrition
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-19)Background - Epidemiological studies of associations between metabolites and cancer risk have typically focused on specific cancer types separately. Here, we designed a multivariate pan-cancer analysis to identify metabolites potentially associated with multiple cancer types, while also allowing the investigation of cancer type-specific associations.<p> <p>Methods - We analysed targeted metabolomics ... -
“They make a diference”: a qualitative study of providers’ experiences of peer support in outpatient clinics for people living with HIV
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-21)Background Although the life expectancy of people living with HIV has increased, they are still often disconnected from society through stigma and discrimination. Peer support has been found to increase social support. Given the limited research on peer support from the providers’ perspective, this study explored how peer supporters experience their roles and contributions in outpatient clinics ...