The need for recruiting and retaining general practitioners (GPs) is expected to increase substantially in the next years, both because of an ageing population and a reform suggesting to shift more resources to primary care. This will not only reinforce the current challenge of recruitment and retention in rural areas, but it may also make it more difficult to recruit and retain GPs in urban areas. ...

The genetically modified maize event MON810 has been inserted with a processed version of the transgene, cry1ab, derived from the soil bacterium Bacillus thuringiensis (Bt) to express proteins with insecticidal properties. The introduced toxin may confer risks of immunogenicity, allergenicity and/or adjuvanticity to humans as well as domestic and wild animals, via inhalation of pollen and plant ...

Treatment of vaginal infections remains unsuccessful due to recurrent infections and limited patient compliance. Current therapies are unable to penetrate bacterial and fungal biofilms, allowing the survival of microorganisms, which often leads to new infections. Local administration of drug is able to provide a higher drug concentration at the vaginal site; enabling the administration of lower drug ...

Constraint-induced movement therapy (CIMT) is a treatment for mild-to-moderate upper extremity motor dysfunction in post-stroke patients. However, as the ideal time to initiate post-stroke treatment remains uncertain, more information is needed regarding the effects of CIMT and arm use in the early stages of stroke recovery. This thesis aimed to: 1) examine the correlations between arm motor ...

Background: Radiotherapy causes oral mucositis (OM) that is painful and disrupts eating, talking, social activities and general health. OM may even interrupt cancer therapy. Any intervention that can reduce OM will lead to improvement in treatment and quality of life for patients. It is essential to have a suitable tool to measure potentially effective and new treatments against OM. Objective: To ...

Summary Obesity is considered a worldwide pandemic. Morbidly obese patients are at risk of developing comorbidity such as diabetes mellitus type 2, hypertension and cardiovascular disease. The mechanisms behind the development of such complications in morbidly obese patients are still not fully understood, but low-grade inflammation and visceral adiposity are both involved. Effective treatment that ...

Denne studien har undersøkt Escherichia coli resistente for kinoloner, en bredpektret gruppe antibiotika. Målet har vært å finne ut hvorfor disse bakteriene oftere er resistente mot andre antoibiotikagrupper. Studiet er basert på molekylærgenetisk analyser - herunder klonal analyse, plasmidanalyser og undersøkelse av resistensgener. Resultatene viser at kinolonresistente Escherichia coli er ofte ...

Although several routes of administration can be utilized to bring a drug to the desired site of action, oral administration is still the most important and prevalent route of administration, due to its cost efficiency, convenience and patient compliance. A prerequisite for successful oral therapy is the ability of a drug to cross the gastrointestinal barrier. Over the past two decades, the ...

Prescriptions of antibiotics in Norway, and the effect of antibiotics on bacteria were investigated. The aim was to describe the consumption of antibiotics through prescriptions to patients and address how antibiotics can favour bacterial resistance. Several methods were applied, multivariate statistics, quantile regression and mathematical modelling of experimental conditions aided in the investigations. ...