Viser treff 261-280 av 2796

    • Systemic inflammation early after kidney transplantation is associated with long-term graft loss: a cohort study 

      Heldal, Torbjørn Fossum; Åsberg, Anders; Ueland, Thor; Reisæter, Anna Varberg; Pischke, Soeren; Mollnes, Tom Eirik; Aukrust, Pål; Reinholt, Finn P.; Hartmann, Anders; Heldal, Kristian; Jenssen, Trond (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-02)
      Background: Early graft loss following kidney transplantation is mainly a result of acute rejection or surgical complications, while long-term kidney allograft loss is more complex. We examined the association between systemic inflammation early after kidney transplantation and long-term graft loss, as well as correlations between systemic inflammation scores and inflammatory findings in biopsies 6 ...
    • Seasonal riverine inputs may affect diet and mercury bioaccumulation in Arctic coastal zooplankton 

      Carrasco, Nathalie; Mcgovern, Maeve; Evenset, Anita; Søreide, Janne E.; Arts, Michael T.; Jonsson, Sofi; Poste, Amanda Elizabeth (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-06)
      Climate change driven increases in permafrost thaw and terrestrial runoff are expected to facilitate the mobilization and transport of mercury (Hg) from catchment soils to coastal areas in the Arctic, potentially increasing Hg exposure of marine food webs. The main aim of this study was to determine the impacts of seasonal riverine inputs on land-ocean Hg transport, zooplankton diet and Hg bioaccumulation ...
    • Incidence of dementia over a period of 20 years in a Norwegian population 

      Johnsen, Bente; Martinaityte, Ieva; Wilsgaard, Tom; Schirmer, Henrik (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-09-29)
      INTRODUCTION: In Norway, the prevalence of dementia is higher than in demographically comparable, high income countries, but reliable incidence studies are lacking. This study calculated the incidence of age-specific dementia from 2000 to 2019.<p> <p>METHODS: Participants from The Tromsø Study (n = 44,214) were included. Participants with a dementia diagnosis (n = 2049 cases) were identified. ...
    • A Theoretical Discussion of How Common Understanding and Reflection Upon Need for Resources Can Prevent Risks Underlying Social Innovations 

      Gjertsen, Hege (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-30)
      The welfare state is facing complex challenges. Social innovation is considered as the solution to social challenges and socalled wicked problems, problems in the welfare state that are important, but difficult to solve. This implies being willing to take the risk that is involved when being innovative. A discussion of how different kinds of social innovations carry various risks and how some of ...
    • Modelling BK Polyomavirus dissemination and cytopathology using polarized human renal tubule epithelial cells 

      Lorentzen, Elias Myrvoll; Henriksen, Stian; Rinaldo, Christine Hanssen (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-08-28)
      Most humans have a lifelong imperceptible BK Polyomavirus (BKPyV) infection in epithelial cells lining the reno-urinary tract. In kidney transplant recipients, unrestricted high-level replication of donor-derived BKPyV in the allograft underlies polyomavirus-associated nephropathy, a condition with massive epithelial cell loss and inflammation causing premature allograft failure. There is limited ...
    • Variation of Mean Radiant Temperature in Rooms for Summer and Winter Conditions 

      Tamrakar, Stutee; Chen, Liguo; Sørensen, Bjørn Reidar (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-25)
      The standard for ergonomics of the thermal environment provides information on the calculation of optimal thermal comfort. Operative temperature (OT) is one of the essential elements of thermal comfort and is a function of air temperature, mean radiant temperature (MRT), and air velocity. This paper investigates the impact of diverse influences on MRT in an office room based on occupant position ...
    • Stress measurements in the weak layer during snow stability tests 

      Griesser, Silke; Pielmeier, Christine; Boutera Toft, Håvard; Reiweger, Ingrid (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-27)
      The snow compression test is a snow stability test where an isolated column of snow is progressively loaded by tapping on it to induce failure in a possible weak layer. The test result provides valuable information about the propensity of failure initiation within the snowpack. However, different persons might tap with different force and thus reduce the reproducibility of the test results. The ...
    • Exploring dog ownership in the lives of people with substance use disorder: a qualitative study 

      Kerr-Little, Andi; Bramness, Jørgen Gustav; Newberry, Ruth C.; Biong, Stian (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-09-27)
      Background: Recovery from substance use is commonly seen as a process of integrating social relationships and creating a sense of meaning in one’s life. Dog owners describe a close relationship with their dog that impacts many aspects of their everyday life. Yet for individuals with substance use disorder (SUD), little is known about how dog ownership could affect their lives. The aim of this study ...
    • Fictitious cases as a methodology to discuss sensitive health topics in focus groups 

      Gram, Emma Grundtvig; Brodersen, John Brandt; Hansen, Cæcilie; Pickles, Kristen; Smith, Jenna; Brandt Ryborg Jønsson, Alexandra (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-18)
      Purpose: It can be challenging to research aspects of people’s health behaviour, attitudes, and emotions due to the sensitive nature of these topics. We aimed to develop a novel methodology for discussing sensitive health topics, and explore the effectiveness in focus groups using prostate cancer and screening as an example.<p> <p>Method: We developed a fictitious case and employed it as a ...
    • No decline in drug overdose deaths in Norway: An ecological approach to understanding at-risk groups and the impact of interventions 

      Amundsen, Ellen Johanna; Melsom, Anne-Karine Markeng; Eriksen, Bjørn Odvar; Løchen, Maja-Lisa (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-09-28)
      Aim: This Norwegian case study examines groups at risk of drug overdose deaths, evidencebased harm reduction interventions, low-threshold services and treatment implemented, as well as trends in drug overdose deaths between 2010 and 2021. We aimed to explore the relevance of interventions for at-risk groups and discuss their potential impact on drug overdose trends. Method/data: Using an ecological ...
    • Are relative educational inequalities in multiple health behaviors widening? A longitudinal study of middle-aged adults in Northern Norway 

      Ibarra Sanchez, Ana Silvia; Chen, Gang; Wisløff, Torbjørn (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-08-22)
      Introduction: Educational inequality in multiple health behaviors is rarely monitored using data from the same individuals as they age. The aim of this study is to research changes in relative educational inequality in multiple variables related to health behavior (smoking, physical activity, alcohol intake, and body mass index), separately and collectively (healthy lifestyle), among middle-aged adults ...
    • Functional Outcomes at 6 and 12 Months Post-Injury in a Trauma Centre Population with Moderate-to-Severe Traumatic Injuries 

      Moksnes, Håkon Øgreid; Schafer, C.; Rasmussen, Mari Storli; Søberg, Helene L.; Røise, Olav; Anke, Audny Gabriele Wagner; Røe, Cecilie; Næss, Pål Aksel; Gaarder, Aslaug Christine; Helseth, Eirik; Hestnes, Morten; Brunborg, Cathrine; Andelic, Nada; Hellstrøm, Torgeir; Dahl, Hilde Margrete (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-08-15)
      This study aims to evaluate the global functional outcomes after moderate-to-severe traumatic injury at 6 and 12 months and to examine the sociodemographic and injury-related factors that predict these outcomes. A prospective cohort study was conducted in which trauma patients of all ages with a New Injury Severity Score > 9 who were discharged alive from two regional trauma centres in Norway ...
    • Are the stars aligned? Healthcare students’ conditions for negotiating tasks and competencies during interprofessional clinical placement 

      Törnqvist, Tove; Lindh Falk, Annika; Jensen, Catrine Buck; Iversen, Anita; Tingström, Pia (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-09-08)
      Background Healthcare students must learn to collaborate across professional boundaries so they can make use of each other’s knowledge and competencies in a way that benefits the patient. One aspect of interprofessional collaboration implies negotiating what needs to be done and by whom. Research, focused on the conditions under which students perform this negotiation when they are working together ...
    • Community carriage of ESBL-producing Escherichia coli and Klebsiella pneumoniae: a cross-sectional study of risk factors and comparative genomics of carriage and clinical isolates 

      Raffelsberger, Niclas Peter; Buczek, Dorota Julia; Svendsen, Kristian; Småbrekke, Lars; Pöntinen, Anna Kaarina; Löhr, Iren Høyland; Andreassen, Lotte Leonore Eivindsdatter; Simonsen, Gunnar Skov; Sundsfjord, Arnfinn Ståle; Gravningen, Kirsten; Samuelsen, Ørjan (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-12)
      The global prevalence of infections caused by extended-spectrum βlactamase-producing Enterobacterales (ESBL-E) is increasing, and for Escherichia coli, observations indicate that this is partly driven by community-onset cases. The ESBL-E population structure in the community is scarcely described, and data on risk factors for carriage are conflicting. Here, we report the prevalence and population ...
    • Impulsivity across severe mental disorders: a cross-sectional study of immune markers and psychopharmacotherapy 

      Hjell, Gabriela; Rokicki, Jaroslav; Szabo, Attila; Holst, Rene; Tesli, Natalia; Bell, Christina; Fischer-Vieler, Thomas; Werner, Maren Caroline Frogner; Lunding, Synve Hoffart; Elkjær Greenwood Ormerod, Monica Bettina; Johansen, Ingrid Torp; Djurovic, Srdjan; Ueland, Thor; Andreassen, Ole; Melle, Ingrid; Lagerberg, Trine Vik; Mørch-Johnsen, Lynn Egeland; Steen, Nils Eiel; Haukvik, Unn Kristin Hansen (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-09-07)
      Background Impulsivity is a transdiagnostic feature linked to severe clinical expression and a potential target for psychopharmacological strategies. Biological underpinnings are largely unknown, but involvement of immune dysregulation has been indicated, and the efects of psychopharmacological agents vary. We investigated if impul‑ sivity was associated with circulating immune marker levels and ...
    • Proarrhythmic changes in human cardiomyocytes during hypothermia by milrinone and isoprenaline, but not levosimendan: an experimental in vitro study 

      Selli, Anders Lund; Ghasemi, Mohammadreza; Watters, Taylor; Burton, Francis; Smith, Godfrey L; Dietrichs, Erik Sveberg (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-25)
      Background Accidental hypothermia, recognized by core temperature below 35 °C, is a lethal condition with a mortality rate up to 25%. Hypothermia-induced cardiac dysfunction causing increased total peripheral resistance and reduced cardiac output contributes to the high mortality rate in this patient group. Recent studies, in vivo and in vitro, have suggested levosimendan, milrinone and isoprenaline ...
    • The psychosocial impact of caring for children with Dravet Syndrome 

      Salom, Rafael; Aras, Luis Miguel; Piñero, Jessica; Dunabeitia Landaburu, Jon Andoni (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-08-25)
      This study examined the psychosocial impact on parents of children affected by Dravet Syndrome (DS), a rare drug-resistant developmental encephalopathic epileptic syndrome which affects children at an early age and that involves severe cognitive, behavioral, and motor impairments. DS has a major negative impact on caregivers, mainly on their physical and mental health, and on their social ...
    • Adherence to Guidelines for Acute Rehabilitation in the Norwegian Trauma Plan. 

      Schäfer, Christoph; Moksnes, Håkon Øgreid; Rasmussen, Mari Storli; Hellstrøm, Torgeir; Søberg, Helene L.; Røise, Olav; Røe, Cecilie; K Frisvold, Shirin; Bartnes, Kristian; Næss, Pål Aksel; Gaarder, Aslaug Christine; Helseth, Eirik; Brunborg, Cathrine; Andelic, Nada; Anke, Audny Gabriele Wagner (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-27)
      Objective: To evaluate adherence to 3 central operational recommendations for acute rehabilitation in the Norwegian trauma plan.<p> <p>Methods: A prospective multi-centre study of 538 adults with moderate and severe trauma with New Injury Severity Score >9. <p>Results: Adherence to the first recommendation, assessment by a physical medicine and rehabilitation physician within 72 h following ...
    • Controlled Interactivity - lean-back media experiences based on lean-forward technologies 

      Arntzen, Ingar Mæhlum (Conference object; Konferansebidrag, 2023-11-08)
      Interactive rendering technologies like maps, timelines, and plots can be powerful tools for data visualization and exploration. In the context of media, such tools are often referred to as lean-forward, implying that the user is actively telling his own story by using control primitives such as skip, pan, tilt, adjust, scroll, rewind, reorder, zoom, play and more. We are interested in using such ...
    • Local ecological knowledge and multidisciplinary approach lead to discovery of hidden biodiversity in the deep ocean of Labrador, Canada 

      Coté, David; Neves, Barbara; Angnatok, Joey; Bartlett, Wilfred; Edinger, Evan N; Gullage, Lauren; Laing, Rodd; Normandeau, Alexandre; Hayes, Vonda; Sherwood, Owen; Geoffroy, Maxime (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11)
      nternational commitments to preserve global biodiversity target the protection of 30% of marine habitats by 2030. The lack of even basic knowledge of many marine areas (e.g., deep oceans) combined with short timelines require integrative knowledge and multidisciplinary techniques to be used to efficiently identify areas worthy of protection. Here we outline a case study of the discovery of the ...