Viser treff 941-960 av 10398

    • Independent Validation of a Unifying Prognostic Model for Intracranial and Extracranial Metastasis-directed Radiotherapy 

      Nieder, Carsten; Stanisavljevic, Luka; Mannsåker, Bård; Haukland, Ellinor Christin (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-06)
      We present the first calculations of the heavy flavor diffusion coefficient using lattice QCD with light dynamical quarks corresponding to a pion mass of around 320 MeV. For temperatures 195 MeV <T< 352 MeV, the heavy quark spatial diffusion coefficient is found to be significantly smaller than previous quenched lattice QCD and recent phenomenological estimates. The result implies very fast ...
    • Characteristics and outcomes of patients who did not respond to a national spine surgery registry 

      Kaur, Simran; Alhaug, Ole Kristian; Dolatowski, Filip Celestyn; Solberg, Tore; Lønne, Greger (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-04)
      Background Loss to follow-up may bias outcome assessments in medical registries. This cohort study aimed to analyze and compare patients who failed to respond with those that responded to the Norwegian Registry for Spine Surgery (NORspine).<p> <p>Methods We analyzed a cohort of 474 consecutive patients operated for lumbar spinal stenosis at four public hospitals in Norway during a two-year period. ...
    • Nord og ned? 

      Agledahl, Kari Milch; Wisborg, Torben (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-29)
      I sykehustalen for 2023 ba helseministeren Helse Nord om å sikre «bærekraften» fordi den økonomiske situasjonen er prekær. Dette brukes nå for å legitimere strukturelle endringer som vil endre helsetjenesten i nord dramatisk.
    • AlphaFold-multimer predicts ATG8 protein binding motifs crucial for autophagy research 

      Olsvik, Hallvard Lauritz; Johansen, Terje (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-08)
      Proteins are structural and executing macromolecules essential for life in all biological systems. Insight into proteins structures is required for detailed mechanistic understanding of how they work and solve different tasks. The ability to predict three-dimensional (3D) protein structures from primary sequence information has therefore been an open research question for more than 50 years. The ...
    • Cohort profile: The Clinical and Multi-omic (CAMO) cohort, part of the Norwegian Women and Cancer (NOWAC) study 

      Delgado, André Berli; Tylden, Eline Sol Garthsdatter; Lukic, Marko; Moi, Line Haugan; Rasmussen Busund, Lill-Tove; Lund, Eiliv; Olsen, Karina Standahl (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-06)
      Introduction - Breast cancer is the most common cancer worldwide and the leading cause of cancer related deaths among women. The high incidence and mortality of breast cancer calls for improved prevention, diagnostics, and treatment, including identification of new prognostic and predictive biomarkers for use in precision medicine.<p> <p>Material and methods - With the aim of compiling a cohort ...
    • En trøstende kontakt mellom sykepleier og pasient 

      Glad, Tone (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-30)
      Hensikten med dette essay er å belyse hva trøst i sykepleien kan være og hvordan kontakt mellom pasient og sykepleier kan oppleves trøstende for pasienter. Bakgrunnen for essayet er en pasients brev til sykepleier om det å ha noen å snakke med under behandlingsoppholdet i sykehuset. I samtalen med pasienten kan sykepleier oppnå kontakt, også kontakt med sin egen karakter og grenser. Når vi tror ...
    • C-reactive protein levels and depression in older and younger adults - A study of 19,947 individuals. The Tromsø study 

      Bugge, Erlend; Wynn, Rolf; Mollnes, Tom Eirik; Reitan, Solveig Merete Klæbo; Lapid, Maria I.; Grønli, Ole Kristian (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-17)
      In recent years, a connection between depression and inflammation has been established, with a range of immunological changes, both cellular and humoral, presenting during depressive states (Beydoun et al., 2016; Haapakoski et al., 2015; Wium-Andersen et al., 2013). Furthermore, there seems to be a dose-response relationship between depression and inflammation, in the sense that the more severe the ...
    • 13-Type HPV DNA Test versus 5-Type HPV mRNA Test in Triage of Women Aged 25–33 Years with Minor Cytological Abnormalities–6 Years of Follow-Up 

      Rad, Amir; Sørbye, Sveinung; Brenn, Tormod; Tiwari, Sweta; Løchen, Maja-Lisa; Skjeldestad, Finn Egil (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-25)
      Background: A specific, cost-effective triage test for minor cytological abnormalities is essential for cervical cancer screening among younger women to reduce overmanagement and unnecessary healthcare utilization. We compared the triage performance of one 13-type human papillomavirus (HPV) DNA test and one 5-type HPV mRNA test. Methods: We included 4115 women aged 25–33 years with a screening ...
    • Bruk av glukokortikoider i oral medisin 

      Aaøyen, Øyvind; Johansen, Hanna P.; Dragland, Lars Roger (Master thesis; Mastergradsoppgave, 2023-05-02)
      Denne masteroppgaven tar for seg konsensus i bruk av glukokortikoider blant norske spesialister, retningslinjer og hva som finnes i litteraturen. Videre ønsker vi å sammenligne behandling av oraleslimhinne lidelser med glukokortikoider og ikke-steroidholdige alternativer. Metoden som ble brukt i denne undersøkelsen var en spørreundersøkelse sendt til spesialistene i Norge som oftest har konsultasjoner ...
    • Dental implant treatment in irradiated oral cancer patients. Clinical routines in Norway and a review of the literature 

      Jensen, Amalie Storaa; Hestnes, Ida Johansen (Master thesis; Mastergradsoppgave, 2023-04-28)
      The study seeks to find out if there is a difference in prognosis of primary and secondary dental implantation, i.e. before or after radiotherapy respectively, in cancer patients. We carried out a literature search, as well as investigating if there were different practices at the various hospitals in Norway who perform such treatment.
    • Lipid Levels During Adult Lifetime in Men and Women With and Without a Subsequent Incident Myocardial Infarction: A Longitudinal Analysis of Data From the Tromsø Study 1974 to 2016 

      Albrektsen, Grethe; Wilsgaard, Tom; Heuch, Ivar; Løchen, Maja-Lisa; Thelle, Dag Steinar; Njølstad, Inger; Grimsgaard, Sameline; Bønaa, Kaare Harald (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-14)
      Background - The atherosclerotic effect of an adverse lipid profile is assumed to accumulate throughout life, leading to increased risk of myocardial infarction (MI). Still, little is known about age at onset and duration of unfavorable lipid levels before MI.<p> <p>Methods and Results - Longitudinal data on serum lipid levels for 26 130 individuals (50.5% women, aged 20–89 years) were obtained ...
    • Percent of remaining life on palliative radiation treatment: solely a function of fractionation? 

      Nieder, Carsten; Mannsåker, Bård; Dalhaug, Astrid (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-14)
      Background: This study analyzed the percent of remaining life (PRL) on treatment in patients irradiated for bone metastases. Bone metastases were treated together with other target volumes, if indicated, e.g. a 10-fraction treatment course that included brain and bone metastases. PRL was determined by calculating the time between start and finish of palliative radiotherapy (minimum 1 day in case of ...
    • Evaluation of Synthetic Categorical Data Generation Techniques for Predicting Cardiovascular Diseases and Post-Hoc Interpretability of the Risk Factors 

      García-Vicente, Clara; Chushig-Muzo, David; Mora-Jiménez, Inmaculada; Fabelo, Himar; Gram, Inger Torhild; Løchen, Maja-Lisa; Granja, Conceição; Soguero-Ruiz, Cristina (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-23)
      Machine Learning (ML) methods have become important for enhancing the performance of decision-support predictive models. However, class imbalance is one of the main challenges for developing ML models, because it may bias the learning process and the model generalization ability. In this paper, we consider oversampling methods for generating synthetic categorical clinical data aiming to improve the ...
    • Inflammatory Biomarkers Can Differentiate Acute Lymphoblastic Leukemia with Arthropathy from Juvenile Idiopathic Arthritis Better Than Standard Blood Tests 

      Brix, Ninna; Glerup, Mia; Foell, Dirk; Kessel, Christoph; Wittkowski, Helmut; Berntson, Lillemor; Fasth, Anders; Nielsen, Susan; Nordal, Ellen Berit; Rygg, Marite; Hasle, Henrik; Herlin, Troels (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-04-04)
      Objective - To evaluate the predictive value of biomarkers of inflammation like phagocyte-related S100 proteins and a panel of inflammatory cytokines in order to differentiate the child with acute lymphoblastic leukemia (ALL) from juvenile idiopathic arthritis (JIA).<p> <p>Study design - In this cross-sectional study, we measured S100A9, S100A12, and 14 cytokines in serum from children with ALL ...
    • Complementary and alternative medicine use for supportive care in childhood cancer - Prevalence of use, effectiveness, safety and clinical practice 

      Mora, Dana Catalina (Doctoral thesis; Doktorgradsavhandling, 2023-10-03)
      <p>Childhood cancer treatment protocols have been successful due to the prompt and accurate diagnosis, availability of care, and access to high-quality medical resources. As the survival rates increase in high-income countries (HIC), the emphasis has shifted from survival to survival, emphasizing quality of life. The health complaints and adverse effects of cancer treatment are burdensome for children, ...
    • Neurological and respiratory effects of lung protective ventilation in acute brain injury patients without lung injury: brain vent, a single centre randomized interventional study 

      Beqiri, Erta; Smielewski, Peter; Guérin, Claude; Czosnyka, Marek; Robba, Chiara; Bjertnæs, Lars Jakob; K Frisvold, Shirin (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-20)
      Introduction - Lung protective ventilation (LPV) comprising low tidal volume (VT) and high positive end-expiratory pressure (PEEP) may compromise cerebral perfusion in acute brain injury (ABI). In patients with ABI, we investigated whether LPV is associated with increased intracranial pressure (ICP) and/or deranged cerebral autoregulation (CA), brain compensatory reserve and oxygenation.<p> <p>Methods ...
    • Cohesive collisions of particles in liquid media studied by CFD-DEM, video tracking, and Positron Emission Particle Tracking 

      Saparbayeva, Nazerke; Chang, Yu-Fen; Kosinski, Pawel Jan; hoffmann, alex christian; Balakin, Boris; Struchalin, Pavel (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-18)
      This paper investigates the cohesive collision of ice in an oil phase at temperatures ranging from −15.7 °C to −0.3 °C. The new information on the coefficient of restitution (COR) was obtained using three different velocity measurement methods: high-speed experimental video recording, Positron Emission Particle Tracking (PEPT), and numerical simulations. A new type of PEPT tracer was developed for ...
    • Mental health profiles among 13-16-year-Old Norwegian talent and mainstream students - A prospective person-centered analytical approach 

      Stornæs, Annett Victoria; Sundgot-Borgen, Jorunn; Pettersen, Gunn; Rosenvinge, Jan H; Nordin-Bates, Sanna M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-07)
      Objectives: To contribute further knowledge about symptoms of anxiety, depression, body concerns, and self-worth among young talent development (TD) and mainstream students by exploring the indicators within-person combinations prospectively, aiming to identify distinct profiles. Methods: We included 946 students, n = 168 (45% girls) from three TD sports schools and one ballet class, n = 778 ...
    • Amplified disparities: The association between spousal education and own health 

      Lamu, Admassu Nadew; Chen, Gang; Olsen, Jan Abel (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-11)
      Positive associations between own educational attainment and own health have been extensively documented. Studies have also shown spousal educational attainment to be associated with own health. This paper investigates the extent to which spousal education contributes to the social gradient in health, net of own education; and whether parts of a seeming spousal education effect are attributable to ...
    • Pre-diagnostic intake of vitamin D and incidence of colorectal cancer by anatomical subsites: the Norwegian Women and Cancer Cohort Study (NOWAC) 

      Paulsen, Elise Marlen; Rylander, Karin Charlotta Maria; Brustad, Magritt; Jensen, Torill Miriam Enget (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-09)
      According to the World Cancer Research Fund International, vitamin D might decrease the risk of colorectal cancer (CRC). However, less is known about the association with cancers in different subsites of the colon and in the rectum. The aim of this study was to examine associations between pre-diagnostic intake of vitamin D and risk of CRC by anatomical subsites. Data from 95 416 participants in the ...