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norskDet helsevitenskapelige fakultet: Nye registreringer
Viser treff 2001-2020 av 10407
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Utprøvende behandling ved helseplager attribuert til amalgamfyllinger. En prospektiv kohortstudie
(Research report; Forskningsrapport, 2022-06)På oppdrag fra Helsedirektoratet har Bivirkningsgruppen for odontologiske biomaterialer gjennomført et prosjekt med utprøvende behandling rettet mot pasienter med langvarige medisinsk uforklarte helseplager (MUPS) som de selv mente hadde sammenheng med amalgamfyllinger. Pasientene ble på forhånd undersøkt av tannlege og lege i henhold til gjeldende retningslinjer og fikk deretter skiftet ut alle ... -
Epithelial ovarian cancer. Population-based cohort studies. The NOWAC Study and Postgenome biobank
(Doctoral thesis; Doktorgradsavhandling, 2022-10-19)Important gaps in population-based epidemiological research on ovarian cancer include understanding how risk factors relate to cancer subtypes and anatomical sites, identifying safe and effective preventive measures, and getting a more detailed picture of the continuum of events during ovarian carcinogenesis. This thesis used prospective exposure information from the Norwegian Women and Cancer (NOWAC) ... -
Explaining reduction of pedestrian-motor vehicle crashes in Arkhangelsk, Russia, in 2005-2010
(Journal article; Tidsskriftartikkel; Peer reviewed, 2012-09-24)Objective. To explain a reduction in pedestrianmotor vehicle crashes in Arkhangelsk, Russia, in 20052010.<p> <p>Study design. Retrospective ecological study. <p>Methods. For 20052010, police data on pedestrianmotor vehicle crashes, traffic violations, and total motor vehicles (MVs) were combined with data on changes in national road traffic legislation and municipal road infrastructure. Negative ... -
Traditional Chinese Medicine in Cancer Care: A Review of Case Series Published in the Chinese Literature
(Journal article; Tidsskriftartikkel; Peer reviewed, 2012-05-31)Traditional Chinese medicine (TCM) has been widely used in cancer in China. Case series report a series of cases exposed to a certain intervention. To understand the current situation of case series of TCM for cancer, we performed this review. We included case series of cancer patients treated with TCM therapy. Electronic searches were conducted in four main Chinese databases until February 2011. ... -
The ecology of medical care in Norway: wide use of general practitioners may not necessarily keep patients out of hospitals
(Journal article; Tidsskriftartikkel; Peer reviewed, 2012)Background. Our aim was to investigate the pattern of self reported symptoms and utilisation of health care services in Norway.<p> <p>Design and Methods. With data from the cross-sectional Tromsø Study (2007-8), we estimated population proportions reporting symptoms and use of seven different health services. By logistic regression we estimated differences according to age and gender. <p>Results. ... -
Turnover of IPS employment specialists: Rates and predictors
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-15)BACKGROUND: There are anecdotal reports of high job turnover of Individual Placement and Support employment specialists. However, no studies have addressed this issue.<p> <p>OBJECTIVE: To explore whether turnover rates among employment specialists are higher compared to public sector employees along with the correlates of turnover intentions. <p>METHODS: A repeated cross-sectional study collected ... -
From the conventional to the alternative: Exploring patients' pathways of cancer treatment and care
(Journal article; Tidsskriftartikkel; Peer reviewed, 2015-08-08)Background: Complementary and alternative medicine (CAM) use is widespread and on the increase among cancer patients. Most research to date has involved a cross-sectional snapshot of CAM use rather than an exploration into the longitudinal, nonlinear treatment trajectories that cancer patients develop. Our aim is to explore and describe different treatment and decision-making pathways that individuals ... -
Behavior of E. coli ST131 regarding the acquisition of a blaOXA-48 encoding plasmid
(Master thesis; Mastergradsoppgave, 2021-05-11)Antimicrobial resistance has been a challenge ever since the discovery of antibiotics. The rising challenge of resistance has led to the increased use of last-resort antibiotics: carbapenems. It is predicted that a successful E. coli clone, ST131 is apt for the acquisition of carbapenem-resistance encoding plasmids. In this study, we aim to understand how E. coli ST131 respond to acquisition of ... -
Mercaptoalkanol-derived self-immolative linkers for bioconjugates. Synthesis and analysis
(Master thesis; Mastergradsoppgave, 2021-01-11)Many of the anticancer compounds discovered through synthesis or bioprospecting activities are found to be equally toxic to healthy cells and tumors. Consequently, these compounds are not considered as promising drug candidates worthy of further study. This project seeks to develop a novel chemical toolkit that can be utilized to increase the therapeutic value of such toxic compounds by decreasing ... -
Molecular Modelling of PDE3A Catalytic Domain
(Master thesis; Mastergradsoppgave, 2020-05-14)<p>Recent studies have highlighted the clinical benefits of regulating phosphodiesterase-3 enzymes. Inhibition of PDE3A has proven to aid in preventing and treating cardiovascularrelated disorders and platelet dysfunction. Hypothermia is a condition that can cause cardiac arrest. However, there are no suitable inotropic drugs that are effective for use under hypothermic conditions. Being able to ... -
Interpersonal competence in challenging encounters: Towards a paradigm shift in human services - Creating conditions for professional development through action research and trauma-informed restorative practice
(Doctoral thesis; Doktorgradsavhandling, 2022-10-04)Helse- og sosialarbeidere, i private og offentlige arbeids- og velferdstjenester, har daglig kontakt med mennesker som har traumeerfaringer og sammensatte behov. Kommunikasjonen kan være følelsesmessig utfordrende og mange fagpersoner opplever dårlig tid, utrygghet og stress i arbeidet. Utrygghet og stress øker konfliktnivået og har en negativ effekt på fagpersoners velvære, holdninger til tjenestebrukere ... -
Infant sleep as a topic in healthcare guidance of parents, prenatally and the frst 6months after birth: a scoping review
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-08)Svalbard is a remote and scarcely populated Arctic archipelago and is considered to be mostly influenced by long-range-transported air pollution. However, there are also local emission sources such as coal and diesel power plants, snowmobiles and ships, but their influence on the background concentrations of trace gases has not been thoroughly assessed. This study is based on data of tropospheric ... -
Biofilm-related characteristics in clinical isolates of Extraintestinal Pathogenic E. coli
(Mastergradsoppgave; Master thesis, 2021-05-10)The rapid increase in antibiotic resistance is one of the leading global health issues at present time. Bacteria’s resistance to antibiotic agents can be a thousand times higher when they are embedded in an extracellular biopolymer matrix, defined as biofilm. The biofilm state is a major driver of persistent infections, offering a challenge in providing adequate treatment. Biofilm producing E. coli ... -
Misinformation about Covid-19 Vaccines on Social Media: Rapid Review
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-04)Background: The development of COVID-19 vaccines has been crucial in fighting the pandemic. However, misinformation about the COVID-19 pandemic and vaccines is spread on social media platforms at a rate that has made the World Health Organization coin the phrase infodemic. False claims about adverse vaccine side effects, such as vaccines being the cause of autism, were already considered a threat ... -
A Novel Porcine Model of Ischemia-Reperfusion Injury After Cross-Clamping the Thoracic Aorta Revealed Substantial Cardiopulmonary, Thromboinflammatory and Biochemical Changes Without Effect of C1-Inhibitor Treatment
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-01)Ischemic injury worsens upon return of blood and innate immunity including the complement system play a central role in ischemia-reperfusion injury (IRI) as in thoracic aortic surgery. Complement component1 inhibitor (C1-INH) has been shown to reduce IRI and is a broad-acting plasma cascade inhibitor. We established a new porcine model of IRI by cross-clamping the thoracic aorta and evaluated the ... -
Physiological Changes in Subjects Exposed to Accidental Hypothermia: An Update
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-23)Background: Accidental hypothermia (AH) is an unintended decrease in body core temperature (BCT) to below 35°C. We present an update on physiological/pathophysiological changes associated with AH and rewarming from hypothermic cardiac arrest (HCA).<p> <p>Temperature Regulation and Metabolism: Triggered by falling skin temperature, Thyrotropin-Releasing Hormone (TRH) from hypothalamus induces ... -
Benefit and risk assessment of fish in the Norwegian diet - Scientific Opinion of the Steering Committee of the Norwegian Scientific Committee for Food and Environment
(Research report; Forskningsrapport, 2022-06-07)In 2006, VKM published “A comprehensive assessment of fish and other seafood in the Norwegian diet”. The assessment supported the recommendation from Norwegian Health authorities to eat more fish both for dinner and on sandwiches. In an update of the assessment in 2014 VKM concluded that “the benefits from fish consumption clearly outweigh the negligible risk presented by current levels of ... -
The role of early adversity and cognitive vulnerability in postnatal stress and depression
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-12)The purpose of the present study was to examine vulnerability factors in expecting parents that might lead to mental illness in the perinatal period. Specifcally, we studied how parental early adversity, attentional bias to infant faces, repetitive negative thinking, and demographic factors, were associated with pre- and postnatal depressive symptoms and parenting stress. Participants were expecting ... -
Large-Scale EHR Suites and Path-Dependence
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-29)Large-scale electronic health record (EHR) suites are expected to cover a broad range of use scenarios for healthcare workers in hospitals, nursing homes, home-care services, and general practitioner (GP) clinics. However, preparation for the implementation of EHR suites requires years of detailed planning and consumes considerable financial and human resources. A key problem, then, is that there ... -
Individuell og kollektiv sårbarhet i hjelperrollen
(Chapter; Bokkapittel, 2021)Veiledere innen helse- og sosialfaglige velferdstjenester er i daglig kontakt med mennesker som har opplevd traumer og har utfordringer på mange livsområder: arbeid, bolig, økonomi, og sosialt: psykiske og fysiske helseutfordringer. Å stå i disse møtene krever mellommenneskelig kompetanse og trygghet. Forskning indikerer at mange fagprofesjoner opplever at de ikke har tid til å bygge relasjoner, og ...
