Artikler, rapporter og annet (medisinsk biologi): Recent submissions

Now showing items 921-940 of 1059

    • Forty years of allocated seats for Sami medical students : has preferential admission worked? 

      Gaski, Margrete; Abelsen, Birgit; Hasvold, Toralf (Journal article; Tidsskriftartikkel; Peer reviewed, 2008)
      This article examines the effects of a special admission policy for Sami medical students in Norway. In the 1960s, public health and health care were found to be poorer in Sami communities than in the rest of Norway. There were few doctors and none of them spoke Sami. Sami school leavers found it difficult to gain admittance to medical schools. In response to this situation, the medical faculty at ...

    • Use of Health care in the main area of Sami habitation in Norway : catching up with national expenditure rates 

      Gaski, Margrete; Melhus, Marita; Deraas, Trygve Sigvart; Førde, Olav Helge (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      For many years political and professional concerns have centred on the health service access of Norway’s modern Indigenous Sami people. Thirty years ago, a study determined that a low rate of health expenditure on Sami patients had lead to inferior health services for the Sami people, with their average consultation rate 6 times lower than the Norwegian national average. Since 1980, there have been ...

    • The recent transfer of a homing endonuclease gene 

      Haugen, Peik; Wikmark, Odd-Gunnar; Vader, Anna; Coucheron, Dag H.; Sjøttem, Eva; Johansen, Steinar D. (Journal article; Tidsskriftartikkel; Peer reviewed, 2005)
      The myxomycete Didymium iridis (isolate Panama 2) contains a mobile group I intron named Dir.S956-1 after position 956 in the nuclear small subunit (SSU) rRNA gene. The intron is efficiently spread through homing by the intron-encoded homing endonuclease I-DirI. Homing endonuclease genes (HEGs) usually spread with their associated introns as a unit, but infrequently also spread independent of ...

    • HPV mRNA test in women with minor cervical lesions : experience of the University Hospital of North Norway 

      Sørbye, Sveinung Wergeland; Fismen, Silje; Gutteberg, Tore Jarl; Mortensen, Elin (Journal article; Tidsskriftartikkel; Peer reviewed, 2010)
      In the Norwegian Cervical Cancer Screening Programme tests for detection of human papillomavirus (HPV) are used to triage women with minor cytological cervical lesions. The material in this study comprises samples from 1798 women in the period 2006–2008. The HPV test was performed according to the guidelines of the Norwegian Cancer Registry. The HPV mRNA test (PreTect HPV-Proofer) detects and types ...

    • Asthma,chronic obstructive pulmonary disease, or both? Diagnostic labeling and spirometry in primary care patients aged 40 years or more 

      Melbye, Hasse; Drivenes, Elin; Leinan, Tone (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      To describe symptoms and lung function in patients registered with asthma or chronic obstructive pulmonary disease (COPD) in primary care and to examine how spirometry findings fit with general practitioners’ (GPs) diagnoses. Patients aged ≥40 years with a diagnosis of asthma or COPD registered in the electronic medical record during the previous 5 years were recruited at seven GP offices in Norway ...

    • Mindfulness-Based Stress Reduction for Integrative Cancer Care : a Summary of Evidence 

      Musial, Frauke; Büssing, Arndt; Heusser, Peter; Choi, Kyung-Eun; Ostermann, Thomas (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      This paper provides a comprehensive overview of the relevant existing evidence, and critically appraises the use of mindfulness-based stress reduction (MBSR) in cancer care. Furthermore, a meta-analysis was conducted in order to investigate the effect of MBSR on quality of life (QoL), mood, and distress. Besides 6 reviews (5 systematic, 1 meta-analytic) which are reported separately, a total of 19 ...

    • Diet and lifestyle of the Sami of southern Lapland in the 1930s-1950s and today 

      Nilsson, Lena M.; Dahlgren, Lars; Johansson, Ingegerd; Brustad, Magritt; Sjolander, Per; Van Guelpen, Bethany (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      To describe the lifestyle of the Sami of southern Lapland 50 to 70 years ago in relation to the present-day Sami and non-Sami populations and, thereby, to provide a basis for future studies of culturally related determinants of health and illness. A qualitative analysis, and a quantitative comparison of Sami and non-Sami groups. Semi-structured interviews were conducted with 20 elderly Sami ...

    • The effect of traditional cupping on pain and mechanical thresholds in patients with chronic nonspecific neck pain : a randomised controlled pilot study 

      Lauche, Romy; Cramer, Holger; Hohmann, Claudia; Choi, Kyung-Eun; Rampp, Thomas; Saha, Felix Joyonto; Musial, Frauke; Langhorst, Jost; Dobos, Gustav J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Cupping has been used since antiquity in the treatment of pain conditions. In this pilot study, we investigated the effect of traditional cupping therapy on chronic nonspecific neck pain (CNP) and mechanical sensory thresholds. Fifty CNP patients were randomly assigned to treatment (TG, n = 25) or waiting list control group (WL, n = 25). TG received a single cupping treatment. Pain at rest (PR), ...

    • Dental caries experience among 15-year-old adolescents in north-west Russia 

      Gorbatova, Maria A.; Gorbatova, Lyubov N.; Grjibovski, Andrej (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      To estimate the prevalence and experience of dental caries among 15-year-old adolescents in north-west Russia between 2007 and 2008. Study design. A cross-sectional study. In total, 352 adolescents at the age of 15 were selected at random from 3 urban and 4 rural areas in the Arkhangelsk region. Girls comprised 53.4% of the sample. Caries experience was assessed at D3 level by a single calibrated ...

    • Age- and Gender-Associated Staphylococcus aureus spa Types Found among Nasal Carriers in a General Population: the Tromsø Staph and Skin Study. 

      Sangvik, Maria; Olsen, Renate Slind; Olsen, Karina; Simonsen, Gunnar Skov; Furberg, Anne-Sofie; Sollid, johanna u ericson (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Staphylococcus aureus nasal carriers risk autoinfection; however, knowledge about the factors that make specific strains successful colonizers is limited. This study was undertaken to identify the most successful S. aureus clones in nasal carriers and compare their distribution among host groups. The population structure of S. aureus isolates from healthy adults was investigated by spa typing 1,981 ...

    • Pax6 Represses Androgen Receptor-Mediated Transactivation by Inhibiting Recruitment of the Coactivator SPBP 

      Elvenes, Julianne; Thomassen, Ernst Ivan; Johnsen, Sylvia Sagen; Kaino, Katrine; Sjøttem, Eva; Johansen, Terje (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      The androgen receptor (AR) has a central role in development and maintenance of the male reproductive system and in the etiology of prostate cancer. The transcription factor Pax6 has recently been reported to act as a repressor of AR and to be hypermethylated in prostate cancer cells. SPBP is a transcriptional regulator that previously has been shown to enhance the activity of Pax6. In this study ...

    • The International Collaboration on Complementary Therapy Resources (ICCR) : working together to improve online CAM information 

      Pilkington, Karen; Gamst, are; Liu, Irene; Ostermann, Thomas; Pinto, Dimitry; Richardon, Janet (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Use of the Internet to find health information is increasing dramatically but the quality of information, particularly on complementary and alternative medicine (CAM) is variable. The International Collaboration on Complementary Therapy Resources (ICCR) involves collaboration between the national CAM information centers in Australia, Denmark, Norway, the United Kingdom, and the United States, and a ...

    • Serum osteoprotegerin levels are related to height loss : the Tromsø Study 

      Jørgensen, Lone; Hansen, John-Bjarne; Brox, Jan; Mathiesen, Ellisiv B.; Vik, Anders; Jacobsen, Bjarne Koster (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Severe loss of body height is often a consequence of osteoporotic vertebral fractures. Osteoprotegerin (OPG) and receptor activator of nuclear factor-kB ligand (RANKL) are cytokines essential for the regulation of bone resorption. The aim of this study was to assess the relationship between the OPG/RANKL system and height loss. A total of 4,435 inhabitants from the municipality of Tromsø, ...

    • BKV Agnoprotein Interacts with alpha-Soluble N-Ethylmaleimide-Sensitive Fusion Attachment Protein, and Negatively Influences Transport of VSVG-EGFP 

      Johannessen, Mona; Walquist, Mari; Gerits, Nancy; Dragset, Marte Singsås; Spang, Anne; Moens, Ugo (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      The human polyomavirus BK (BKV) infects humans worldwide and establishes a persistent infection in the kidney. The BK virus genome encodes three regulatory proteins, large and small tumor-antigen and the agnoprotein, as well as the capsid proteins VP1 to VP3. Agnoprotein is conserved among BKV, JC virus (JCV) and SV40, and agnoprotein-deficient mutants reveal reduced viral propagation. Studies with ...

    • Characterization of mitochondrial mRNAs in codfish reveals unique features compared to mammals 

      Coucheron, Dag-Hugo; Nymark, Marianne; Breines, Ragna; Karlsen, Bård Ove; Andreassen, morten; Jørgensen, Tor Erik; Moum, Truls; Johansen, Steinar Daae (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Expression and processing of mitochondrial gene transcripts are fundamental to mitochondrial function, but information from early vertebrates like teleost fishes is essentially lacking. We have analyzed mitogenome sequences of ten codfishes (family Gadidae), and provide complete sequences from three new species (Saithe, Pollack and Blue whiting). Characterization of the mitochondrial mRNAs in Saithe ...

    • Indications of decreasing human PTS concentrations in North West Russia 

      Rylander, Charlotta; Sandanger, Torkjel Manning; Petrenya, Natalia Nikolaevna; Konoplev, AV; Bojko, E; Odland, jon Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      The Russian Arctic covers an enormous landmass with diverse environments. It inhabits more than 20 different ethnic groups, all of them with various living conditions and food traditions. Indigenous populations with a traditional way of living are exposed to a large number of anthropogenic pollutants, such as persistent organic pollutants (POPs) and toxic metals, mainly through the diet. Human ...

    • Staphylococcus aureus nasal carriage is associated with serum 25-hydroxyvitamin D levels, gender and smoking status. The Tromsø Staph and Skin Study 

      Olsen, Karina; Falch, Birgit Margrethe; Danielsen, Kjersti; Johannessen, Mona; Sollid, Johanna U Ericson; Thune, Inger; Grimnes, Guri; Jorde, Rolf; Simonsen, Gunnar Skov; Furberg, Anne-Sofie (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Vitamin D induces the expression of antimicrobial peptides with activity against Staphylococcus aureus. Thus, we studied the association between serum 25-hydroxyvitamin D (25(OH)D) and S. aureus nasal colonization and carriage. Nasal swabs, blood samples and clinical data from 2,115 women and 1,674 men, aged 30–87 years, were collected in the Tromsø Staph and Skin Study 2007–08, as part of the ...

    • Precaution or Integrated Responsibility Approach to Nanovaccines in Fish Farming? A Critical Appraisal of the UNESCO Precautionary Principle 

      Myhr, Anne Ingeborg; Myskja, Bjørn Kåre (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Nanoparticles have multifaceted advantages in drug administration as vaccine delivery and hence hold promises for improving protection of farmed fish against diseases caused by pathogens. However, there are concerns that the benefits associated with distribution of nanoparticles may also be accompanied with risks to the environment and health. The complexity of the natural and social systems involved ...

    • A Genome-Wide Association Study of Upper Aerodigestive Tract Cancers Conducted within the INHANCE Consortium 

      McKay, James D.; Truong, Therese; Gaborieau, V; Chabrier, Amelie; Chuang, Shu-Chun; Byrnes, G; Zaridze, D; Shangina, O; Szeszenia-Dabrowska, N; Lissowska, Jolanta; Rudnai, P; Fabianova, E; Bucur, A; Bencko, V; Holcatova, I; Janout, V; Foretova, L; Lagiou, Pagona; Trichopoulos, Dimitrios; Benhamou, S; Ahrens, Wolfgang; Bouchardy, C; Merletti, F; Richiardi, L; Talamini, R; Simonato, L; Barzan, L; Kjærheim, Kristina; Macfarlane, G; Agudo, Antonio; Macfarlane, Tatiana V.; Canova, C; Castellsague, X; Conway, DI; Lowry, R; Healy, CM; McKinney, PA; Toner, ME; Znaor, A; Menezes, A; Curado, MP; Koifman, S; Neto, JE; Wünsch-Filho, V; Boccia, S; Arzani, D; Garrote, LF; Cadoni, G; Olshan, AF; Weissler, MC; Luo, JC; Funkhouser, WK; Lubinski, Jan; Lener, M; Trubicka, J; Schwartz, SM; Oszutowska, D; Doody, DR; Chen, C; Fish, S; Lazarus, P; Muscat, JE; Gallagher, CJ; Zhang, Zuo-Feng; Chang, SC; Wei, QY; Sturgis, EM; Franceschi, S; Kelsey, KT; Wang, LE; Herrero, R; Marsit, CJ; McClean, MD; Romkes, M; Nelson, HH; Buch, S; Nukui, T; Zhong, SL; Lacko, M; Manni, JJ; McLaughlin, J; Hung, RJ; Peters, WHM; Vatten, Lars Johan; Njølstad, Inger; Goodman, GE; Field, JK; Palli, D; Liloglou, T; Clavel-Chapelon, F; Vineis, P; Krogh, V; Tumino, R; Panico, S; Martinez, Carmen; Gonzalez, CA; Quiros, JR; Navarro, C; Larranaga, N; Khaw, KT; Ardanaz, E; Key, T; Peeters, PHM; Bueno-De-Mesquita, H. Bas; Boeing, H; Overvad, K; Trichopoulou, A; Linseisen, J; Hallmans, G; Tjønneland, Anne; Riboli, Elio; Kumle, Merethe; Valk, K; Voodern, Tonu; Metspalu, Andres; Boland, A; Zelenika, D; Delepine, M; Foglio, M; Lechner, D; Blanché, Hélène; Gut, Ivo G.; Galan, P; Hashibe, Mia; Heath, Simon; Hayes, Richard B.; Lathrop, Mark; Boffetta, Paolo; Brennan, Paul (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Genome-wide association studies (GWAS) have been successful in identifying common genetic variation involved in susceptibility to etiologically complex disease. We conducted a GWAS to identify common genetic variation involved in susceptibility to upper aero-digestive tract (UADT) cancers. Genome-wide genotyping was carried out using the Illumina HumanHap300 beadchips in 2,091 UADT cancer cases and ...

    • Fine Mapping of Five Loci Associated with Low-Density Lipoprotein Cholesterol Detects Variants That Double the Explained Heritability 

      Sanna, S; Li, BS; Mulas, A; Sidore, C; Kang, HM; Jackson, AU; Piras, MG; Usala, G; Maninchedda, G; Sassu, A; Serra, F; Palmas, MA; Wood, WH; Njølstad, Inger; Laakso, M; Hveem, Kristian; Tuomilehto, J; Lakka, TA; Rauramaa, R; Boehnke, M; Cucca, F; Uda, M; Schlessinger, D; Nagaraja, R; Abecasis, GR (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Complex trait genome-wide association studies (GWAS) provide an efficient strategy for evaluating large numbers of common variants in large numbers of individuals and for identifying trait-associated variants. Nevertheless, GWAS often leave much of the trait heritability unexplained. We hypothesized that some of this unexplained heritability might be due to common and rare variants that reside in ...